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Brent Stockwell

@brentstockwell.bsky.social
1.1K followers 188 following 39 posts

Chair, Dept of Biological Sciences, Columbia University. Metabolism; cell death; ferroptosis; lipids; chemical biology; cancer; neurodegeneration; spatial biology; drug discovery; AI

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Brent Stockwell @brentstockwell.bsky.social · 02/07/2026
EXO Chat w/ Prof. Norbert Perrimon (Harvard/HHMI) and 1st author Dr. Myeonghoon Han, from his lab, about their EXO review on deorphanizing the secretome: where biochemistry, genetics, and AI meet. www.sciexplor.com/exo/podcast/3
sciexplor.com
EXO - Beyond the Cell | Science Exploration Press
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Brent Stockwell @brentstockwell.bsky.social · 04/06/2026
Excited to see our second podcast out!
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Brent Stockwell @brentstockwell.bsky.social · 16/05/2026
Honored to visit UT MD Anderson to receive the Mike Hogg Award. The highlights were the ceremony and the conversations with researchers there, especially around their passion for #ferroptosis and new ideas about #cancertherapeutics. Few places combine depth of resources with that caliber of people.
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Brent Stockwell @brentstockwell.bsky.social · 10/04/2026
Congrats to co-authors Jenny Jin, Jiachen Hu, Mingyue Li, Wei Gu, and Xuejun Jiang on publication of our new review on #ferroptosis as an approach to leverage #cancer #metabolism in Trends in Cell Biology! It is freely available: authors.elsevier.com/sd/article/S...
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Brent Stockwell @brentstockwell.bsky.social · 01/04/2026
honored to deliver the William E.M. Lands Lecture. Dr. Lands’ pioneering work on the Lands cycle and PL remodeling continues to shape how we think about lipid biology, #ferroptosis and its roles in health and disease. Thank you U of Michigan for the warm welcome and good luck in the Final Four!!
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Brent Stockwell @brentstockwell.bsky.social · 25/01/2026
Here is reading for this snowy day: Congrats to Hanna Feinsod on publication of our perspective in Ferroptosis & Oxidative Stress on 3 major unanswered questions in #ferroptosis! www.sciexplor.com/articles/fos...
sciexplor.com
Fundamental mechanism of ferroptosis: Three unanswered questions
Ferroptosis, an iron-dependent form of regulated cell death (RCD) driven by lipid peroxidation, has been extensively studied since its conceptualization in 2012 and has been suggested as a therapeutic...
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Brent Stockwell @brentstockwell.bsky.social · 03/01/2026
The Columbia Dept of Biological Sciences is searching for an #Assistant #Professor with expertise in #Biochemistry. please apply and spread the word! https:// apply.interfolio.com/179345
apply.interfolio.com
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Brent Stockwell @brentstockwell.bsky.social · 15/11/2025
Congrats to Ed Reznik and the team on our paper "Lipidomic changes in persister cancer cells drive enhanced ferroptosis sensitivity" in the new journal Ferroptosis and Oxidative Stress! www.sciexplor.com/articles/fos... (free w/ no subscription no APCs)
sciexplor.com
Lipidomic changes in persister cancer cells drive enhanced ferroptosis sensitivity
Aims: Unique in the broader category of drug-resistant cells, persister cancer cells (PSs) acquire their tolerance to compounds through reversible, chromatin-mediated changes, allowing them to ‘persis...
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Brent Stockwell @brentstockwell.bsky.social · 29/10/2025
Professor King understood that impactful researchers can benefit broader society by teaching about their #science, and that education is improved when we bring frontier research ideas in the classroom.
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Brent Stockwell @brentstockwell.bsky.social · 29/10/2025
I was honored to give the L. Carroll King Memorial Lectures at Northwestern University, sponsored by the Chemistry Department. Professor King was a pioneering researcher and #teacher who joined Northwestern’s faculty in 1942. He was active in advancing ideas about chemical #education
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Brent Stockwell @brentstockwell.bsky.social · 20/10/2025
I’m excited to lead this new journal that will focus on how cells interact with their environment. We are assembling a top tier editorial board, key partnerships, and looking to be the primary forum for the rapidly growing field of spatial biology.
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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 14/10/2025
Congratulations to IICD member @brentstockwell.bsky.social who was awarded an NCI P01 grant with Xuejun Jiang (MSK) and Wei Gu (CUIMC). Read more: cancerdynamics.columbia.edu/news/brent-s... cc: @columbiacancer.bsky.social @mskcancercenter.bsky.social @columbiamed.bsky.social
Brent Stockwell
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Brent Stockwell @brentstockwell.bsky.social · 18/09/2025
Congrats to Jenny and Liam on our Prevew in Molecular Cell on the excellent paper by Yaqin Deng, Jin Ye et al in the same issue describing a new protection mechanism against #ferroptosis by #DHA — Here is a free download: authors.elsevier.com/a/1loAH3vVUP... @MolecularCell @Columbia
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Brent Stockwell @brentstockwell.bsky.social · 31/07/2025
Thanks to James Olzmann and Scott Dixon for organizing a fantastic #faseb #ferroptosis meeting in Scottsdale AZ! Lots of great science as ferroptosis continues to impact diverse biology and diseases. Can’t wait for the next one! @olzmannlab.bsky.social
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Brent Stockwell @brentstockwell.bsky.social · 11/06/2025
Congrats to Tyson Sharp and his colleagues on the bioRxiv paper on LIMD1 loss conferring #GPX4 sensitivity in lung cancer. An important #cancer #ferroptosis study. www.biorxiv.org/content/10.1...
biorxiv.org
LIMD1 Loss Confers a GPX4-Dependent Cell State in Lung Cancer
LIMD1 (LIM domains containing 1) is a bona-fide tumour suppressor gene frequently lost during the early stages of non-small cell lung cancer (NSCLC) development, resulting in a worse outcome for LIMD1...
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Brent Stockwell @brentstockwell.bsky.social · 04/06/2025
It was great fun to be there!
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Brent Stockwell @brentstockwell.bsky.social · 22/05/2025
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Brent Stockwell @brentstockwell.bsky.social · 08/05/2025
Here is our latest paper in @ACSBiol on compounds that restore activity to the R152H GPX4 variant, found in patients with SSMD. Congrats to Hengrui, Farhad and Russ on a great collaboration! @columbia #ferroptosis pubs.acs.org/doi/full/10....
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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 05/05/2025
📢 The May IICD newsletter is live! Highlights include CINner—our new tool in @plos.org by @khanhndinh.bsky.social lab, #CancerResearchMonth spotlights on @brentstockwell.bsky.social & Yue Wang, and recent achievements from our community.🔗 Read the full issue: bit.ly/43fNAe7
IICD May newsletter
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Brent Stockwell @brentstockwell.bsky.social · 04/05/2025
It was a true pleasure to visit such an outstanding group of faculty and students! Can’t wait to see all the great discoveries that will emerge from the #moleculartherapeutics division
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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 01/05/2025
🔬 During #CancerResearchMonth, we’re spotlighting @brentstockwell.bsky.social, exploring ferroptosis as a powerful way to eliminate aggressive cancers. His latest work links diet and cancer treatment: bit.ly/4iNEWc5 @columbiacancer.bsky.social @columbiamed.bsky.social @columbiasysbio.bsky.social
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Brent Stockwell @brentstockwell.bsky.social · 30/04/2025
Looking forward to hosting the first #ferroptosis cancer symposium at #AACR25 in 30 minutes. Join us in person or online!
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FASEB @faseborg.bsky.social · 25/04/2025
#FOLSCR is a new conference exploring all aspects of a form of cell death that results from iron accumulation and lipid peroxidation. Hear keynotes @ginadenicola.bsky.social and @brentstockwell.bsky.social with organizers Scott Dixon and @olzmannlab.bsky.social. Save your space: buff.ly/MmJsYQq
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Brent Stockwell @brentstockwell.bsky.social · 13/03/2025
Congratulations Dean Gonzalez!
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Brent Stockwell @brentstockwell.bsky.social · 08/03/2025
Only 4 days left to register. I hope to see many new ferroptosis researchers in Chicago!
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Brent Stockwell @brentstockwell.bsky.social · 06/03/2025
Final deadline is imminent—last chance to join us in Chicago!
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Brent Stockwell @brentstockwell.bsky.social · 01/03/2025
Only a few days left to register. We are loving the abstracts you are submitting!
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Brent Stockwell @brentstockwell.bsky.social · 01/03/2025
Only a few days left to register. We are loving the abstracts you are submitting!
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Brent Stockwell @brentstockwell.bsky.social · 28/02/2025
Come join us in Chicago!
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Brent Stockwell @brentstockwell.bsky.social · 28/02/2025
Thank you @senkalce.bsky.social for hosting me for a fantastic visit at VCU! What an impressive group of faculty and students doing impactful science
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Brent Stockwell @brentstockwell.bsky.social · 28/02/2025
It was great to meet you @pauladbos.bsky.social and spend time at VCU!
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Brent Stockwell @brentstockwell.bsky.social · 26/02/2025
A few more days left to register!
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Brent Stockwell @brentstockwell.bsky.social · 24/02/2025
We extended the deadline on the #Chicago #ASBMB #Ferroptosis meeting! 12 short talks will be selected from the abstracts. Register for what we expect to be a great conference! www.asbmb.org/meetings-eve...
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Brent Stockwell @brentstockwell.bsky.social · 24/02/2025
We extended the deadline on the #Chicago #ASBMB #Ferroptosis meeting! 12 short talks will be selected from the abstracts. Register for what we expect to be a great conference! www.asbmb.org/meetings-eve...
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Brent Stockwell @brentstockwell.bsky.social · 03/01/2025
Our first paper of #2025! We identified viral-selective, non-covalent inhibitors of #coronavirus #3CL main #protease using a DNA-encoded library, and optimized them using x-ray crystallography. www.nature.com/articles/s41...
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Brent Stockwell @brentstockwell.bsky.social · 28/12/2024
Please apply!
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Brent Stockwell @brentstockwell.bsky.social · 05/12/2024
The Dept. of Biological Sciences at Columbia is searching for an #AssistantProfessor in the area of #biochemistry — submit a one-page anonymized statement of research w/app. Apply here: : apply.interfolio.com/160181
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Brent Stockwell @brentstockwell.bsky.social · 06/12/2024
Yes it is a new idea. We are trying this as an experiment.
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Brent Stockwell @brentstockwell.bsky.social · 06/12/2024
Yes Yale MB&B pioneered this. mbb.yale.edu/news/mbb-com...
mbb.yale.edu
MB&B completes anonymized search for faculty positions | Molecular Biophysics and Biochemistry
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Brent Stockwell @brentstockwell.bsky.social · 05/12/2024
The Dept. of Biological Sciences at Columbia is searching for an #AssistantProfessor in the area of #biochemistry — submit a one-page anonymized statement of research w/app. Apply here: : apply.interfolio.com/160181
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Brent Stockwell @brentstockwell.bsky.social · 04/12/2024
Thank you to Project ALS and Salk for hosting a fantastic meeting on advances in the science of motor neurons leading to new ALS Therapies!
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Keiran Pedley @keiranpedley.bsky.social · 01/12/2024
😂
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Stella Hurtley @smhsci.bsky.social · 29/11/2024
And finally (probably) for today, my choice this week in @science.org @lozanzi.bsky.social 10.1016/j.cell.2024.10.010
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Randall Munroe @xkcd.com · 09/11/2024
Number Shortage xkcd.com/3009
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Angelo D’Alessandro @dalessandrolab.bsky.social · 28/11/2024
I wouldn’t forget about blood transfusion. www.weforum.org/stories/2018...
weforum.org
These discoveries have saved billions of lives
An explosion in 20th Century technologies, treatments, and other science-backed breakthroughs helped to increase global life expectancy at an unprecedented rate.
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James Olzmann @olzmannlab.bsky.social · 24/11/2024
I finally joined! I am a professor at UC Berkeley. My lab is interested in the cell biology and therapeutic targeting of lipid homeostasis: lipid droplets, protein & lipid quality control, lipid damage & ferroptosis, and drug discovery. Here is a pic of our group from our summer lab party. 💙
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Brent Stockwell @brentstockwell.bsky.social · 24/11/2024
Congrats to Columbia Football for winning their first Ivy League title since 1961! @columbia www.columbiaspectator.com/sports/2024/...
columbiaspectator.com
Football clinches first Ivy League title since 1961
After 63 years, football’s conference title drought is over. Columbia took down Cornell on Saturday, clinching a share of the Ivy League title for the first time since 1961. With Yale beating Harvard ...
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Brent Stockwell @brentstockwell.bsky.social · 22/11/2024
Our perspective in Science Magazine on #Ferroptosis—#disease perils and #therapeutic promise www.science.org/doi/10.1126/... written for a general audience -- not too technical. Congrats to authors Ashley Brown and Tal Hirschhorn!
science.org
Ferroptosis—disease perils and therapeutic promise
Mechanisms of iron-dependent cell death reveal potential new targets for disease treatment
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Brent Stockwell @brentstockwell.bsky.social · 19/11/2024
Very pleased to be listed as a highly cited researcher — a testament to a great network of trainees and collaborators and the ever-growing #ferroptosis community! clarivate.com/highly-cited...
clarivate.com
Highly Cited Researchers | Clarivate
The Highly Cited Researchers 2024 list identifies and celebrates individuals who have demonstrated significant and broad influence in their fields of research. Through rigorous selection criteria and ...
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Brent Stockwell @brentstockwell.bsky.social · 18/11/2024
Congrats!
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