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Will Townes

@willtownes.bsky.social
123 followers 282 following 14 posts

Asst Prof at Carnegie Mellon Stats Dept interested in infectious disease, genomics, time series, and discrete stable distributions.

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Reposted by Will Townes
Gennady Gorin @goringennady.bsky.social · 09/03/2026
The empty drops you threw out in your single-cell RNA sequencing analysis might be hiding mysterious things 👀 check out our bioRxiv preprint! The empty drops do not contain cells. Yet we can still use them to learn interesting things about biology and technology. 1/
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Will Townes @willtownes.bsky.social · 11/10/2025
Tenure track job opportunity in our department! www.cmu.edu/dietrich/sta... #statistics
cmu.edu
Open Position: Assistant Professor of Statistics & Data Science - Statistics & Data Science - Dietrich College of Humanities and Social Sciences - Carnegie Mellon University
The Department of Statistics & Data Science invites applications for a tenure track position at the rank of Assistant Professor starting in Fall 2026.
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Will Townes @willtownes.bsky.social · 29/09/2025
Are you interested in concentration inequalities? Curious about whether there is a middle ground between subexponential and subgaussian bounds? Want to know how this all interacts with exponential tilting? Then check out my new paper recently published in TMLR: openreview.net/forum?id=BQB...
openreview.net
Exponential tilting of subweibull distributions
The class of subweibull distributions has recently been shown to generalize the important properties of subexponential and subgaussian random variables. We describe alternative characterizations of...
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Will Townes @willtownes.bsky.social · 26/08/2025
Thoughts on peer review: willtownes.github.io/blog/2025/08...
willtownes.github.io
research profile and technical blog
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Reposted by Will Townes
James Munday @jdmunday.bsky.social · 09/06/2025
We have a new preprint 📝 *Post-sampling degradation of viral RNA in wastewater impacts the quality of PCR-based concentration estimates* Now on bioRxiv doi.org/10.1101/2025... with @tanjastadler.bsky.social, trj2.bsky.social, Christoph Ort and others
doi.org
Post-sampling degradation of viral RNA in wastewater impacts the quality of PCR-based concentration estimates
Successful wastewater-based infectious disease surveillance programs depend on regular, reliable molecular detection of nucleic acids in municipal wastewater systems. This process is challenged by the...
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Will Townes @willtownes.bsky.social · 21/07/2025
Anyone else having trouble connecting to github due to a "potential security issue"?
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Will Townes @willtownes.bsky.social · 01/07/2025
Benchmarking study of single-cell feature selection finds deviance to be an effective criterion: doi.org/10.1093/bib/... . Try it yourself with our ( @kstreet.bsky.social @stephaniehicks.bsky.social @davi1893.bsky.social ) scry package @bioconductor.bsky.social : doi.org/doi:10.18129... #genomics
doi.org
Characterizing efficient feature selection for single-cell expression analysis
Abstract. Unsupervised feature selection is a critical step for efficient and accurate analysis of single-cell RNA-seq data. Previous benchmarks used two d
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Will Townes @willtownes.bsky.social · 03/06/2025
Currently teaching data science to CMU students in beautiful Monteverde, Costa Rica! Students are working with real data from community partners: eg, permitting for new construction, flow rates from springs that supply drinking water, bell bird calls, and macroinvertebrate water quality indicators
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Will Townes @willtownes.bsky.social · 14/03/2025
Overview of infectious disease forecasting and our Delphi research group @cmu.edu by Roni Rosenfeld: boxcast.tv/view/opening... (start at 20 min mark) delphi.cmu.edu
boxcast.tv
Opening Session AMIA 2025 Informatics Summit
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Will Townes @willtownes.bsky.social · 31/01/2025
@epigenci.bsky.social makes a pretty convincing case for pseudobulk (as opposed to GLMMs) in multi-sample single cell studies here: doi.org/10.1093/bioi... . #bioinformatics
doi.org
Pseudobulk with proper offsets has the same statistical properties as generalized linear mixed models in single-cell case-control studies
AbstractMotivation. Generalized linear mixed models (GLMMs), such as the negative-binomial or Poisson linear mixed model, are widely applied to single-cell
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Will Townes @willtownes.bsky.social · 28/01/2025
Very proud of CMU Statistics & Data Science PhD candidate Gabrielle Thivierge who just passed her thesis proposal! "Methods for performing and evaluating infectious disease forecasting and nowcasting". Check out her first paper here: arxiv.org/abs/2408.12722
arxiv.org
Does Spatial Information Improve Influenza Forecasting?
Seasonal influenza forecasting is critical for public health and individual decision making. We investigate whether the inclusion of data about influenza activity in neighboring states can improve poi...
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Will Townes @willtownes.bsky.social · 01/11/2024
Cool #Rstats package for wastewater-based #epidemiology adrian-lison.github.io/EpiSewer/ #infectiousdisease
adrian-lison.github.io
Estimate Epidemiological Parameters from Wastewater Measurements
What the package does (one paragraph).
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Will Townes @willtownes.bsky.social · 29/08/2024
Spatiotemporal variability of the pepper mild mottle virus (PMMoV) biomarker in #wastewater : a new preprint with CMU Stats PhD student Anna Rosengart and @wastewaterscan.bsky.social collaborators arxiv.org/abs/2408.12012
arxiv.org
Spatio-Temporal Variability of the Pepper Mild Mottle Virus...
Since the start of the coronavirus-19 pandemic, the use of wastewater-based epidemiology (WBE) for disease surveillance has increased throughout the world. Because wastewater measurements are...
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Will Townes @willtownes.bsky.social · 29/07/2024
Mixed Poisson distributions are useful in modeling count data (eg negative binomial is Poisson mixed with gamma). But did you know the mixing distribution can actually include negative values? Read all about it here: arxiv.org/abs/2407.17614 #probability #statistics
arxiv.org
Mixed Poisson families with real-valued mixing distributions
Mixed Poisson distributions provide a flexible approach to the analysis of count data with overdispersion, zero inflation, or heavy tails. Since the Poisson mean must be nonnegative, the mixing...
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Will Townes @willtownes.bsky.social · 18/07/2024
New preprint: "Exponential tilting of subweibull random variables". arxiv.org/abs/2407.11386 Comments welcome! #probability #statistics
arxiv.org
Exponential tilting of subweibull distributions
The class of subweibull distributions has recently been shown to generalize the important properties of subexponential and subgaussian random variables. We describe alternative characterizations...
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Will Townes @willtownes.bsky.social · 18/03/2024
If I am interested in prediction intervals and am comfortable with a parametric model, what are the pros and cons of conformal prediction as opposed to bootstrapping?
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