Sign in

Andrey Klymchenko

@aklymchenko.bsky.social
251 followers 181 following 32 posts

CNRS senior researcher @unistra, @cnrs, @BrightSens Diagnostics, @AstraNICE. Working on fluorescent probes, organic nanoparticles, biomembranes, biosensing & bioimaging. #StandwithUkraine

PostsRepliesMedia
Andrey Klymchenko @aklymchenko.bsky.social · 23/09/2026
Pre-print alert: we are thrilled to report on rhodamine-derived ratiometric molecular rotor for ratiometric sensing of viscosity in mitochondria. Thanks to co-authors O. Kharchenko and P. Didier! @cnrs.fr, @unistra.fr and @agencerecherche.bsky.social. BioRxiv link: www.biorxiv.org/content/10.6...
0153
Andrey Klymchenko @aklymchenko.bsky.social · 04/06/2026
Trilled that our work on reaction-based nanosensor of neurotransmitters is on the cover @jacs.acspublications.org ! Lock-and-key molecular recognition of dopamine inside lipid nanoreactor triggers a reaction leading to fluorescence turn-on of the nanosensor. @erc.europa.eu @cnrs.fr @unistra.fr
071
Andrey Klymchenko @aklymchenko.bsky.social · 05/05/2026
We thank @cnrs.fr for highlighting our work on artificial receptors for detection of neurotransmitters that just came in @jacs.acspublications.org @erc.europa.eu @cnrs.fr @unistra.fr
052
Andrey Klymchenko @aklymchenko.bsky.social · 30/04/2026
Happy to share our paper in @jacs.acspublications.org on a concept of reaction-based sensing of neurotransmitters driven by a molecular recognition in a lipid nanoreactor. Congrats and thanks to co-authors! @ERC_Research, @unistra.fr @cnrs.fr. pubs.acs.org/doi/10.1021/...
pubs.acs.org
Molecular Recognition-Driven Reaction-Based Sensing of Catecholamines in a Lipid Nanoreactor
Reaction-based sensing is a rapidly expanding principle in the design of fluorescent probes. Although effective for sensing highly reactive species, it is less suitable for more complex small molecule...
0175
Andrey Klymchenko @aklymchenko.bsky.social · 16/04/2026
An immense honor to receive CNRS Silver medal 2026! I would like to thank my team @unistra.fr @cnrs.fr for their hard work and all our collaborators, Kyiv University for the solid education, and @cnrs.fr for providing me the opportunity to realize my dreams! Merci ! Thank you! Дякую!
3226
Andrey Klymchenko @aklymchenko.bsky.social · 01/09/2025
Just out in Nanoscale: we found cooperative effects in DNA-functionalized polymeric nanoparticles, important for biosensing & diagnostics. Congrats & thanks to Paraskevi Gaki & startup BrightSens Diagnostics. @unistra.fr, @cnrs.fr, @bpifrance-officiel.bsky.social, #iLab pubs.rsc.org/en/content/a...
161
Andrey Klymchenko @aklymchenko.bsky.social · 18/08/2025
Our review on light-harvesting nanomaterials for energy transfer & biosensing is out in Adv Mater! We analyzed literature on optical materials mimicking nature – chlorophyll in plants. Thanks & congrats to co-authors: Deep Biswas & Pascal Didier! advanced.onlinelibrary.wiley.com/doi/full/10....
161
Reposted by Andrey Klymchenko
Gasser Group @gassergroup.bsky.social · 24/07/2025
Ready to fly back with @aklymchenko.bsky.social to Paris! Thanks to @faseborg.bsky.social and the organisers for the fantastic event!
0102
Andrey Klymchenko @aklymchenko.bsky.social · 17/06/2025
Great news: I received ERC Advanced grant #ERCAdG @erc.europa.eu CaptuRel! It aims at intelligent nanomaterials undergoing bioinspired cycle of capture and photorelease of bioactive molecules for sensing and controlling (bio)chemical gradients. Thanks to my Team, @cnrs.fr and @unistra.fr!
0494
Reposted by Andrey Klymchenko
LabMINT @labmint.bsky.social · 12/06/2025
Today it is the MINT Day! A good occasion to share science and good moments together. We are really happy to welcome @aklymchenko.bsky.social to open this beautiful day! Thank you very much again for coming ☺️.
042
Andrey Klymchenko @aklymchenko.bsky.social · 28/05/2025
It was a great experience to participate in JCS2025 conference on supramolecular chemistry. Thanks @iwonanieren.bsky.social et al for the invitation and organization of this wonderful event!
061
Andrey Klymchenko @aklymchenko.bsky.social · 08/05/2025
Bürgenstock Conference by @swisschemistry.bsky.social was a truly amazing meeting with brilliant lectures and leading researchers in chemistry: @klanglab.bsky.social, JL Mascarenas, R Buller, @olallalab.bsky.social, D Hilvert, etc. It was an honor to present our work. A big thank to the organizers!
2141
Andrey Klymchenko @aklymchenko.bsky.social · 29/04/2025
New preprint: we introduce peptide-functionalized fluorescent polymeric nanoparticles with stealth properties due to rather short polysarcosine peptides for targeting proteins on cell surface. Congrats to co-authors! @cnrs.fr @unistra.fr @agencerecherche.bsky.social www.biorxiv.org/content/10.1...
1105
Andrey Klymchenko @aklymchenko.bsky.social · 14/04/2025
We revisited our #MemBright toolbox and report anionic cyanine membrane probes with improved properties that enable in vivo imaging of neurons in mice brain. Congrats & thanks to co-authors! Just out Anal. Chem. @acs.org : pubs.acs.org/doi/10.1021/... @cnrs.fr @unistra.fr @lmumuenchen.bsky.social
1214
Andrey Klymchenko @aklymchenko.bsky.social · 11/04/2025
New preprint alert: we found cooperative effects in DNA-functionalized polymeric nanoparticles, important for biosensing and diagnostics applications. Congrats and thanks to co-author Paraskevi Gaki. @unistra.fr, @cnrs.fr, @bpifrance-officiel.bsky.social, #BrightSens www.biorxiv.org/content/10.1...
biorxiv.org
Cooperative effects in DNA-functionalized polymeric nanoparticles
DNA-functionalized nanoparticles (NPs), called as spherical nucleic acids (SNA), attract strong attention due to their unique properties and numerous applications. In particular, DNA-functionalized dy...
062
Andrey Klymchenko @aklymchenko.bsky.social · 07/04/2025
The cover (frontispiece) for our recent article on artificial receptor for neurotransmitter dopamine is finally out in @angewandtechemie.bsky.social. Thanks to Jurga Valanciunaite for the artwork! Congratulations and thanks to the co-authors! @unistra.fr @cnrs.fr @agencerecherche.bsky.social
161
Reposted by Andrey Klymchenko
CBM CNRS UPR4301 @cbm-upr4301.bsky.social · 22/03/2025
Packed room yesterday for a wonderful seminar from @aklymchenko.bsky.social from @cnrs.fr @unistra.fr #Fluorescence for #biomembranes #lipids #proteins cbm.cnrs-orleans.fr/wp-content/u...
cbm.cnrs-orleans.fr
022
Andrey Klymchenko @aklymchenko.bsky.social · 28/02/2025
A deep dive into magic of biomembrane organization thanks to brilliant talk by @leventallab.bsky.social at PSL Chemical Biology meeting in Paris, @institutcurie.bsky.social, @cnrs.fr
181
Andrey Klymchenko @aklymchenko.bsky.social · 20/02/2025
We thank @cnrs.fr for highlighting our work on the artificial receptor for dopamine, recently published in @angewandtechemie.bsky.social, in their news portal: www.insb.cnrs.fr/fr/cnrsinfo/... @cnrsbiologie.bsky.social @unistra.fr @cnrs-alsace.bsky.social
insb.cnrs.fr
Vers une détection ciblée des neurotransmetteurs : un récepteur artificiel pour la dopamine
Les neurotransmetteurs ont un rôle clé dans le fonctionnement du cerveau et peuvent servir de biomarqueurs pour de nombreuses maladies neurologiques.
070
Reposted by Andrey Klymchenko
Erdinc Sezgin @sciezgin.bsky.social · 19/02/2025
New paper out 🎇 It has been 13 years since @owenlabuob.bsky.social and co. published a stellar protocol on how to measure membrane order with smart probes! Since then, there has been new dyes, imaging modes and biology! We wrote a protocol for Nature Protocols: www.nature.com/articles/s41...
nature.com
Measuring plasma membrane fluidity using confocal microscopy - Nature Protocols
Membrane fluidity is a crucial feature in understanding cellular physiology. This protocol describes a robust pipeline for measuring plasma membrane fluidity using confocal imaging and new environment...
17323
Andrey Klymchenko @aklymchenko.bsky.social · 14/02/2025
It is my first Bluesky post: I am thrilled that our work on MemGraft probes for “permanent” fluorescent labelling of plasma membranes is finally out in JACS Au! We established a concept of lipid-directed covalent labeling of plasma membranes. Open access article: pubs.acs.org/doi/10.1021/...
58516