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Joshua Frenster

@joshifrenster.bsky.social
317 followers 344 following 51 posts

Cell competition in development/gastruloids (postdoc Alfonso Martinez Arias) Previously: adhesion GPCRs in Glioblastoma (PhD Placantonakis Lab NYU) frensterlab.com

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Reposted by Joshua Frenster
DMM Journal @dmmjournal.bsky.social · 03/09/2026
*** Call for papers deadline extended *** Submit your latest #Paediatric #GeneticDiseases paper to be included in our next special issue. The deadline has been extended to 7 December 2026. Find out more today 👇️ tinyurl.com/3b8zscaz
Call for papers - Special Issue - Paediatric Genetic Diseases: Models, Mechanisms and Therapies. Edited by James Amatruda, Ross Cagan and Elaine Mardis. Extended deadline: 7 December 2026.
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Reposted by Joshua Frenster
Science News @scinews.bsky.social · 27/06/2026
Generative artificial intelligence creates delicious, sustainable, and nutritious burgers www.nature.com/articles/s41... #food #AI #LLMs #Burger #Nutrition
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Reese Richardson @reeserichardson.bsky.social · 21/05/2026
@johanduchene.bsky.social @sholtodavid.bsky.social Spent the last hour looking, found ten more apparently manipulated Western blots in Thermo Fisher's antibody verification data (across eight different catalogued products). Thread below. www.thermofisher.com/antibody/pro...
Apparent manipulation in the antibody verification data in Thermo Fisher's online catalog
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Reposted by Joshua Frenster
Roberto Mayor Lab @mayorlab.bsky.social · 16/05/2026
PL retweet. Developmental Biology Course (Quintay). More information: biodesarrollo.unab.cl
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Joshua Frenster @joshifrenster.bsky.social · 09/05/2026
I received close to 200 applications for positions in my new lab and I absolutely underestimated the time it would take to work through everything while evaluating candidates 🫠... But it's also really fun to read so many promising profiles and personal stories!
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Joshua Frenster @joshifrenster.bsky.social · 27/04/2026
🚨Last days to apply!🚨 The Frenster Lab is hiring to study how cell competition is regulated in early embryonic development. We use 3D Gastruloids from multiple species and have exciting crossovers of developmental and cancer biology! Join us at University of Freiburg #cellcompetition #gastruloid
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Reposted by Joshua Frenster
Stem Cell Podcast @stemcellpodcast.com · 15/04/2026
Scientists led by Dr. @joshifrenster.bsky.social at @upf.edu have discovered that cell competition in gastruloids is stage-specific and driven by relative p53 levels during pluripotency exit. 📄 Read more: go.nature.com/41YmuXt 🎙️ Listen now: bit.ly/425e7JH
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i2bcparissaclay.bsky.social @i2bcparissaclay.bsky.social · 17/03/2026
We are looking for outstanding scientists to develop ambitious research programs in molecular and cellular biology, with special interest in multidisciplinary projects and computational biology.More info: www.i2bc.paris-saclay.fr #MolecularBiology #CellBiology #ComputationalBiology #TeamLeaders#I2BC
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Alfonso Martinez Arias @amartinezarias.bsky.social · 04/04/2026
Because #gastruloids allow measurements, they can teach us about quantitative traits. Exploring #CellCompetiion @joshifrenster.bsky.social et al www.nature.com/articles/s41... Biology as a matter of #Genes #Cells and #Numbers but of much that is #NotInTheGenes
nature.com
Mosaic gastruloids reveal a temporal restriction for developmental cell competition - Nature Cell Biology
Frenster et al. utilize mosaic mouse gastruloids as a model of cell fitness and competition, identifying a temporal window between primed pluripotency and early gastrulation during which cell competit...
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Joshua Frenster @joshifrenster.bsky.social · 01/04/2026
🥳 I am happy to share our latest manuscript published in @natcellbio.nature.com We use #Gastruloids to study #CellCompetition during early mammalian development and find not only that this is highly pronounced in our system but also tightly restricted in time. (1/12) www.nature.com/articles/s41...
nature.com
Mosaic gastruloids reveal a temporal restriction for developmental cell competition - Nature Cell Biology
Frenster et al. utilize mosaic mouse gastruloids as a model of cell fitness and competition, identifying a temporal window between primed pluripotency and early gastrulation during which cell competit...
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Ali Seleit @aliseleit.bsky.social · 24/03/2026
Very happy to announce that I will be joining the Faculty of Biology & @cibss.bsky.social at @uni-freiburg.de as an Emmy-Noether funded group leader. We will tackle the molecular and genetic basis of developmental timing and size control using diverse Oryzias species. We are hiring at all levels !
seleit-lab.com
Evo-Devo-Tempo Lab
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Joshua Frenster @joshifrenster.bsky.social · 24/03/2026
The Frenster Lab is here! 🍾 I am so excited to start my #EmmyNoether funded group at @uni-freiburg.de this summer. Our group studies #CellCompetition dynamics during embryonic development using #gastruloids from multiple species. Thanks to the @dfg.de for creating this opportunity! FrensterLab.com
frensterlab.com
Frenster Lab | Cell Competition Dynamics
We study Cell Competition during Embryonic Development using 3D Gastruloids at the University of Freiburg. We view cells as interactive societies in development and cancer. Research, stem cells, Gastr...
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Virtual Gastrulation Zoom Talks @vgzt2021.bsky.social · 25/09/2025
We are excited to announce the first Western VGZT of Season 7! 🎉 🗓️ Thursday, October 2nd ⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET Our speakers: 👉 Antonia Weberling (@a-weberling.bsky.social) 👉 Sanjay Narayanaswamy (@sanjay-n.bsky.social)
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Virtual Gastrulation Zoom Talks @vgzt2021.bsky.social · 08/07/2025
Join the VGZT Eastern KEYNOTE lecture ☀️☕ TOMORROW 🗓️ Wednesday July 09 ⏰ 13:30 IST / 17:00 JST / 8:00 UTC / 10:00 CET Featuring: 1) Maithreyi Narasimha 👉Positioning tissues during Drosophila morphogenesis Jose Silva @josesilvalab.bsky.social 👉From founder cells to organogenesis-stage embryo model
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Reposted by Joshua Frenster
Dr. Peter Walentek (Walentek Lab) @walenteklab.bsky.social · 16/06/2025
Save the date 📅! Our TriNational #devbio #stemcell Meeting 2025 will be held in Freiburg on Sept. 19th. As always, participation is free and talks will be selected from early career scientists. Joun us 😊 Info: devstemcell.org/home @biozentrum.unibas.ch @uni-freiburg.de @igbmc.bsky.social
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Joshua Frenster @joshifrenster.bsky.social · 04/06/2025
Big news! "researchers will be eligible to apply for a Starting Grant immediately after successfully defending their PhD, and at any time within the following ten-year period." #ERC #ERCstarting erc.europa.eu/news-events/...
erc.europa.eu
Changes to the 2026 and 2027 Work Programmes
With the launch of the competitions for grants under ERC Work Programme 2026 in July of this year, several changes to the submission of applications and the evaluation of proposals will apply. The mai...
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Reposted by Joshua Frenster
Gonca Erdemci-Tandogan @goncaerdemci.bsky.social · 09/05/2025
I'm excited to join @pritiagarwal.bsky.social and @tarafinegan.bsky.social as a co-organizer for the International Developmental Mechanics Seminar Series. The series will resume in September 2025, and call for speakers is now open! More info is on our new website: sites.google.com/view/devmech...
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Kristina Stapornwongkul @kstapornwongkul.bsky.social · 16/04/2025
📢 Fresh off the press and featuring new exciting experiments! 🧪 We show how glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signaling - happy to finally share this 😊 doi.org/10.1016/j.st... B2B with @jesseveenvliet.bsky.social lab: doi.org/10.1016/j.st... 🤩
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Joshua Frenster @joshifrenster.bsky.social · 23/03/2025
I'm really grateful for the large turnout of our Gastruloid meeting in Barcelona. Close to 100 researchers from 9 countries. With the gastruloid field expanding, I hope that the community stays this close and that the meeting becomes an annual tradition! #gastruloids #conference
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Alfonso Martinez Arias @amartinezarias.bsky.social · 21/03/2025
The Barcelona #gastruloid meeting has been a blast. A witness to a field that is maturing and a statement of a promise that lurks in its horizon. Thank you @joshifrenster.bsky.social @dias-andre.bsky.social and Ulla Fiuza for the organization, @EMBO, @ERC and the community for support.
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Kristina Stapornwongkul @kstapornwongkul.bsky.social · 20/03/2025
Thrilled to announce that I am looking for a Research Technician/Assistant to join my lab @imbavienna.bsky.social. Please consider applying if you’re enthusiastic about #devbio #stemcells #teamwork and excited to help shaping a new lab! Thankful for any retweet! 🫶 imba.onlyfy.jobs/job/l6u2m980
imba.onlyfy.jobs
Research Technician
IMBA - Institute of Molecular Biotechnology is one of the leading biomedical research institutes in Europe focusing on cutting-edge functional genomics and stem cell technologies. IMBA is located at t...
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Joshua Frenster @joshifrenster.bsky.social · 20/03/2025
First day of our Gastruloid Meeting in Barcelona kicking off with amazing talks and discussion and a room filled with gastruloid enthusiasts! #gastruloids #conference
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gastrulomicslab.bsky.social @gastrulomicslab.bsky.social · 13/03/2025
Excited to share our latest paper in DevCell! We show how EOMES and the SWI/SNF complex collaborate to drive chromatin remodeling, establishing mesoderm and endoderm differentiation potential. Read the full paper here: www.cell.com/developmenta...
cell.com
EOMES establishes mesoderm and endoderm differentiation potential through SWI/SNF-mediated global enhancer remodeling
Schröder et al. describe the molecular functions of the Tbx factor Eomes, which, together with the SWI/SNF chromatin remodeling complex, establishes enhancer accessibility at mesoderm and endoderm (ME...
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Reposted by Joshua Frenster
Acebrón @acebronsp.bsky.social · 26/02/2025
Do you want to illuminate your studies on innate immune responses? Our new biosensor monitors mtDNA from apoptosis, viral infections, other sources of dsDNA and environmental cGAMP. We also show that micro nuclei are poor activators of the #STING response
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Joshua Frenster @joshifrenster.bsky.social · 30/01/2025
Thinking about the Spanish word "anoche", I realized that we forgot the English word "yestereve". Bring back concise words!
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Reposted by Joshua Frenster
Alfonso Martinez Arias @amartinezarias.bsky.social · 26/01/2025
1/3 Embryogenesis requires fit cells. Here, following work from @miguel-torres-1963.bsky.social & @tristanrodriguez72.bsky.social and led by @joshifrenster.bsky.social we develop a #gastruloid model of #CellCompetition www.biorxiv.org/content/10.1... showing it recapitulates much of the embryo 🧵
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André Dias @dias-andre.bsky.social · 13/01/2025
www.biorxiv.org/content/10.1... Here we explore the role of #Wnt and #Nodal signalling during mammalian gastrulation using #gastruloids. Building on the work of many labs, we propose that antagonistic signalling-dependent #modularity in the PS establishes the early mammalian body plan.
biorxiv.org
A temporal coordination between Nodal and Wnt signalling governs the emergence of the mammalian body plan
Nodal and Wnt signalling play an important role in the emergence of the mammalian body plan, primarily by orchestrating gastrulation and primitive streak formation. While the literature suggests that ...
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Reposted by Joshua Frenster
Alfonso Martinez Arias @amartinezarias.bsky.social · 17/12/2024
We've wondered for a while why #gastruloids are so sensitive to initial cell numbers. Here www.biorxiv.org/content/10.1... led by U, Fiuza, we explore this & observe effects of a number of variables on final structure and think what this tells us @ embryogenesis #IInNumbersWeTrust #NotInTheGenes
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Levayer Lab @levayerr.bsky.social · 08/12/2024
For the dev bio crowd : there is a call for junior group leader at Institut Pasteur in Paris and one of the axis covered is related to development. Come and join us in this exciting place and become one of our colleague @devstempasteur.bsky.social Please RT !! research.pasteur.fr/fr/call/call...
research.pasteur.fr
Call for applications 2025 – Creation of new research groups at the Institut Pasteur | Research - Institut Pasteur
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Joshua Frenster @joshifrenster.bsky.social · 04/12/2024
When late science-nights reward you with those types of views, it makes it all worth it!
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Virtual Gastrulation Zoom Talks @vgzt2021.bsky.social · 28/11/2024
Next week, we’re back with two unique development talks: mouse gastruloids 🐭 with Kristina Stapornwongkul and turtles 🐢 with Agáta Horáčková & Barbora Straková. Mark your calendar—you won’t want to miss this! 🗓️ Dec 5, 12:30 EST / 18:30 CET / 17:30 UTC 🕥
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 25/11/2024
We recently uncovered that morphogenetic signals not only read our blueprints, but are key to maintain them, particularly in stem cells. Joint effort of numerous collaborations and the lead of Prof. Sergio Acebrón at @cosheidelberg.bsky.social www.nature.com/articles/s41...
nature.com
Developmental signals control chromosome segregation fidelity during pluripotency and neurogenesis by modulating replicative stress - Nature Communications
Here the authors show that the patterning signals WNT, BMP, and FGF control chromosome segregation fidelity during early lineage specification and neurogenesis, which could provide a rationale for the...
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Reposted by Joshua Frenster
Jase Gehring @skyjase.bsky.social · 14/11/2024
i'm begging y'all to stop reporting centrifuge speeds in RPM. plz stop.
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Joshua Frenster @joshifrenster.bsky.social · 20/11/2024
Let's get the discussion rolling with a starter pack that will grow over time! go.bsky.app/JyvbmXA #gastruloid #stembryo #gastruloids
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Joshua Frenster @joshifrenster.bsky.social · 20/11/2024
🚨 The Gastruloid Meeting will take place in Barcelona, Spain on March 20-21st 2025. Registration will be free but mandatory. Please let us know if you plan on attending, using this link: forms.gle/EtHZukwqgyN6... (Pre-registration is closing soon) Spread the word! #gastruloid #conference
forms.gle
Gastruloid meeting Barcelona 20-21.03.2025
Dear all, The lab of Alfonso Martinez Arias is organizing a gastruloid meeting at the Barcelona Biomedical Research Park (PRBB), in Barcelona (Spain), on March 20th-21st, 2025 (Thursday afternoon and...
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Joshua Frenster @joshifrenster.bsky.social · 19/11/2024
Hello world.
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