Nature Reviews Genetics, Published online: 08 September 2026; doi:10.1038/s41576-026-01004-7Programmed DNA elimination is a developmentally regulated process in which specific DNA sequences are reproducibly removed from particular cell lineages. Here, the authors review the mechanistic diversity and evolutionary dynamics of DNA elimination, spanning chromosome breakage, whole-chromosome elimination and whole-genome elimination.

Abstract. Toxin-antitoxin systems (TAs) are widespread in bacterial genomes. Yet, their integration, persistence, and impact in chromosome dynamics remain

Department of Genetics at Rutgers University

Winner of the Vilcek Prize for Creative Promise, Akera’s novel research findings have huge implications for infertility and chromosomal disorders.

Optogenetic manipulation of spindle dynamics reveals that microtubule shortening at kinetochores limits spindle elongation rather than moving chromosomes, revealing local chromosome–spindle interactio...

Abstract. Biological individuality exists in different forms—unicellular, multicellular, colonial, etc.—which have arisen through evolutionary transitions

Abstract. Meiotic drivers are selfish genetic elements that gain transmission advantages by distorting equal, Mendelian segregation. For decades, biologist

Abstract. Meiotic drivers are selfish genetic elements that are predicted to spark rapid intra-genomic arms races with their suppressors. However, the long

"The only constant in life is change." — Heraclitus Genetic conflicts — the good, the bad, and the ugly — shape our lives over time We aim to understand why even the most essential genes and chrom...

Leading evolutionary theorists and philosophers come together to understand how organisms persist, even as they’re riddled with internal conflict, from cancer cells to selfish genes.How does a vast me...

This unparalleled collection includes Rosalind Franklin's historic 'Photo 51,' which revealed the double-helix structure of DNA.

The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades.

Cells require highly polymorphic receptors to perform accurate self/non-self recognition. In the amoeba Dicytostelium discoideum, polymorphic TgrB1 & TgrC1 proteins are used to bind sister cells and e...

Episode 4 is out. In season 2, we focus on the transition from postdoc to PI, highlighting the unique challenges faced by postdocs and early-career PIs worldwide. Hosted by the Lonely Pipette.

Identify long STRs, VNTRs, satellite DNA and other low-complexity regions in a genome - lh3/longdust

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Request for Information: Use of Cloud Resources and New File Formats for Sequence Read Archive Data NOT-OD-20-108. NIH

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Abstract. Satellite DNAs (satDNAs), ubiquitous sequences in eukaryotic genomes, play a crucial role in genome organization, function, and evolution. The pe