Cells undergo membrane remodeling in response to the environment to perform specific functions. Now, a cytometry-based method with immune cell biomarker analysis captures variations in plasma membrane...

A new study published in Nature Chemical Biology by researchers from SciLifeLab and Karolinska Institutet has developed a method for measuring the physical properties of cell membranes in thousands of...

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Summary: TMEM30A loss disrupts membrane lipid asymmetry, increasing phosphatidylserine exposure, membrane dynamics and surface remodeling, linking flippase dysfunction to immune cell interactions.

Nature Nanotechnology, Published online: 06 August 2026; doi:10.1038/s41565-026-02236-8Membrane-permeant, environment-sensitive nanosensors enable high-throughput, multiparametric quantification of membrane order and mitochondrial potential, revealing immune-cell-specific remodelling and lipid-metabolic dysfunction in atherosclerosis.

Membrane-permeant, environment-sensitive nanosensors enable high-throughput, multiparametric quantification of membrane order and mitochondrial potential, revealing immune-cell-specific remodelling an...

Describing conformational changes in biomolecules using molecular dynamics simulations requires defining an appropriate low-dimensional mathematical d…

dynaMIET enables simultaneous measurement of lateral diffusion and vertical membrane fluctuations in live cells.

SciLifeLab researchers Maliheh Mehrshad and Camilla Engblom are appointed Wallenberg Academy Fellows, and receive five-year basic research grants.

Lange et al. identify a lipid droplet quality control pathway in which FSP1 safeguards stored neutral lipids from lipid peroxidation, thereby preventing the induction of ferroptosis.

A detailed map of the developing human heart, showing different groups of cells and how they interact in fetal heart development, have been published by a team led by SciLifeLab and KTH Royal Institut...

An approach combining bioorthogonal chemistry with genetically encoded fluorogen-activating proteins enables subcellular imaging of phospholipids and glycans, as well as the visualization of lipid tra...

Labeling the plasma membrane for advanced imaging remains a significant challenge. For time-lapse live cell imaging, probe internalization and photobleaching are major limitations affecting most membr...

Selective serotonin reuptake inhibitors (SSRIs) are often prescribed during pregnancy. Yet, epidemiological studies associate in-utero SSRI exposure with neurodevelopmental disorders, such as autism a...

Size and shape are critical discriminators between molecular species and states. We describe a microchip-based high-throughput imaging approach offering rapid and precise determination of molecular pr...

This work challenges a major assumption in cell biology by showing that lipid bilayers can have drastically different phospholipid abundances between their two leaflets. This lipid abundance asymmetry...

The synthesis of life from non-living matter has captivated and divided scientists for centuries. This bold goal aims at unraveling the fundamental pr…

Single particle profiling (SPP) is a unique methodology to study nanoscale bioparticles such as liposomes, lipid nanoparticles, extracellular vesicles, and lipoproteins in a single particle and high t...