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Direct-current (DC) electric fields are present in all developing and regenerating animal tissues, yet their existence and potential impact on tissue repair and development are largely ignored. This is primarily due to ignorance of the phenomenon by most researchers, some technically poor early studies of the effects of applied fields on cells, and widespread misunderstanding of the fundamental concepts that underlie bioelectricity. This review aims to resolve these issues by describing: 1) the historical context of bioelectricity, 2) the fundamental principles of physics and physiology responsible for DC electric fields within cells and tissues, 3) the cellular mechanisms for the effects of small electric fields on cell behavior, and 4) the clinical potential for electric field treatment of damaged tissues such as epithelia and the nervous system.

Proximity-assisted photoactivation (PAPA) provides a new way to detect protein–protein interactions in single-molecule imaging of live cells.

When cells collide, they often exhibit "contact inhibition of locomotion" (CIL), a behavior in which cells repolarize and migrate away from the site of contact. Experimental CIL outcomes are highly va...

Nuclear magnetic resonance (NMR) spectroscopy is uniquely suited to probing motions on the microsecond to millisecond timescales that underlie RNA rec…

As part of a strategic investment for transformative expansion of Biophysics at Johns Hopkins, the Thomas C. Jenkins Department of Biophysics (https://biophysics.jhu.edu/) invites applications for ten...

The Biophysical Society is seeking the next Editor-in-Chief of the Society’s flagship publication, Biophysical Journal. This appointment will begin January 1, 2027, for one five-year term. The…

Attendees will have the opportunity to present as well as learn from one another. They will give 20-minute talks on their own research questions, as well as in-depth 45-minute whiteboard tutorials on

My five-month quest to monitor the weather, track inflation, and inspect milk for harmful microorganisms

Cells exhibit a mysterious form of selective heritable short-term memory, influencing outcomes as diverse as cell fate decisions in embryos and environmental responses in cancer cells and bacteria. He...

Applications are invited for a University Assistant/Associate Professorship in the broad area of Control Theory and Systems Biology. The successful candidate will join the Control Group

From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...

Millions of researchers could be affected by a “dramatic distortion of citation counts” likely caused by flaws in how the academic publishing giant Springer Nature handles article metadata, accordi…