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Berna Sozen

@bernasozen.bsky.social
348 followers 172 following 2 posts

Developmental Biologist, Assistant Professor @Yale @YaleMed | PD Alumni @Cambridge_uni @Caltech | Early Embryogenesis & Stem Cell passionate👩🏻‍🔬 www.sozenlab.org

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Reposted by Berna Sozen
Development @dev-journal.bsky.social · 15/09/2026
In preprints – the embryo, the placenta and lessons from developmental metabolism @bernasozen.bsky.social explores how recent #preprints by Aguilera-Castrejon et al. & Xu et al. reveal metabolic roles for embryonic and extra-embryonic tissues during mid-gestation. doi.org/10.1242/dev....
doi.org
In preprints – the embryo, the placenta and lessons from developmental metabolism
This article discusses the preprinted work of Lokshtanov and colleagues (Lokshtanov et al., 2026 preprint) as well as that of Xu and team (Xu et al., 2026 preprint). As preprints, these works have…
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Reposted by Berna Sozen
Vincent Pasque @pasquelab.bsky.social · 13/08/2026
Delighted to see our book on Stem Cell-Based Human Embryo Models published in Methods in Molecular Biology. link.springer.com/book/10.1007...
link.springer.com
Stem Cell-Based Human Embryo Models
This book covers diverse aspects of stem cell research and exemplifies some of the developments and improvements in the field.
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Reposted by Berna Sozen
Jesse Veenvliet @jesseveenvliet.bsky.social · 09/04/2026
📣 New Perspective out in @natcellbio.nature.com! With an interdisciplinary team of scientists, ethicists & lawyer we propose embedded ethics as a framework for navigating the complex ethics of human stem cell–based embryo models. www.nature.com/articles/s41... Free full text link: rdcu.be/fckmY 🧵
nature.com
A guide to using embedded ethics in human stem-cell-based embryo model research - Nature Cell Biology
This Perspective proposes the use of an integrative embedded ethics approach to evaluate human stem-cell-based embryo models and outlines a nested benchmarking strategy to periodically evaluate their scientific and ethical status.
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Reposted by Berna Sozen
The Vilcek Foundation @vilcekfoundation.bsky.social · 10/02/2026
Check out this article in @science.org featuring our Vilcek Prizewinners: @nucleosomepolice.bsky.social, @takashiakeralab.bsky.social, @amanglik.bsky.social, & @bernasozen.bsky.social! These immigrant scientists are shaping the future of medicine. Read more about their discoveries: vilcek.co/3OxUKFG
vilcek.co
Honoring immigrants in research: The Vilcek Prizes in Biomedical Science
Diverse voices overcome scientific challenges
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Reposted by Berna Sozen
Alex Eve @amjeve.uk · 20/10/2025
Good morning from Generative Biology! @bernasozen.bsky.social starts by taking a closer look at metabolism in early embryogenesis. Learn more about stem cell-based embryo models in her recent @dev-journal.bsky.social Review: doi.org/10.1242/dev.... and interview: doi.org/10.1242/dev....
doi.org
Transitions in development – an interview with Berna Sozen
Berna Sozen is an Assistant Professor in the Department of Genetics at Yale University, USA. Berna's lab studies early mammalian development, metabolism, and maternal–fetal interactions using mouse an...
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Reposted by Berna Sozen
Ali Shariati @ali-shariati.bsky.social · 05/06/2025
Really grateful to @bernasozen.bsky.social and @harrymcnamara.bsky.social for their thoughtful preview of our CRISPRa-programmed embryo model in @cp-cellstemcell.bsky.social. Love the title and the insight. means a lot to us!🙏🏾
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Reposted by Berna Sozen
Development @dev-journal.bsky.social · 08/04/2025
In this Review, @bernasozen.bsky.social, Patrick Tam & Martin Pera summarize how recent studies of embryo models have advanced our understanding of cell state transitions of the pluripotent human epiblast and highlights some key remaining questions: doi.org/10.1242/dev....
Figure 2 Overview of cell state transitions in hPSCs in 2D and 3D embryo models. Embryo illustrations on the left represent the in vivo developmental stages corresponding to the three pluripotency states: naive (yellow), formative/intermediate (light green) and primed (dark green). On the right, the lineages they have the potential to give rise to in stem cell-based embryo models are illustrated. The generation of primordial germ cells (PGCs) from amnion remains to be determined. EXM, extra-embryonic mesoderm; PGCs, primordial germ cells.
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Berna Sozen @bernasozen.bsky.social · 04/04/2025
a real pleasure to write this piece with Martin Pera and Patrick Tam, where we reflect on recent insights and open questions in early human development: doi.org/10.1242/dev....
doi.org
Pluripotent cell states and fates in human embryo models
Summary: This Review summarizes how recent studies of embryo models have advanced our understanding of cell state transitions of the pluripotent human epiblast and highlights some key remaining questi...
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Reposted by Berna Sozen
Virtual Gastrulation Zoom Talks @vgzt2021.bsky.social · 01/03/2025
Get ready for our next western/evening 🌙 session seminar on Thursday! with Loic Le-Goff @loic-legoff.bsky.social (buckling morphogenesis 🪰) and Berna Sozen @bernasozen.bsky.social (🐁 gastrulation) 🗓️ Thursday, March 06th at ⏰ 09:30 PST / 12:30 EST / 17:30 UTC / 17:30 GMT / 18:30 CET
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Reposted by Berna Sozen
canaztekin.bsky.social @canaztekin.bsky.social · 06/01/2025
🚨Why can’t mammals regenerate legs or arms like frog tadpoles or salamanders? Our preprint tackles (part of) this BIG question with surprising findings about oxygen sensing 🔗 www.biorxiv.org/content/10.1... Happy New Year, everyone! 🎉 🐭 vs 🐸 #evodevo #regenerative #cellbio 🧵👇
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Reposted by Berna Sozen
epithelial mechanics fan club @epimechfc.bsky.social · 14/12/2024
Metabolism is a key developmental regulator. In mammalian gastrulation, hexosamine biosynthetic pathway drives epiblast differentiation, while glycolysis guides mesoderm migration and lateral expansion. bsky.app/profile/epim...
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