Reposted by Sushil Dubeymyosinactncrazy.bsky.social @myosinactncrazy.bsky.social · 09/09/2026www.pnas.org/doi/10.1073/... Myosin II–independent contraction of actin filaments in membrane nanotubes 052
Reposted by Sushil DubeyBenoit Ladoux @bladoux.bsky.social · 02/09/2026Happy to share our new study @ijmonod.bsky.social on how surface curvature shapes multicellular organization and function. How curvature controls tissue chirality, patterns distinct architectures, and influences myogenic differentiation? www.biorxiv.org/content/10.6... 13210
Reposted by Sushil DubeyBenoit Ladoux @bladoux.bsky.social · 02/09/2026Happy to share our new preprint! We uncover how local force imbalances drive keratinocyte delamination and upward motion, while neighboring cells close the basal layer below. Amazing work from @andreasschoenit.bsky.social! www.biorxiv.org/content/10.6... 13311
Sushil Dubey @dubey837.bsky.social · 31/08/2026How surface curvature shapes muscle tissue architecture: New preprint from our lab shows that myoblasts self-organize into helical structures driven by substrate curvature, revealing a geometric mechanism that also regulates myogenic differentiation. 041
Reposted by Sushil DubeyBenoit Ladoux @bladoux.bsky.social · 22/08/2026Happy to share our new paper @natcomms.nature.com on the role of active nematics on myoblast fusion and myotube growth! www.nature.com/articles/s41... Amazinf work from @dubey837.bsky.social, @yoannletoquin.bsky.social and Aleksandra Ardaševa! 14714
Sushil Dubey @dubey837.bsky.social · 23/08/2026Thrilled to announce that our paper is out in Nat comm! We explored how muscle cells know exactly where to fuse, revealing that extracellular-matrix (ECM) mediated stresses spatially bias myoblast fusion and myotube growth. rdcu.be/fBBcBrdcu.be 0112
Reposted by Sushil DubeyBenoit Ladoux @bladoux.bsky.social · 08/07/2026Thrilled to share our new paper on cell extrusion. A beautiful study with a tremendous amount of data, led by the fantastic @fanny-wodrascka.bsky.social ! www.biorxiv.org/content/10.6... 25113
Reposted by Sushil DubeyBenoit Ladoux @bladoux.bsky.social · 29/04/2026Happy to share our new paper on collective cell dynamics. Great work from Yuan Shen @ijmonod.bsky.social ! Dynamic heterogeneity and hidden fluidity in dense epithelial tissues | Science Advances www.science.org/doi/10.1126/...science.orgDynamic heterogeneity and hidden fluidity in dense epithelial tissuesDensely packed epithelial tissues appear mechanically arrested at tissue scale, but their cells move in subtle, coordinated ways. 04113
Reposted by Sushil DubeySudheer Peneti Ph.D @sudheerpeneti.bsky.social · 14/01/2026My PhD work showed that vimentin is not only a passive marker of EMT, but plays an active role in collective migration, controlling the mechanics of epithelial leader cells. I am grateful to my supervisors, Rene-Marc & Benoit Ladoux, as well as to all the co-authors. www.biorxiv.org/content/10.6... 1164
Reposted by Sushil DubeyFranze Lab @franzelab.bsky.social · 19/01/2026Paper alert: Our study led by @evapillai.bsky.social and @sudimukherjee.bsky.social showing that mechanical properties of the #brain actively shape the molecular landscape during development and #axonpathfinding is finally out! www.nature.com/articles/s41... @pdncambridge.bsky.social @fau.de @MPZPMnature.comLong-range chemical signalling in vivo is regulated by mechanical signals - Nature MaterialsTissue stiffness mediated by Piezo1 is shown to regulate the expression of diffusive guidance cues in the developing Xenopus laevis brain, revealing a crosstalk between mechanical signals and long-ran... 28628
Reposted by Sushil DubeyJulia Eckert @juliaeckert.bsky.social · 14/12/2025Wondering how to control the environment of cells? Check out this insightful #EpithelialMechanics thread by @lhinderling.bsky.social 👇 0244
Reposted by Sushil DubeyBenoit Ladoux @bladoux.bsky.social · 11/11/2025Just out! Our work on active transport in epithelial tissues. Congrats to Huiqiong Wu, Greg Arkowitz and Ranjith Chilupuri in collaboration with C. Duclut and J. Prost! PNAS www.pnas.org/doi/10.1073/... 13712
Reposted by Sushil DubeyBenoit Ladoux @bladoux.bsky.social · 17/09/2025Happy to share our new study @ijmonod.bsky.social and @mpi-scienceoflight.bsky.social with C. Duclut and J. Prost. on forces generated by active fluid transport in epithelia and their role in tissue dynamics. Congrats to Huiqiong Wu, G. Arkowitz and R. Chilupuri! www.biorxiv.org/content/10.1...biorxiv.orgRegulation of epithelial tissue homeostasis by active trans-epithelial transportEpithelia are intricate tissues whose function is intimately linked to mechanics. While mechanobiology has primarily focused on factors such as cell-generated contractility and mechanical properties o... 03619
Reposted by Sushil DubeyBenoit Ladoux @bladoux.bsky.social · 01/08/2025To what extent does crowding modulate diffusion across the cytoplasm? Thrilled to contribute to this study alongside O. Destrian, M. Chabanon, and B. Goyeau! www.biorxiv.org/content/10.1...biorxiv.orgCytoplasmic crowding acts as a porous medium reducing macromolecule diffusionIntracellular transport of macromolecules is crucial for the proper functioning of most cellular processes. Although intracellular crowding is known to strongly alter macromolecule mobility, how cytop... 2387
Reposted by Sushil DubeyMax Planck Institute for the Science of Light (MPL) @mpi-scienceoflight.bsky.social · 16/04/2025Exploring the Frontiers of #Mechanobiology Mechanobiology Conference III, organized by Prof. @bladoux.bsky.social ( #MPZPM), takes place July 6–12, 2025 in Vietnam. Topics include cell signaling, biomaterials & more. 📅 Deadlines: Abstracts – Apr 30 | Reg – Jun 6 👉 icisequynhon.com/conferences/... 099
Reposted by Sushil DubeyLakshmi Balasubramaniam @lakshmib02.bsky.social · 10/04/2025We are excited to share our recent preprint on how tissue spreading guides extracellular matrix changes during early morphogenesis @gurdoninstitute.bsky.social 53817
Reposted by Sushil DubeyBenoit Ladoux @bladoux.bsky.social · 10/04/2025🌿✨ Calling all mechanobiologists, bioengineers, and curious minds! ✨🌿 Join us in Vietnam this year for an unforgettable Conference on Mechanobiology, where science meets culture in one of Southeast Asia’s most vibrant destinations. 📅 06-12 July 📍 Quy Nhon, Vietnam 🔗 icisequynhon.com/conferences/...icisequynhon.comMechanobiology 2025 1145
Reposted by Sushil DubeyBenoit Ladoux @bladoux.bsky.social · 14/03/2025Happy to share our new publication in @naturematerials.bsky.social on mechanical cell competition! Great collaboration between our CAM team, Chavrier's and Doostmohammadi's. Special congrats @luanger.bsky.social, @andreasschoenit.bsky.social, Siavash Monfared! 🎉 www.nature.com/articles/s41... 16933
Reposted by Sushil DubeySara Wickstrom @sarawickstrom.bsky.social · 15/02/2025My lab at the Max Planck Institute for Molecular Biomedicine in Muenster, Germany offers postdoc positions in stem cell mechanobiology. www.mpi-muenster.mpg.de/departments/... drop me an emailmpi-muenster.mpg.deCell and Tissue Dynamics (Wickström) 08064
Reposted by Sushil Dubeyepithelial mechanics fan club @epimechfc.bsky.social · 16/02/2025Tissues are dynamic and investigating cellular mechanical states can be crucial for understanding biological processes. But how to do it? We are @andreasschoenit.bsky.social and @luanger.bsky.social from @bladoux.bsky.social / @rmmege.bsky.social lab highlighting ways to assess tissue stresses. 12213
Reposted by Sushil DubeyBenoit Ladoux @bladoux.bsky.social · 08/01/2025Happy to share our new publication in @naturephysics.bsky.social on life and death of eliminated cells! Great collaboration between our CAM team and Doostmohammadi's. Special congrats @lakshmib02.bsky.social and Siavash Monfared! 🎉 www.nature.com/articles/s41... 17924
Reposted by Sushil DubeyBenoit Ladoux @bladoux.bsky.social · 30/12/2024We have an exciting line-up of speakers for our third Mechanobiology conference in Vietnam from July 6 - 12, 2025. icisequynhon.com/conferences/... 02711
Sushil Dubey @dubey837.bsky.social · 30/11/2024My first post on #bluesky and it's going to be a special one! Our study investigates the role of biomechanics in muscle fusion and differentiation...🧵👇 www.biorxiv.org/content/10.1...biorxiv.orgMechanical stresses govern myoblast fusion and myotube growthMyoblast fusion into myotubes is critical for muscle formation, growth and repair. While the cellular and molecular mechanisms regulating myoblast fusion are increasingly understood, the role of biome... 281