Diploid genome assemblies are now routinely available, but most read aligners were designed for haploid references, which have long been the gold standard. When reads are aligned to a diploid assembly...

Successor of bwa-mem for short-read alignment. Contribute to lh3/minibwa development by creating an account on GitHub.

Pure-Rust BAM/SAM/CRAM/FASTA reader, pileup engine, and VCF/BCF writer.

Successful Job Applications and Grants. Contribute to RILAB/statements development by creating an account on GitHub.

Recently, Heng Li released MiniBWA (GitHub) alongside a paper by Heng Li and Nils Homer describing the method (paper). MiniBWA builds on the approaches in Minimap2 (also by Heng Li), but falls back on...

Heng Li and Nils Homer revisit BWA-MEM with a faster mapper for short reads, accurate long reads, and bisulfite sequencing data.

Notable changes: New feature: added the mem subcommand to mimic the bwa-mem command-line interface (CLI). Most input/output options and commonly used options are retained; unsupported or incompat...

This release fixed several minor bugs: Bugfix: FASTA comments not parsed correctly during indexing (#22). It is recommended to reindex the reference genome with the new release. Bugfix: double ...

Russell Vought is going destroy American Science

Abstract. Population-scale long-read DNA sequencing (PLRS) is rapidly reshaping our understanding of genomic variation in humans and non-model species. In

Nature Methods - In this study, long-read RNA sequencing achieves accurate single-nucleotide polymorphism calling, haplotype phasing and allele-specific expression analysis.

Nature Biotechnology - A long-read metagenome assembly method recovers circular and complete genomes better than existing tools.

A long-read metagenome assembly method recovers circular and complete genomes better than existing tools.

Matematiska institutionen består av cirka 120 forskare, lärare och administrativ personal och är organiserad i tre huvudsakliga avdelningar: Matematik, Matematisk statistik och Beräkningsmatematik

Long-read sequencing data is useful for detecting large and complex structural variations; however, technical artifacts can lead to false structural variant calls. In our analyses, we became aware of ...

MENLO PARK, Calif., Feb. 02, 2026 (GLOBE NEWSWIRE) — PacBio (NASDAQ: PACB), a leading developer of high-quality, highly accurate sequencing solutions, today announced the completion of the sale of sel...

Amplicon sequencing variants from 16s ONT R10.4 / HiFi long reads - bluenote-1577/savont

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A collection of high-quality human genomes. Contribute to lh3/human-asm development by creating an account on GitHub.