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Carine Meignin 🪰🦠🧬🌈

@cmeignin.bsky.social
1.2K followers 1.3K following 17 posts

Biologist #UniversityofStrasbourg Interested in #RNA sensing, nucleic acids, cyclic nucleotids and everything about #Drosophila... ibmc.cnrs.fr/en/laboratoire/m3i-en/…

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Reposted by Carine Meignin 🪰🦠🧬🌈
Robin Allshire 🇮🇪 🇪🇺✊🏿 ⬆️ Zak’s favourite nucleosome: K9me @allshire-lab.bsky.social · 09/04/2026
Very upsetting to hear the sad news of Greg Hannon’s passing. I always enjoyed our far too few conversations we had over the years. He had an interesting and insightful perspective on any science being discussed. He will be missed. www.cruk.cam.ac.uk/news/in-memo...
cruk.cam.ac.uk
In Memoriam: Professor Greg Hannon (1964–2026) - Cancer Research UK Cambridge Institute
Greg was already a world-renowned scientist when appointed Director, and for the community, he was a visionary leader, a cherished mentor, and a singular force of nature whose influence shaped the research landscape.
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Reposted by Carine Meignin 🪰🦠🧬🌈
Serge Abiteboul @abiteboul.com · 15/12/2025
Myriam Maumy-Bertrand, École des Hautes Études en Santé Publique, aborde l’évolution de l’analyse des données de santé à l’heure de l’IA. L’interview réalisée par Erwan Le Merrer. blogbinaire.larecherche.fr/2025/12/12/d... @blogbinaire Société informatique de France
blogbinaire.larecherche.fr
De l’impact de l’IA sur l’analyse des données de santé - Blog binaire
La Société Informatique de France (SIF) partage sur binaire un cycle d’interviews sur l’impact de l’intelligence artificielle (IA) sur les métiers. Ici  Myriam Maumy-Bertrand, Enseignante-Chercheuse a...
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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · 30/03/2026
🆕 New paper out with Jean-Luc Imler and Rune Hartmann in EMBO journal. We dissect mechanisms of antiviral immunity and how STING is activated by FADD and DREDD during viral infection in Drosophila melanogaster. link.springer.com/article/10.1...
link.springer.com
FADD is recruited to activated STING oligomers to initiate caspase-mediated NF-κB activation in Drosophila melanogaster - The EMBO Journal
STING is an evolutionarily conserved key regulator of innate immunity. In the model organism Drosophila melanogaster, STING activates the NF-κB-like transcription factor Relish, initially characterize...
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Reposted by Carine Meignin 🪰🦠🧬🌈
Université de Strasbourg @unistra.fr · 05/11/2025
Sortir de la vision androcentrée du travail, construite sur des perceptions et des intérêts propres aux hommes, telle est l’utopie que tente de rendre réelle le colloque "Utopies féministes au travail. Réorganiser, redéfinir, abolir", du 6 au 7 novembre avec Ada Reichhart, professeure de sociologie.
savoirs.unistra.fr
Un colloque pour repenser le travail du point de vue des théories féministes
Sortir de la vision androcentrée du travail, construite sur des perceptions et des intérêts propres aux hommes, telle est l’utopie que tente de rendre réelle le colloque « Utopies féministes au travai...
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Reposted by Carine Meignin 🪰🦠🧬🌈
Iannacone Lab @iannaconelab.bsky.social · 18/10/2025
Join us for this exciting meeting! @embo.org Workshop "Pathogen Immunity and Signalling", 8-12 June, 2026, Leiden, The Netherlands meetings.embo.org/event/26-pat...
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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · 14/10/2025
Managed to submit the ANR PRC on time… fingers crossed! ⬇️
media.tenor.com
a man is dancing on a dance floor in front of a crowd of people .
ALT: a man is dancing on a dance floor in front of a crowd of people .
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Reposted by Carine Meignin 🪰🦠🧬🌈
EDRC2025 @edrc2025.bsky.social · 25/09/2025
Three fantastic keynote lectures to kick off #EDRC2025 Lucia Prieto-Godiño @crick.ac.uk the @embo.org sponsored lecture, Romain Levayer @pasteur.fr and Marta Llimargas @ibmb-csic.bsky.social
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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · 07/06/2025
Contrats to Dominique Ferrandon’s team @adrienfranchet.bsky.social
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Reposted by Carine Meignin 🪰🦠🧬🌈
The EMBO Journal @embojournal.org · 06/06/2025
REFEREE 1: “I conclude with a simple, direct statement - this is the best paper I have read all year!” #TransparentPeerReview Co-evolving infectivity and expression patterns drive the diversification of endogenous retroviruses @juliusbrennecke.bsky.social et al www.embopress.org/doi/full/10....
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Reposted by Carine Meignin 🪰🦠🧬🌈
Mark A. Hanson @hansonmark.bsky.social · 03/06/2025
URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯 Any lab using @flybase.bsky.social please donate using the link in post below. This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.
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Reposted by Carine Meignin 🪰🦠🧬🌈
Fillip Port @crisprflydesign.bsky.social · 26/05/2025
Why use #CRISPR in #Drosophila when RNAi works so well? Because for some genes well is not good enough. Check out new preprint from the lab demonstrating a role for Vps15 in Wingless trafficking. Something that was missed in several RNAi screens. www.biorxiv.org/content/10.1...
Images from the linked preprint showing Wingless stainings in the Drosophila wing imaginal disc. Targeting vps15 with two indepependent RNAi lines (paper also shows the same with a third line) does not result in a phenotype. In contrast, targeting vps15 with two independent sgRNA constructs and Cas9 results in strong accumulation of Wingless protein in perturbed cells.
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Reposted by Carine Meignin 🪰🦠🧬🌈
Anne Straube @anne.mechanochemistry.org · 17/05/2025
Looking forward to the Physics within the Cell workshop on 16th June. Join if you want to discuss molecular motors and intracellular transport with me. More info here: iop.eventsair.com/pwtc2025/
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Reposted by Carine Meignin 🪰🦠🧬🌈
Sternberg Lab @sternberglab.bsky.social · 15/05/2025
1/10 Today in @science.org in collaboration with the Liu group we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells. drive.google.com/file/d/1I-Ub...
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Reposted by Carine Meignin 🪰🦠🧬🌈
Mark A. Hanson @hansonmark.bsky.social · 16/05/2025
📣 #Drosophila news! 🪰 The AMP mutant lines from Hanson et al. (bit.ly/eLifeHanson) & the many isogenic immunity strains generated by @lmvteixeira.bsky.social & @brunolemaitre.bsky.social groups are now in @vdrc-flies.bsky.social! Find the 40 DrosDel Immunity Panel strains in VDRC library DD-Im ⬇️
shop.vbc.ac.at
Search results for: 'DrosDel Immunity panel'
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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · 15/05/2025
📣 Junior PI Opportunity Join CNRS Strasbourg to lead cutting-edge research on host-pathogen interactions in insects 🪰 450k€ package | Drosophila, RNA, immunity IBMC + Labex NetRNA network 📅 Apply by June 30, 2025 🔗 ibmc.cnrs.fr/en/laboratoi... #RNA #Insects #Drosophila #NetRNA #Immunity #JobAlert
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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · 08/05/2025
Checkout our last paper about Dicer-2 interactome in vivo dx.plos.org/10.1371/jour... #RNAi #Dicer #Drosophila
dx.plos.org
In vivo Dicer-2 interactome during viral infection reveals novel pro and antiviral factors in Drosophila melanogaster
Invertebrates rely mainly on RNA interference (RNAi) as a key defense mechanism against viral infections. The central protein of this process is an enzyme called Dicer-2, which senses and processes vi...
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Reposted by Carine Meignin 🪰🦠🧬🌈
bioRxiv Developmental Biology @biorxiv-devbio.bsky.social · 03/04/2025
An intercellular metabolic relay for brain sparingin Drosophila www.biorxiv.org/content/10.1101/202…
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Reposted by Carine Meignin 🪰🦠🧬🌈
Daryl Gohl @darylgohl.bsky.social · 22/03/2025
Hey fellow Drosophila researchers - if you haven't heard, the UMGC is offering ultra low-cost genome sequencing! See here to learn more: z.umn.edu/UMGC-MOSS #Dros25
University of Minnesota Genomics Center Model Organism Sequencing Service Flyer. $25 for a 30x Drosophila genome.
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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · 03/03/2025
Application for Master in Integrative Biological Sciences (iBioS) - Apply on MonMaster before March 24th. Details on the flyer. imcbio.unistra.fr/imcbio-train...
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Reposted by Carine Meignin 🪰🦠🧬🌈
Lucie Etienne @lucievirevolte.bsky.social · 07/02/2025
We are looking for a #postdoc to discover cell-autonomous innate immune antiviral factors in mammals, based on newly-identified defense of prokaryotes! #EvoCure #comparativeImmunology #virology Please share @inserm.fr @ciri-lyon.bsky.social @cnrsbiologie.bsky.social ciri.ens-lyon.fr/teams/lp2l/j...
ciri.ens-lyon.fr
Postdoc position in comparative immunology and virology — Centre International de Recherche en Infectiologie
A 1-year renewable postdoctoral researcher position is available in our lab (PI: Lucie ETIENNE, CIRI, ENS-Lyon) to discover new antiviral cell-autonomous innate immune factors in mammals, based on new...
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Reposted by Carine Meignin 🪰🦠🧬🌈
RNA Society @rnasociety.bsky.social · 04/02/2025
We are pleased to announce registration for RNA 2025 - the 30th Annual Meeting of the RNA Society - is now open! www2.rnasociety.org This year’s meeting will be held at the beautiful Town and Country Resort & Convention Center in sunny San Diego, California, USA from May 27th - June 1st, 2025.
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Reposted by Carine Meignin 🪰🦠🧬🌈
Kurianlab @kurianlab.bsky.social · 05/02/2025
www.cell.com/cell/fulltex... @marvintanenbaum.bsky.social Fantastic study by the Tanenbaum lab
cell.com
Long-term imaging of individual ribosomes reveals ribosome cooperativity in mRNA translation
Ribosomes cooperate through transient collisions to ensure efficient translation.
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Reposted by Carine Meignin 🪰🦠🧬🌈
Mark A. Hanson @hansonmark.bsky.social · 30/01/2025
ECR fellowship for 2 years abroad. Excellent funding & offers the chance to build your own research direction. 📣 I have a non-model #Drosophila system ripe for collaboration - it's got a balancer chromosome, so GAL4/UAS becomes feasible. #EvolBio questions with functional genetics! Happy to chat.
royalsociety.org
Newton International Fellowships | Royal Society
This fellowship is for non-UK scientists who are at an early stage of their research career and wish to conduct research in the UK.
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Reposted by Carine Meignin 🪰🦠🧬🌈
Sorek Lab @soreklab.bsky.social · 23/01/2025
Our paper out @CellCellPress: Structure guided discovery of viral proteins that inhibit host immunity Congrats Erez Yirmiya, Azita Leavitt, Gil Amitai, our collaborators at the Kranzusch lab, and coauthors A 🧵 1/10 www.cell.com/cell/abstrac...
cell.com
Structure-guided discovery of viral proteins that inhibit host immunity
Large-scale, structure-guided computational pipeline sifts through millions of phage proteins to identify those that bind and antagonize host immune proteins. Detected proteins are shown to inhibit no...
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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · 17/01/2025
📢Job alert We have two postdoctoral positions available, starting in Spring 2025. These positions are part of research funded by an ERC Advanced Grant, focused on exploring evolutionary immunology (Evo-Immuno). #Postdoc #InnateImmunity Do not hesitate to contact us. ibmc.cnrs.fr/en/laboratoi...
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Reposted by Carine Meignin 🪰🦠🧬🌈
Marco Hein @marco.heinlab.org · 14/01/2025
Time to share our organelle proteome paper out in @cellcellpress.bsky.social: doi.org/nzwz We created a spatial map of human cells using organelle immunoprecipitation at scale. Locate your fav protein among the 7,600 we mapped across 19 subcellular compartments: organelles.sf.czbiohub.org/ 1/3 🧪
Graphical abstract of the Organelle Profiling paper, showing the workflow:
Endogenously tagged organelle library;
Native IP proteomics;
Data-driven graph clustering;
resulting in a subcellular proteome map with
more than 7,600 proteins localized across 19 subcellular compartments.
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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · 13/01/2025
📢Job alert Are you interested in Drosophila genetics, insects, innate immunity, evolution? We are offering an exciting Group Leader position within the NetRNA consortium (labex-netrna.cnrs.fr/presentation...) See below for more information and do not hesitate to contact us.
europeandrosophilasociety.org
Junior group leader position | European Drosophila SocietyHome
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Reposted by Carine Meignin 🪰🦠🧬🌈
Kasia Siudeja @ksiudeja.bsky.social · 13/01/2025
Calling all Junior(-ish) Drosophila Investigators 📣📣📣 Join us in June for the JEDIs Resurection : flies-jedi.github.io/projects/202... ✅presentations from participants, ✅panel on publishing (with fantastic guests) ✅plenty of time for socializing Register asap to help us with the first headcount
flies-jedi.github.io
Junior European Drosophila Investigators | JEDI meeting 2025
first post COVID19 meeting --REGISTER before Feb.28
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Reposted by Carine Meignin 🪰🦠🧬🌈
François Leulier @francoisleulier.bsky.social · 06/12/2024
Drosophila and Lactiplantibacillus plantarum in the spotlight (again), what a wonderful model (disclaimer I am biased ;-) ). Congrats Will and team! www.science.org/doi/10.1126/...
science.org
A conserved bacterial genetic basis for commensal-host specificity
Animals selectively acquire specific symbiotic gut bacteria from their environments that aid host fitness. To colonize, a symbiont must locate its niche and sustain growth within the gut. Adhesins are...
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Reposted by Carine Meignin 🪰🦠🧬🌈
Mark A. Hanson @hansonmark.bsky.social · 08/11/2024
ICYMI: we wrote a book. It's a free PDF, but you can also get a physical copy just in time for the holidays. Probably. I dunno. We don't actually get money from it. This was a labour of love by Hannah & Bruno. Also I helped. Stocking stuffer idea: USB loaded with The #Drosophila Immunity Handbook 🪰
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Reposted by Carine Meignin 🪰🦠🧬🌈
Harmit Singh Malik @harmitmalik.bsky.social · 11/11/2024
Abstract submissions for Fly meeting in San Diego 2025 close soon. If you or your trainees are planning to attend, please send in your abstracts to maximize chances of being selected for a platform presentation: genetics-gsa.org/drosophila-2...
urldefense.com
Abstract Submission - 66th Annual Drosophila Research Conference
Visit our website to learn more.
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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · 29/08/2024
Glad to share our latest review on innate antiviral immunity in animals with Joao Marques & Jean-Luc Imler www.sciencedirect.com/science/arti...
sciencedirect.com
An evolutionary perspective to innate antiviral immunity in animals
Viruses pose a significant threat to cellular organisms. Innate antiviral immunity encompasses both RNA- and protein-based mechanisms designed to sens…
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Reposted by Carine Meignin 🪰🦠🧬🌈
bioRxivpreprint @biorxivpreprint.bsky.social · 14/04/2024
Antiviral RNA interference targets viral transcripts but not genomes of RNA viruses in Drosophila melanogaster www.biorxiv.org/content/10.1101/202…
biorxiv.org
Antiviral RNA interference targets viral transcripts but not genomes of RNA viruses in Drosophila melanogaster https://www.biorxiv.org/content/10.1101/2024.04.10.588985v1
RNA interference (RNAi) mediated by the small interfering RNA (siRNA) pathway is a major antiviral m
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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · 11/04/2024
Congratulations to Jean-Luc IMLER for @ERC_Research Advanced Grants! Let's have fun on exciting Evo-immuno's project . #ERCAdG #unistra, #CNRS, #IBMC @unistra.fr
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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · 26/02/2024
⚠️ Junior chair position - BIOLOGY OF HOST-PATHOGEN INTERACTIONS BEYOND VERTEBRATES #M3i #labexNetRNA labex-netrna.cnrs.fr/2024/02/23/j...
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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · 30/01/2024
Portrait of Lihua Li - IMCBio Phd student in our lab. imcbio.unistra.fr/welcome-to-i...
imcbio.unistra.fr
Welcome to IMCBio - PhD students 2023-2024 - Part IV
A portrait of our new IMCBio doctoral researchers, young students who have just joined our programme: Théo Markezic and Jules Lihua Li
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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · 24/01/2024
⚠️ Assistant Professor position in Virology #JoaoMarques, #Jean-Luc Imler, @unistra.fr
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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · 28/12/2023
Please to share our data about Dicer-2 interactome in vivo.
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Mohamed-Ali HAKIMI @hakimi.bsky.social · 20/12/2023
franceuniversites.fr/actualite/co...
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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · 20/12/2023
Our last review on evo-immuno. "Evolutionary immunology to explore original antiviral strategies" doi.org/10.32942/X2D...
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Buzz Baum @buzzbaum.bsky.social · 30/11/2023
Ever wondered how eukaryotic cells got their nucleus? If so, check out Anja and my new hypothesis article - which builds on the ‘inside-out model of eukaryogenesis’: journals.asm.org/doi/10.1128/...
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Karim Majzoub @karimaj.bsky.social · 16/11/2023
Major discovery by the Marrafini lab ! t.co/H05iCNc8Cm
t.co
Bacterial cGAS senses a viral RNA to initiate immunity - Nature
Staphylococcus CdnE03 cyclase recognizes structured RNA molecules produced by staphylococcal phages, triggering cyclic oligonucleotide production and, thereby, bacterial cell death—a mechanism of an...
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