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yuxuan-xi.bsky.social

@yuxuan-xi.bsky.social
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Yu Sugihara @yusugihara.bsky.social · 08/10/2026
Excited to share our latest work! 🍅 Two evolutionarily distinct immune receptors recognize the same viral target, yet differ in their recognition spectra. A fascinating example of convergent evolution in plant immunity!
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Reposted by @yuxuan-xi.bsky.social
Adam Bentham @adamrbentham.bsky.social · 30/09/2026
🚨 Please share! 🚨 I'm recruiting a fully funded 4-year Gatsby Sainsbury PhD studentship at Durham! 🌱🤖 Designing plant immune receptors from scratch, combining AI protein design with structural biology and plant immunity. If you're interested please get in touch! benthamlab.org shorturl.at/U2PdV
benthamlab.org
Bentham Lab — Durham University
Bentham Lab, Centre for Programmable Biological Matter, Durham University. Structural biology and de novo protein design applied to host-pathogen interactions, plant immunity, and neglected tropical d...
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Reposted by @yuxuan-xi.bsky.social
Sophien Kamoun @kamounlab.bsky.social · 01/09/2026
Among several new members of our team is Yuxuan Xi who joins us from the John Innes Center and the Plant Health Institute of Montpellier (PHIM) in Montpellier. Yuxuan is interested in the interactions between plants and pathogens, notably NLR biology kamounlab.tumblr.com/post/8265465...
kamounlab.tumblr.com
Kamoun Lab @ TSL
Among several new members of our team is Yuxuan Xi who joins us from the John Innes Center and the Plant Health Institute of Montpellier (PHIM) in Montpellier. Yuxuan is interested in the interactions...
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Reposted by @yuxuan-xi.bsky.social
Josh Bennett @joshwbennett.bsky.social · 07/08/2026
I am really excited to share the first chapter of my PhD, where we characterise a genetically linked NLR/MLKL pair underpinning the Rwt3 resistance locus in wheat! With yet another KFP involved in monocot immunity 🌾 www.biorxiv.org/content/10.6...
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Reposted by @yuxuan-xi.bsky.social
Adam Bentham @adamrbentham.bsky.social · 24/07/2026
This is very cool and a phenomenal amount of work! Great to see protein design shaping the future of disease resistance bioengineering. We now really have entered the era of truly bespoke resistance! www.science.org/doi/10.1126/...
science.org
Programmable design of synthetic plant immune receptors for pathogen protein recognition
The limited diversity and recognition scope of natural plant immune receptors impede resistance breeding against rapidly evolving pathogens. Here we report programmable design of synthetic plant immun...
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Reposted by @yuxuan-xi.bsky.social
Adam Bentham @adamrbentham.bsky.social · 13/07/2026
Excited to see our new preprint on bioRxiv! 🌱🤖 We used AI protein design (RFdiffusion + ProteinMPNN) to build brand-new sensor domains from scratch and installed them in a rice NLR immune receptor engineering recognition of a Fusarium effector FoSSP17
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yuxuan-xi.bsky.social @yuxuan-xi.bsky.social · 11/07/2026
Our new preprint is out! Using AI-guided design (RFdiffusion + ProteinMPNN), we engineered a plant immune receptor to recognise non-cognate pathogen effectors. Huge thanks to our amazing co-authors for making this possible! doi.org/10.64898/202...
doi.org
Computational design of de novo integrated domains enables rational control of pathogen effector recognition in plant NLR immune receptors.
The rapid evolution of plant pathogens poses a persistent threat to global agricultural sustainability, often outpacing the discovery and deployment of natural disease resistance genes. While bioengin...
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