iiinova — where your digital self keeps evolving

Reposted by Noelia Ferruz

christofseiler.bsky.social @christofseiler.bsky.social · 14/01/2026

Save the date: April 9 from 4pm to 6pm CET. Our department is hosting an online seminar with @noeliaferruz.bsky.social @sdomcke.bsky.social @const-ae.bsky.social who will talk about models for protein design, large-scale perturbation screens, and benchmarking of perturbation prediction models.

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Arnau Sebé-Pedrós @arnausebe.bsky.social · 23/10/2025

The CRG PhD call is now open. Exciting opportunities across diverse topics and within a world-class scientific environment. Our group is offering one PhD position to study chromatin evolution. Consider applying or share with anyone who might be interested! www.crg.eu/en/content/t...

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Protein Structure Evolution (ProSE) Seminar @proteinstructure.bsky.social · 25/10/2025

Protein Structure Evolution (ProSe) Seminar is now on BlueSky! Every 2nd Tuesday, 4PM GMT. Sign-Up: tinyurl.com/prose-seminar2 Organized by Claudia Alvarez Carreño, Zachary Ardern, Lars Eicholt, Carolina Sanchez-Rocha, Sergio Romero Romero and Md. Hassan Uz-Zaman.

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Centre de Regulació Genòmica (CRG) @crg.eu · 23/10/2025

Are you looking for a PhD? Join us in Barcelona! You'll dive into a community of >100 PhD students from 30 countries exploring the frontiers of biology. You can also join an online workshop on 6 November (15:00 CET) to learn how to find the right lab for you. More info: www.crg.eu/en/content/t...

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UPF Medicine and Life Sciences @melisupf.bsky.social · 20/10/2025

#Research #Biomedicine Generative AI is more efficient than nature at designing proteins to edit the genome 🧬💻✂️ This is the conclusion of research published at @natbiotech.nature.com by @marcguellc.bsky.social Integra Therapeutics & @noeliaferruz.bsky.social - @crg.eu 📰 tuit.cat/n7ap6

Dimitrije Ivančić (co-first author of the paper), Marc Güell (ICREA researcher and CSO of Integra Therapeutics), Avencia Sanchez-Mejías (CEO of Integra Therapeutics) and Alejandro Agudelo (co-first author of the paper)

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Dimitrije @biodimi.bsky.social · 02/10/2025

This work has been possible thanks to an incredible team effort w/ Alejandro, @marcguellc.bsky.social @noeliaferruz.bsky.social and the integra therapeutics team!

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ceej @ceej.online · 30/08/2025

my father-in-law is a “I know a guy” Guy. sadly all the old Guys are aging out of the Guy Economy. Guys are fundamentally incompatible with Hustle Culture because it’s not about “winning” a deal, it’s about collecting favors and goodwill in a mutually-beneficial cycle. protect your local Guy Economy

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CATH-Gene3D @cathgene3d.bsky.social · 22/08/2025

CATH turns 30 years old this year! We are organising a 1-day symposium on September 16th at UCL, highlighting recent AI-based developments to enhance protein family classifications, annotations and analyses. www.eventbrite.co.uk/e/protein-an...

eventbrite.co.uk

Protein Annotations in the age of AI

A not-for-profit symposium hosted at UCL - more details about speakers and venue below.

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Loretta Robinson @lorettarobinson.bsky.social · 21/08/2025

Woke up this morning in Greenland. It is game time for my cameras. National Geographic Endurance safely crossed the Denmark Straight and into this fjord! #EastCoastKin #photography #Greenland

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Liana Lareau @lianafaye.bsky.social · 07/08/2025

This preprint from Helen Sakharova is one of the coolest things to come out of my lab: “Protein language models reveal evolutionary constraints on synonymous codon choice.” Codon choice is a big puzzle in how information is encoded in genomes, and we have a new angle. www.biorxiv.org/content/10.1...

biorxiv.org

Protein language models reveal evolutionary constraints on synonymous codon choice

Evolution has shaped the genetic code, with subtle pressures leading to preferences for some synonymous codons over others. Codons are translated at different speeds by the ribosome, imposing constrai...

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AI x Bio Discovery @aixbiobot.bsky.social · 01/08/2025

Evaluating zero-shot prediction of protein design success by AlphaFold, ESMFold, and ProteinMPNN [new] Zero-shot protein design assessment filters, but accuracy predicting success is limited.

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Reposted by Noelia Ferruz

Martin Pacesa @martinpacesa.bsky.social · 29/07/2025

Thank you everyone for the congratulations and the large number of applications! I want to specifically encourage applications for these positions: * Postdoc in structural biology (cryoEM, ideally with X-ray too) * Full time lab manager/technician with wetlab experience

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Gina El Nesr @ginaelnesr.bsky.social · 28/07/2025

Uncancelled! 🥳

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Manuel Irimia @mirimiam.bsky.social · 23/07/2025

🚨🚨🚨 Please RT! We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets. Deadline: 30/09/25👇

upf.edu

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Noelia Ferruz @noeliaferruz.bsky.social · 25/07/2025

Join Martin’s new lab, great location, super cool project, and the best advisor! What’s not to like?

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Michael Hothorn @structplantbio.bsky.social · 20/07/2025

Struct bio ms titles over the years 1965 - A three-dimensional model of X 1985 - The structure of X 1995 - The structure of X reveals Y 2005 - Structural basis of 2015 - The molecular mechanism of 2025 - Harnessing AlphaFold

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BK. Titanji @boghuma.bsky.social · 19/07/2025

The internet remains undefeated 😂😅

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Phil Holliger @philholliger.bsky.social · 14/07/2025

We are looking to recruit a tenure track group leader in the field of Chemical/Synthetic Biology (in the broadest sense) to lead a research program within the Division of Protein & Nucleic Acid Chemistry ( www.jobs.ac.uk/job/DNW809/r... ) at the MRC Laboratory of Molecular Biology (LMB).

jobs.ac.uk

Research Group Leader in Chemical/Synthetic Biology at MRC Laboratory of Molecular Biology

Start your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top...

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Noelia Ferruz @noeliaferruz.bsky.social · 09/07/2025

An insightful thread by Miguel as usual! - worth reading

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Andrea Hunklinger @ahunklinger.bsky.social · 25/06/2025

In our newest preprint, we discuss current explainable AI (XAI) methods. We divided the workflow of a generative decoder-only model into four information contexts for XAI: training dataset, input query, model components, and output sequence. See here: arxiv.org/abs/2506.19532 @aichemist.bsky.social

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Andrea Hunklinger @ahunklinger.bsky.social · 25/06/2025

Are you curious about what protein language models learn? Check out our newest preprint! 🚀https://arxiv.org/abs/2506.19532 We reviewed explainable AI (XAI) techniques across all parts of the generative protein design workflow and discussed their applications, limitations, and untapped potential!

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Noelia Ferruz @noeliaferruz.bsky.social · 07/07/2025

Noooo😭 This was the BEST workshop at NeurIPS!!

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Noelia Ferruz @noeliaferruz.bsky.social · 05/07/2025

This is absolutely nuts and I wonder how the future of peer review is gonna look like

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Noelia Ferruz @noeliaferruz.bsky.social · 30/06/2025

An excellent assay on the fall of critical thinking

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Pascal Notin @pascalnotin.bsky.social · 18/06/2025

🚨 New paper 🚨 RNA modeling just got its own Gym! 🏋️ Introducing RNAGym, large-scale benchmarks for RNA fitness and structure prediction. 🧵 1/9

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Elena Shekhova @lumipie.com · 16/06/2025

Then, according to this doctor's logic, why do whales have menopause? 🧪

A figure from PMID: 36588114 with the following description: Post-reproductive lifespan across species. The human female is one of a few selected species of mammals with a significant post-reproductive lifespan. The significance of menopause is extensively being debated on whether it is a vestigial evolutionary inheritance or has crucial implication in conferring evolutionary survival of the fittest to our early days’ ancestors as been reproduced from Ellis et al.

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Reposted by Noelia Ferruz

Kevin K. Yang 楊凱筌 @kevinkaichuang.bsky.social · 11/06/2025

End-to-end differentiable homology search for protein fitness prediction. @yaringal.bsky.social @deboramarks.bsky.social @pascalnotin.bsky.social arxiv.org/abs/2506.089...

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Reposted by Noelia Ferruz

Cristina Viéitez @crisvieitez.bsky.social · 11/06/2025

Congratulations to all the 2025 Awardees of L’ Oréal- UNESCO For Women in Science & Thanks L’ Oréal Spain for the fantastic networking event!! 💜 #WomenInScience #newPI

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Noelia Ferruz @noeliaferruz.bsky.social · 10/06/2025

People always come up with the best of names?!

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Reposted by Noelia Ferruz

Centre de Regulació Genòmica (CRG) @crg.eu · 30/05/2025

Endinsa’t en una vivència sensorial única que connecta ciència i art immersiu. “SEEING: Un ull i una caixa” arriba del 5 al 14 de juny al Centre Cívic Convent de Sant Agustí (Carrer del Comerç 36, Barcelona). www.crg.eu/en/event/see...

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Kevin K. Yang 楊凱筌 @kevinkaichuang.bsky.social · 02/06/2025

Do protein language models store different structural elements in factorizable subnetworks? To find out, we masked out PLM weights to suppress performance on CATH subcategories or secondary structure elements while maintaining performance on other sequences or residues.

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Noelia Ferruz @noeliaferruz.bsky.social · 23/05/2025

@isabellease.bsky.social is drawing amazing artwork for each speaker at #VariantEffect25 - crazy beautiful and super good summaries in all cases, have a look🤯

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Jonathan Frazer @jonnyfrazer.bsky.social · 23/05/2025

Day 3 of #VariantEffect25 and what a beautiful morning! 🌞🌊🧬 First up: Tim Whitehead presents An experimental platform for learning antibody molecular recognition

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Jonathan Frazer @jonnyfrazer.bsky.social · 21/05/2025

Back from the #VariantEffect25 coffee break and on to @nickywhiffin.bsky.social who is Interpreting variation in small nuclear RNAs in neurodevelopmental disorders. (Absolutely stoked to be seeing her present live. I’ve been looking forward to this for years!)

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Jonathan Frazer @jonnyfrazer.bsky.social · 21/05/2025

Next at #VariantEffect25 we have @pascalnotin.bsky.social who is Advancing Protein Fitness Prediction via Differentiable Retrieval and Cross-Landscape Transfer Learning #AI #ProteinML

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Jonathan Frazer @jonnyfrazer.bsky.social · 21/05/2025

A one-slide intro to retrieval!

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Jonathan Frazer @jonnyfrazer.bsky.social · 21/05/2025

Good morning #VariantEffect25! Kicking things off we have Mafalda Dias, @bennibolo.bsky.social @muffley.bsky.social welcoming us to this 8th annual symposium. We have 250 in-person participants, 60 people online, from 20 countries!

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Jonathan Frazer @jonnyfrazer.bsky.social · 19/05/2025

Welcome to everyone arriving in Barcelona and the @crg.eu today ahead of #VariantEffect25! 🌞🌊🧬 Can’t wait to catch up at the workshop tomorrow!

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Al Jord Lab @aljordlab.bsky.social · 08/05/2025

We have two open Master’s internship projects for the 2025/2026 academic year in our lab! 🔬🧬 You can apply directly through the BIST website: mmres.bist.eu/research-pro... We’re looking forward to hearing from you! 👋 @crg.eu @prbb.org @upf.edu

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Tomas Marques Bonet @tmarquesbonet.bsky.social · 19/05/2025

Postdoc opportunity! The Comparative Genomics lab (@IBE_Barcelona, @UPFBarcelona) is seeking a postdoc with experience to work on environmental DNA and mammalian monitoring together with @estherlizano ! CVs -> cvtmblab@gmail.com #postdoc #genomics #eDNA #conservation #Barcelona

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Rua M. Williams @fractalecho.bsky.social · 03/05/2025

If you're a grad student or an undergrad interested in research I need to you listen to me very carefully. You cannot learn to write good research papers if you do not read good research papers. Stop asking LLMs to summarize papers for you.

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