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Huishan Liu

@flymanhuishan.bsky.social
189 followers 458 following 6 posts

I study AM symbiosis in maize

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Reposted by Huishan Liu
Michael Hothorn @structplantbio.bsky.social · 11/09/2026
Nice work by @cellsensing.bsky.social Glycan recognition by a plant damage-sensing immune receptor www.science.org/doi/10.1126/...
science.org
Glycan recognition by a plant damage-sensing immune receptor
Pathogens target and degrade the extracellular matrix surrounding plant cells. A central question is how cell wall-derived damage-associated molecular patterns (DAMPs) are recognized and integrated to...
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Reposted by Huishan Liu
Pingtao Ding (he/him) @dinglab.bsky.social · 10/08/2026
Our work is now online @cp-cellhostmicrobe.bsky.social Congrats to all authors @himanshuchhillar.bsky.social @leonardojo.bsky.social Amey Volkan @kaisakajala.bsky.social @jonathandgjones.bsky.social Supported primarily by the @erc.europa.eu #StG www.cell.com/cell-host-mi... @unileiden.bsky.social
cell.com
Cell-type-specific activation of broadly perceived effector-triggered immunity restricts pathogen invasion in plants
Chhillar et al. reveal that plant immunity is organized across leaf tissues through specialized cell-type programs. While a shared core immune program is broadly activated, individual cell types deplo...
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Margot Smit @likeyoda1.bsky.social · 11/08/2026
Fresh preprint online from our group! We find that stomatal maturation IS possible in the embryo, when they lack ERECTA signaling, but then still, only at the cotyledon tip. A thread. www.biorxiv.org/content/10.6...
biorxiv.org
ERECTA signaling controls the timing of Arabidopsis Guard Cell maturation at the embryonic leaf tip
While cell identities are established early during embryogenesis, these cells remain immature until germination, and the mechanisms enforcing this developmental pause are poorly understood. Embryonic ...
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Gitta Coaker @gittacoaker.bsky.social · 25/07/2026
www.science.org/doi/10.1126/...
science.org
Programmable design of synthetic plant immune receptors for pathogen protein recognition
The limited diversity and recognition scope of natural plant immune receptors impede resistance breeding against rapidly evolving pathogens. Here we report programmable design of synthetic plant immun...
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Sebastian Schornack @dromius.bsky.social · 13/07/2026
Preprint! How do "friendly" rhizobia build a legume nodule? @albinteulet.bsky.social found that some may carry hidden transcription factors - proteins that mimic DNA-binding folds to enter the plant nucleus and rewrite its developmental program. www.biorxiv.org/content/10.6... (1/6)
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cryoEM papers @cryoempapers.bsky.social · 12/07/2026
Privateer for UCSF ChimeraX: Carbohydrate structure validation and visualization pubmed.ncbi.nlm.nih.gov/42427255/ #cryoEM
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yuxuan-xi.bsky.social @yuxuan-xi.bsky.social · 11/07/2026
Our new preprint is out! Using AI-guided design (RFdiffusion + ProteinMPNN), we engineered a plant immune receptor to recognise non-cognate pathogen effectors. Huge thanks to our amazing co-authors for making this possible! doi.org/10.64898/202...
doi.org
Computational design of de novo integrated domains enables rational control of pathogen effector recognition in plant NLR immune receptors.
The rapid evolution of plant pathogens poses a persistent threat to global agricultural sustainability, often outpacing the discovery and deployment of natural disease resistance genes. While bioengin...
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Reposted by Huishan Liu
Alex Churchill @alexchurchill.bsky.social · 24/06/2026
Same dude, same. From the age of 10 the library was my refuge and my safe space
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Sebastián Moreno-Ramírez @sebamorenor.bsky.social · 22/06/2026
Excited to share that our work on single-nucleus RNA-seq of the shoot apical meristem — the shoot stem cell niche — has found a home. #Plantascience #scRNAseq #stemcells www.science.org/doi/10.1126/...
science.org
Single-nucleus transcriptomics resolves multiple fate dynamics between inflorescence meristem and primary stem
snRNA-seq reveals shoot stem cell heterogeneity and traces their differentiation into primary stem cell types.
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Lena Maria Müller @lmueller.bsky.social · 10/06/2026
Amazing collaboration with the Bowman lab. FLIM reveals hidden layers of plant-AMF interactions!
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Bruno Ngou @brunongou.bsky.social · 03/06/2026
Excited to share that I will start my lab this summer as an ECL Unit Leader at RIKEN CSRS! We will study perception by cell-surface receptors across diverse plant species. I’ll be recruiting soon, so please reach out if you’re interested!
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Huishan Liu @flymanhuishan.bsky.social · 12/06/2026
Global density and biomass of arbuscular mycorrhizal fungal networks www.science.org/doi/10.1126/...
science.org
Global density and biomass of arbuscular mycorrhizal fungal networks
Arbuscular mycorrhizal fungi form symbioses with ~70% of plant species, building hyphal networks that exchange nutrients for host-derived carbon. These tubular networks move ~1 billion metric tons of ...
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Huishan Liu @flymanhuishan.bsky.social · 11/06/2026
Glycan recognition by a plant sentinel immune receptor www.biorxiv.org/content/10.1...
biorxiv.org
Glycan recognition by a plant sentinel immune receptor
Pathogens target and degrade the extracellular matrix surrounding plant cells. A central question is how cell wall–derived damage-associated molecular patterns (DAMPs) are recognized and integrated to...
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Reposted by Huishan Liu
Anne Knowlton @anneknowlton.bsky.social · 08/06/2026
Our beautiful special issue on plant evolution is out @currentbiology.bsky.social ! www.cell.com/issue/S0960-...
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Jeffrey Ross-Ibarra @jrossibarra.bsky.social · 07/06/2026
got my concluding slide on challenges with estimating ancestral recombination graphs ready for PEQG
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Travis Lee @tralee-sci.bsky.social · 22/05/2026
How do cells break symmetry to generate new shape and form? Using the apical hook as a model, we @joeecker.bsky.social applied spatial and single-cell multiomics, and identify a regulatory hotspot in a transient cell niche that drives this U-shaped structure 1/8 bsky.app/profile/bior...
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Jeffrey Ross-Ibarra @jrossibarra.bsky.social · 18/05/2026
I got excited and posted but should clarify. While we figured out the oak was a clone and likely really old, the conservation win is thanks to years of effort by a whole bunch of other folks. Attending meetings, organizing, filing lawsuits, and plain old not giving up.
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Nature @nature.com · 29/07/2025
Nature research paper: Integrated biotechnological and AI innovations for crop improvement go.nature.com/44LN6NJ
go.nature.com
Integrated biotechnological and AI innovations for crop improvement - Nature
The integration of omics technologies, genome editing and protein design with artificial intelligence (AI) promises rapid advances in the field of crop improvement that will improve global food security.
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Hiro Nakagami @grandpahiro.bsky.social · 28/04/2026
New layer of plant immune system "membrane mechanosensing immunity (MSI), a third layer of cell surface immune signaling" is nicely demonstrated by @julien-gronnier.bsky.social group Cool finding! Congratulations!
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Justin Walley @justinwwalley.bsky.social · 07/05/2026
Our latest review on Single Cell Proteomics is out. Honored that it is a Feature Review in the @cp-trendsbiochem.bsky.social special series: TIBS at 50 - Foundations and Frontiers. #Proteomics www.sciencedirect.com/science/arti...
sciencedirect.com
Mass spectrometry-based single-cell proteomics technologies, trends, and biological insights
Single-cell proteomics (SCP) has emerged as a transformative approach for characterizing cellular heterogeneity at the protein level. Recent advances …
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Jae Young Choi @jychoi.bsky.social · 30/04/2026
I'm looking to hire a postdoc. Please share if you can!
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Nitzan Shabek @shabeklab.bsky.social · 22/04/2026
🔥our latest study is now online @natcomms.nature.com we found that the salicylic acid catabolic enzymes DMR6/DLO1 are controlled by the ubiquitin system. SA modulates their turnover, revealing a regulatory circuit linking hormone metabolism to immune balance. www.nature.com/articles/s41...
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Gitta Coaker @gittacoaker.bsky.social · 18/04/2026
We are hiring! We’re excited to recruit a postdoc to our lab at UC Davis to work on plant immune engineering and single-cell analyses of plant pathogen interactions. Apply by June 1. Please repost. www.coakerlab.org/postdoctoral...
Postdoctoral Scholar position in the Coaker group
University of California, Davis
We are seeking a Postdoctoral Scholar to join our research program focused on immune receptor engineering and spatial analyses of plant pathogens interactions using computational and imaging approaches. The position will involve integration of molecular, imaging, and computational approaches. Relevant publications from the laboratory include Nature Plants (2025, PMID: 40721669), Proceedings of the National Academy of Sciences (2024, PMID: 38814867), and Cell Reports (2023, PMID: 37342910). https://www.coakerlab.org/
Qualifications:
•	Ph.D. in plant biology, molecular biology, genetics, computational biology, or a related field
•	Strong background in genomics and/or computational biology 
•	First author publications in peer-reviewed journals
•	Ability to work both independently and collaboratively in a multidisciplinary environment
•	Experience in plant innate immunity is preferred

Application Instructions:
The position is initially available for two years, with the possibility of extension based on performance and funding. Salary is based on the University of California postdoctoral salary scale (https://www.ucop.edu/academic-personnel-programs/_files/2025-26/represented-oct-2025-scales/t23.pdf). The salary range for this position is $69,073-$82,836 US Dollars/year. 
Review of applications will begin June 1, 2026 and will continue until the position is filled.
Please submit a CV, a brief statement of research interests (~1 page), and contact information for three references to glcoaker@ucdavis.edu. The research statement should describe your previous work, how your expertise aligns with ongoing research in the lab, and potential future research directions.
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MSU Plant Resilience Institute @msupri.bsky.social · 06/04/2026
The Topp lab is recruiting multiple postdoctoral researchers across complementary areas of root biology, phenomics, and translational crop science! Learn more about the postdoc opportunities and apply now: plantresilience.msu.edu/team/join.as... #PlantScience #PlantSciJobs
The graphic is a job advertisement for postdoctoral researcher positions in the Topp lab. It features a faded background image of a plant root on top of a ruler next to a probe with the Plant Resilience Institute logo in the top left corner. In the middle of the graphic is a green gradient arrow with the following text: “Now Hiring: Topp Lab Postdoctoral Researchers." In the bottom right corner, there is the MSU PRI logo and the text: “Apply online at careers.msu.edu.”
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Marc Somssich @somssich.bsky.social · 09/11/2023
📜 Single-cell analysis identifies genes facilitating rhizobium infection in Lotus japonicus 🧑‍🔬 Manuel Frank, Lavinia Ioana Fechete, Dugald Reid, Stig Uggerhøj Andersen, et al. 📔 Nature Communications 🔗 www.nature.com/articles/s41... #️⃣ (Feeds) #PlantScience #Symbiosis #PlantMPMI #LotusJaponicus
nature.com
Single-cell analysis identifies genes facilitating rhizobium infection in Lotus japonicus - Nature C...
The authors use single-cell analysis to identify genes specifically expressed in plant root cells that respond to infection by nitrogen-fixing rhizobia. They show that one of these genes, SYMRKL1, is ...
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Huishan Liu @flymanhuishan.bsky.social · 15/04/2026
RHD6LA regulates root hair responses to both symbionts and commensals www.nature.com/articles/s41...
nature.com
RHD6LA regulates root hair responses to both symbionts and commensals - Nature Communications
Single cell RNA-seq shows that commensal bacteria activate a Nod factor-independent program in legume root hairs overlapping with rhizobial signaling. RHD6LA facilitates infection thread formation and...
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Reposted by Huishan Liu
Gitta Coaker @gittacoaker.bsky.social · 18/03/2026
www.nature.com/articles/s41...
nature.com
The paradox of immune systems conservation between prokaryotes and eukaryotes - Nature Reviews Microbiology
The widespread prokaryotic immune systems, in particular restriction–modification, CRISPR–Cas and defensive toxin–antitoxin systems, are absent in eukaryotes, whereas relatively rare ones, such as Arg...
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Huishan Liu @flymanhuishan.bsky.social · 23/01/2026
Structural basis for size-selective perception of chitin in plants www.biorxiv.org/content/10.1...
biorxiv.org
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Prof Peter Hotez MD PhD DSc(hon) @peterhotezmdphd.bsky.social · 13/04/2025
My latest in @plosbiology.org Look I get it, it seems really dark, but there are opportunities. My paper explores some ideas and tries to guide ways of thinking through the anticipated challenges. An emphasis on America’s “biohubs” and entrepreneurship journals.plos.org/plosbiology/...
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Adam Mott @adammott.bsky.social · 06/11/2025
Cool new paper on receptor specificity. www.nature.com/articles/s41...
nature.com
Two residues reprogram immunity receptors for nitrogen-fixing symbiosis - Nature
An investigation of plant receptor-like kinases identifies regions of these proteins that control whether immune or symbiotic signalling pathways are activated, with minimal changes to specific r...
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MaizeGDB @maizegdb.bsky.social · 13/06/2025
New data from the Bob Schmitz lab (Marand 2025) on cell type-specific cis-regulation in maize! This study, in @science.org, reveals how DNA changes impact expression and maize traits. Explore the 176 new tracks on the browser under Epigenetics and DNA binding. ➡️ www.science.org/doi/10.1126/...
science.org
The genetic architecture of cell type–specific cis regulation in maize
Gene expression and complex phenotypes are determined by the activity of cis-regulatory elements. However, an understanding of how extant genetic variants affect cis regulation remains limited. Here, ...
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Current Biology @currentbiology.bsky.social · 12/06/2025
The scope of #fungi #biodiversity is only beginning to be fathomed. Every day almost ten new species are described. 🍄🤯 David Hibbett László Nagy and Henrik Nilsson introduce the fungal tree of life. www.cell.com/current-biol...
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Vasilis Kokkoris @vkokkoris.bsky.social · 10/06/2025
📢Our synthesis of current knowledge on the fascinating cell of #arbuscular #mycorrhizal fungi is out @currentbiology.bsky.social, part of the special #fungi issue. With @rachaelcargill.bsky.social @tobykiers.bsky.social @thomasshimizu.bsky.social Open access link: www.cell.com/current-biol... 1/4
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 10/06/2025
90% of you probably don’t need to read this. But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy. It’s about sharing something hard to say out loud; partly to heal, partly in case someone needs to hear it too. (1/3) tinyurl.com/DudinO
cell.com
Omaya Dudin
Interview with Omaya Dudin, who uses Ichthyosporea as models to study how and why unicellular organisms evolved multicellularity at the University of Geneva.
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Sebastian S. Cocioba @atinygreencell.bsky.social · 02/05/2025
I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs. Plant, Bacterial, Archaeal Non-model Bioeng Custom Lab Hardware Turn Key Genetic Design Please repost for reach 💚
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Plant Direct Journal @plantdirectj.bsky.social · 26/03/2025
Genomic Markers Associated With Soybean Resistance to the Stem Borer, Dectes texanus (Coleoptera: Cerambycidae) (Sarah Johnson, David Hyten) doi.org/10.1002/pld3... #PlantScience
doi.org
Manhattan plots for (A) larvae and (B) girdled stems from 379 accessions analyzed for the GWAS analysis. Green line is the Bonferroni correction at p = 0.01, and the red dashed line is at p = 0.05.
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New Scientist @newscientist.com · 31/03/2025
Welcome to the era of "vibe coding", where people are using ChatGPT and other AI tools to help write code, even if they don't know anything about software.
newscientist.com
What is vibe coding, should you be doing it, and does it matter?
The rise of large language models like ChatGPT that can churn out computer code has led to a new term - vibe coding - for people who create software by asking AI to do it for them
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Nicholas Provart @bar-plantbio.bsky.social · 21/03/2025
Want to travel to Portland, Maine and present at the Gordon Research Conference on Single-Cell Approaches in Plant Biology? Short talk submissions are open until April 30, 2025. All other applications for this conference are due July 13th. To apply: bit.ly/ApplyforGRC (submit as a poster abstract)
bit.ly
2025 Single-Cell Approaches in Plant Biology Conference GRC
The 2025 Gordon Research Conference on Single-Cell Approaches in Plant Biology will be held in Portland, Maine. Apply today to reserve your spot.
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Nigel Goldenfeld @nigelgoldenfeld.bsky.social · 28/02/2025
🧪 Wonderful to see UCSD Academic Senate Chair Olivia Graeve encouraging the entire campus to #standupforscience at the rally next Fri March 7 2025 at 12 noon in front of the Geisel Library/Silent Tree! Stand up for science ... and all scholarship at universities. @standupforscience.bsky.social
UCSD Academic Senate Chair Olivia Graeve encouraging the entire campus to #standupforscience at the rally next Fri March 7 2025 at 12 noon in front of the Geisel Library/Silent Tree!
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Huishan Liu @flymanhuishan.bsky.social · 02/03/2025
podcasts.apple.com/us/podcast/t...
podcasts.apple.com
Clinical update with Dr. Daniel Griffin
Podcast Episode · This Week in Virology · 03/01/2025 · 59m
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Katie Hinde @mammalssuck.bsky.social · 18/02/2025
I escaped poverty because I am a scientist. And I am a scientist because of the National Science Foundation. A 🧵:
A Lady Professor with brown hair and glasses, wearing a scarf in red, green, yellow, & black, a gift from an incredible lactation  consultant, sitting in in front of cactus.
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Kara Swisher @karaswisher.bsky.social · 19/02/2025
Math is hard
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Fred Hutch @fredhutch.org · 13/02/2025
Researchers at Fred Hutch have discovered an overlooked mechanism driving aggressive breast and brain tumors involving genes so ancient — more than 2 billion years old — that they fly under the radar of standard genetic sequencing methods. 1/9 www.science.org/doi/10.1126/...
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Huishan Liu @flymanhuishan.bsky.social · 17/02/2025
Latent activity in TnpB revealed by mutational scanning www.biorxiv.org/content/10.1...
biorxiv.org
Latent activity in TnpB revealed by mutational scanning
TnpB is an evolutionarily diverse family of RNA-guided endonucleases associated with prokaryotic transposons. Due to their small size and putative evolutionary relationship to Cas12s, TnpB holds signi...
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Kate Starbird @katestarbird.bsky.social · 13/02/2025
With both RFK Jr and Gabbard confirmed, two people who rose to prominence spreading conspiracy theories about public health and national intelligence will now run the U.S. government agencies in charge of those areas. For someone studying these conspiracy theories for a decade... this is nauseating.
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Ben Stone @benstemon.bsky.social · 30/01/2025
It’s official: all funding requests made on Tuesday by postdocs for their salaries have been unilaterally rejected by NSF.
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Monique Smith @moeneuro.bsky.social · 19/01/2025
It is Faculty interview season, so I created a doc with compiled Chalk Talk advice! Please share widely- this shouldn't be hidden curriculum... there is a recipe for success! I will also share videos of my practice and actual UCSD chalk talk with anyone who wants it! DM me!
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Yasin Dagdas @plantophagy.bsky.social · 15/01/2025
This is a truly awesome story by @priyaramakrishna.bsky.social & @nikogeldner.bsky.social et al. #CryoSEM imaging of elements!!! They just opened the floodgates for many many cool discoveries!!! www.nature.com/articles/s41...
nature.com
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation - Nature
This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elemen...
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The CapituLab @thecapitulab.bsky.social · 09/01/2025
CapituLab capitula take #4 - lettuce flowers are (maybe surprisingly) among our absolute favorites! We are using lettuce in the lab as a genetic model system to study how flowers in the Asteraceae develop. The red ones here were some of the first transformed in lab by @reidselby.bsky.social!
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Jeffrey Ross-Ibarra @jrossibarra.bsky.social · 09/01/2025
Postdoc jobs in the Gaut lab! Brandon isn't on here, so I can be frank: he is fantastic. I did my postdoc with him and he is not only an amazing scientist but one of my favorite humans. I would have happily stayed in his lab forever if that was feasible. recruit.ap.uci.edu/JPF08999 #plantscijobs
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