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Shyama Nandakumar

@shyama13.bsky.social
222 followers 456 following 37 posts

Drosophila biologist studying cell stress in growth and development. Will talk to you about polyploidy at all times. Microscope and camera nerd. Always willing to discuss science + philosophy + sports www.shyamanandakumar.in

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Shyama Nandakumar @shyama13.bsky.social · 04/10/2026
@flybase.bsky.social @fly-eds.bsky.social @bdsc.bsky.social
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Shefali @iamshef.bsky.social · 11/09/2026
Hey #Drosophila folks - the #flycross #mentee survey is open for #grad students, #postdoc and #pretenure faculty. ~95 mentors from across the world, with diverse expertise. The co-chairs @shyama13.bsky.social and @jocmcdonald.bsky.social have done a phenomenal work in taking the program forward 🎉
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MU-Peter Shimon 🀄 @mu-peter.bsky.social · 18/09/2026
Missing from the archaeological record, fiber innovations like string played a huge role in the daily lives of our ancestors. Researchers are working to weave together insights from traces they left behind. Rope, Twine and Thread: Invisible Technologies of the Stone Age🏺🧪 nautil.us/rope-twine-a...
Using string or cord to attach stone tools to a handle or shaft — known as hafting — transformed the sharpened rocks into new instruments with expanded functions, including axes, arrows and spears. The stone dagger resembles one carried by Ötzi the Iceman. Credit: B. Taub / Knowable Magazine
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Shefali @iamshef.bsky.social · 04/09/2026
Hey #Drosophila folks ! The deadline is approaching - please consider filling up the mentoring survey and support our next generation and #earlycareer fly scientists! @flybase.bsky.social @fly-eds.bsky.social @evodevopanam.bsky.social @official-smbe.bsky.social @the-node.bsky.social
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Shyama Nandakumar @shyama13.bsky.social · 04/09/2026
Please sign up to mentor! The time commitment is minimal but it makes a real difference. @genetics-gsa.bsky.social @fly-eds.bsky.social @interactivefly.bsky.social @flybase.bsky.social @fly-broadcast.bsky.social
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Shyama Nandakumar @shyama13.bsky.social · 31/08/2026
#drosophila folks, the Mentor survey for FlyCROSS closes soon! Please sign up using the link below, please RT and spread the word!! @flybase.bsky.social @fly-eds.bsky.social @fly-jedi.bsky.social @genetics-gsa.bsky.social @iamshef.bsky.social docs.google.com/forms/d/e/1F...
docs.google.com
2026 FlyCROSS Survey For Mentors
We appreciate you taking the time and volunteering to be a mentor! Add dmelcross@gmail.com to your email address book or safe sender list, so that you can receive our emails. To be a participating men...
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PLOS Biology @plosbiology.org · 25/08/2026
What are the genetic mechanisms for the #evolution of novel traits? This study by @brhopkins92.bsky.social &co links #Drosophila sex comb teeth to expression changes within ancestral cells, leading to diverged metabolic/developmental rates, and a novel structure. 🧪 #AcademicSky plos.io/4gQOnZK
Graphical abstract on the gain of a novel trait in Drosophila. The teeth of the recently evolved, male-specific Drosophila sex comb evolved from a more ancient organ, the mechanosensory bristle. We show that changes in the expression of genes that are shared between mechanosensory bristle and sex comb teeth cells lead to changes in a variety of fundamental cellular processes that together enable the morphological transformation.

The photo, phylogeny, general design are those of the corresponding author(s). They made the bristle schematics in biorender and the fly silhouette is their modified drawing of D. melanogaster from SciDraw (https://doi.org/10.5281/zenodo.3925939).
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Shyama Nandakumar @shyama13.bsky.social · 20/08/2026
Please note that you can sign up to be a FlyCROSS mentor: 1.even if you used Drosophila in the past but do not work with it anymore 2.even if you are in Industry not (especially if you are in Industry or non-academic careers!) 3. even if you are retired! #drosophila
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Shyama Nandakumar @shyama13.bsky.social · 20/08/2026
Please sign up to mentor as a part of FlyCROSS! @genetics-gsa.bsky.social @flybase.bsky.social @fly-eds.bsky.social #drosophila
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Shyama Nandakumar @shyama13.bsky.social · 14/08/2026
#drosophila #FlyCROSS #mentorship Apply Now to serve as a mentor with the FlyCROSS mentor-mentee matching program! If you have tried scanning the QR code and it did not work, please use link below: forms.gle/JDXeP1kNFftL...
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Shyama Nandakumar @shyama13.bsky.social · 14/08/2026
#drosophila #FlyCROSS #mentorship Apply Now to serve as a mentor with the FlyCROSS mentor-mentee matching program! If you have tried scanning the QR code and it did not work, please use link below: forms.gle/JDXeP1kNFftL...
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Shyama Nandakumar @shyama13.bsky.social · 11/08/2026
If you haven't already, please sign up to be a mentor for the FlyCROSS program! #drosophila #mentorship
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Shyama Nandakumar @shyama13.bsky.social · 06/08/2026
#Drosophila
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Shyama Nandakumar @shyama13.bsky.social · 06/08/2026
@flybase.bsky.social @fly-eds.bsky.social @interactivefly.bsky.social @fly-broadcast.bsky.social @fly-jedi.bsky.social @genetics-gsa.bsky.social
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Shefali @iamshef.bsky.social · 04/08/2026
📢📢 #Drpsophila community! #FlyCROSS surveys are open for #mentors. The current chairs @shyama13.bsky.social and @jocmcdonald.bsky.social alongside the committee members have put in a lot of effort to begin the third cycle of this mentoring program. You may have already received an invite from GSA.
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Buttitta Lab @buttittalab.bsky.social · 16/05/2026
Check out this amazing lineup for the FASEB Cell Cycle conference this July. Abstract deadline is rapidly approaching on June 1st!
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Neha Ghosh @nehaghosh.bsky.social · 21/03/2026
I am excited to share my new paper in @plosbiology.org . Here we show the role of chitin, a polysaccharide, in controlling the shape of the fly corneal lens. journals.plos.org/plosbiology/...
journals.plos.org
Curvature of the Drosophila corneal lens depends on localized chitin secretion
How does the corneal lens in the fly eye acquire its light-focusing shape? This study shows that centrally located cells produce large amounts of chitin to form the thick central corneal lens, while p...
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Ben Hopkins @brhopkins92.bsky.social · 06/03/2026
Quick plug for our new resource, the Drosophila Species Stock Exchange. This is a database and mailing list that documents species currently in culture and the labs holding them. If you want to know more or sign up then please get in touch. See attached for more info and please share!
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Shyama Nandakumar @shyama13.bsky.social · 08/03/2026
Thank you Shefali for all your dedicated and thoughtful service and wonderful contributions to the fly community!
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Noah Whiteman @nkwhiteman.bsky.social · 05/03/2026
Proud of Dr @tarnopol.bsky.social who received the Sandler Award for “Outstanding Drosophila Thesis” at the fly meeting #Dros26 in Chicago this evening! @genetics-gsa.bsky.social
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Shefali @iamshef.bsky.social · 27/02/2026
#Drosophila #FlyCROSS 2025-26 updates - 84 mentor-mentee matches were made ✅ Out of which 90 % of mentees were matched to one of their preferred mentors. Keep and eye for the future program notifications. See you all at #Dros26 Below are the mentee demographics and response summary. (1/n)
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Shyama Nandakumar @shyama13.bsky.social · 26/02/2026
Please dm or email me if you want to help judge posters at fly meeting next week!
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Shyama Nandakumar @shyama13.bsky.social · 12/02/2026
Hello fly folks! If you are a postdoc or junior faculty attending the @genetics-gsa.bsky.social #Dros26 #flymeeting in Chicago, and interested in helping judge trainee posters, please comment or DM me! Topic: Stem Cells/Regeneration/Tissue Injury Please RT @flybase.bsky.social @bdsc.bsky.social
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Crystal Rogers, PhD @rogerslabucd.bsky.social · 08/12/2025
Applications for Life Science Editors Foundation JEDI awards are open! Do you have a paper for grant you are working on that could use a little editing help or guidance? Please apply! lifescienceeditors.org/apply/
lifescienceeditors.org
Apply for a JEDI Award - Life Science Editors Foundation
“Before this backlash worsens, DEI advocates, the scientific community, universities, and federal agencies need to collectively call out the dangers of setting aside DEI and come up with robust ways t...
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Wallace Marshall @wallaceucsf.bsky.social · 05/12/2025
Cells can hunt prey, solve mazes, and learn from past experience. Does this mean they can think, at some level? Find out more at our upcoming session on "Cell Behavior and Cognition" at the ASCB/EMBO #cellbio2025 meeting, Saturday 1-3 pm rm 115.
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Harmit Singh Malik @harmitmalik.bsky.social · 12/11/2025
Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on. (Please repost to reach a broad audience.)
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Harmit Singh Malik @harmitmalik.bsky.social · 12/11/2025
If you are enthusiastic, this is an ideal position for you to hone your leadership skills. Many initiatives, like FlyCROSS mentor-match, were the brainchild of our trainee reps. If you want to know more or be considered, reach out to me, @iamshef.bsky.social, or @shyama13.bsky.social by Nov 17! 3/
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Shyama Nandakumar @shyama13.bsky.social · 12/11/2025
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 08/11/2025
You are embarrassing yourself by lauding this monster. Do you defend these views, which he held lifelong. Where is the "nuance in these words?" Shame! liorpachter.wordpress.com/2018/05/18/j...
liorpachter.wordpress.com
James Watson in his own words
“Some anti-Semitism is justified” “Whenever you interview fat people, you feel bad, because you know you’re not going to hire them” “Japan should be bombed for d…
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Terry McGlynn @hormiga.bsky.social · 07/11/2025
Hey folks, as news of Watson's demise spreads, please don't set aside his weighty legacy of misogyny and racism. He was truly among the worst of us. www.vox.com/2019/1/15/18...
vox.com
DNA scientist James Watson has a remarkably long history of sexist, racist public comments
“People say it would be terrible if we made all girls pretty,” he said in 2003. “I think it would be great.”
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Christopher Michel @christophermichel.com · 04/11/2025
Mariana Wolfner Mariana Wolfner has spent her life studying a creature so small it could rest on the tip of her finger. In her hands, the fruit fly Drosophila melanogaster becomes something extraordinary, a key to understanding how life is shaped, sustained, and passed on. On a windy fall…
explorers.com
Mariana Wolfner
Mariana Wolfner has spent her life studying a creature so small it could rest on the tip of her finger. In her hands, the fruit fly Drosophila melanogaster becomes something extraordinary, a key to understanding how life is shaped, sustained, and passed on. On a windy fall afternoon at Cornell, she sat surrounded by papers, notes, and journals. The light came through the window in soft bands as she lifted a golden model of a fly and smiled.
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Society for Developmental Biology @socdevbio.bsky.social · 03/09/2025
The 2025-2026 season of the Ethel Browne Harvey Postdoc Seminar kicks off Friday, September 12 at 3 pm Eastern Time with @sarahcolijn.bsky.social‬ of Washington Univ in St. Louis and @shyama13.bsky.social‬ of the Univ of Pittsburgh. Register today and join us. bit.ly/4649fWS #SDBPostdocSeminar
Society for Developmental Biology Ethel Browne Harvey Postdoctoral Seminar Series
Friday, September 12, 2025, 3:00pm - 4:00 pm Eastern Time
Sarah Colijn (Washington University in St. Louis)
Novel roles for centriolar protein WDR90 in endothelial cells and cardiac tissue
Shyama Nandakumar (University of Pittsburgh)
Ring canals in the larval adipose of Drosophila buffer stress response
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Genetics Society of America @genetics-gsa.bsky.social · 02/09/2025
Today we celebrate 1945 GSA President & Nobel laureate Barbara McClintock. Continue her legacy—nominate for the 2026 GSA Awards by Oct 1, 2025. 🔗 buff.ly/bIdKqcw
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Lesley Weaver @lesleynweaver.bsky.social · 26/08/2025
My lab’s newest preprint is now available. www.biorxiv.org/content/10.1...
biorxiv.org
Adipocyte-Derived Amino Acid Storage Proteins are Required for Germline Stem Cell Maintenance in Adult Drosophila Females
Tissue homeostasis is dependent on precise coordination between endocrine organs in response to changes in organism physiology. Secreted circulating factors from adipocytes (called adipokines) regulat...
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Shefali @iamshef.bsky.social · 21/07/2025
The #Flyboard and #FlyCROSS committee including me, Laurel @shyama13.bsky.social @jocmcdonald.bsky.social @frankmac.bsky.social @armstrongflylab.bsky.social & Jonathan look forward to having you on board.
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Lydia Grmai, Ph.D. @lydiagrmai.bsky.social · 15/07/2025
new review alert❗️ thought your neighborhood stress response pathway (ISR) only dealt in stress adaptation? well, maybe so. but many cells are apparently quite “stressed out” - even healthy ones. see quoted thread by my phenom co-author @shyama13.bsky.social for a summary! ⬇️
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Shyama Nandakumar @shyama13.bsky.social · 15/07/2025
Hello fellow scientists, I'm thrilled to share with you a state of the art review that @lydiagrmai.bsky.social , the bsky-less Deepika Vasudevan and I have been working on for >1 year! Keep reading...! febs.onlinelibrary.wiley.com/doi/full/10....
febs.onlinelibrary.wiley.com
FEBS Press
Integrated stress response (ISR), an evolutionarily conserved eukaryotic stress-adaptive program in eukaryotes, has also been implicated in homeostatic functions. This review covers a broad body of l....
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Saccharomyces Genome Database @yeastgenome.bsky.social · 09/06/2025
FlyBase needs your help! Because of recent changes to government funding, the NIH grant that supported FlyBase has been "terminated." flybase.org
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Shyama Nandakumar @shyama13.bsky.social · 12/06/2025
New paper alert. The fat body in Drosophila larvae is comprised of pairs of adipocytes that are connected to one another throughout larval development! Ring canals here are v.v.small, allow selective organellar cargo transport, mediate stress tolerance and more....! Full thread coming soon!
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bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · 11/06/2025
Ring canals in the larval adipose of Drosophila buffer stress response www.biorxiv.org/content/10.1101/202…
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Buttitta Lab @buttittalab.bsky.social · 05/06/2025
Thank you for the highlight of our work! #drosophila #cancer model.
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Shefali @iamshef.bsky.social · 03/06/2025
Hey #Drosophila folks ! #FlyCROSS is back and #Mentor surveys are open NOW ! If you're a faculty/postdoc/ equivalent in any scientific career & have #Drosophila research experience - we'd be delighted to have you as mentors to empower early career scientists in the #Dros community !
docs.google.com
Summer 2025 Survey For Mentors : FlyCROSS Mentor Mentee Matching Program
We appreciate you taking the time and volunteering to be a mentor! Add dmelcross@gmail.com to your email address book or safe sender list, so that you can receive our emails. To be a participating me...
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Harmit Singh Malik @harmitmalik.bsky.social · 21/03/2025
Drosophila folks at the @genetics-gsa.bsky.social Fly meeting please take some time to thank the amazing organizers who put in a lot of hard work: genetics-gsa.org/drosophila-2... Special thanks to GSA folks especially the tireless Suzy Brown (who appears to run entirely on diet Mountain Dew)
genetics-gsa.org
Organizers - 66th Annual Drosophila Research Conference
Visit our website to learn more.
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Prof Jess @pr0fjess.bsky.social · 20/03/2025
Really looking forward to this workshop!
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Shyama Nandakumar @shyama13.bsky.social · 20/03/2025
#Dros25 workshop alert! Today at 8pm, Pacific Ballroom C - Go Big or Go Home : Polyploidy on the Fly. Excited to host this with @gavinrrice.bsky.social
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Shefali @iamshef.bsky.social · 11/03/2025
The committee has unanimously voted to have the next cycle in summer/early fall - so early career scientists, keep an eye out for announcements !!! 👀 If you have suggestions/ideas for the future cycles, please feel free to reach out !!
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Alissa Armstrong @armstrongflylab.bsky.social · 11/03/2025
#drosophila #mentoring
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Shyama Nandakumar @shyama13.bsky.social · 26/02/2025
#Drosophila folks, anyone looking for a roommate (Female) at fly meeting? I know someone who would appreciate a roommate. Comment/DM for details
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Alissa Armstrong @armstrongflylab.bsky.social · 24/02/2025
Beyond thrilled - I’ve been awarded an NSF CAREER grant! I get to continue making scientific discoveries, training the next generation of researchers, & sharing knowledge about the scientific enterprise with the general public. This support is much needed, personally & professionally…let’s GOOO!!!
Screenshot of part of a notice of award for an NSF CAREER grant: Regulation of Drosophila melanogaster oogenesis by ovarian and adipose tissue amino acid sensing signaling pathways
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Shefali @iamshef.bsky.social · 29/01/2025
Bringing in some joy - FlyCROSS committee including me, Laurel Raftery, @jocmcdonald.bsky.social @armstrongflylab.bsky.social @shyama13.bsky.social , Frank Macabenta and Jonathan Andrews have completed the #Drosophila mentor-mentee matching process ! Emails will start rolling out in mid-Feb.
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