Reposted by Constantin Ahlmann-Eltze
Our work on systematic perturb-seq of primary human T cells is now out in Cell 🎉
www.cell.com/cell/fulltex...
It's been a privilege to work with @ronghuizhu.bsky.social between @jkpritch.bsky.social @marsonlab.bsky.social labs, with a dream-team of co-authors ❤️
Highlights in preprint thread👇
cell.com
Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits
A dynamic atlas of gene regulation was generated by perturbing every expressed gene
across 22 million primary human CD4+ T cells under resting conditions and following
re-stimulation. The resulting ma...
![wrap_in_df <- function(...){
dots <- rlang::enquos(...)
eval_in_mtcars(data.frame(!!! dots))
}
wrap_in_tibble <- function(...){
dots <- rlang::enquos(...)
eval_in_mtcars(tibble::tibble(!!! dots))
}
eval_in_mtcars <- function(expr){
quo <- rlang::enquo(expr)
rlang::eval_tidy(quo, data = mtcars[1:3,])
}
wrap_in_df(mpg * 2, cyl + 3)
#> X.mpg...2 X.cyl...3
#> 1 42.0 9
#> 2 42.0 9
#> 3 45.6 7
wrap_in_tibble(mpg * 2, cyl + 3)
#> Error: object 'mpg' not found](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:pa4xdweapw6gnh42xqptt6vb/bafkreihxqsxhceomx7l4lv6g5zk5ocw4vy7mlpyxf7fg5qssa5gnvjbe4q)
