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Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺

@ettema.bsky.social
1.3K followers 623 following 44 posts

Professor of Microbiology @ WUR 🇳🇱 | Evolutionary microbiology | Exploring the Tree of Life | Archaea aficionado | Symbiotic interactions | husband, father, cat-person, eternal house renovator, secretly a Jedi knight

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Reposted by Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺
Nancy Moran @nancy-moran.bsky.social · 02/07/2026
A step forward in discovering Buchnera's key to the aphid's heart, published today! Thanks to Jerry Maeda and other authors--a great team -- and to the helpful reviewers #SymbioSky doi: doi.org/10.1038/s415...
doi.org
A secreted endosymbiont protein essential for colonizing host cells - Nature
SyeA was present in the Buchnera ancestor, is secreted into the host cytoplasm, is homologous to secreted effectors of bacterial pathogens and is essential for Buchnera transmission.
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Michael Okun @michael-okun.bsky.social · 10/06/2026
I’ve officially resigned as Associate Editor for Frontiers in Systems Neuroscience. It used to be a reputable journal, but became a case study in how forced automation destroys academic integrity. 👇
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Daniel Tamarit @danieltamarit.bsky.social · 22/05/2026
I'm looking for an enthusiastic student to join my team as a PhD candidate on archaeal genome evolution 🦠💻 Work in beautiful Utrecht, at @binfutrecht.bsky.social, an international group full of caring, amazing scientists, and with frequent cake breaks! www.uu.nl/en/organisat... Please share! 🙏
uu.nl
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Molecular Biology and Evolution @molbioevol.bsky.social · 27/05/2026
@joshnhamm.bsky.social @ndombrowski.bsky.social @greening.bsky.social @luisvalentin.bsky.social et al. provide the first investigation into the enigmatic Terrarchaeota and insights into the evolution of high salt adaptation in Archaea. 🔗 doi.org/10.1093/molbev/msag091 #evobio #molbio #microbeSky
doi.org
New lineages provide insights into the convergent evolution of extreme salt adaptation within symbiotic Archaea
Abstract. Environmental genomics has led to the discovery of many new lineages of archaea, including “DPANN” (or Nanobdellati), comprising organisms with s
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Fabien Burki @fburki.bsky.social · 26/05/2026
If you want to read a cool story today, look no further: A billion-year-old bacterial machinery replicates plastid DNA and supports kleptoplastidy #protistsonsky www.biorxiv.org/content/10.6...
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Mark Hamill @markhamillofficial.bsky.social · 16/05/2026
You're entitled to your own opinion. You're NOT entitled to your own facts. #BelieveTheScience What he said 💯 👇 👇 👇
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Microbiology Society @microbiologysociety.org · 05/03/2026
#OnThisDay in 1938, American evolutionary biologist Lynn Margulis was born. Margulis is most known for developing and popularising the endosymbiotic theory, which explains how eukaryotic cells evolved organelles from simpler prokaryotic organisms that resided within another and became incorporated.
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Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺 @ettema.bsky.social · 05/03/2026
Read our review about the "Diversity, ecology, cell biology and evolution of the Asgard archaea" in @natrevmicro.nature.com here: www.nature.com/articles/s41... By @kassipan.bsky.social @stephkoe.bsky.social @micropat.bsky.social & @gerbenz.bsky.social
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Stephan Köstlbacher @stephkoe.bsky.social · 05/03/2026
🧵 1/10 New paper out in @natmicrobiol.nature.com from my postdoc at @mib-wur.bsky.social! 🎉 How eukaryote-like was the archaeal ancestor of eukaryotes? Sequence searches alone can't tell us — so we used protein structure prediction to look deeper. 🧬 www.nature.com/articles/s41...
nature.com
Prediction of eukaryotic cellular complexity in Asgard archaea using structural modelling - Nature Microbiology
A structural catalogue of the Asgard archaeal pangenome reveals hundreds of eukaryotic-like proteins that suggest a higher degree of cellular complexity in the archaeal ancestor of eukaryotes.
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Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺 @ettema.bsky.social · 05/03/2026
Finally out in @natmicrobiol.nature.com: Prediction of eukaryotic cellular complexity in Asgard archaea using structural modelling. Great work by @stephkoe.bsky.social @kassipan.bsky.social @jvhooff.bsky.social www.nature.com/articles/s41...
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Andrew Roger @andrewjroger.bsky.social · 23/02/2026
Have a novel protist's genome or transcriptome and want to predict it's mitochondrial proteome? Look no further than CoMR, this handy bioinformatic workflow to help you: www.biorxiv.org/content/10.6... #phylogenetics
biorxiv.org
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Claus Wilke @clauswilke.com · 13/02/2026
AI agent goes nuts on open source maintainer after having its pull request denied. This is a pretty insane story. Open source development as we've been used to for the last few decades is likely over. 1/ theshamblog.com/an-ai-agent-...
theshamblog.com
An AI Agent Published a Hit Piece on Me
Summary: An AI agent of unknown ownership autonomously wrote and published a personalized hit piece about me after I rejected its code, attempting to damage my reputation and shame me into acceptin…
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The EMBO Journal @embojournal.org · 18/02/2026
Read how @embopress.org is expanding its focus on molecular ecology and evolution as central underpinnings of functions/interactions/diversification of biological systems – by @yehumoran.bsky.social, @berndpulverer.bsky.social, and our new team of Editorial Advisors link.springer.com/article/10.1...
link.springer.com
EMBO Press co-evolves with molecular ecology and evolutionary biology - The EMBO Journal
The EMBO Journal - Molecular ecology and evolution are central to understanding how biological systems function, interact, and diversify. A special issue of this journal reflects the growing...
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WeRateDogs @weratedogs.com · 18/02/2026
This local Wolfdog joined an Olympic ski event and triggered the finish-line camera. This is Nazgul. He snuck into a cross-country skiing sprint this morning and raced the homestretch with some competitors before being escorted home. 14/10 someone get him a medal
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Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺 @ettema.bsky.social · 18/02/2026
Finally out in @nature.com: a new piece of the puzzle of how complex life evolved. Lead by @archaeal.bsky.social & @katyappler.bsky.social. Great collab with @greening.bsky.social and @kassipan.bsky.social. More pieces to follow soon! www.nature.com/articles/s41...
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Courtney Stairs @cstairs.bsky.social · 16/02/2026
Abstract deadline of February 27 is quickly approaching. Registration for the meeting is limited to 120 partipants with presenters (poster or talk) being given priority. So submit an abstract to secure your spot! comparativegenomics2026.com All inclusive registration (hotel+3 meals)
comparativegenomics2026.com
CGUE 2026 – Comparative Genomics of Unicellular Eukaryotes 2026. San Feliu, Spain. 5-10 October
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Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺 @ettema.bsky.social · 16/02/2026
Our latest preprint: Together with the team of Jan Löwe, @danieltamarit.bsky.social and many others we discovered and characterized several Asgard tubulin genes and propose that microtubule architecture and dynamics evolved in Asgard archaea prior to eukaryogenesis www.biorxiv.org/content/10.6...
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Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺 @ettema.bsky.social · 16/02/2026
Hamer + Spijker. Tijd voor verandering van de PhD stelsel op Nederlandse Universiteiten. Lees dit opiniestuk van @erikvansebille.bsky.social in het Digitaal Universiteitsblad van @utrechtuniversity.bsky.social
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Hassan Salem @hassansalem.bsky.social · 16/02/2026
How specific are heritable symbioses? And what can we learn from swapping obligate symbionts across host species? We address this in our latest, led by @inespons.bsky.social & in our collaboration w/ @microbiome.bsky.social 🦠🪲 Out today in @natcomms.nature.com! 1/n www.nature.com/articles/s41...
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Sur Herrera Paredes @surh.bsky.social · 11/02/2026
I'm happy to share our new review with @lau-co89.bsky.social @liigh-unam.bsky.social just published in @genomebiolevol.bsky.social Recent microbial evolutionary insights from metagenomics academic.oup.com/gbe/advance-... Inspired by the session "Molecular evolution through metagenomics" at #SMBE24
academic.oup.com
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Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺 @ettema.bsky.social · 12/02/2026
Two more weeks to apply - come join us () in The Netherlands as a postdoctoral researcher on large-scale metagenomic exploration of new lineages!
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Theo Sanderson @theo.io · 08/02/2026
I made a map of 3.4 million Bluesky users - see if you can find yourself! bluesky-map.theo.io I've seen some similar projects, but IMO this seems to better capture some of the fine-grained detail
bluesky-map.theo.io
Bluesky Map
Interactive map of 3.4 million Bluesky users, visualised by their follower pattern.
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Piotr Lukasik @sympiotr.bsky.social · 11/02/2026
Our new paper in @natcomms.nature.com is now online-early! We describe independent evolution of bacterial genomes of only ~50–52 kb — the smallest known outside cellular organelles — revealing striking convergence toward minimal gene sets. 🔗 doi.org/10.1038/s414...
The visualization of two bacterial genomes, of 50 and 52kb, representing independent instances of extreme genomic reduction in ancient heritable endosymbionts of planthoppers.
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Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺 @ettema.bsky.social · 11/02/2026
Today we published a Correction on our 2023 @nature.com paper reporting the heimdallarchaeial ancestry of eukaryotes: www.nature.com/articles/s41... Corrected paper: www.nature.com/articles/s41... Importantly, the re-analyses of the corrected dataset are consistent with the original findings.
nature.com
Author Correction: Inference and reconstruction of the heimdallarchaeial ancestry of eukaryotes - Nature
Nature - Author Correction: Inference and reconstruction of the heimdallarchaeial ancestry of eukaryotes
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Dolf Weijers @dolfweijers.bsky.social · 28/01/2026
www.wur.nl/en/vacancy/f... Become our new colleague (and next door neighbor) and lead a chair/group/department of Biophysics at Wageningen University. Reach out to me for info and please spread!!!
wur.nl
Full Professor and Chair Laboratory of Biophysics
We are looking for a Full Professor in the Biophysics chair group, part of Wageningen University & Research (WUR)
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Lars Eicholt @lacholt.bsky.social · 28/01/2026
Check out our new review in Nature Reviews Genetics on de novo emerged genes and proteins. How they emerge, are lost and persist - and how de novo emerged proteins relate to randomized proteins! @bornberglab.bsky.social www.nature.com/articles/s41...
nature.com
Emergence and evolution of protein-coding de novo genes - Nature Reviews Genetics
De novo gene evolution entails the birth of new genes from previously non-coding DNA. In this Review, Bornberg-Bauer and Eicholt overview how protein-coding de novo genes are identified, the mechanist...
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Mario Vallejo-Marin @nicrodemo.bsky.social · 28/01/2026
Join us at the Evolutionary Biology Centre at Uppsala University. We’re searching for an Assistant Professor in Biology. www.uu.se/en/about-uu/...
Uppsala in late autumn
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Johannes Hohlbein @hohlbeinlab.bsky.social · 27/01/2026
The Laboratory of Biophysics at Wageningen University & Research (NL) is looking for a new chair! Details here: www.wur.nl/en/vacancy/f...
wur.nl
Full Professor and Chair Laboratory of Biophysics
We are looking for a Full Professor in the Biophysics chair group, part of Wageningen University & Research (WUR)
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EMBL @embl.org · 22/01/2026
EMBL is deeply saddened by the passing of our Interim Director General Peer Bork, a pioneering scientist who left an indelible imprint on life science research in Europe and beyond. We extend our deepest condolences to his family, friends, and colleagues. www.embl.org/news/people-...
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Segata Lab @cibiocm.bsky.social · 21/01/2026
🥁 NEW Our study on infant gut microbiome and #straintransmission is now published in @nature.com: doi.org/10.1038/s415... 1/10
doi.org
Baby-to-baby strain transmission shapes the developing gut microbiome - Nature
A metagenomic survey of babies attending the first year of nursery detected extensive baby-to-baby microbial strain transmission, pointing to social interactions in infancy as crucial drivers of infan...
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Cameron Thrash @jcamthrash.bsky.social · 22/01/2026
Our latest. Led by the very talented @ahoiching.bsky.social Cell cycle dysregulation of globally important SAR11 bacteria resulting from environmental perturbation www.nature.com/articles/s41... #jcampubs 🌊
nature.com
Cell cycle dysregulation of globally important SAR11 bacteria resulting from environmental perturbation - Nature Microbiology
Without key cell cycle control genes, SAR11 cells experience aneuploidy and growth inhibition when exposed to changes in nutrients, carbon sources or temperature stress, a vulnerability that may repre...
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EMBO @embo.org · 17/01/2026
We mourn the passing of Peer Bork, EMBO Member since 2000: www.embl.org/news/embl-announcement…
embl.org
In remembrance of Peer Bork  | EMBL
EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General. 
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Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺 @ettema.bsky.social · 05/01/2026
I have a postdoc position in metagenomic exploration available in my group. Candidates with documented experience in phylo & metagenomics and preferably with petabase-scale data mining and GLM workflows are encouraged to apply. Come join us! 🧬🦠💻 Please repost Apply here: www.wur.nl/en/vacancy/p...
wur.nl
Postdoctoral researcher Phylogenomics and metagenomics
Are you just as excited as we are about the fascinating world of microorganisms? Do you want to contribute to exploring and genomically characterize novel prokaryotic lineages? Do you have a PhD degre...
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Fabien Burki @fburki.bsky.social · 18/12/2025
Just on time for the holidays! Happy to share the published version of the discovery of leptophytes, a new deep-branching and widespread group of microalgae based on plastid MAGs (ptMAGs). Now with additional support from a mitochondrial MAG (mtMAG) of leptophytes. www.nature.com/articles/s41...
nature.com
Identification of a deep-branching lineage of algae using environmental plastid genomes - Nature Communications
Here, the authors leverage data from the Tara Oceans expeditions to perform a phylogeny-guided plastid genome-resolved metagenomic survey and provide 660 non-redundant plastid genomes from marine alga...
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Quanta Magazine @quantamagazine.org · 30/11/2025
A newly discovered archaeal cell has a tiny genome and can’t metabolize biomolecules. It’s upending biologists’ definition of a living thing. “These types of organisms have been found before, but not as extreme as this,” said microbiologist Thijs Ettema.
quantamagazine.org
A Cell So Minimal That It Challenges Definitions of Life | Quanta Magazine
The newly described microbe represents a world of parasitic, intercellular biodiversity only beginning to be revealed by genome sequencing.
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Pedro Beltrao @pedrobeltrao.bsky.social · 28/11/2025
ERC Plus Grants • No career limit, current ERCs are not eligible • Major challenge, transformative research • Up to 7 million euros, up to 7 years • 30 grants per year, 2 years, only once per lifetime • Same application format, plus vision statement • Deadline in September 2026, 2 stage evaluation
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H. B. Beryl Rappaport @hbrappap.bsky.social · 25/11/2025
So happy to announce our new preprint, “A geothermal amoeba sets a new upper temperature limit for eukaryotes.” We cultured a novel amoeba from Lassen Volcanic NP (CA, USA) that divides at 63°C (145°F) 🔥 - a new record for euk growth! #protistsonsky 🧵
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Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺 @ettema.bsky.social · 26/11/2025
Come join us! Soon I will be advertising a postdoc vacancy in my group as part of my @erc.europa.eu AdG project 'DARK ROOTS'. Focus of the project will be on phylo- and metagenomic mining of novel prokaryotic lineages. I will soon post a link here - stay tuned, and please repost! #asgardarchaea
media.tenor.com
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Nico Claassens @nicoc-micsynmet.bsky.social · 25/11/2025
Newest preprint from our lab: a new family of promising synthetic CO2 fixation cycles that may outcompete the Calvin cycle and that Vittorio Rainaldi realized to a great extent in E. coli! Up to 11 heterologous enzymes in a cascade supporting CO2 fixation & growth! www.biorxiv.org/content/10.1...
biorxiv.org
Modular in vivo engineering of the reductive methylaspartate cycles for synthetic CO2 fixation
Biological carbon fixation is currently limited to seven naturally occurring pathways. Synthetic carbon fixation pathways have the potential to surpass aerobic natural pathways in efficiency, but none...
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Joshua Hamm @joshnhamm.bsky.social · 18/11/2025
Ever since publishing our observations of the predatory behaviour of Ca. Nha. antarcticus people have asked me why it would want to kill its host. My perspective discussing the ecological factors that I believe led to this behaviour is out now in mSystems: doi.org/10.1128/msystems.01475-25
doi.org
Nutrient availability affects optimal growth strategy in predatory DPANN | mSystems
The bacterial and archaeal domains each possess a major clade that appears to be predominantly host-associated (1–3). These two lineages, Patescibacteriota and DPANN archaea (named for the Diapherotri...
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Wen-Cong Huang @wentsunghwang.bsky.social · 13/11/2025
#Archaea, #DPANN, #phylogenetic_reconciliation New preprint online! www.biorxiv.org/content/10.1...
biorxiv.org
Phylogenetic reconciliation supports a methanogenic ancestor of the Archaea and a derived origin for host-associated lineages
The phylogeny of the Archaea continues to be revisited and revised as new groups are discovered and phylogenetic methods improve, but key questions about their early evolution remain. It has been sugg...
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Tomer Ullman @tomerullman.bsky.social · 03/11/2025
Nature suggests you use their "Manuscript Adviser" bot to get advice before submitting I uploaded the classic Watson & Crick paper about DNA structure, and the Adviser had this to say about one of the greatest paper endings of the century:
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Fabien Burki @fburki.bsky.social · 12/11/2025
We are looking for a PhD student to work on an exciting plastid endosymbiosis in microbial eukaryotes. This position involves sampling, exciting microscopy such as CARDFISH, ExM and FIBSEM, single-cell transcriptomics and more. #protistsonsky 1/2
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Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺 @ettema.bsky.social · 12/11/2025
Yesterday it was 20 years since I defended my PhD thesis! I have struggled my way through the academic system, with times when I was about to give up due to lack of funding and support. I am proud where I am now, and what I have achieved. Thanks to everyone who supported me and believed in me!
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Mario Vallejo-Marin @nicrodemo.bsky.social · 24/10/2025
Do you want to do a Masters in Evolutionary Biology? The call for applying to the MEME program is now open! MEME is a fantastic 2-year MSc between four European Universities on all areas of Evolutionary Biology. Apply and study in Sweden/France/the Netherlands/Germany/USA/Switzerland! www.evobio.eu
Picture of MEME students on the beach
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Carlos Ribeiro @ribeirocarlitos.bsky.social · 08/10/2025
Interesting how companies and the financial world is racing to spend mindboggling amounts of money to build the infrastructure to train computers. But we are leaving the infrastructure to train and educate humans crumbling. The question is who will train who?
media.tenor.com
a man in a suit is holding a jacket and a cigarette .
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Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺 @ettema.bsky.social · 06/10/2025
OK, somebody should say it: the term 'one-stop-shop' has no place in academic research. Due to their diverse and exploratory nature, there is no single solution for scientific projects - else this would be routine research. RT if you agree, or feel free to argue otherwise below.
media.tenor.com
michael scott from the office is wearing a suit and tie and making a funny face .
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Sonja-Verena Albers @archaellum.bsky.social · 17/09/2025
Happy to share that our story on the bacterial archaellum was published today in @natmicrobiol.nature.com www.nature.com/articles/s41... Congrats to the authors: @sshamphavi.bsky.social @loumollat.bsky.social @mariejoest.bsky.social Najwa Taib and @sgribaldo.bsky.social
nature.com
Structure of a functional archaellum in Bacteria of the Chloroflexota phylum - Nature Microbiology
Bona fide gene clusters for archaella are widespread across a bacterial phylum and encode functional motility machinery.
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Lorenzo Olivi @loreoliv.bsky.social · 22/08/2025
🧵 Our study on the elusive titration control mechanism of the replication initiator DnaA in Escherichia coli is now out on @natcomms.nature.com‬! @stephkoe.bsky.social @hohlbeinlab.bsky.social‬ @nicoc-micsynmet.bsky.social @ettema.bsky.social‬ @mib-wur.bsky.social doi.org/10.1038/s414...
doi.org
The Escherichia coli replication initiator DnaA is titrated on the chromosome - Nature Communications
A DNA-binding protein, DnaA, regulates the initiation of chromosomal replication in bacteria. Here, Olivi et al. show that the bacterial chromosome sequesters DnaA in a growth rate-dependent manner, s...
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ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 15/08/2025
Saddened to learn of the passing of Moselio "Elio" Schaechter—Distinguished Professor at Tufts, SDSU and UCSD—humanist and visionary leader in the fields of microbiology and scientific communication—mentor, friend, and inspiration to me and so many others Small Things Considered Big Things Achieved
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