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Ruth Montgomery

@rrmsky.bsky.social
1.1K followers 251 following 41 posts

Immunologist at Yale School of Medicine Associate Dean for Scientific Affairs @YaleMed Innate immunity ❤️

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Ruth Montgomery @rrmsky.bsky.social · 10/09/2026
Congratulations to our wonderful colleague Dr. Erica Herzog @yalemed.bsky.social, we look forward to continuing to work with you and all of yoru section!
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Ruth Montgomery @rrmsky.bsky.social · 31/08/2026
Amazing new dimensions of multiplex tissue analysis--congratulations Lingyan Shi and my Yale colleagues! @rongfan8.bsky.social @yalemed.bsky.social
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HHMI @hhmi-science.bsky.social · 23/08/2026
2 genetically identical mice. Same infection, same bacterial load, but only 1 lives. Why? #HHMIInvestigator Janelle Ayres spent decades finding out, & her answer — survival can come through cooperating w/pathogens, not just killing them — could reshape how we treat infectious disease: bit.ly/4qsuWJW
Janelle Ayres in her lab.
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Ruth Montgomery @rrmsky.bsky.social · 18/08/2026
The most pressing questions in immunology — why do people respond differently to infection, vaccination or therapy? Why do some develop chronic inflammatory disease while others remain resilient? See high-dimensional public data resources. @hipcproject.bsky.social @yalemed.bsky.social rdcu.be/fAwms
nature.com
From data to discovery: a unified framework for human immunology
Nature Immunology - High-throughput, high-dimensional profiling technologies have transformed the ability to generate and test hypotheses of human immunology. Investment in infrastructure has...
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Ruth Montgomery @rrmsky.bsky.social · 14/08/2026
Hi @msmacrophage.bsky.social wishing you a great march and great discoveries to all
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Admirable Women @admirablewomen.bsky.social · 26/07/2026
Chemist & X-ray crystallographer Rosalind Franklin's meticulous research was instrumental in uncovering DNA's molecular structure. Most famous for her role in the DNA double helix discovery, her work also revolutionized our understanding of viruses & coal. She was born #OTD in 1920. #WomenInSTEM 🧵
A classic, black-and-white studio portrait of a young Dr. Rosalind Franklin (1920–1958), the pioneering British chemist and X-ray crystallographer whose data was foundational to uncovering the double-helix structure of DNA. Captured from the chest up, Franklin sits in a three-quarter pose, her body angled slightly toward the left while her gaze directly meets the viewer. She possesses a calm, intelligent, and subtly enigmatic expression, with her dark hair neatly parted on the side and styled back away from her face. She wears a dark, long-sleeved button-down blouse with structured shoulders, a sharp collar, and fabric buttons down the front placket. The background is a soft, minimalist studio gradient of neutral grays that creates a gentle vignette effect, casting a soft light on the right side of her face. The composition is clean, formal, and balanced, evoking a mood of quiet determination, dignity, and brilliant intellectual poise characteristic of the early 20th-century scientific vanguard.
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Ruth Montgomery @rrmsky.bsky.social · 03/06/2026
Another red alert for American science | Science www.science.org/doi/10.1126/...
science.org
Another red alert for American science
Although research has bipartisan support in the US Congress, and trust in science is above 75% across the country, the Trump administration seems as determined as ever to mortally wound the nation’s s...
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Ruth Montgomery @rrmsky.bsky.social · 09/05/2026
m.yale.edu/dh3y
m.yale.edu
Yale Physician-Scientists Pioneer Fetal Gene Therapy for Cystic Fibrosis
David Stitelman, MD, has received funding from the Cystic Fibrosis Research Institute to advance his collaborative research on a novel fetal therapy approach
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Yale University @yale.edu · 08/05/2026
Can eating less help us age better? Research has long shown that cutting calories can improve lifespan in some species, but it’s not always practical or healthy for people. Now, a study from immunobiologist Vishwa Deep Dixit is exploring how we might get those same benefits without the risks.
bit.ly
Cutting Calories to Slow Aging--Without Compromising Health
Scientists found a potential target for achieving the healthy longevity that can come with calorie restriction, without the negative effects it can have on the
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Amy C Fan (she/her) @amycfanphd.bsky.social · 29/04/2026
Excited to announce our new study (w/ @maxkrummel.bsky.social) published today @nature.com: Macrophages “hold our living identities” by taking tiny bites from living cells and presenting this information to CD8 T cells. www.nature.com/articles/s41... #immunology #cellbiology @immunox.bsky.social
nature.com
Submicrometre sampling of living cells by macrophages - Nature
Macrophages can sample antigens from living cells through a trogocytosis-like mechanism that routes ingested material away from degradation, a finding that delineates a previously unknown pathway...
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precvaccines.bsky.social @precvaccines.bsky.social · 29/04/2026
Thank you to the incredible panel of researchers who presented at the Immune Development in Early Life Hot Topic Symposium at @pasmeeting.bsky.social #PAS2026 L to R: Dr. Xiaobin Wang, Dr. Ofer Levy, Dr. Oluwabunmi Olaloye, Dr. Octavio Ramilo, Dr. Paolo Palma. #vaccines #IDEAL #EarlyLifeImmunity
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Ruth Montgomery @rrmsky.bsky.social · 22/04/2026
We focus on human immunology to understand the effects of #aging. Great science being shared at @hipcproject.bsky.social annual meeting by @adamtanguay.bsky.social from @yalemed.bsky.social
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HIPC @hipcproject.bsky.social · 18/04/2026
After the HIPC Symposium, meet some of our researchers and speakers at our Immunology Superbooth in the exhibition center! At booths #736 #738 @aai.org
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HIPC @hipcproject.bsky.social · 18/04/2026
@skleinstein.bsky.social presenting on @immportdb.bsky.social and @hipcproject.bsky.social work at #AAI2026 💡
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Ruth Montgomery @rrmsky.bsky.social · 14/04/2026
We have age-associated macrophages in visceral fat making C3a and increasing inflammation. C'mon macrophages, we need your help here. Wonderful new paper from Dixit lab @yalemed.bsky.social #SenNet www.nature.com/articles/s43...
nature.com
Exoproteome of calorie-restricted humans identifies complement deactivation as an immunometabolic checkpoint reducing inflammaging - Nature Aging
Applying proteomics to longitudinal plasma samples from calorically restricted participants of the CALERIE trial, Mishra, Kim and colleagues link complement protein C3a to inflammaging. In aged mice, ...
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HIPC @hipcproject.bsky.social · 07/04/2026
#AAI2026: Besides our #HIPC Guest Symposium, we will have two presentations from members of our #ImmuneSpace team ( @skleinstein.bsky.social & Jian Xing) on Saturday, April 18th! Hope to see you there at @aai.org 💬💡🙂
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precvaccines.bsky.social @precvaccines.bsky.social · 02/04/2026
Members of our Data Management and Analysis team had a great time at NextGenOmics, Spatial & Data US! Joann Diray Arce, PhD gave a talk on ImmuneVISTA and MultiOMICs in #vaccine research #NGOUS2026 #OGPREMED #vaccines
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Ruth Montgomery @rrmsky.bsky.social · 02/04/2026
Congratulations to my wonderful Yale colleagues!
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Ruth Montgomery @rrmsky.bsky.social · 30/03/2026
Working together to advance understanding of human immunology. Well said Holden! @hipcproject.bsky.social
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Prof Frank McDonough @fxmc1957.bsky.social · 26/03/2026
FACT OF THE DAY. 26 March 1953. In a huge medical breakthrough, US medical researcher Dr Jonas Salk announced that he had created the first polio vaccine. Polio cases fell from 58,000 per year in 1952 to 6,000 by 1958. Salk’s vaccine was replaced by a new one developed by Albert Sabin in 1962.
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American Aging Association @americanaging.bsky.social · 25/03/2026
🎉 Congrats to #AGE2026 Early Career Scholar Awardee Piper Wilburn- #IndianaUniversitySchoolOfMedicine. Recognized by the #AmericanAgingAssociation, her research studies how the bone marrow niche shapes stem cell function and transplant outcomes in aging. #Geroscience #AgingResearch
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Jeremy Berg @jeremymberg.bsky.social · 25/03/2026
Good discussion of the disappearing NIH Notices of Funding Opportunity (NOFOs). elizabethginexi.substack.com/p/the-nofo-g...
elizabethginexi.substack.com
The NOFO Graveyard
A Response to NIH's Defense of Its Vanishing Funding Opportunities
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Dick Zoutman @dickzoutman.bsky.social · 25/03/2026
www.tandfonline.com/doi/full/10....
tandfonline.com
Detection of SARS-CoV-2 RNA on air purifier filters in university spaces without symptomatic or confirmed cases
Understanding the seasonality and prevalence of respiratory viruses in indoor environments is essential for protecting public health in the post-pandemic era. This study investigated the presence o...
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Dr. Dawn Bowdish @msmacrophage.bsky.social · 23/03/2026
I love phagocytosis- the most ancient form of immunity (estimated at 1 billion yrs old!). Lucky to geek out with all the other macrophage and neutrophil geeks at beautiful Keble college, Oxford.
Sign of the European Phagocyte WorkshopMe surrounded by the ridiculous beauty that is every Oxford college.
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Ruth Montgomery @rrmsky.bsky.social · 26/02/2026
New clues to understand #HealthyAging from @yalemed.bsky.social studying longevity in nature. #SenNet www.science.org/doi/epdf/10....
science.org
Immunometabolic resistors of aging in long-lived golden spiny mice
You have to enable JavaScript in your browser's settings in order to use the eReader.
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Simon Lab @vivianasimonlab.bsky.social · 04/02/2026
Sharing on behalf of Dr. Florian Krammer for those interested - his podcast is great! Episode 0 of my new podcast viroLOGICAL is online. This first episode is a little longer and gives a general overview of viruses and viral diseases. Find it on Apple, Spotify, and Podigee: virological.podigee.io
virological.podigee.io
viroLOGICAL
Florian Krammer is a virologist and vaccine developer. In his podcast viroLOGICAL he will talk about viruses on a weekly basis – from historical pandemics to current developments. A Podcastwerkstatt O...
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Dr. Dawn Bowdish @msmacrophage.bsky.social · 04/02/2026
Learning lots about #lung autoimmunity as a contributor to severe #asthma from Dr Manali Mukherjee from #TheFirestone. Great reminder that blood is not always the right place to sample for autoimmunity -sputum can be a much more informative marker.
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Denis Wirtz @deniswirtz.bsky.social · 03/02/2026
Both chambers of Congress have now passed the FY26 minibus with NIH provisions. The President will sign. (1) $48.7 billion for NIH (2) Full IDC recovery (3) No more multi-year funding (4) No NIH reorganization, maintaining the current IC structure.
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Ruth Montgomery @rrmsky.bsky.social · 03/02/2026
m.yale.edu/dfrz
m.yale.edu
Berna Sozen Wins Vilcek Prize for Creative Promise in Biomedical Science
Berna Sozen, PhD, was awarded the prize in recognition of her research, which has enhanced understanding of embryonic development.
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Ellen Foxman @ellenfoxman.bsky.social · 02/02/2026
Thank you to Bob McDonald for hosting me on @CBCRadioCanada to discuss our work @yaleschoolofmed.bsky.social on what leads to variation in common cold virus infections and how we tackled this using nasal organoids. Listen here: www.cbc.ca/listen/live-...
cbc.ca
© CBC/Radio-Canada 2026. All rights reserved.
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Ruth Montgomery @rrmsky.bsky.social · 30/01/2026
Glad to join today in teaching #CyTOF for Yale's Computational Proteomics course directed by Dr. Maria Rodriguez Martinez. Multidimensional single cell immune profiling for #HIPC takes a team including Dr. Adam Tanguay and Dr. Ashish Shelar.
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Edward Doherty PhD. @drtcell.bsky.social · 08/01/2026
My most recent manuscript is available from @pnas.org . We describe a population of inflammatory cytokine MIF responsive T cells and their importance in Rheumatoid Arthritis pathogenesis.
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Ruth Montgomery @rrmsky.bsky.social · 18/12/2025
Solo markers were interesting but combining gene SNPs and plasma metabolite data showed predictions for severe #COVID. That's why we study the whole #SystemsImmunology #BigScience #Teamwork
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Admirable Women @admirablewomen.bsky.social · 15/12/2025
Dr. Leila Denmark co-developed the pertussis (whooping cough) vaccine. World's oldest practicing pediatrician until she retired at age 103 (after 73 yrs). At the time of her death at age 114 & 60 days, she was the 5th-oldest validated living person in the world & 3rd-oldest in the US. #WomenInSTEM
A black-and-white photo shows Dr. Leila Denmark (center), an elderly woman with glasses, seated and smiling while looking at a baby who is laughing and facing her. Another younger woman is also seated to the right, laughing and placing her hand near the baby's midsection. The scene suggests a warm, inter-generational interaction, possibly in a clinical or home setting. Dr. Denmark was a pioneering pediatrician, known as the world's oldest practicing pediatrician upon her retirement at age 103.
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Andres Hidalgo @drusqui.bsky.social · 12/12/2025
I am excited to share our new paper @JExpMed led by our one and only #Alejandra_Aroca
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The American Association of Immunologists @aai.org · 10/12/2025
Representative Betty McCollum (D-MN, 4th) met with AAI Councilors Gwendalyn Randolph, Steve Jameson, and CPA Chair Lauren Ehrlich! They had a great conversation about how crucial robust funding is for NIH. Thank you for the support! #AAIadvocacy
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The American Association of Immunologists @aai.org · 10/12/2025
AAI Councilors Donna Farber, Avery August, and Laurie Harrington had a wonderful meeting with staff from Rep. Josh Riley’s (D-NY, 19th) office, discussing the importance of NIH funding and science-based policy. #AAIadvocacy
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Eric Topol @erictopol.bsky.social · 02/12/2025
The NIH grant cuts in 2025 www.nytimes.com/interactive/...
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Mary Munson @marymunson4.bsky.social · 02/12/2025
Super excited for the upcoming #cellbio2025 @ascbiology.bsky.social @embo.org meeting in Philadelphia! Check out the Special President's session on "The Rising Tide of Science Denial" on Saturday at 1pm!
Image of the four speakers for the "Rising Tide of Science Denial", special President's session on Saturday Dec 6 at 1pm:  Kenneth R. Miller, Michael Mann, Paul Offit, and Gale M. Sinatra
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Research Centers Collaborative Network (RCCN) @rccn-aging.org · 01/12/2025
We are proud to feature 2025 RCCN Pilot Awardees Lauren Ferrante and Kathryn Callahan in this Pilot Awardee Spotlight! Learn more about their Inter-NIA Center pilot project here: bit.ly/4izqwNF #Frailty #AgingResearch
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Prof Peter Hotez MD PhD DSc(hon) @peterhotezmdphd.bsky.social · 17/11/2025
Honored to be recognized as one of 25 Best Leaders by @usnews.com including 5 in the Health category. I look forward to meeting some extraordinary colleagues at an upcoming event in Wash DC www.usnews.com/news/leaders...
Health Category
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Stand Up for Science! @standupforscience.net · 03/10/2025
The Trump admin has been targeting whistleblowers, from the #FEMA36 to the countless other patriotic public servants and scientists across NIH, CDC, NASA, and more who spoke out about the danger posed by the chaos in our federal agencies. This is an concerted, autocratic effort to silence dissent.
theguardian.com
RFK Jr fires top NIH scientist weeks after she files whistleblower complaint
Jeanne Marrazzo’s complaint reportedly involved the Trump administration’s hostility toward vaccines
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Ruth Montgomery @rrmsky.bsky.social · 03/10/2025
New research from Dixit lab @yalemed.bsky.social showing nerve-associated macrophages (NAMs) decline in aging which impairs the breakdown of fat and increases inflammaging. Dixit addresses the biology of aging and intercommunication between nerves and macrophages. www.nature.com/articles/s43...
nature.com
Nerve-associated macrophages control adipose homeostasis across lifespan and restrain age-related inflammation - Nature Aging
Gonzalez-Hurtado, Leveau and colleagues characterize adipose resident tissue macrophages across lifespan in mice, finding that nerve-associated macrophages, which mitigate inflammation and control lipolysis and catecholamine resistance, are lost during aging.
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Larry Ferlazzo @larryferlazzo.bsky.social · 19/09/2025
Taliban Bans Books by Women in Afghanistan’s Universities www.nytimes.com/2025/09/19/w...
nytimes.com
Taliban Bans Books by Women in Afghanistan’s Universities
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Ruth Montgomery @rrmsky.bsky.social · 20/09/2025
Congratulations to our outstanding @yalemed.bsky.social colleague @virusesimmunity.bsky.social
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Ruth Montgomery @rrmsky.bsky.social · 04/09/2025
Count on #macrophages to promote health! Congratulations to my @yalemed.bsky.social colleagues for this very novel paper.
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Jonathan Kagan @jkagan1.bsky.social · 23/08/2025
mRNA technologies: Unlimited potential to improve human health. I spoke with the fantastic Erin Shumaker at POLITICO to discuss this topic and its applications to cancer, autoimmunity and beyond. @erinlschumaker.bsky.social @politico.com @cornertx #mRNA #Cancer politi.co/3VjfRvu
politi.co
Losing the mRNA arms race
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Nature Microbiology @natmicrobiol.nature.com · 01/08/2025
#Resource Proteomic characterization of varicella-zoster virus–host protein interactions and infection-induced changes in a neuronal cell line identifies potential targets for drug discovery and molecular insights into severe disease. #MicroSky www.nature.com/articles/s41...
nature.com
Multi-proteomic profiling of the varicella-zoster virus–host interface reveals host susceptibilities to severe infection - Nature Microbiology
Proteomic characterization of varicella-zoster virus–host protein interactions and infection-induced changes in a neuronal cell line identifies potential targets for drug discovery and molecular insig...
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HIPC @hipcproject.bsky.social · 06/08/2025
Come get your curated #immune #assays from 1,000s of human subjects at our website immunespace.org 🧪 #immunology #IDSky #ImmuneSky immunespace.org/query/filters giphy.com/gifs/Giflyti...
giphy.com
Analyze Lucky Charms GIF by Giflytics - Find & Share on GIPHY
Discover & share this Analyze Lucky Charms GIF by Giflytics with everyone you know. GIPHY is how you search, share, discover, and create GIFs.
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ASM @asm.org · 04/08/2025
On Aug. 1, ASM & partner societies filed an expanded amicus brief with SCOTUS to defend scientific integrity & protect early-career researchers. The brief highlights the harm caused by NIH grant terminations, including canceling the MOSAIC program. asm.org/press-releas...
asm.org
Scientific Societies File Supreme Court Amicus Brief in Support of NIH Grantees
ASM and fellow societies filed an amicus brief with the Supreme Court, calling for the swift restoration of NIH grant funding supporting early-career scientists, such as the MOSAIC program.
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