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Institut Necker Enfants Malades

@inem-necker.bsky.social
232 followers 65 following 91 posts

Cutting-edge research in molecular & cellular metabolism, immunology, and beyond. Discover our work driving innovation in health and disease. www.institut-necker-enfants-malades…

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Reposted by Institut Necker Enfants Malades
Manvendra Singh @manusingh.bsky.social · 28/09/2026
1/8 Proud and super thrilled to share our preprint, “A single-nucleus regulatory atlas links transposons to adult hippocampal neurogenesis.”, led by Umut, Fede, and Souad, the FIRST from our #RETROGEN lab @inem-necker.bsky.social . www.biorxiv.org/content/10.6... shrt thread on what we found 🧵
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Journal of Clinical Investigation @jci.org · 15/09/2026
Cilia–to–basement membrane signaling initiates cystogenesis in the kidney doi.org/10.1172/JCI1... The Cover features work by Mazloum et al. @inem-necker.bsky.social showing basement membrane remodeling drives cyst formation in autosomal dominant kidney disease
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Institut Necker Enfants Malades @inem-necker.bsky.social · 29/09/2026
Pour la Fête de la Science 2026, l’INEM vous accueille pour une journée de découverte avec des ateliers conçus pour éveiller votre curiosité scientifique ! Pour en savoir plus : lnkd.in/eZVvR2st 👉 Samedi 10/10, 10h - 16h30 📍 Institut Necker - Enfants Malades, 160 rue de Vaugirard, Paris 15e
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Institut Necker Enfants Malades @inem-necker.bsky.social · 08/09/2026
🧑‍🔬 Don’t miss out the review in @cp-immunity.bsky.social from @venteclefn.bsky.social team on metabolic, obesity and cancer! Learn more about the IMMEDIAB team at INEM: tinyurl.com/529wysnc
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Institut Necker Enfants Malades @inem-necker.bsky.social · 07/09/2026
🔬 New publication, now out in #ScienceImmunology led by Mathieu Deygas in Pablo Vargas team, shows that Adaptive motility enables neutrophils to rapidly navigate confined capillaries 📰 To read the article: tinyurl.com/52vxuhmp
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Institut Necker Enfants Malades @inem-necker.bsky.social · 04/09/2026
La publication "Immunometabolic endotypes define distinct clinical trajectories in type 2 diabetes" dans @cp-cellmetabolism.bsky.social de l'équipe @nicolasven.bsky.social a été mise en avant par un communiqué de presse de l'Inserm. 💡Pour en savoir plus sur l'équipe IMMEDIAB : tinyurl.com/47hwzxmu
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Institut Necker Enfants Malades @inem-necker.bsky.social · 01/09/2026
🔬 New publication from the @philipmour.bsky.social team with with Stamatia Gioftsidi and Takuto Hayashi at INEM in @cp-devcell.bsky.social on how "Postnatal Pax7-expressing limb cells are multipotent and generate non-myogenic lineages that persist into adulthood"
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Institut Necker Enfants Malades @inem-necker.bsky.social · 31/08/2026
👏 Congratulations to @venteclefn.bsky.social team for their new publication in @cp-cellmetabolism.bsky.social about immunometabolic endotypes defining distinct clinical trajectories in type 2 diabetes!
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Reposted by Institut Necker Enfants Malades
Kidney International @kidneyint.bsky.social · 10/08/2026
Non-HLA antibodies worsen the histological phenotype and prognosis of antibody mediated rejection in kidney allografts doi.org/10.1016/j.kint.2026.06.031 #NephSky #MedSky #OpenAccess @inserm.fr @inem-necker.bsky.social @uzleuven.bsky.social
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Institut Necker Enfants Malades @inem-necker.bsky.social · 06/08/2026
🧪 New publication from @fabiolaterzi.bsky.social team at INEM entitled "Non-HLA antibodies worsen the histological phenotype and prognosis of antibody mediated rejection in kidney allografts" in @kidneyint.bsky.social Read it here: tinyurl.com/mtmww249
tinyurl.com
Non-HLA antibodies worsen the histological phenotype and prognosis of antibody mediated rejection in kidney allografts
Antibody-mediated rejection (AMR) remains a leading cause of kidney allograft failure, with both HLA and non-HLA antibodies implicated in its pathogenesis. The contribution of non-HLA antibodies (non-...
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Institut Necker Enfants Malades @inem-necker.bsky.social · 05/08/2026
New research now out in Nature Cell Biology, led by Nathaniel F. Henneman in Ganna Panasyuk team, shows that nuclear class 3 PI3K co-activates fasting-specific chromatin remodelling. Read the article here: tinyurl.com/4h4vybsb Learn more about it and about the first author: tinyurl.com/2pdbjdk7
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Institut Necker Enfants Malades @inem-necker.bsky.social · 04/08/2026
Congratulations to @marco-pontoglio.bsky.social, Julien Diana, @delevoyecedric.bsky.social, Pierre Isnard, @auroreclaudetaupin.bsky.social, Anne Jamet, @esegura-lab.bsky.social, @aminetoubal.bsky.social, Nicolas Venteclef, Jean-François Gauthier, Laurence Arbibe and @mario-pende.bsky.social!
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Institut Necker Enfants Malades @inem-necker.bsky.social · 31/07/2026
🧪 New publication from the @fabiolaterzi.bsky.social team with @olivieraubert.bsky.social and @danyanglicheau.bsky.social at INEM on how "Impaired thymic function is independently associated with an increased risk of posttransplant infections in kidney recipients"
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Institut Necker Enfants Malades @inem-necker.bsky.social · 30/07/2026
🔬 Don't miss out the new publication in @jcellsci.bsky.social from the MEMBRANICs lab at INEM!
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Reposted by Institut Necker Enfants Malades
Institut Imagine @institutimagine.bsky.social · 24/07/2026
🔬 How do ADPKD cysts form? A JCI study by @hkd-l.bsky.social at Institut Imagine & Frank Bienaimé's group @inem-necker.bsky.social shows: without polycystin-1, the tubule sleeve gets softer, not stiffer. This loosening lets the tube expand. A new therapeutic target! 👏 📄 jci.org/articles/vie...
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Institut Necker Enfants Malades @inem-necker.bsky.social · 22/07/2026
📅 SAVE THE DATE | 2026 INEM Prestige Lecture Series From 1 to 4 December 2026, INEM will welcome Professor Fiona Watt, @embo.org Director and an internationally recognised leader in stem cell biology. 📍 INEM : 160 rue de Vaugirard, 75015 Paris More details on our website: tinyurl.com/kp2z4ybv
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Institut Necker Enfants Malades @inem-necker.bsky.social · 20/07/2026
👏 A huge congratulations to Guillaume Canaud on being awarded the 2026 Mendel Medal, an award recognising his significant work on rare diseases linked to mutations in the PIK3CA gene and on the development of innovative treatments for patients! @eshg.bsky.social
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Institut Necker Enfants Malades @inem-necker.bsky.social · 17/07/2026
New research now out in Cell Death & Disease from @natureportfolio.nature.com, led by Véronique Baud in @mario-pende.bsky.social team, shows that the alternative NF-kB RelB subunit is a novel critical sensor of lipid metabolism to promote tumor development.
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Institut Necker Enfants Malades @inem-necker.bsky.social · 15/07/2026
New research now out in Cellular & Molecular Biology Letters, led by Edouard Le Guillou in Ganna Panasyuk team, shows that restoration of lysosomal membrane integrity in cell models of Pompe disease depends on fatty acid synthase and its product palmitic acid. tinyurl.com/ytu86hj9
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Institut Necker Enfants Malades @inem-necker.bsky.social · 13/07/2026
New research now out in @jci.org, led by Manal Mazloum in @fabiolaterzi.bsky.social team, shows that cilia to basement membrane signalling is a biomechanical driver in models of autosomal dominant polycystic kidney disease tinyurl.com/5ahn88ns
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Institut Necker Enfants Malades @inem-necker.bsky.social · 17/04/2026
📢 INEM Friday Seminar Series At INEM Auditorium 2 Today, Zayna Chaker from the Institute of Functional Genomics of Lyon will present her work at the INEM seminar series "The puzzle of adult brain stem cell coordination: A functional and evolutionary perspective" Details here➡️ tinyurl.com/5xmnjkpn
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Reposted by Institut Necker Enfants Malades
Institut Imagine @institutimagine.bsky.social · 09/04/2026
🧫 Wrapping up today's fantastic MAGIC seminar is @manusingh.bsky.social (@inem-necker.bsky.social). His talk: "Single-Cell Mapping of the Reawakening of Ancient Foes in Ageing Disorders." A deep dive into the molecular & cellular mechanisms of Alzheimer. Thanks to all speakers & see you next week! 🧪
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Institut Necker Enfants Malades @inem-necker.bsky.social · 10/04/2026
📢 INEM Friday Seminar Series At INEM - Auditorium 3 Today, Marat Yusupov, from IGBMC, Strasbourg, France, will present his work at the INEM seminar series "Study of ribosome structure for the development of drugs" Details here ➡️ www.institut-necker-enfants-malades.fr/node/4474
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Institut Necker Enfants Malades @inem-necker.bsky.social · 20/03/2026
📢 INEM Friday Seminar Series Today, Robert E. Schwartz, from Weill Cornell Medical College, New York, USA, will present his work at the INEM seminar series "Vascular Identity, Stromal Diversity, and the Challenge of Building a Bioartificial Liver" Details here ➡️ tinyurl.com/szfbjmdc
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Institut Necker Enfants Malades @inem-necker.bsky.social · 20/03/2026
Retour sur la retraite de l'INEM de ces 2 derniers jours près de Fontainebleau Les membres de l'INEM se sont réunis pour des conférences scientifiques… et vulgarisées 🎤 et pour des activités ludiques🎉 👏 Bravo aux présentateur·ices Et merci aux organisateur·rices et sponsors pour cet événement !
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Institut Necker Enfants Malades @inem-necker.bsky.social · 16/03/2026
Le 6 mars 2026, Fabiola Terzi, directrice de l’Institut Necker Enfants Malades, a reçu la Légion d'honneur des mains de Gérard Friedlander. Une reconnaissance qui honore un parcours et les valeurs d’ouverture portées par l’INEM. Plus d'information sur le site de l'INEM : tinyurl.com/3ssxkc2b
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Institut Necker Enfants Malades @inem-necker.bsky.social · 13/03/2026
Aujourd'hui vendredi 13 mars, l'invité du Friday Seminar à l'INEM était Aude Bernheim, chercheuse de l'Institut Pasteur. Invitée par la cellule égalité professionnelle de l'INEM, son séminaire s'intitulait "Ce que le féminisme fait découvrir à la biologie" Plus d'info ici : tinyurl.com/55jmhnh6
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Institut Necker Enfants Malades @inem-necker.bsky.social · 05/03/2026
📢 INEM Friday Seminar Series 📅 March 6th 📍 INEM Auditorium 3 Today, Mercedes Ricote, from the Centro Nacional de Biotecnología of Madrid, will present the INEM seminar series "Mother´s milk drives maturation of heart metabolism" Details here ➡️ www.institut-necker-enfants-malades.fr/node/4444
institut-necker-enfants-malades.fr
Mercedes Ricote | INEM
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Institut Necker Enfants Malades @inem-necker.bsky.social · 27/02/2026
📢 Paris Postdocs Seminar 📅 March 5th 📍 INEM Room 4 (-1) Next week, Alexandre Pierga from @institutimagine.bsky.social will present the @parispostdocs.bsky.social "Loss of MTPAP disrupts mtRNA processing causing upregulation of type I interferon signaling" ➡️ tinyurl.com/4stwnnu7
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Institut Necker Enfants Malades @inem-necker.bsky.social · 27/02/2026
📢 INEM Friday Seminar Series 📅 February 27th 📍 INEM Auditorium 3 Today, Gioacchino Natoli from the European Institute of Oncology, Milan will present for the INEM seminar series "Control of genic and extragenic transcription in inflammation and cancer" Details here ➡️https://tinyurl.com/3pfa6u29
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Institut Necker Enfants Malades @inem-necker.bsky.social · 19/02/2026
📢 INEM Friday Seminar Series 📅 February 20th 📍 INEM Auditorium 3 Tomorrow, Vassili SOUMELIS from Inserm U976 HIPI will present for the INEM seminar series "Multi-Omic data for patient stratification and personalized medicine in immuno-inflammatory diseases" Details here ➡️ tinyurl.com/jezjvcab
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Institut Necker Enfants Malades @inem-necker.bsky.social · 18/02/2026
📢 Paris Postdoc Seminar 📅 February 19th 📍 INEM Room 4 (-1) Tomorrow, Hugo Barreto from @institutcochin.bsky.social will present the @parispostdocs.bsky.social "Eco-evolutionary dynamics of bacterial strains across Human gut microbiotas" ➡️ tinyurl.com/5p82htud
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Institut Necker Enfants Malades @inem-necker.bsky.social · 12/02/2026
📢 Journée des Fournisseurs/Supplier's Day 📅 February 17th 📍 Institut Necker Enfants Malades Next week, INEM is hosting its Supplier's Day ! Over 20 suppliers available to meet with Necker campus researchers & collaborators all day 👩‍🔬👨‍🔬 Organised by the HappyNEM association ➡️ tinyurl.com/mpekc5tb
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Reposted by Institut Necker Enfants Malades
Institut Jacques Monod @ijmonod.bsky.social · 10/02/2026
📢 Paris Postdoc Seminar 📅 February 17th 📍 Institut Jacques Monod Next week, Maria Laura Rojas ( @inem-necker.bsky.social ) will present the @parispostdocs.bsky.social «Organelle Crosstalk and Mitochondrial Renewal in Metabolic Adaptation to Shear Stress» ➡️ buff.ly/FRRVp5B
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Reposted by Institut Necker Enfants Malades
Bioconf @bioconf.bsky.social · 05/02/2026
Upcoming seminar by Hugo Barreto: If you are interested in meeting with the speaker, please reach at Institut Necker Enfants Malades, Thursday 19 February 2026 at 10:00. More info
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Institut Necker Enfants Malades @inem-necker.bsky.social · 04/02/2026
[PUBLICATION] The @goffinlab.bsky.social lab shows a promising therapeutic strategy to mitigate prostate cancer progression towards CRPC — now out in EMBO Molecular Medicine @embomolmed.org 👏🏼 Co-first authors: Manon Baurès & Anne-Sophie Vieira Aleixo 🔗 link.springer.com/article/10.1...
link.springer.com
Targeting pre-existing club-like cells in prostate cancer potentiates androgen deprivation therapy - EMBO Molecular Medicine
A critical knowledge gap in prostate cancer research is understanding whether castration-tolerant progenitor-like cells that reside in treatment-naïve tumors play a direct role in therapy resistance a...
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Reposted by Institut Necker Enfants Malades
Institut Jacques Monod @ijmonod.bsky.social · 02/02/2026
📢 Paris Postdoc Seminar 📅 February 17th 📍 Institut Jacques Monod Maria Laura Rojas ( @inem-necker.bsky.social ) will present the @parispostdocs.bsky.social «Organelle Crosstalk and Mitochondrial Renewal in Metabolic Adaptation to Shear Stress» ➡️ buff.ly/FRRVp5B
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Institut Necker Enfants Malades @inem-necker.bsky.social · 30/01/2026
[SEMINAR] 🗓️ Join us today, for a #seminar with Henri-Francois RENARD, group leader at Université de Namur. Pr. RENARD will explore the molecular mechanisms of clathrin-independent endocytosis. Don’t miss it! Invited by @membramics-lab.bsky.social
Friday January 30, 2026. Auditorium 3 - 12h00
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Institut Necker Enfants Malades @inem-necker.bsky.social · 28/01/2026
[PUBLICATION] The Coureuil lab shows how MDA phages promote N. meningitidis colonisation by pili variants selection — out in @natcomms.nature.com 👏🏼 First & last authors: Clémence Mouville & Emmanuelle Bille 🔗 nature.com/articles/s41467-025-67441-w 📰 Read more on INEM website: tinyurl.com/mr3j39xr
nature.com
Neisseria meningitidis filamentous phage MDA promotes colonisation by selecting hyperadhesive pili variants - Nature Communications
In Neisseria meningitidis, the filamentous phage MDA is associated with biofilm formation during epithelium colonisation. Here, the authors investigate the relationship between phage MDA infection and...
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Institut Necker Enfants Malades @inem-necker.bsky.social · 15/01/2026
[SEMINAR] 📢 Paris Postdoc Seminar at INEM on Thursday January 22 Maria Lizarralde-Iragorri from @institutimagine.bsky.social will present the @parispostdocs.bsky.social seminar "Investigating Hematopoiesis and Erythropoiesis in Sickle Cell Disease" More info ➡️ tinyurl.com/ykjnp873
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Institut Necker Enfants Malades @inem-necker.bsky.social · 12/01/2026
[PUBLICATION] The Schnupf lab shows how SFB remodel their adhesive tip during development from unicellular to filamentous forms - now out in @natcomms.nature.com 👏🏼 First author: @anaraquelcruz.bsky.social 🔗 nature.com/articles/s41467-025-66892-5 📰 Read more on INEM website: tinyurl.com/yjfvbzu2
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Institut Necker Enfants Malades @inem-necker.bsky.social · 09/01/2026
[PUBLICATION] The MODUL-CF study group reports that CFTR modulators can reverse bronchial dilatations in adolescents with cystic fibrosis @thelancet.com 👏🏼 First author & INEM team leader: Isabelle Sermet-Gaudelus 🔗 doi.org/10.1016/S2213-2600(25)00248-6 📰 More on INEM website: tinyurl.com/3fdk752c
doi.org
Redirecting
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Reposted by Institut Necker Enfants Malades
Manvendra Singh @manusingh.bsky.social · 02/01/2026
Happy new year and 3 more days to apply for Computational biology post doc position in my lab #Paris #transpoosns @inem-necker.bsky.social @institutimagine.bsky.social
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Institut Necker Enfants Malades @inem-necker.bsky.social · 08/01/2026
❄️Bonne année 2026 !❄️Happy New Year!❄️ Un bonhomme de neige s’est invité devant l'INEM pour vous souhaiter le meilleur pour cette nouvelle année☃️ ✨Que vos résultats soient significatifs et que vos contrôles fonctionnent à chaque fois !✨May your results be significant and your controls always work!✨
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Institut Necker Enfants Malades @inem-necker.bsky.social · 19/12/2025
[PUBLICATION] The @membramics-lab.bsky.social team shows how keratin is involved in melanin genome photoprotection at the cell level. 👏🏼 Co-1st authors: Silvia Benito Martinez & @laurasalavessa.bsky.social 🔗 doi.org/10.1038/s415... 📰 Read more on INEM's LinkedIn, and website: tinyurl.com/yr9pntvb
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Institut Necker Enfants Malades @inem-necker.bsky.social · 05/12/2025
[CONGRESS] INEM congratulates Etienne Morel @membramics-lab.bsky.social for contributing to the organization of the SBCF symposium Cell Biology of Eukaryogenesis 2026! 👏 📅 Hybrid format (virtual + in-person) ⏳ Register before Dec 20 🔗 More info on the SBCF website sbcf.fr
sbcf.fr
SBCF
Société de Biologie Cellulaire de France
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Institut Necker Enfants Malades @inem-necker.bsky.social · 03/12/2025
[PUBLICATION] The team of @mathieucoureuil.bsky.social shows how N. meningitidis reshapes host membranes via type IV pili to recruit its own signaling receptors. 👏🏼 Co-1st authors: Audrey Laurent Granger & Kévin Sollier 🔗 doi.org/10.1038/s414... Read more on INEM website: tinyurl.com/2s4fetyh
doi.org
Meningococci drive host membrane tubulation to recruit their signaling receptors - Nature Communications
The adhesion of meningococci to endothelial cells relies on type IV pili, which induce the formation of long tubular structures on the host cell membrane. Here, the authors show that the tubular struc...
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Institut Necker Enfants Malades @inem-necker.bsky.social · 02/12/2025
After a few months away, INEM is back on Bluesky! 📢 Paris Postdoc Seminar on Thursday Alberto Iannuzzo will present the @parispostdocs.bsky.social seminar "Deciphering the mechanisms responsible for the pathogenicity of CDC42 variants identified in autoinflammatory syndromes" ➡️ tinyurl.com/84bsf5ee
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Institut Necker Enfants Malades @inem-necker.bsky.social · 17/07/2025
[PUBLICATION] The @membramics-lab.bsky.social shows how Influenza A virus rewires ER lipid metabolism to promote vRNP egress. 👏🏼 Co-1st authors: Carla Alemany & @julianedagraca.bsky.social journals.plos.org/plosbiology/... w/ @institutpasteur.bsky.social & IPNP @plosbiology.org
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Institut Necker Enfants Malades @inem-necker.bsky.social · 16/07/2025
[PUBLICATION] NEW in @cp-cellreports.bsky.social @julianedagraca.bsky.social et al. show that ER-endosome contacts act as hubs for phagophore formation during starvation. 📖 www.cell.com/cell-reports... @membramics-lab.bsky.social
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