The emergence of the eukaryotes coincided with the diversification of histone proteins and their post-translational modifications by enzymes that constitute the core of eukaryotic chromatin. Yet the e...

Samples returned from the asteroid Ryugu contain all five canonical nucleobases (A, G, C, T and U). Their presence in Ryugu and Bennu supports the hypothesis that carbonaceous asteroids contributed to the prebiotic chemical inventory of early Earth.

Nature Communications - This study reveals that the malaria parasite Plasmodium uses a unique Aurora kinase complex to control cell division. This divergent machinery regulates spindle formation...

Summary:Akiyoshi, 2025 presented a hypothesis with implications for the early evolution of eukaryotes and eukaryotic cell division machinery. In this Correspondence, the authors conclude that this hyp...

Zijlmans and Stelloo et al. profiled in vivo proximal interactomes of PRC1 and PRC2 in mouse embryonic stem cells, identifying >100 proteins, including transcription factors and RNA-binding proteins. Their findings reveal shared and distinct roles of…

Transmission of genetic material from one generation to the next is a fundamental feature of all liv

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

A systematic characterization of the Polycomb system throughout the eukaryotic tree of life reveals that evolution of PRC1 and PRC2 has been largely uncoupled.