Davi Bock’s lab took 21 million images for the fruit fly connectome. Now he wants to apply “this high-throughput flashlight” across biology.

Across animal phyla, odor information is represented in the first olfactory processing center by combinatorial activation of discrete glomeruli. To examine how this organization of olfactory processin...

Mapping the human brain with light

For nearly 150 years, textbooks have described dendritic morphology as optimized for efficient synaptic voltage transfer from spines to the soma, implemented as a tubular design respecting Rall’s 3/2…

Neuronal circuits in the olfactory bulb (OB) perform computations fundamental to pattern classification including a decorrelation and normalization of odor-evoked activity. These computations are medi...

Brains rely on internal models of the world to interpret sensory input and to simulate the future. In the mammalian hippocampal-entorhinal network, environments are represented by cognitive maps that ...

Intelligent behavior requires experience-dependent internal representations of relevant information. We examined representational learning in telencephalic area pDp of adult zebrafish, the homolog of ...

The authors present a dense connectomic reconstruction of a 0.1 mm3 hippocampal CA3 volume and reveal spatial gradients, high convergence and cell-type-selective feedforward inhibition of inputs to py...

The Paul Scherrer Institute PSI is the largest research institute for natural and engineering sciences in Switzerland. We design, build and operate the country’s large-scale research infrastructures a...

Neuroscientist Andreas Schaefer is spearheading a new project to capture the intricacies of the mouse brain using X-rays, bringing researchers closer to a complete map of its neural connections.

Veith et al. show how a fish—Danionella cerebrum—can reliably startle away from sound. It uses the relative phase between particle motion and pressure to infer the direction of sound. This sensorimoto...

Salary for this Role: SLRS: From £45,700 per annum with benefits, subject to skills and experience PLRS: From £55,555 per annum with benefits, subject to skills and experience Job Title: Senior/Princi...

Volume EM and connectome reconstruction of the apical organ of a ctenophore combined with high-speed imaging reveals a neuronal coordination of balancer cilia in the gravisensory organ.

Imaging spotlight: Revealing mouse brain ultrastructure using non-destructive X-ray tomography - News

A large network of interconnected neurons serves as the basis of brain function and of behavior. Methodological advances have enabled the reconstruction of large-scale and even whole-brain connectomes...

A large network of interconnected neurons serves as the basis of brain function and of behavior. Methodological advances have enabled the reconstruction of large-scale and even whole-brain connectomes...

Optimizations of X-ray nanotomography including the choice of resin allows high-resolution imaging of mouse brain tissue, approaching the resolution of volume electron microscopy. Since it does not re...