Gina DeNicola @ginadenicola.bsky.social · 15/07/2026⚠️ Abstracts due by July 24th! FREE virtual 2026 Cancer Metabolism Showcase & Workshop — September 8–9 ✅ Short talks & poster sessions ✅ Career panels & workshops ✅ Career Keynote from Ralph DeBerardinis 📝 Submit & register: www.cancermetabolismshowcase.org Please share!cancermetabolismshowcase.org2026 Cancer Metabolism Showcase & Workshop 031
Reposted by Gina DeNicolaCristina Muñoz Pinedo @crismunozp.bsky.social · 04/05/2026Very interesting articles about cancer metabolism this month, and insightful reviews. Highlighting fresh articles and comments about cysteine and glutathione from @lucasbsullivan.bsky.social @ginadenicola.bsky.social @harrislab.bsky.social and others metabolist.wordpress.com/2026/05/04/m...metabolist.wordpress.comMetaboList – April 2026Cystine / Glutathione / NADPH SLC33A1 exports oxidized glutathione to maintain endoplasmic reticulum redox homeostasis Shanshan Liu (刘珊珊), Mark Gad, Caifan Li (李采蘩), Kevin Cho, Yuyang Liu (刘雨洋),… 053
Reposted by Gina DeNicolaLucas Sullivan @lucasbsullivan.bsky.social · 08/04/2026Pleased to share our recent work out today in @natmetabolism.nature.com. This study addresses a longstanding mystery - NRF2-driven cancers increase cysteine acquisition (via xCT) by ~5x - so where does all that cysteine go? 25023
Reposted by Gina DeNicolaJulien Sage @juliensage.bsky.social · 31/03/2026New preprint from the lab! Close collaboration with Silvia von Karstedt @vonkarstedtlab.bsky.social and her lab. We find that #SCLC cells are strikingly dependent on exogenous cysteine #LungCancer #CancerMetabolism #Ferroptosis 🧵 biorxiv.org/content/10.64898/2026.03.27.714827v1 166
Reposted by Gina DeNicolacniostopcancer.bsky.social @cniostopcancer.bsky.social · 17/02/2026Second session at #CFM_MetCanc on the relationship between exercise, nutritional signals and cancer prevention. Speakers: Mark Febbraio, @monashuniversity.bsky.social Gina DeNicola @ginadenicola.bsky.social, Moffit Cancer Center ✍️ bit.ly/45jaORu Sponsored by @caixaresearch.bsky.social 032
Reposted by Gina DeNicolaMuir Lab @muirlab.bsky.social · 01/02/2026Very helpful methods and protocol! www.sciexplor.com/articles/fos... Great work @ginadenicola.bsky.social and team!sciexplor.comBest practices for cysteine analysisAccurate measurement of cysteine and related thiol-containing metabolites is essential for understanding cellular redox regulation. However, the intrinsic reactivity and instability of cysteine presen... 053
Reposted by Gina DeNicolaPhillip White @phillipjwhitephd.bsky.social · 13/01/2026Excited to announce that registration is officially open for #METPHYS2026! All meeting details can be found here: www.sablesys.com/metphys-the-... 01613
Gina DeNicola @ginadenicola.bsky.social · 06/01/2026Interested in stable isotope infusions but daunted by jugular catheter surgery? New from postdoc @kimyumi0201.bsky.social: our simple tail vein catheter method enables anesthesia-free infusions in awake, freely moving mice. 🧵 21710
Gina DeNicola @ginadenicola.bsky.social · 23/11/2025Got up at 5AM today to do the Miles for Moffitt 10K with Basma from my lab. Success! 0160
Reposted by Gina DeNicolaKatsu Funai @katsufunai.bsky.social · 28/08/2025We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share! @uofunuip.bsky.socialnature.comOpen Rank, Tenure Track Position – Metabolic Physiology - Salt Lake City, Utah job with University of Utah, Department of Nutrition & Integrative Physiology | 12844064The Department of Nutrition and Integrated Physiology (NUIP) at the University of Utah seeks a Tenure Track faculty member at the rank of Assistant... 02327
Reposted by Gina DeNicolaŞuayb Üstün @suaybuestuen.bsky.social · 22/08/2025Job alert 📣 Our faculty looks for a Junior Professor W1 with tt to W2 in Membrane Biology! We are looking for #ECRs working on membrane biogenesis,contact sites,composition & other aspects of membranes in 🌱 and other organisms! DM me if you need more details! jobs.ruhr-uni-bochum.de/jobposting/f...jobs.ruhr-uni-bochum.deW1TTW2 Professorship in Membrane Biology (m/f/d) 13460
Reposted by Gina DeNicolaSoni Lacefield @lacefieldlab.bsky.social · 27/08/2025My department at Dartmouth Medical School is hiring a tenure-track Assistant Professor. We are looking broadly for a biochemist or cell biologist. Please share this add! apply.interfolio.com/171438 @dartmouthbcb.bsky.social @futurepislack.bsky.socialapply.interfolio.com Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio 16777
Reposted by Gina DeNicolaJohanna Joyce @johannajoyce.bsky.social · 21/08/2025A wonderful new opportunity - for both Rising Stars and established Research Leaders - to open a research lab in Ireland 🇮🇪🧪 Up to 3.25 million euro in support 🤩 #GlobalTalentIreland #Research #Ireland 086
Reposted by Gina DeNicolaKarolinska Institutet @ki.se · 18/08/2025Final call: Applications close September 2! KI is recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential. All positions: ki.se/en/about-ki/... 05056
Reposted by Gina DeNicolaKatsu Funai @katsufunai.bsky.social · 21/07/2025We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share! @uofunuip.bsky.socialjobs.sciencecareers.orgOpen Rank, Tenure Track Position – Metabolic Physiology - Salt Lake City, Utah job with University of Utah | 674355The Department of Nutrition and Integrated Physiology (NUIP) at the University of Utah seeks a Tenure Track faculty member at the rank of Assistant... 02932
Gina DeNicola @ginadenicola.bsky.social · 12/08/2025Join us in at Moffitt! The Metabolism Program is recruiting at the Assistant Member (Assistant Professor) level. Review of applications starts September 1st. Please share! Details here: moffitt-cancer-center-careers.hctsportals.com/jobs/1883440...moffitt-cancer-center-careers.hctsportals.comTenure-Earning Assistant Member Metabolism & Physiology Faculty in Tampa, FL - Moffitt Cancer Center CareersTenure-Earning Assistant Member Metabolism & Physiology Faculty in Tampa, FL - Moffitt Cance...Working at Moffitt Cancer Center is both a career and a mission. All employees are dedicated to patient care, research and education to advance our fight against this disease. 076
Reposted by Gina DeNicolaBrent Stockwell @brentstockwell.bsky.social · 31/07/2025Thanks to James Olzmann and Scott Dixon for organizing a fantastic #faseb #ferroptosis meeting in Scottsdale AZ! Lots of great science as ferroptosis continues to impact diverse biology and diseases. Can’t wait for the next one! @olzmannlab.bsky.social 1289
Gina DeNicola @ginadenicola.bsky.social · 27/07/2025Hot science and hot temperatures at the FASEB Ferroptosis conference start tonight. Seriously the highs are 110F here 🥵 but it's beautiful! 0141
Reposted by Gina DeNicolaMara Sherman @marasherman.bsky.social · 24/07/2025To distract from your own stress responses (!!!), check out this awesome new study from the Commisso lab linking metabolic stress to regulation of the pancreatic tumor microenvironment! ✨ 092
Reposted by Gina DeNicolaElizabeth McKenna @elizsmckenna.bsky.social · 22/07/2025It's my first #newPI roll call on BlueSky! Calling all new #cancer PIs who just started or who are about to start their labs! Please say hi and what you work on so I can follow you if I don't already! 😃 02711
Reposted by Gina DeNicolaJeremy Berg @jeremymberg.bsky.social · 12/07/2025IMPORTANT IMPORTANT IMPORTANT IMPORTANT Please watch the workshop video and COMMENT by 5:00 Monday 7/14 This is the source of the "no more model organism only grants in NIH-funded research" decree. 4103115
Reposted by Gina DeNicolabioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 10/06/2025FRA1 drives melanoma metastasis through an actionable transcriptional network www.biorxiv.org/content/10.1101/202… 011
Reposted by Gina DeNicolaChristian Frezza @frezzalab.bsky.social · 21/05/2025Unravelling cysteine-deficiency-associated rapid weight loss www.nature.com/articles/s41...nature.comUnravelling cysteine-deficiency-associated rapid weight loss - NatureConditional cysteine restriction in mice causes substantial weight loss, exceeding that seen with essential amino acid restriction, by activating the integrated stress and oxidative stress respon... 0155
Reposted by Gina DeNicolaJeremy Berg @jeremymberg.bsky.social · 20/05/2025REMINDER.....REMINDER......REMINDER 3 DAYS LEFT TO COMMENT ON SCHEDULE F 1/nmedia.tenor.comgumball and anais from the amazing world of gumball are sitting at a tableALT: gumball and anais from the amazing world of gumball are sitting at a table 38886
Reposted by Gina DeNicolaJournal of Cell Science @jcellsci.bsky.social · 20/05/2025Our latest ‘Cell Scientist to Watch’ is Samantha Lewis. We caught up with Samantha to discuss her career path, the challenges for working on the ‘neglected’ mitochondrial genome and the exciting new frontiers in mitochondrial research. journals.biologists.com/jcs/article/... #JCSMitoSI 092
Gina DeNicola @ginadenicola.bsky.social · 12/05/2025MALDI imaging of lipids, metabolites and glycans all on the same section! From Ramon Sun and colleagues. www.nature.com/articles/s41...nature.comSpatial mapping of the brain metabolome lipidome and glycome - Nature CommunicationsClarke et al. presents a framework for spatial analysis of the metabolome, lipidome, and glycome from a single tissue section using mass spectrometry imaging. Applying this approach, they revealed reg... 0204
Reposted by Gina DeNicolaJournal of Cell Science @jcellsci.bsky.social · 09/05/2025In their Tools & Resources article, Corey Cunningham @cnfxc.bsky.social Jared Rutter @rutterlab.bsky.social @uofubiochem.bsky.social & team present their dual-purification system to isolate mitochondrial subpopulations. journals.biologists.com/jcs/article/... #JCSMitoSI #OpenAccess #Mitochondria 031
Gina DeNicola @ginadenicola.bsky.social · 08/05/2025🚨New paper alert! Led by former undergrad Amanda Sherwood @tophinogenesis.bsky.social (now PhD student at Northwestern), Amanda asked whether the glutathione or thioredoxin systems are necessary for NRF2's tumor-promoting effects in the lung. www.sciencedirect.com/science/arti...sciencedirect.comDistinct roles for the thioredoxin and glutathione antioxidant systems in Nrf2-Mediated lung tumor initiation and progressionRedox regulators are emerging as critical mediators of lung tumorigenesis. NRF2 and its negative regulator KEAP1 are commonly mutated in human lung ca… 193
Gina DeNicola @ginadenicola.bsky.social · 06/05/2025That's a wrap on the 2025 Cancer Metabolism Showcase. With everything going on it was so great to hear a fantastic career keynote from Jeff Rathmell and awesome talks and posters from students and postdocs! Hats off to @harrislab.bsky.social for running the show. 2173
Reposted by Gina DeNicolaJames Olzmann @olzmannlab.bsky.social · 03/05/2025Reminder: The 1st FASEB #Ferroptosis Meeting is this summer! Spectacular speaker lineup + short talks selected from submitted abstracts. It is going to be awesome! Trainees, newcomers & all interested are welcome! 📅 Abstract deadline: June 1, 2025. shorturl.at/QA6T1 0238
Reposted by Gina DeNicolaDavid MacPherson Lab @davidmacphersonlab.bsky.social · 29/04/2025Our latest, in Science Advances: In vivo CRISPR screen revealed sgRNAs that switch chemosensitive SCLC PDXs to become resistant.We validated KEAP1 as key hit and found KEAP1 alterations in IMpower133 trial, where active NRF2 links to reduced survival in chemo arm www.science.org/doi/10.1126/... 1/2 1186
Reposted by Gina DeNicolaAaron Quinlan (he/him) @aaronquinlan.bsky.social · 28/04/2025The Department of Human Genetics at the University of Utah is sponsoring the Rising Stars in Genetics and Genomics symposium! - We are seeking nominations bu June 1. - September 18-19, 2025 - Please share with the star postdocs that you know. docs.google.com/forms/d/e/1F... 15543
Reposted by Gina DeNicolaFASEB @faseborg.bsky.social · 25/04/2025#FOLSCR is a new conference exploring all aspects of a form of cell death that results from iron accumulation and lipid peroxidation. Hear keynotes @ginadenicola.bsky.social and @brentstockwell.bsky.social with organizers Scott Dixon and @olzmannlab.bsky.social. Save your space: buff.ly/MmJsYQq 055
Reposted by Gina DeNicolaJeremy Berg @jeremymberg.bsky.social · 23/04/2025 ACTION ITEM-----ACTION ITEM Implementation of Schedule F This is what a lot of us have been worried about. This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs. BUT THERE IS A COMMENT PERIOD... 1/nmedia.tenor.comthe word alert is in a purple circleALT: the word alert is in a purple circle 17362446
Reposted by Gina DeNicolaChristian Frezza @frezzalab.bsky.social · 10/04/2025Targeted tumor therapy with L-cyst(e)ine-addicted bacteria-nanodrug biohybrids: Cell Metabolism www.cell.com/cell-metabol...cell.comTargeted tumor therapy with L-cyst(e)ine-addicted bacteria-nanodrug biohybridsWang et al. advance bacteria-based metabolic therapy by developing DL@SFEc+ through dual-selection evolution. The evolved SFEc+ significantly enhances CySS uptake and desulfhydrase activity. Combined ... 093
Reposted by Gina DeNicolaEric Topol @erictopol.bsky.social · 03/04/2025Discovery of a gut-joint axis pathway and the salutary role of GLP-1 for "wear and tear" arthritis. New @science.org www.science.org/doi/10.1126/... www.science.org/doi/10.1126/... 1227756
Reposted by Gina DeNicolaLiron Bar-Peled @liron1bar-peled.bsky.social · 26/03/2025I’m excited to share the latest work from our lab, led by a group of three amazing scientists: Junbing Zhang, Yousuf Ali and Harrison Chong, who describe @nature the discovery of a ROS sensor, VPS35, which links cytosolic H2O2 levels to regulation of mitochondrial translation andnature.comOxidation of retromer complex controls mitochondrial translation - NatureSystematic base-editing and computational screens identify specific cysteine residues on VPS35 in the retromer complex as key sensors that decrease mitochondrial translation in response to reactive ox... 45613
Reposted by Gina DeNicolaChristian Frezza @frezzalab.bsky.social · 21/03/2025The time is now: accounting for time-of-day effects to improve reproducibility and translation of metabolism researchhttps:// www.nature.com/articles/s42255-025-01237-6nature.comThe time is now: accounting for time-of-day effects to improve reproducibility and translation of metabolism research - Nature MetabolismThis broad group of authors summarizes the impact of circadian factors on metabolic biology and offers recommendations on how to account for and report biological, environmental and experimental facto... 0185
Reposted by Gina DeNicolaScience Magazine @science.org · 20/03/2025In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion. Learn more in this week's issue: scim.ag/3FA3Ygq 15464144
Gina DeNicola @ginadenicola.bsky.social · 18/03/2025What's better than spatial metabolomics? Spatial metabolomics in 3D! New from Ramon Sun and colleagues, a 3D map of the brain metabolome using AI, with an interactive database to explore. www.nature.com/articles/s42...nature.comAI-driven framework to map the brain metabolome in three dimensions - Nature MetabolismThis study presents MetaVision3D, a pipeline to integrate mass spectrometry imaging sections into 3D reconstructions of metabolomic maps. The authors also provide a comprehensive 3D metabolome atlas o... 1196
Reposted by Gina DeNicolaDeBerardinis Lab at UT Southwestern Medical Center @rjdlab.bsky.social · 15/03/20251/Happy to share a new paper reporting a metabolic approach to radiosensitization in lung cancer, from Rachel Chiang, Faith Zhang and colleagues at UT Southwestern Radiation Oncology and @cri-utsw.bsky.social www.science.org/doi/10.1126/...science.orgLipoylation inhibition enhances radiation control of lung cancer by suppressing homologous recombination DNA damage repairGenetic screen finds lipoylation as a target to improve radiation success in lung cancer by blocking DNA damage repair. 35822
Gina DeNicola @ginadenicola.bsky.social · 11/03/2025Fascinating work from MALDI master Ramon Sun and collaborators on glycogen metabolism in NSCLC. A real tour de force and such beautiful images 😍 www.nature.com/articles/s42...nature.comGlycogen drives tumour initiation and progression in lung adenocarcinoma - Nature MetabolismClarke, Hawkinson and colleagues study the contribution of glycogen accumulation in the onset and progression of lung cancer. 0257
