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Toby Baril

@tobybarilbio.bsky.social
651 followers 977 following 98 posts

Incoming Group Leader @ NRM 🇸🇪 | genome-ecology.com | Transposable Elements, Evolution, Machine Learning | #openscience | #FirstGen | 🇬🇧🇫🇷 | Ski | Bike | Climb | Join TEsky: bsky.app/profile/did:plc:mw4y54k2y4…

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Reposted by Toby Baril
Saba Mottaghinia @mottasx1.bsky.social · 31/08/2026
2 years & 8 new Myotis bat genomes later, so proud to be an alum of these incredible teams showing how bats break the rules: adapting to DNA viruses using exact same pathways behind their cancer resistance & long lifespans. Bats are evolutionarily economical & this makes them so cool! #TEworldwide
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Toby Baril @tobybarilbio.bsky.social · 28/08/2026
#TEsky #TEworldwide
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Toby Baril @tobybarilbio.bsky.social · 25/08/2026
#TEsky #TEworldwide
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Arvid Ågren @arvidagren.bsky.social · 18/08/2026
New paper with Nick Davies and Kevin Foster in @natcomms.nature.com. We show that often neither selection against transposons’ deleterious effects nor exploitation by parasitic elements is sufficient to keep them in control. Only active host suppression does. www.nature.com/articles/s41...
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Gulnara Tagirdzhanova @metalichen.bsky.social · 11/08/2026
Our study on giant transposons Starship 🚀🧬 in the genome of the lichen fungus Xanthoria is now out in @pnas.org! What did we find out about Starships in #lichen fungi? 👇Updated thread below 🖥️ 🧪 🦠 🧫 #SymbioSky 1/6 www.pnas.org/doi/10.1073/...
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Toby Baril @tobybarilbio.bsky.social · 12/08/2026
Thrilled to share that I'll be starting my lab at the Swedish Museum of Natural History in Stockholm as a DDLS Fellow in November! 🧑‍🔬🧬🎉 Of course, we will be delving into all things mobile DNA & evolution, as well as developing AI approaches for biodiversity genomics #newPI #TEsky #TEworldwide
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Yann Bourgeois @bourgeoisyann.bsky.social · 07/08/2026
A first attempt at deep learning, ABC, and moments to estimate parameters about the pop dynamics of transposons. I will soon post a post-doc offer to work on TEs in palms, and I hope these resources may be helpful. Feel free to comment. I need feedback. yannbourgeois.github.io/projects/1_p...
yannbourgeois.github.io
Population dynamics of Transposable Elements | Yann X.C. Bourgeois
Ongoing project
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Toby Baril @tobybarilbio.bsky.social · 27/07/2026
EarlGrey ParTEA v0.2.0 is out! Pangenome TE annotation across multiple genomes just got a major upgrade — now fully compatible with RepeatMasker 4.2.4, RepeatModeler 2.0.9, RMBlast 2.17, and Dfam 4.0 / FamDB 3.0.0 🧬 🔗 github.com/TobyBaril/EarlGreyParTEA #TEworldwide #TEsky #genomics #transposons
github.com
GitHub - TobyBaril/EarlGreyParTEA: 2+ genomes make a parTEA! This pangenome TE annotation pipeline extends EarlGrey for multi-genome comparative analysis
2+ genomes make a parTEA! This pangenome TE annotation pipeline extends EarlGrey for multi-genome comparative analysis - TobyBaril/EarlGreyParTEA
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Toby Baril @tobybarilbio.bsky.social · 24/07/2026
Huge congrats to @alicelaigle.bsky.social for driving this work - excited to share this preprint! Comparative analyses reveal rapid turnover and emergence of transitory 3D genome architectures in the fungal kingdom www.biorxiv.org/content/10.6... #fungi #bioinformatics #evolution #preprint
biorxiv.org
Comparative analyses reveal rapid turnover and emergence of transitory 3D genome architectures in the fungal kingdom
The three-dimensional architecture of genomes plays major roles in biological processes such as gene expression and DNA replication. The architecture of genomes has evolved substantially with distinct...
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Reposted by Toby Baril
Rebecca Berrens @rberrens.bsky.social · 10/07/2026
Hi #TEsky, please remember that we have an amazing community in the TransposonsWorldWide slack channel (join.slack.com/t/transposon...), which I encourage you to join. Another great resource is tehub.org. Please share !
join.slack.com
Join TransposonsWorldwide on Slack
Slack is a new way to communicate with your team. It’s faster, better organized, and more secure than email.
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Toby Baril @tobybarilbio.bsky.social · 26/06/2026
This is huge! Very excited to hear this great news!
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Travis Wheeler @wheelerlab.org · 26/06/2026
An exciting day for TE research and open science. #tesky
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Nozhat @nozhathassan.bsky.social · 26/06/2026
Congratulations to the authors (and my friends), @alex-stuart.bsky.social and Chandler on their paper on CR1 retrotransposons across vertebrates! And thanks for letting me tag along! #TEsky academic.oup.com/gbe/advance-...
academic.oup.com
Ancient persistence and newfound diversity of CR1-group retrotransposons across vertebrates
Abstract. Retrotransposons are mobile, repetitive DNA sequences that are ubiquitous across eukaryotes and widely recognised as key drivers of both gene and
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Toby Baril @tobybarilbio.bsky.social · 22/06/2026
#TEsky #TEworldwide
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Cedric Feschotte @cedricfeschotte.bsky.social · 29/05/2026
📣 POSTDOC position available in the Feschotte Lab at Cornell to work on #TRANSPOSONS! More details below. Pls send informal application or inquiry ASAP by DM or email to cf458_at_cornell.edu. Pls spread the word 🙏 #TEsky www.thefeschottelabatcornell.com
thefeschottelabatcornell.com
The Feschotte Lab at Cornell
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Toby Baril @tobybarilbio.bsky.social · 18/06/2026
#TEsky #TEworldwide
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Toby Baril @tobybarilbio.bsky.social · 17/06/2026
Really great to see this preprint out! Amazing effort by @camillecornet.bsky.social, and a privilege to have been involved in this one, thanks for beginning me back to butterflies, Camille! 😉 #TEsky #TEworldwide #Genomics #Bioinformatics #Chromosome #Evolution #Butterflies
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Etienne Bucher 🌾🧬🇪🇺 @plantepigenetics.ch · 05/06/2026
We just published our new paper about an active Helitron transposon in wheat 🌾🧬 We found that it can be mobilised by heat stress when DNA methylation is reduced. We document its full lifecycle: RNA -> circular DNA -> integration www.nature.com/articles/s41... #TEsky
nature.com
An active Helitron transposon family in wheat - Nature Plants
Helitrons are a recently identified category of transposons. This study reveals that heat stress combined with reduced DNA methylation can mobilize a Helitron family in wheat. Its mobilization is gene...
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Alice Godden @alicegodden.bsky.social · 28/05/2026
Looking for small pot of funding approx £5,000 to conduct some exciting genomics for a pilot transposons and climate resilience project in vulnerable species. If anyone knows of any pots available to UK-based researchers please let me know :) #funding #research #academia #NERC #UKRI
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Toby Baril @tobybarilbio.bsky.social · 20/05/2026
Population-level structural variant characterization using pangenome graphs www.nature.com/articles/s41...
nature.com
Population-level structural variant characterization using pangenome graphs - Nature Genetics
Swave is a method to call structural variants from pangenome graphs using a recurrent neural network to identify structural variant patterns, including complex structural variants.
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Toby Baril @tobybarilbio.bsky.social · 09/04/2026
🎉 EarlGrey ParTEA v0.1.6 is here! Huge thanks to everyone who's tried the pipeline and shared feedback — your suggestions directly shaped these new features. 🍵 #TEworldwide #transposableelements #bioinformatics #genomics
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Toby Baril @tobybarilbio.bsky.social · 17/03/2026
🎉🧬 Multiple genomes/pangenome? Time for a parTEA! 🧬 ☕️ Tired of annotating TEs one genome at a time? Same. So we organised a parTEA! Introducing EarlGrey ParTEA v0.1.3 — consistent TE annotation across all your genomes, in parallel, with one command: github.com/TobyBaril/Ea... #TEworldwide #TEsky
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Rebecca Berrens @rberrens.bsky.social · 12/03/2026
We are looking for a Postdoc to join our lab at @oxfordbiochemistry.bsky.social. This is a dry-lab focused post on the computational analysis of long read single-cell sequencing data to understand the role of transposable elements (TEs) in early development. my.corehr.com/pls/uoxrecru... #TEsky
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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Toby Baril @tobybarilbio.bsky.social · 09/03/2026
Had a great chat with Sophie about this work back in Heidelberg, excited to dive into this preprint! #TEsky #TEworldwide
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Dr. Tyler A. Elliott @transposableman.bsky.social · 06/03/2026
#TEsky a short paper from @mbonar.bsky.social , myself and others on our reannotation of TEs in the Octopus vulgaris genome. More work to come using genome ecology to analyze TEs in this species bsky.app/profile/bior...
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Toby Baril @tobybarilbio.bsky.social · 05/03/2026
#TEworldwide #TEsky
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Toby Baril @tobybarilbio.bsky.social · 05/03/2026
Need to annotate transposons in fungal genomes? 🧬 Good news #MycoMobilome is now live! Check it out here: doi.org/10.1093/narg... Access the sequences through our Zenodo community (you can also contribute seqs with credit), and synchronisation with @dfam.bsky.social! w/ @danielcroll.bsky.social
doi.org
MycoMobilome: a community-focused non-redundant database of transposable element consensus sequences for the fungal kingdom
Abstract. Transposable elements (TEs) are found in nearly all eukaryotic genomes. Despite significant advances in the sequencing of genomes, TE resources r
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Reposted by Toby Baril
Dr. Tyler A. Elliott @transposableman.bsky.social · 30/01/2026
#TEsky EDTA-GUI: a plant-optimized graphical implementation of the EDTA pipeline enabling lineage-level classification and analysis doi.org/10.1186/s128...
doi.org
EDTA-GUI: a plant-optimized graphical implementation of the EDTA pipeline enabling lineage-level classification and analysis - BMC Genomics
BMC Genomics - Transposable elements (TEs) are major components of plant genomes, shaping genome architecture, gene regulation, and evolutionary innovation. While the Extensive de novo TE Annotator...
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Toby Baril @tobybarilbio.bsky.social · 22/01/2026
Blinded by the lights? Re-examining the adaptive role of transposable elements in plants with population genomics #TEworldwide #TEsky www.sciencedirect.com/science/arti...
sciencedirect.com
Blinded by the lights? Re-examining the adaptive role of transposable elements in plants with population genomics
Transposable elements (TEs) are ubiquitous components of the genome whose mobility can be triggered by environmental stress and influenced by genotype…
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Reposted by Toby Baril
Alice Laigle @alicelaigle.bsky.social · 20/01/2026
👏 Congratulations Toby for this Current Biology dispatch! 🎨 Happy to see my watercolours in it to illustrate this so-cool topic! #illustration #sciart #scicomm #TE #fungi #watercolours #TEworldwide
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Jason Nomburg @jnoms.bsky.social · 08/01/2026
I'm recruiting 1-2 grad students through the AITHYRA-CeMM PhD program! Applications are due January 30th. This is a fully-funded PhD program, combining AI and biology to advance biological discovery. Please forward to anyone who may be interested! You can apply here: apply.cemm.at
apply.cemm.at
Fullfabric :: AITHYRA-CeMM PhD
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Toby Baril @tobybarilbio.bsky.social · 19/01/2026
🍄Transposon traffic in the mycocosmos🍄 Fascinating work reveals extensive horizontal TE transfer across fungi (@jromeijn.bsky.social, Iñigo Bañales & @mfseidl.bsky.social; doi.org/10.1016/j.cu...). I wrote a Dispatch to prime non-specialists,check it out here: doi.org/10.1016/j.cu.... #TEworldwide
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Toby Baril @tobybarilbio.bsky.social · 05/01/2026
#TEworldwide
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Toby Baril @tobybarilbio.bsky.social · 05/01/2026
#TEsky #TEworldwide #Transposons #Bioinformatics #Bioconda #GenomeAnnotation #TransposableElements #Genomics #ComparativeGenomics
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Toby Baril @tobybarilbio.bsky.social · 05/01/2026
☕Earl Grey v7.0.0 brewed fresh☕ Nested TEs finally get the treatment they deserve: iterative detection of deep nesting, cleaner GFF annotations, and coverage stats that don’t double-count genomic space + a RepeatCraft edge-case fix. Happy new year to the TE folks! 🧬 github.com/TobyBaril/Ea...
github.com
GitHub - TobyBaril/EarlGrey: Earl Grey: A fully automated TE curation and annotation pipeline
Earl Grey: A fully automated TE curation and annotation pipeline - TobyBaril/EarlGrey
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Waggoner Lab @labwaggoner.bsky.social · 10/12/2025
Transposable elements can insert into genes, disrupting protein-coding potential. Researchers discover a mode of RNA processing, ‘SOS splicing’, that provides a quick fix @nature.com @harvardmed.bsky.social www.nature.com/articles/d41... www.nature.com/articles/s41...
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Toby Baril @tobybarilbio.bsky.social · 12/11/2025
TEs aren’t just genomic parasites, they’re also engines of genomic novelty. Our new study with ~2,000 Z. tritici genomes shows repeated TE mobilization waves during global expansion. With @danielcroll.bsky.social & @guidopuccetti.bsky.social 🧬 www.nature.com/articles/s41... #TEworldwide
nature.com
Historic transposon mobilisation waves create distinct pools of adaptive variants in a major crop pathogen - Nature Communications
In this study, the authors analysed a large genomic dataset to trace how jumping genes shaped the global spread of a major wheat pathogen and reveal bursts of activity over decades that drove adaptati...
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sandraduharcourt.bsky.social @sandraduharcourt.bsky.social · 10/11/2025
Excited to share our new preprint on BioRxiv! A collaborative effort spanning many years and several labs to uncover what the germline chromosomes of Paramecium really look like. 🔗 www.biorxiv.org/content/10.1... 1/5
biorxiv.org
The tiny germline chromosomes of Paramecium aurelia have an exceptionally high recombination rate and are capped by a new class of Helitrons
Background. Paramecia belong to the ciliate phylum of unicellular eukaryotes characterized by nuclear dimorphism. A diploid germline micronucleus (MIC) transmits genetic information across sexual gene...
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Dr. Tyler A. Elliott @transposableman.bsky.social · 06/11/2025
#TEsky A comparative analysis of transposable element diversity and evolution across 75 bee genomes doi.org/10.1186/s128...
doi.org
A comparative analysis of transposable element diversity and evolution across 75 bee genomes - BMC Genomics
Transposable elements (TEs) are repetitive DNA sequences that can alter their position and abundance within genomes. While TEs are known to have various impacts on genome structure and function, our u...
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Toby Baril @tobybarilbio.bsky.social · 06/11/2025
High-Quality Genome Assembly of Diplocarpon coronariae Unveils LTR Retrotransposon-Driven Structural Dynamics in Fungi Evolution doi.org/10.1111/1755... #TEworldwide #TEsky
doi.org
High‐Quality Genome Assembly of Diplocarpon coronariae Unveils LTR Retrotransposon‐Driven Structural Dynamics in Fungi Evolution
Long terminal repeat retrotransposons (LTR-RTs) are recognised as a significant evolutionary force capable of shaping the structure and function of the genomes in eukaryotes, including animals, plant...
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Toby Baril @tobybarilbio.bsky.social · 06/11/2025
Awesome talk @orpsf.bsky.social! Excited to see what comes next! #TEworldwide #TESky
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Dr. Tyler A. Elliott @transposableman.bsky.social · 05/11/2025
#TEsky Evolution of Mutator transposons in the genomes of worms doi.org/10.1016/j.ge...
doi.org
Redirecting
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EMBL Events @events.embl.org · 04/11/2025
☕ Coffee break time at #EMBOMobileGenome! Inspiring talks, lively discussions, and plenty of caffeine to keep the ideas flowing. The sun’s out, the conversations are buzzing, and tonight we’ll keep the networking going with rooftop lounge drinks 🍂🍁 Looking forward to an exciting week ahead! 🧬
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Toby Baril @tobybarilbio.bsky.social · 05/11/2025
At @embo.org #EMBOMobileGenome and want to connect with other TE researchers and follow the latest goings on? Use #TEworldwide and #TEsky in your posts to be featured in the TEworldwide feed, which you can also find here: bsky.app/profile/did:...
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Toby Baril @tobybarilbio.bsky.social · 04/11/2025
#TEworldwide #TEsky
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Toby Baril @tobybarilbio.bsky.social · 04/11/2025
Time to kick off #EMBOMobileGenome for 2025! A great selection of speakers and posters on the agenda! #TEWorldwide #TESky
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Human Pangenome Reference Consortium @humanpangenome.bsky.social · 29/10/2025
Transposable elements (TEs) do more than regulate genes; they help shape and preserve 3D genome structure across species. Uncover the science behind it: pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov
Co-opted transposons help perpetuate conserved higher-order chromosomal structures
Transposable elements (TEs) make up half of mammalian genomes and shape genome regulation by harboring binding sites for regulatory factors. These include binding sites for architectural proteins, such as CTCF, RAD21, and SMC3, that are involved in ...
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Daniel Croll @danielcroll.bsky.social · 29/10/2025
@tobybarilbio.bsky.social and I are very excited to release MycoMobilome! A very extensive effort to discover, QC and annotate TEs across the fungal kingdom. 👉 Ready-to-use for your own genome with a simple tutorial! 👉 Metadata about TEs discovered in your genome! 👉 Contribute and get recognition!
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Toby Baril @tobybarilbio.bsky.social · 29/10/2025
1/ Ever needed to annotate TEs in a fungal genome, but didn't know where to start? We have released #MycoMobilome, a community-focused non-redundant database of transposable element consensus sequences for the fungal kingdom, constructed from >4,000 fungal genomes! www.biorxiv.org/content/10.1...
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