Genetic delivery of designed protein nanoparticles displaying the SARS-CoV-2 RBD elicits potent neutralizing antibody and CD8 T cell responses.

We report the first Sin Nombre virus (SNV) genome sequences from the Northwestern United States and the first SNV sequences recovered from voles. Analysis of samples collected from 189 individual rode...

Audio content analysis can be deployed to examine relationships within and between collected works of different music artists, allowing a new approach to comparative analysis of recorded music within ...

Hayashi et al. demonstrate that human touch-induced pleasurable tickling promotes affinity between rats and human hands. This is accompanied by increased OTR expression in the VMHvl, and blocking the ...

Nonstabilized SARS-CoV-2 spike mRNA vaccination elicited distinct antibodies to either Omicron variants of concern or preemergent sarbecoviruses.

This work shows that receptor use in merbecovirus is clade-specific by clustering them into clades based on the receptor-binding domain (RBD) of their spike proteins. While MERS-CoV and its close rela...

Researchers identified an unusual genetic mutation in orange domestic cats that has not been found in any other animal, according to a new study.

Vaccines against emerging SARS-CoV-2 variants and sarbecoviruses with pandemic potential must elicit a robust humoral immune response in a population imprinted with the SARS-CoV-2 spike (S) protein. H...

The whole-genome sequences of herding dogs reveal how selection has sculpted the unique behavioral traits.

Here, Bignardi et al. report on a study of over 9,000 Swedish twins that indicates the ability to enjoy music is influenced by multiple partly distinct genetic factors.

Emerging coronaviruses like SARS-CoV, SARS-CoV-2, and MERS-CoV cause a range of disease outcomes in humans from an asymptomatic, moderate, and severe respiratory disease that can progress to death but...

The west Africa Ebola disease epidemic (2014–16) marked a historic change of course for patient care during emerging infectious disease outbreaks. The epidemic response was a failure in many ways—a slow, cumbersome, and disjointed effort by a global architecture that was not fit for purpose for a rapidly spreading outbreak. In the most affected countries, health-care workers and other responders felt helpless—dealing with an overwhelming number of patients but with few, if any, tools at their disposal to provide high-quality care.

Animal models will inform our understanding of Long Covid and will aid in identifying therapeutic targets.

Martinez et al. demonstrate proof of concept that a single ferritin nanoparticle vaccine displaying the receptor-binding domains of MERS-related and SARS-related zoonotic, epidemic, and pandemic coro...