Despite substantial variation in adult size, animals within a species maintain consistent tissue patterns and shapes, a core property known as developmental scaling or size invariance. Developmental s...

Meiring, Mahapatra et al. show that expanded microtubule lattice conformations, such as those induced by small-molecule taxanes, can lead to the release of GEF-H1 and thus induce RhoA activation.

Department of Developmental NeurobiologyCenter of Excellence for Structural Cell Biology and Neuronal Cell Biology DivisionSt. Jude Children’s Research HospitalThe Center of Excellence for...

Multiple Faculty Positions in Biophysics Theory and Computation at All Levels    Come join JHU Biophysics! The Thomas C. Jenkins Department of Biophysics (https://lnkd.in/eD8NJKgh) invites application...

Epithelial lumen formation is fundamental to organ development, yet how apical surfaces first emerge remains unclear. Ghosh, Martin, and Chen et al., show that lumen initiation is driven via bulk deli...

In cell biology, computational models of biological systems range from minimal representations with a handful of parameters to whole-cell simulations tracking thousands of molecular species across a c...

Cell monolayers are active, orientationally ordered materials whose mechanics can depart from near-equilibrium behavior. Existing continuum theories often inherit assumptions from equilibrium liquid-c...

The mammalian liver possesses a regenerative capacity that is unmatched by any other organ. Following injury, liver epithelial cells can proliferate or even change their identity, enabling the organ t...

A recent preprint by Joseph Hanly and colleagues (Hanly et al., 2026 preprint) investigates the role of a recently identified long non-coding RNA, ivory, and an associated microRNA, mir-193, on wing s...

The endoderm is specified at the onset of gastrulation and subsequently undergoes extensive migration before forming an epithelial sheet that gives rise to multiple organs, including the gut and respi...

The European Commission has today adopted the European Research Council (ERC) Work Programme 2027, setting out the funding opportunities, grant budgets, competition timetable and application rules for...

This Review discusses the complex mechanisms of wound healing — cell migration, matrix remodelling, inflammation and angiogenesis — and the contributions of different cell types, including immune cell...

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

ABSTRACT. C.H. Waddington (1905-1975) was a British biologist and perhaps the major figure in developmental biology between the 1940s and 1960s. He is one of the few pre-molecular-age developmental bi...