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Reposted by Agustín Mangiarotti

Max Planck Institute of Colloids & Interfaces (MPICI) @mpici.bsky.social · 29/09/2026

Under a microscope, biomolecular condensates look like tiny droplets. But what exactly is inside them? 🧫 A new paper in Advanced Science presents a label-free approach combining Raman spectroscopy and spectral phasor analysis to map the chemical composition of biomolecular condensates in situ. ⬇️⬇️

The picture shows first author Elias Sabri looking through a microscope in the lab. Using Raman spectroscopy, the research team can see the composition of tiny condensate droplets. Credit: MPIKG

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Reposted by Agustín Mangiarotti

Dimova Lab @dimovalab.bsky.social · 03/09/2026

This review with Agu @mangiarotti.bsky.social 🙏on a topic close to my heart -membranes&condensates- came out some time ago.Only after receiving the printed issue,I realized it's on the journal cover. It does not have much to do with plants, but droplets on thin surfaces is kind of what it is about.

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Agustín Mangiarotti @mangiarotti.bsky.social · 09/08/2026

New mini-review out ⚡🧬 Together with Natalia Wilke we critically compare the methods used to measure condensate electric properties, highlight the unexplored membrane-condensate interface and close with some open questions in the field. doi.org/10.1016/j.bb...

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Agustín Mangiarotti @mangiarotti.bsky.social · 20/07/2026

📢 Segunda Reunión Nacional de Condensados Biomoleculares y Organelas Sin Membrana 📍 Instituto Leloir 📅 27–28 agosto 2026 🎟️ Gratis ⚠️ Resúmenes hasta el 30 de julio → QR #LLPS #Condensados #RNA

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Agustín Mangiarotti @mangiarotti.bsky.social · 15/05/2026

🧪🇦🇷 Excited to share our latest paper done together with Natalia Wilke, just out in Soft Matter! The take-home message: anchor lipids deserve to be treated as active membrane components when interpreting protein- and condensate-membrane interactions. doi.org/10.1039/D6SM...

doi.org

NTA-Ni lipids affect membrane phase behavior and fluorescence of lipid-like dyes

The nitrilotriacetic acid group coordinated with nickel, NTA(Ni), is the standard chelator for purifying fusion proteins containing poly-histidine tags. The development of lipids with NTA(Ni) headgrou...

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Agustín Mangiarotti @mangiarotti.bsky.social · 15/04/2026

Take a look at our lastest review: "Phase separation across membranes and condensates in cell organization and function," done together with @dimovalab.bsky.social now available in @nature.com Reviews Cell.Mol.Biol. You can read the full review here: doi.org/10.1038/s415... @mpici.bsky.social

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Reposted by Agustín Mangiarotti

Dimova Lab @dimovalab.bsky.social · 13/02/2026

How do biomolecular condensates🫧 interact with membranes? We show that dielectric permittivity contrast between coexisting phases directly governs condensate wetting behavior. 👉 preprint: bit.ly/4qBmVRx Permittivity matters.🧪🫧

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Agustín Mangiarotti @mangiarotti.bsky.social · 09/11/2025

It was my pleasure to present at the SAIB Lipids Symposium for the first time. I had very enriching discussions about the role of membranes and condensates in cell biology!

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Reposted by Agustín Mangiarotti

Dimova Lab @dimovalab.bsky.social · 06/08/2025

1/3 📢 New work from our lab 📢 We uncover a unifying dielectric principle for biomolecular condensates! 💦Contrary to intuition, we find that it is not a condensate’s absolute polarity, but the permittivity contrast with its surroundings, that governs its affinity for membranes. #GUV #condensates

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Reposted by Agustín Mangiarotti

Biophysical Society @biophysicalsoc.bsky.social · 23/03/2025

Join the Membrane Structure and Function Subgroup will be hosting a webinar on Tuesday, March 25 at 11:00 AM ET. The presentations will explore recent breakthroughs, foundational concepts, and future directions in membrane biophysics. Register here: buff.ly/YOAPVID

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Reposted by Agustín Mangiarotti

Dimova Lab @dimovalab.bsky.social · 21/03/2025

1/8 Exciting new work with Agu @mangiarotti.bsky.social @mpici.bsky.social ! 🚀 Our latest study explores how lipid packing and cholesterol regulate the interaction of biomolecular condensates with membranes. It turns out, it’s not just about membrane phase. Packing is the key! 🧵👇 rdcu.be/eelLq

rdcu.be

Lipid packing and cholesterol content regulate membrane wetting and remodeling by biomolecular condensates

Nature Communications - Membrane lipid packing, influenced by cholesterol, lipid chain length, and saturation, regulates the affinity of biomolecular condensates, enhancing their interactions with...

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