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David R. Martinez

@davidmartinez.bsky.social
631 followers 297 following 36 posts

Assistant Professor of Immunobiology and Microbial Pathogenesis at Yale School of Medicine. Hanna H. Gray Faculty Fellow of the HHMI. Scientist. Husband/Dad. Viral pathogenesis. Vaccines. Immunobiology. Above all, be kind.

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Reposted by David R. Martinez
jon ben-menachem @jbenmenachem.com · 21/10/2025
Wow. Harvard nuking its PhD programs - Science PhD admissions reduced by more than 75% - Arts & Humanities reduced by about 60% - Social Sciences by 50–70% - History by 60% - Biology by 75% - The German department will lose all PhD seats - Sociology from six PhD students to zero
thecrimson.com
Harvard FAS Cuts Ph.D. Seats By More Than Half Across Next Two Admissions Cycles | News | The Harvard Crimson
The Faculty of Arts and Sciences slashed the number of Ph.D. student admissions slots for the Science division by more than 75 percent and for the Arts & Humanities division by about 60 percent for th...
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Melody Schreiber @melodyschreiber.com · 16/10/2025
The first locally acquired case of chikungunya in the US since 2019 has been reported on Long Island
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Keystone Symposia @keystonesymposia.bsky.social · 09/10/2025
ICYMI: Our Sept Fellows Spotlight features Dr. David Martinez @davidmartinez.bsky.social (@yaleschoolofmed.bsky.social) and his work on #InfectiousDisease, #DengueVirus & #COVIDVaccines. Learn more + apply to be a #KSFellow! 🔗 keypoint.keystonesymposia.org/home/septemb... #KeystoneSymposia
keypoint.keystonesymposia.org
September Fellow's Spotlight on Dr. David Martinez
Our September Fellows Spotlight goes to Keystone Symposia Fellow Dr. David Martinez of Yale Medical School who played a critical role in research and development of the COVID-19 vaccines and antibody ...
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Shabaana Khader @khadershabaana.bsky.social · 05/10/2025
Dear #microbiology and #immunology community- I took a break from social media after I deleted my Twitter account, but am back here. Please help me rebuild my community by following me and amplifying this message- I will follow you back. Thank you and I look forward to our many interactions!
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Department of Microbiology, The University of Chicago @uocmicrobiology.bsky.social · 06/10/2025
UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu Apply here apply.interfolio.com/174404
microbiology.uchicago.edu
Department of Microbiology | The University of Chicago
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Nik Joshi @joshilabyale.bsky.social · 02/10/2025
Happy to announce the publication using advanced models to understand how T cells mediate efficient immunoediting in early sarcomas. This was a collaboration between Julie Cheung and Brian Hunt in the lab Thanks to Cancer Cell for publishing our work. www.cell.com/cancer-cell/...
cell.com
Distinct T cell functions enable efficient immunoediting and prevent tumor emergence of developing sarcomas
Cheung et al. describe efficient T cell control of nascent neoantigen+ and nearby neoantigen-negative sarcoma cells, underlying a ∼50% reduction in tumor penetrance. This otherwise imperceptible immun...
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Max Kozlov @maxkozlov.bsky.social · 15/07/2025
NEW: In an unprecedented move, the NIH will soon disinvite dozens of scientists about to take positions on advisory councils that make final decisions on grant funding. NIH staff were told to select others aligned with the Trump administration and told to expect placements by political appointees.
nature.com
Exclusive: NIH to dismiss dozens of grant reviewers to align with Trump priorities
The move would undo years of work, leaving advisory councils understaffed, and without the full expertise needed for reviews.
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Ed Belongia MD @belongia.bsky.social · 20/09/2025
"No vaccine was tested more extensively than the RNA vaccines, and no vaccine was given to more people than the mRNA vaccines, & they were found to be incredibly safe...and effective. They saved 20 million lives, & they stopped a pandemic that was shutting down the world." -Drew Weissman
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Angie Rasmussen @angierasmussen.bsky.social · 04/09/2025
The problem with believing vaccines are dangerous is that by the time you realize you’re wrong, it’s too late and someone you love dies of a preventable disease. Florida is about to find this out the hard way.
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Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · 04/09/2025
RFK Jr. rolled out that old chestnut again about how healthy Americans were in the 60’s, so here’s a fact check. In 1965: -42% of American adults smoked; it’s 11% now. -The infant morality rate was 24.7/1000; it’s 5.6/1000 now. -Overall life expectancy was 70 years; it's about 77 years now.
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Adam Kucharski @adamjkucharski.bsky.social · 02/09/2025
A bizarre dogma has emerged among the anti-mRNA crowd that the only data we have on vaccines is from the original trial papers, rather than the HUGE volume of studies that came out subsequently...
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Carolina Lucas @carolilucas.bsky.social · 26/08/2025
🚨New Paper in Cell 🧵🔎 Happy to share our work led by the @camilahcoelho.bsky.social, on mAbs against mpox. We were very excited (and lucky!) to contribute to this collab. effort. 🦠“Human monoclonal antibodies targeting A35 protect from death caused by mpox”🦠 doi.org/10.1016/j.cell.2025.08.004
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Camila Coelho, PhD MBA @camilahcoelho.bsky.social · 12/08/2025
🚨 New Publication!!! I’m thrilled to share our latest study, “Clonotype-Enriched Somatic Hypermutations Drive Affinity Maturation of a Public Human Antibody Targeting an Occluded Sarbecovirus Epitope”. www.cell.com/cell-reports... [1/4]
cell.com
Clonotype-enriched somatic hypermutations drive affinity maturation of a public human antibody targeting an occluded sarbecovirus epitope
Rao et al. demonstrate that convergent somatic hypermutations in the light chain, enriched within a sarbecovirus-specific public antibody clonotype, drive affinity maturation. This antibody targets a ...
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Greg Folkers @gregfolkers.bsky.social · 15/08/2025
Nature: Cancelling mRNA studies is the highest irresponsibility go.nature.com/3HDx4wD cc Jay Bhattacharya
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David R. Martinez @davidmartinez.bsky.social · 19/08/2025
America Is Abandoning One of the Greatest Medical Breakthroughs www.nytimes.com/2025/08/18/o...
nytimes.com
Opinion | America Is Abandoning One of the Greatest Medical Breakthroughs
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Harmit Singh Malik @harmitmalik.bsky.social · 06/08/2025
To have this paper appear the same day that RFK Jr is canceling all mRNA vaccine funding is further indication that irony is not dead, even though we might all be soon.
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Christina Jewett @by-cjewett.bsky.social · 09/08/2025
A 33-year-old ex-Marine police officer was shot at the CDC by someone who believed he was hurt by the Covid vaccine. The policeman was a father of two with another baby on the way ---> www.nytimes.com/2025/08/09/u...
nytimes.com
Gunman in Deadly C.D.C. Shooting Fixated on Covid Vaccine, Officials Say
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Helen Lazear @lazearlab.bsky.social · 08/08/2025
So proud of Celeste Robles @celeste-robles.bsky.social for being selected as a 2025 Gilliam Fellow! Thrilled to be joining the Gilliam community @hhmi.org www.hhmi.org/programs/gil...
2025 Gilliam Fellows program announcement highlighting graduate student Celeste Robles from UNC Chapel Hill (advisor Helen Lazear)
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David R. Martinez @davidmartinez.bsky.social · 07/08/2025
Beaming with pride that Jordan Polster, a student in my lab at Yale, was selected for the #Gilliam #Fellowship from @hhmi.org I look forward to mentoring Jordan and participating in the various mentorship workshops. Jordan - congrats! And I can’t wait to see your research advance!
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HHMI @hhmi-science.bsky.social · 07/08/2025
Congratulations 2025 Gilliam Fellows and Advisors! 🎉 The Gilliam Fellows Program launches promising PhD students into impactful scientific research careers while fostering inclusive training environments. Through this program, HHMI supports both graduate students and their faculty thesis advisors.
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Ardem Patapoutian @ardemp.bskyverified.social · 31/07/2025
BIG NEWS: “Senate appropriators on Thursday approved an FY26 Labor-HHS bill that included a slight bump in funding for the NIH, with a strong 26–3 bipartisan vote.” Thank you to members of the Senate Appropriations Committee on both sides of the aisle! www.axios.com/pro/health-c...
axios.com
Senate appropriators approve Labor-HHS bill with NIH bump
The vote and lawmaker comments show that most senators aren't going along with the White House's proposed 40% budget cut to NIH.
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Max Kozlov @maxkozlov.bsky.social · 31/07/2025
The NIH budget will INCREASE by $400 million — not slashed by 40%, as Trump proposed — according to a proposal by Senate appropriators, says Sen Murray. "Some have asked if there will even be an NIH by [2029]. The commmittee's resounding message is yes—Congress has your back", she says.
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Jeremy Berg @jeremymberg.bsky.social · 31/07/2025
In preparation of today's mark-up of the NIH appropriations bill in the Senate and other activities, I sent this note to Senator Susan Collins' office. 1/2
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Harmit Singh Malik @harmitmalik.bsky.social · 30/07/2025
Extra kudos and thanks to all the staff at NIH and NSF and other federal funding agencies for working extra hard in very small windows of opportunity to get grants reviewed and funds released before the attention-addled federal policies change again (on an hourly basis).
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The New York Times @nytimes.com · 30/07/2025
Breaking News: Brown University was said to have reached a deal with the Trump administration to restore federal funding. nyti.ms/459nQzY
Brown University's campus. A headline reads: "Brown University Makes A Deal With the White House to Restore Funding." Photo credit: lan MacLellan for The New York Times.
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David R. Martinez @davidmartinez.bsky.social · 23/07/2025
Reviewer #3 feedback.
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Dan of the Year @downwithdan.bsky.social · 19/07/2025
holy shit lmao
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Andy Goodman @agoodmanct.bsky.social · 16/07/2025
New paper! Combining epidemiology and experiments uncovers surprising drug-host-microbiome-pathogen interactions. Congrats @amankumar25.bsky.social, Robyn Tamblyn, and the rest of the team. www.nature.com/articles/s41...
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Ruth Franklin @ruthfranklinlab.bsky.social · 11/07/2025
🎉 Over the moon to share the first paper from my lab!! We discovered an unexpected role for the cytokine OSM in lung epithelial homeostasis and repair. 🧵 1/n www.science.org/doi/10.1126/...
science.org
Macrophage-derived oncostatin M repairs the lung epithelial barrier during inflammatory damage
Tissue repair programs must function alongside antiviral immunity to restore the lung epithelial barrier following infection. We found that macrophage-derived oncostatin M (OSM) counteracted the patho...
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David M Morens @davidmmorens.bsky.social · 03/07/2025
Very depressing to hear that. How can this be happening at NIH? It defies belief.
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David R. Martinez @davidmartinez.bsky.social · 02/07/2025
Lunch outing with the lab to celebrate Jordan’s brilliant qualifying exam (she passed with flying colors)! And, also celebrated a 1%ile score on the lab’s R01 on mucosal vaccines for respiratory viruses. Fingers crossed for the NOA!
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StellaMarie @StellaMarie.bsky.social @stellamarie.bsky.social · 21/06/2025
“The 1793 yellow fever epidemic in Philadelphia was one of the most severe in American history, killing around 5,000 people, or 10% of the city's population. The outbreak began in August near the Delaware waterfront and spread rapidly throughout the summer and fall.” The rich fled to the countryside
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David R. Martinez @davidmartinez.bsky.social · 17/06/2025
🙌🏼 praise be for the judicial branch putting the brakes on the illegal actions of this current administration. Judge Rules N.I.H. Grant Cuts Illegal, Orders Funds Restored www.nytimes.com/live/2025/06...
nytimes.com
Trump Administration Live Updates: Judge Rules N.I.H. Grant Cuts Illegal, Orders Funds Restored
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Ruth Montgomery @rrmsky.bsky.social · 12/06/2025
Real vaccine science, check it out
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David R. Martinez @davidmartinez.bsky.social · 12/06/2025
A paper from our pancoronavirus vaccine P01 grant group is now out in Science Translational Medicine. Here we show that non-stabilized spike delivered as mRNA is sufficient to elicit broadly neutralizing antibodies in monkeys. @alexschaefer.bsky.social www.science.org/doi/10.1126/...
science.org
Nonstabilized SARS-CoV-2 spike mRNA vaccination induces broadly neutralizing antibodies in nonhuman primates
Nonstabilized SARS-CoV-2 spike mRNA vaccination elicited distinct antibodies to either Omicron variants of concern or preemergent sarbecoviruses.
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Dr. Vin Gupta @vinguptamd.bsky.social · 11/06/2025
Kennedy’s ACIP 2.0 is as expected. Headlined by charlatans that have nothing to lose and will rubber stamp ludicrous policies. I strongly urge my fellow healthcare providers to speak up and be unafraid. We must ensure there is accountability through collective action.
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Angie Rasmussen @angierasmussen.bsky.social · 11/06/2025
The process for ACIP membership usually takes years of vetting, particularly for conflicts of interest. Have these people undergone the same level of scrutiny? I'm pretty sure Malone has made money from saying falsely that mRNA vaccines are unsafe.
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Timothy Caulfield @caulfieldtim.bsky.social · 10/06/2025
RFK Jr.’s attack on vaccine experts endangers every American www.statnews.com/2025/06/10/a... via @statnews.com "Kennedy is not fit for the office he holds." "Congress must act. The medical and public health community must speak out. And the public should demand better."
statnews.com
RFK Jr.’s attack on vaccine experts endangers every American
“Our nation’s top health official cannot be trusted to protect America’s children and their families,” writes Richard Besser, pediatrician and president of the Robert Wood Johnson Foundation.
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Prof Gavin Yamey MD MPH @gavinyamey.bsky.social · 10/06/2025
Jay Bhattacharya is decimating health research Here in my state, his cuts are MASSIVE ($566 million in lost funding NC is #2 in terminated grants The impact will be horrific Bhattacharya took $129 million from Duke’s HIV vaccine development efforts; see www.dukechronicle.com/article/2025...
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Matt Wynia @mattwynia.bsky.social · 06/06/2025
~40% cuts to NIH research awards. ~35% cuts to training programs. ~27% cut to internal research. ~30% fewer grants awarded overall. The Common Fund will be cut in half. American science has never faced a threat like this. www.statnews.com/2025/06/06/n... via @statnews.com
statnews.com
NIH details how Trump budget would cut support for grants, training, and research centers
President Trump's 2026 budget proposes cutting NIH grants to universities, academic medical centers, and other institutions by 43%
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Harmit Singh Malik @harmitmalik.bsky.social · 05/06/2025
Remember the day when the cyber truck was unveiled by Elon Musk trying to channel his best Steve Jobs? When he took a hammer to the ‘bulletproof windows’ which were not? Today is better.
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Spencer J Fox @foxandtheflu.bsky.social · 04/06/2025
Losing the US contribution to GAVI is predicted to lead to 1.2 million additional preventable child deaths globally. From our new piece about measles: www.nature.com/articles/s41...
nature.com
Measles is resurging in the Americas and the world is watching - Nature Reviews Microbiology
Measles vaccination rates fell during the COVID-19 pandemic and have yet to recover, fuelling large and disruptive outbreaks globally. Now, a substantial outbreak in the Americas threatens elimination...
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Angie Rasmussen @angierasmussen.bsky.social · 31/05/2025
I grew up in the US in the 1980s, so exceptionalism is a defining trait. My default setting is USA #1. I can’t accept that making America great again means voluntarily stepping off the podium and relinquishing our medals. It’s the least American thing we could ever do.
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Ellen Braaten @ellenbraaten.bsky.social · 29/05/2025
RFK has always a history of making his own reality which requires making stuff up to support his fantasy-reality
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Krutika Kuppalli, MD FIDSA @krutikakuppalli.bsky.social · 29/05/2025
🚨 In a stunningly short-sighted move, HHS just canceled its contract with Moderna to test mRNA vaccines for #H5N1 and other pandemic threats. When the next big outbreak hits, what’s the plan—bleach again? This will come back to bite us. Hard. #BirdFlu #PublicHealth #PandemicPreparedness
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Tim Sheahan @timothysheahan.bsky.social · 28/05/2025
New paper about ACE2 using Merbecovirus. Hot stuff. So hot but you can't Letko. @fviromics.bsky.social and Nick Catanzaro. www.nature.com/articles/s41... #ACE2 #emergingviruses #bats #batman #MERS #HKU5
nature.com
ACE2 from Pipistrellus abramus bats is a receptor for HKU5 coronaviruses - Nature Communications
This work shows that receptor use in merbecovirus is clade-specific by clustering them into clades based on the receptor-binding domain (RBD) of their spike proteins. While MERS-CoV and its close rela...
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David R. Martinez @davidmartinez.bsky.social · 28/05/2025
Definitely fool’s gold. Pun intended.
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Laboratory of Functional Viromics (LETKO) @fviromics.bsky.social · 28/05/2025
Our study screening the majority of all published Merbecovirus RBD’s for cell entry phenotypes is now published in Nature Communications! (1/5) shorturl.at/gYz4E
shorturl.at
ACE2 from Pipistrellus abramus bats is a receptor for HKU5 coronaviruses - Nature Communications
This work shows that receptor use in merbecovirus is clade-specific by clustering them into clades based on the receptor-binding domain (RBD) of their spike proteins. While MERS-CoV and its close rela...
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