The precise mechanism of action of the antibiotic daptomycin is controversial. Here, Buttress et al. provide evidence for two independent antibacterial mechanisms: membrane depolarisation and inhibiti...

Calcium homeostasis is essential for bacterial physiology, yet its regulation and role in specialized processes such as microbially induced calcite precipitation (MICP) and sporulation remain poorly u...

42.1K Views. University of Groningen. This protocol provides a step-by-step procedure to monitor single cell behavior of different bacteria in time using automated fluorescence time-lapse microscopy....

Bacillus subtilis produces surfactin, a powerful detergent-like compound that functions in intercellular communication, surface motility, and as a broad-spectrum antimicrobial agent. Production of surfactin, a cyclic lipopeptide, depends on a non-...

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Patel and Helmann identify metabolic pathways that are dysregulated in RNAP mutant strains with altered β-lactam sensitivity. Genetic and physiological studies demonstrate that BCAA and Pyr synthesis ...

npj Antimicrobials and Resistance - A historical perspective on the multifunctional outer membrane channel protein TolC in Escherichia coli

Three Austrian Universities located in Vienna and Graz combine forces to explore the immunometabolic interaction of macrophages with tissues. We are looking for 6 PhD and 6 postdoctoral researchers jo...

Sphingoid bases, including sphingosine, are important components of the antimicrobial barrier at epithelial surfaces where they can cause growth inhibition and killing of susceptible bacteria. Pseudom...

Duncan lab

Decision to downgrade 271 journals on quality and operating model concerns sparks debate

2024 milestones worth celebrating 🧬🌟 Bravo to the incredible researchers at the Drug Discovery Unit at Newcastle University. They've unlocked a potential…

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