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Job Boekhoven

@boekhovenlab.bsky.social
1.2K followers 405 following 53 posts

Prof. In Systems Chemistry trying synthesize life

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Reposted by Job Boekhoven
Mesoscopic Physics of Life (MPoL) @m-pol.bsky.social · 06/08/2026
🚨 New preprint! From protein & RNA condensates to synthetic coacervates and DNA nanostars, vacuoles (dilute pockets inside droplets) show up everywhere. 🫧 We explain when and why they form. 🔬🧫 📄 arxiv.org/abs/2607.25743 w/ @boekhovenlab.bsky.social sky.social @kgoepfrich.bsky.social
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Job Boekhoven @boekhovenlab.bsky.social · 11/08/2026
1/ Nature builds astonishing things by burning fuel — muscles contract, cells divide, materials heal — and never settles into equilibrium while doing it. Our field has spent a decade building synthetic versions of this. New review 🧵
advanced.onlinelibrary.wiley.com
Chemically Fueled Systems Chemistry Across Length Scales
Chemically fueled reaction cycles regulate processes through single and multiple catalytic sites on the molecular and assembly scale. This gives rise to unique kinetically controlled properties/funct...
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RSC MASC @rsc-masc.bsky.social · 16/12/2025
The 2025 RSC MASC Supramolecular Chemistry Award 🏆, our most senior award, goes to Prof Job Boekhoven @boekhovenlab.bsky.social. Congratulations, Job! Thanks @cellpress.bsky.social for sponsoring the award! #MASC2025 #RSC_MASC
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Job Boekhoven @boekhovenlab.bsky.social · 11/11/2025
I’m happy to share Hector Soria Carrera and Leonie Kauling’s recent work in Chem by @cellpress.bsky.social! A 🧵 below: www.cell.com/chem/fulltex...
cell.com
Primitive genotype-phenotype coupling in fuel-dependent synthetic cells with an autocatalyst
A challenge in the de novo synthesis of life is coupling genotype with phenotype. To achieve this, we use fuel-dependent synthetic cells that host a low-fidelity replicator. This replicator increases ...
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Giacomo Bartolucci (he) @gbart.bsky.social · 15/11/2025
Active droplets are fundamental in cell biology and origin of life. With Jonathan Bauermann, @boekhovenlab.bsky.social, Frank Jülicher, and @m-pol.bsky.social, we show that a critical transition influences their size, morphology, ripening and division propensity journals.aps.org/prx/abstract...
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Job Boekhoven @boekhovenlab.bsky.social · 11/11/2025
I’m happy to share Hector Soria Carrera and Leonie Kauling’s recent work in Chem by @cellpress.bsky.social! A 🧵 below: www.cell.com/chem/fulltex...
cell.com
Primitive genotype-phenotype coupling in fuel-dependent synthetic cells with an autocatalyst
A challenge in the de novo synthesis of life is coupling genotype with phenotype. To achieve this, we use fuel-dependent synthetic cells that host a low-fidelity replicator. This replicator increases ...
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Job Boekhoven @boekhovenlab.bsky.social · 06/11/2025
I am over the moon! Thank you so much @rsc-masc.bsky.social! Our work has been a group effort by the entire BoekhovenLab and alumni!
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Job Boekhoven @boekhovenlab.bsky.social · 06/11/2025
Freshly published: "Primitive genotype-phenotype coupling in fuel-dependent synthetic cells" Amazing work and a critical step towards synthetic life by Hector Soria and Leonie Kauling. A thread will follow soon: t.co/9LfrnVYzoq
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Max Planck School Matter to Life @mattertolife.bsky.social · 25/07/2025
How to build life from non-living components? Or perhaps a blueprint of #MatterToLife! syntheticcell.eu/a-recipe-for... Check out the recent study from @boekhovenlab.bsky.social and @hniederho.bsky.social, @tum.de www.cell.com/chem/fulltex...
syntheticcell.eu
A recipe for synthetic cells: non-biological components, a pinch of evolution and then... life?
The Boekhoven Lab recently engineered a cell-like system capable of producing offspring, a key prerequisite for Darwinian evolution.
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Reposted by Job Boekhoven
European Synthetic Cell Initiative @syncelleu.bsky.social · 28/07/2025
The @boekhovenlab.bsky.social aims to build life from non-living components using #evolution. We look back at one of the group's recent results: the engineering of cell-like systems capable of producing offspring, a key prerequisite for Darwinian evolution #syncell syntheticcell.eu/a-recipe-for...
syntheticcell.eu
A recipe for synthetic cells: non-biological components, a pinch of evolution and then... life?
The Boekhoven Lab recently engineered a cell-like system capable of producing offspring, a key prerequisite for Darwinian evolution.
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Reposted by Job Boekhoven
João Borges @joao-borges.bsky.social · 06/06/2025
🗣️ @boekhovenlab.bsky.social is Associate Professor in the Bioscience Department at the @tumunich.bsky.social 🇩🇪 🎯 His research focuses on #molecular #selfassembly and #non-#equilibrium #chemically fueled #supramolecular #assemblies towards #synthetic #life from the bottom up 👌 👉 Do not miss it!
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Giulio Ragazzon @giuliosflask.bsky.social · 05/06/2025
Pumping molecules against a gradient without a pump? Back-to-back with @boekhovenlab.bsky.social, we describe minimal systems that use chemical energy to transport molecules against a concentration gradient. It started with a little shock!🧵 Us: shorturl.at/smQNF Job's team: shorturl.at/zftps
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Job Boekhoven @boekhovenlab.bsky.social · 30/05/2025
Check out Monika's work published in @cp-chem.bsky.social! We’ve engineered synthetic cells that emerge, grow, and produce offspring autonomously, powered by chemical fuel. A significant stride towards synthetic life! www.sciencedirect.com/science/arti...
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Job Boekhoven @boekhovenlab.bsky.social · 25/04/2025
How can a cell control the size of its organelles? Excited to share a mechanism to control droplet size we recently found. a 🧵 www.nature.com/articles/s41...
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Mesoscopic Physics of Life (MPoL) @m-pol.bsky.social · 19/03/2025
Our group Mesoscopic Physics of Life is now on BlueSky. Hopefully no more strange and unwanted messages ... 😆
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Technische Universität München @tum.de · 12/03/2025
Our university is among the top 20 universities in the world for the first time in both #NaturalSciences and #engineering & #technology in the QS World University Rankings by Subject: go.tum.de/639382 🎉 #QSWUR #SubjectRankings #HigherEducation 📷A. Eckert
go.tum.de
TUM among the top 20 worldwide in natural sciences and engineering
In the QS World University Rankings by Subject, TUM is among the top 20 universities in both natural sciences and engineering & technology.
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Bayerische Akademie der Wissenschaften (BAdW) @badw.de · 28/02/2025
#JungesKolleg: Die neuen Mitglieder stehen fest! Christoph Heilig @lmumuenchen.bsky.social, Maik Luu @Uniklinik Würzburg, Carolin Müller @fau.de, Robert J. Mayer @tum.de und Charlotte Wendland @lmumuenchen.bsky.social 👉 tiny.badw.de/rPTXJE Willkommen in der BAdW! Foto: @wolf-bild.bsky.social
Kollegiatinnen und Kollegialen des Jungen Kollegs der BAdW
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Job Boekhoven @boekhovenlab.bsky.social · 27/02/2025
Check out the video highlight of our recent work! youtube.com/shorts/MCJEb...
youtube.com
It looks like life, but… | Headline Science
YouTube video by American Chemical Society
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Job Boekhoven @boekhovenlab.bsky.social · 07/02/2025
It’s out!😃 2 years ago, I organized a workshop with @WebersGroup and @KGoepfrich on how to build Life. We discussed with leading scientists by day and wrote up our discussions in the eves. The "Roadmap Towards Synthetic Life" is now out in Chem! www.sciencedirect.com/science/arti...
sciencedirect.com
A roadmap toward the synthesis of life
The synthesis of life from non-living matter has captivated and divided scientists for centuries. This bold goal aims at unraveling the fundamental pr…
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Job Boekhoven @boekhovenlab.bsky.social · 05/02/2025
Just arrived in the beautiful Tarragona. Excited to give a lecture at the amazing ICIQ tomorrow. iciq.org/event/regula...
iciq.org
Regulating molecular assembly with chemical fuels— Spinning ribbons, dissipative structures, and an approach towards synthetic life - ICIQ
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Job Boekhoven @boekhovenlab.bsky.social · 05/02/2025
Excited to give a lecture this Friday at the University of Barcelona. More info here: dqio.ub.edu
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TUM Institute for Advanced Study @ias-tum.bsky.social · 09/01/2025
📣Open Call for Fellowships: International scientists who would like to work closely with scientists @tumuenchen.bsky.social and visit us for extend periods can still be nominated until 18 February! More information: ias.tum.de/ias/programs... Open Call: ias.tum.de/ias/news-eve...
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TUM Institute for Advanced Study @ias-tum.bsky.social · 09/12/2024
This week's #WednesdayCoffeeTalk: “Converting chemical energy into motion” by @boekhovenlab.bsky.social! Online at 1 pm - DM us for Zoom info! ias.tum.de/ias/news-eve...
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Job Boekhoven @boekhovenlab.bsky.social · 04/12/2024
All the hard work done by @pablozambrano.bsky.social!
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Job Boekhoven @boekhovenlab.bsky.social · 04/12/2024
Now published in JACS! Pablo found an easy way to divide fatty acid-based protocells. Simplicity first: All you need is to add carbodiimide as fuel! pubs.acs.org/doi/full/10....
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Pablo Zambrano @pablozambrano.bsky.social · 29/11/2024
I am excited to share our latest publication in JACS: "Chemically Driven Division of Protocells by Membrane Budding" I am grateful to all my amazing coauthors for their incredible teamwork @boekhovenlab.bsky.social Read it: pubs.acs.org/doi/10.1021/... #protocells #chemistry #originoflife #JACS
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Kerstin Göpfrich @kgoepfrich.bsky.social · 24/04/2024
We are looking for two #postdocs to join us: 1) @ERC_Research funded position in the context of RNA origami, cryoEM, synthetic cells, directed evolution; 2) A position in the excellence cluster @Cluster3DMM2O at the interface of chemistry & biology. Please share and get in touch!
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Kerstin Göpfrich @kgoepfrich.bsky.social · 15/07/2024
Last year we met with about 60 scientists for 2 weeks to discuss what it means to synthesize life. Here is the summary of our discussion: chemrxiv.org/engage/chemrxiv/articl… We hope it represents diverse views and serves as a roadmap towards...
chemrxiv.org
A roadmap towards the synthesis of Life
The synthesis of life from non-living matter has captivat...
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Job Boekhoven @boekhovenlab.bsky.social · 26/11/2024
It finally arrived! Excited to dig in! @saraimari.bsky.social
Book with the title life as no one know it.

LIFE AS
NO ONE KNOWS IT
THE PHYSICS OF LIFE'S
EMERGENCE
SARA IMARI
WALKER
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Job Boekhoven @boekhovenlab.bsky.social · 22/11/2024
Accepted! Soon, in your favorite American chemistry journal🥳!
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Alex Blokhuis @alexblokhuis.bsky.social · 21/11/2024
I made a starter pack for the Systems Chemistry community: go.bsky.app/VULkeAC I haven't found everyone yet, so I will update it regularly. Drop a message if you're in #systemschemistry but not listed yet. #chemistry #chemsky @hermanslab.bsky.social @yannickgeiger.bsky.social
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Stephan Hacker @stephanhacker2.bsky.social · 18/11/2024
Great to see so many new people here! Explore Starter Packs to get started! I made one of scientists with a focus on #ChemBio, #Chemistry, (Chemical) #Proteomics and #DrugDiscovery: bsky.app/starter-pac... As well as a short version of the 25 most recommended accounts: bsky.app/starter-pac... (1/8)
bsky.app
Scientists to follow
Join the conversation
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Job Boekhoven @boekhovenlab.bsky.social · 18/11/2024
Hey all! I'm just checking in at BlueSky and excited to see the recent surge in activity. ❤️ these cute raining droplets if you want me to follow you. (notice the oscillation?) Follow me if ur interested in systems chem, droplets, self-assembly, synthetic life, non-equilibrium systems, and more!
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