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Princeton Neuroscience Institute

@princetonneuro.bsky.social
886 followers 77 following 75 posts

Discoveries and developments from the Princeton Neuroscience Institute. Explore our website 🏠: pni.princeton.edu Read recent research stories 📰: linktr.ee/princetonneuro Join our newsletter 📬: eepurl.com/iTAKzI

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Princeton Neuroscience Institute @princetonneuro.bsky.social · 23/09/2026
📢 We’re hiring! PNI is seeking a full-time Lecturer in Computational and Cognitive Neuroscience to teach undergraduate and graduate courses in computational modeling and human cognitive neuroscience. Priority consideration: Nov. 30 Apply: apply.interfolio.com/193741 #NeuroSkyence #NeuroJobs
exterior photo/rendering of the PNI and psychology building
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Princeton Neuroscience Institute @princetonneuro.bsky.social · 10/09/2026
Welcome back, PNI community! Today, we kicked off the new academic year today with lunch, ice cream from the wonderful folks at Melba Ice Creamery, and a lot of "how was your summer?" Good to see everyone again! 🍦☀️
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Princeton Neuroscience Institute @princetonneuro.bsky.social · 04/09/2026
We're hiring! PNI is recruiting an assistant professor of neuroscience working with non-human primates in any area. Review begins Oct 19: apply.interfolio.com/192521 #NeuroJobs #Neuroskyence
photo of PNI and psychology building
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Tatiana Engel @engeltatiana.bsky.social · 19/08/2026
Difficult decisions take time, but can we keep all accumulated evidence in mind long enough to make better choices? We find that working-memory limitations constrain decision-making, and these effects are modulated by dopamine. biorxiv.org/content/10.6... bioRxiv out with Cina Aghamohammadi et al.
biorxiv.org
Working memory limitations and dopamine modulation in probabilistic reasoning
Difficult decisions require gathering evidence over extended periods, placing demands on working memory. Yet, how working memory limitations affect decision-making remains largely unknown. We trained ...
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Andrew Leifer @andrewleifer.bsky.social · 28/08/2026
"American science needs an executive branch constrained by checks and balances" now out in Nature Physics with Andrea Liu, Sidney Nagel and Thierry Emonet. Gift-link: rdcu.be/fCDGE Original: doi.org/10.1038/s415... @natphys.nature.com #physics
rdcu.be
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Annegret Falkner @neurrriot.bsky.social · 30/08/2026
Watching other animals fight is very common across the animal kingdom, so it must be highly adaptive! @dextertsin.bsky.social, Jorge Iravedra-Garcia and I explore some ideas of how animals might learn from this experience www.sciencedirect.com/science/arti...
sciencedirect.com
Watching the watchers: aggression observation as a window into the neural mechanisms and computations underlying social learning
Classic experiments by Albert Bandura more than 50 years ago first illustrated that aggression is shaped not just by innate predisposition but also by…
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Elizabeth Margulis @margulisa.bsky.social · 18/08/2026
How does the brain make meaning when listening to wordless music? 🧵 on our new paper out today in @natcomms.nature.com (1/) www.nature.com/articles/s41...
nature.com
Music evokes shared neural representations of imagined narratives across sensory modalities - Nature Communications
When people listen to music, they often imagine remarkably similar stories. The authors show these shared imaginings selectively rely on stimulus-specific patterns in a set of modality-general brain r...
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Harrison Ritz @hritz.bsky.social · 27/08/2026
Our task-switching paper is now out at Current Biology! www.cell.com/current-biol... We find that that our brains reset to a task-neutral state between trials, providing flexibility when the upcoming task is uncertain. RNNs also learn this strategy, but only when trained to switch tasks.
schematic of how a brain might reset to a neutral state between trials
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eartha mae @endoeartha.bsky.social · 28/08/2026
Extremely proud to share @acara333.bsky.social and my new paper, out today in @cp-neuron.bsky.social, where we develop a new fluorescent reporter of neural responses to estrogen! 🔬 paper 📝: www.cell.com/neuron/fullt... addgene page 🧬: www.addgene.org/254753/ #neuroskyence 🧪 1/10
graphical abstract of the manuscript depicting pink estrogen-sensitive neurons with a subset of their nuclei colored in green. These green nuclei represent estrogen receptor dependent neural gene transcription, tracked via the expression of a destabilized GFP with a 2 hour half-life. At top, in green is shown a cartoon of the neural response to estrogen across two estrous cycles, and below there is a cartoon of a mouse implanted with an optic fiber for in vivo imaging.
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Annegret Falkner @neurrriot.bsky.social · 30/08/2026
In vivo estrogen imaging is here! Construct is up on addgene, and lots of other imaging constructs are currently in validation. Get in touch if you want advice about how to set up. We are happy to help! Thanks so much to @alleninstitute.org and @onemindorg.bsky.social for their support 😍
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Taylor Webb @taylorwwebb.bsky.social · 26/07/2026
I'm recruiting two postdocs (or potentially PhD students) to work on projects at the intersection of cognition, neuroscience, and AI (with a particular emphasis on mechanistic interpretability). Apply here: docs.google.com/forms/d/e/1F... and please share!
docs.google.com
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Dr. Cate Peña @cate-cholamine.bsky.social · 07/08/2026
So proud to have “Early-life stress alters H3K4me1 in VTA to prime stress sensitivity” out now in Neuron! This work spanned Many years and Many people contributed. Huge thanks to @hyejaykim.bsky.social, @ja-balouek.bsky.social, Luke Geiger, and Meaghan Creed www.cell.com/neuron/fullt...
cell.com
Early-life stress alters H3K4me1 in VTA to prime stress sensitivity
Kim, Geiger et al. report that early-life stress increases the chromatin modification H3K4me1 and its enzymatic writer, SETD7, in the ventral tegmental area. They show that this form of epigenetic pri...
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Zhihao Zheng @zhihaozheng.bsky.social · 07/08/2026
Happy to share the CA3 dataset is published. First large-scale dense connectomics from hippocampus. First connectomic dataset imaged in @princetonneuro.bsky.social. A harbinger of many larger datasets to come (for both). doi.org/10.1038/s415... #hippocampus But my personal favorite is (1/2)
doi.org
Hippocampal CA3 connectomics reveals a gradient of mossy fiber inputs and selective feedforward inhibition onto pyramidal cells - Nature Neuroscience
The authors present a dense connectomic reconstruction of a 0.1 mm3 hippocampal CA3 volume and reveal spatial gradients, high convergence and cell-type-selective feedforward inhibition of inputs to py...
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Dr. Cate Peña @cate-cholamine.bsky.social · 29/07/2026
Excited to share this paper led by two undergrads in the lab, out now in Neurobiology of Stress! Temporal reorganization of maternal care during early life stress in mice doi.org/10.1016/j.yn...
doi.org
Redirecting
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Princeton University @princeton.edu · 24/07/2026
21 Innovation Research Grants have awarded by Princeton Engineering in 2026, enabling engineering faculty members to take their research in bold new directions that address critical issues in technology, health and the environment.
bit.ly
Princeton Engineering - Innovation grants could help build a moon base, block food-borne illness, and map the brain
Claire White’s research group is investigating how to make cement from moon rock. This year, her team received support for research on lunar cement from Princeton’s School of Engineering and Applied S...
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Scully Center @scullycenter.bsky.social · 26/07/2026
Congrats Frederick d'Oleire Uquillas and colleagues on their Nature Neuroscience publication regarding cerebellar aging! doi.org/10.1038/s415...
doi.org
Cerebellar aging is spatially heterogeneous and supports cognitive resilience in later life - Nature Neuroscience
The cerebellum ages unevenly, with some regions showing preservation that may help protect the brain from decline. The authors show that large cerebellar volume is associated with stronger cognitive r...
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Princeton Neuroscience Institute @princetonneuro.bsky.social · 23/07/2026
Congratulations to our 2026 SYNAPSE interns on an absolutely fantastic round of oral presentations today as part of the Virtual Leadership Alliance National Symposium! Sparkling cider to celebrate the occasion 🥂
group photo of the 10 SYNAPSE interns in front of the Princeton Neuroscience Institute buildingSYNAPSE interns clinking flutes with sparkling cider to celebrate their successful talks
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Julie Fabre @juliefabre.bsky.social · 18/07/2026
We're launching the PNI Open Science Awards at @princetonneuro.bsky.social, a pilot program to recognize the tools, datasets, and protocols that advance open, reproducible neuroscience with @maxime-beau.bsky.social. This work is foundational to modern neuroscience but rarely gets formal credit.
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The Transmitter @thetransmitter.bsky.social · 17/07/2026
Thank you, Princeton University, for hosting us. It was great meeting with students and sharing more information on @thetransmitter.bsky.social’s offerings, resources and tools. #neuroskyence
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The Transmitter @thetransmitter.bsky.social · 02/07/2026
Neuro Funding Finder helps you find grants, fellowships and funding opportunities for neuroscience research. Filter results by location, career stage and grant type to streamline your search. Explore now: thetransmitter.org/neuroscience... #neuroskyence
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Nathaniel Daw @nathanieldaw.bsky.social · 14/07/2026
Provocative title ftw. (Tho it inspired @kristorpjensen.bsky.social to give a talk titled "planning in the brain: it's not what nathaniel thinks it is")
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Princeton University @princeton.edu · 25/06/2026
Princeton researchers have combined brain cells and advanced electronics into a 3D device that can be programmed to recognize patterns using computational techniques.
bit.ly
Princeton Engineering - New 3D device harnesses living brain cells for computing
Princeton researchers have combined brain cells and advanced electronics into a single 3D device that can be programmed to recognize patterns using computational techniques.
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The Transmitter @thetransmitter.bsky.social · 24/06/2026
NEW! Explore @thetransmitter.bsky.social’s newest tool, Neuro Funding Finder. Discover grants, fellowships and funding opportunities for neuroscience research at all career stages. Find your next funding source and apply, all in one place: thetransmitter.org/neuroscience... #neuroskyence
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Laura Luyten @lauraluyten.bsky.social · 21/06/2026
I've been a bit quiet lately (lots of teaching duties...), but I am glad to share that I will have some academic "me time" for the next few weeks. I will be at the Princeton Neuroscience Institute & Department of Psychology, for a research stay hosted by @nathanieldaw.bsky.social!
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Princeton Neuroscience Institute @princetonneuro.bsky.social · 12/06/2026
What a thrill to have our visiting summer SYNAPSE students get to know returning alums! Thanks to Branson ('18), Jorge ('18), and Mona ('16) for joining us for our SYNAPSE reunion lunch today 🧠
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Princeton University @princeton.edu · 10/06/2026
A team of @princetonneuro.bsky.social researchers has uncovered a clever way to make viral gene delivery safer for the brain, tackling an unexpected side effect caused by the very virus used to deliver research tools.
bit.ly
Making viral gene delivery safer for the brain
By subtly editing the DNA of the workhorse delivery vehicle—the Adeno-Associated Virus (AAV)—scientists have prevented the virus from triggering an innate immune alarm that can damage critical neural ...
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Jesse Gomez @jessegomez.bsky.social · 10/06/2026
New paper from graduate student Fred charting the heterogeneous aging of the human cerebellum and its surprising role in buffering against cognitive decline www.nature.com/articles/s41...
nature.com
Cerebellar aging is spatially heterogeneous and supports cognitive resilience in later life - Nature Neuroscience
The cerebellum ages unevenly, with some regions showing preservation that may help protect the brain from decline. The authors show that large cerebellar volume is associated with stronger cognitive r...
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Jan Lause @janlause.bsky.social · 09/06/2026
Meet Eyewire II: a new connectomic resource for the mouse retina. ~1 mm² of retina at nanometer resolution, with synapses and circuits of ca. 100,000 neurons, plus visual responses from the ~400 neurons shown in the video! Preprint: doi.org/10.64898/202... Data: eyewire.ai 🧠📈 🧠💻🧪 #VisionScience
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Princeton Neuroscience Institute @princetonneuro.bsky.social · 04/06/2026
Welcome to the 2026 PNI SYNAPSE Internship Program cohort! 🧠 Edriana 🧠 Nancy 🧠 Letitia 🧠 Andrew 🧠 Bobby Carl 🧠 Emma 🧠 Leo 🧠 Alex 🧠 Julianna 🧠 Charvi Here's to a summer of great science (and plenty of coffee + Bent Spoon ice cream)!
Group picture of the 2026 PNI SYNAPSE student interns (+ program director on far right).
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Kate Nussenbaum @katenuss.bsky.social · 03/06/2026
How do we predict what’s going to happen next? In a new paper, we @arikahn.bsky.social @licezhang.bsky.social @nathanieldaw.bsky.social @catehartley.bsky.social ask how kids, teens, and adults solve this problem. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Developmental Change in Structure Learning Reflects a Shift From Recency‐Based to Relational Prediction
Children are adept statistical learners, capable of parsing streams of structured input into meaningful units, but the cognitive processes they engage during learning may differ from those of adults...
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Nathaniel Daw @nathanieldaw.bsky.social · 03/06/2026
I have been so excited about this project. In many ways the most surprising thing to me was how seemingly similar the AI-discovered models were to simple ones I thought I understood, even though they fit way better. This means we can also really get what makes them work.
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Princeton Neuroscience Institute @princetonneuro.bsky.social · 01/06/2026
Kicking off the summer with ice cream, ice dola, and get-to-know-you bingo, thanks to our amazing Climate & Inclusion committee🍦
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Andrew Leifer @andrewleifer.bsky.social · 18/05/2026
We're hiring a postdoc to develop and use custom optical instruments for measuring and manipulating neural activity in worms and flies. Please apply via interfolio: apply.interfolio.com/186001
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Dr. Cate Peña @cate-cholamine.bsky.social · 05/05/2026
I’m recruiting a new lab manger! Please pass on to anyone who might be interested, and have them reach out to me once they’ve applied. Photo proof of awesome lab to join research-princeton.icims.com/jobs/21793/r...
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Princeton Neuroscience Institute @princetonneuro.bsky.social · 05/05/2026
Congratulations to PNI graduate student Isha Gore on being honored as an outstanding educator with a Teaching Award by the @princeton.edu Graduate School and McGraw Center for Teaching and Learning!!
Rodney Priestley (right) handing Teaching Award to PNI graduate student Isha Gore (left)
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Princeton University @princeton.edu · 01/05/2026
"As a veteran, I understand what it means to serve the nation. I also think it's important when you're getting an education to always have that service mindset." U.S. Navy veteran Luke Hixson '25 shares how Princeton bridged the gap from the military to medical school — at no cost to him.
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Princeton University @princeton.edu · 01/05/2026
Eight Princeton professors were elected to the National Academy of Sciences this year: Cliff Brangwynne, Chris Chang, Maria Chudnovsky, Jianqing Fan, Sabine Kastner, Sebastian Seung, Daniel Sigman and Christopher Skinner.
princeton.edu
National Academy of Science elects eight Princeton professors
Eight Princeton professors were elected to the National Academy of Sciences this year: Cliff Brangwynne, Chris Chang, Maria Chudnovsky, Jianqing Fan, Sabine Kastner, Sebastian Seung, Daniel Sigman and...
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Princeton Neuroscience Institute @princetonneuro.bsky.social · 30/04/2026
A heartfelt 'cheers' to @sebastianseung.bsky.social and Sabine Kastner from the PNI community on their NAS election! 🍾🥂🎉
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Princeton Neuroscience Institute @princetonneuro.bsky.social · 29/04/2026
🎉 Congratulations to PNI’s Sabine Kastner and @sebastianseung.bsky.social on their election to the @nationalacademies.org! Kastner and Seung are among 8 @princeton.edu faculty recognized in this year’s class 🧠🏆 #NAS163 pni.princeton.edu/news/2026/sa...
pni.princeton.edu
Sabine Kastner and Sebastian Seung elected to the National Academy of Sciences
Princeton Neuroscience Institute (PNI) faculty members Sabine Kastner and H. Sebastian Seung have been elected to the National Academy of Sciences (NAS). Established in 1863 by President Abraham Linco...
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Sam Wang @samwang.bsky.social · 29/04/2026
Princeton-area friends of science! Come out for a discussion with Joshua Weitz, author of Science Matters. What’s happening to research in America? What can be done? Today at 4:00pm, Frist Campus Center 302, here at Princeton. www.princeton.edu/events/2026/...
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Princeton Neuroscience Institute @princetonneuro.bsky.social · 24/04/2026
Big news for @princeton.edu's neural circuit labs! 🔬🧠 Thanks to an Office of the Dean for Research award, we're acquiring a new light sheet fluorescence microscope. Paired with LICONN tissue expansion, it maps axons & synapses at nanoscale resolution.
research.princeton.edu
Transformative equipment awards support four new research capabilities
Four Princeton research teams are receiving funding through the University’s Provost and Dean for Research Transformative Equipment Initiative to acquire state-of-the-art equipment or replace aging…
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Princeton Neuroscience Institute @princetonneuro.bsky.social · 22/04/2026
Welcome to PNI, Class of 2028! 🎉🧠 We're thrilled to officially welcome 50 new Neuroscience majors to the department. We celebrated with the University on Friday and kept the energy going with our inaugural PNI-specific Declaration Day event on Monday with the Princeton Neuroscience Network.
a sign reading: "2028" with orange, black, and gold balloons behind ita banner on a fence reading: "NEURO" with a group of newly declared NEU majors behind it, all wearing their Class of 2028 sweatersPNI Dec Day celebrant filling out a card on why they chose NEU majorPNI dec day celebrants playing a social bingo game
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Sam Wang @samwang.bsky.social · 20/04/2026
Next week here on the @princeton.edu campus: What's the future of science? Guest Joshua Weitz will give an overview of the federal attacks on science. Then we'll have a sitdown conversation on what's ahead, and what we can do. Next Wednesday 4/29 at 4:00pm, Frist Campus Center 302.
Poster of Sam Wang and Joshua Weitz for an event: The Future Of Science: a timely public discussion on the impact of attacks on science and medical research. April 29, 2026, 4:00pm, Frist Campus Center room 302, at Princeton University. Reception to follow.
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Sam Wang @samwang.bsky.social · 09/04/2026
Neuroscience moment: big mammals and little mammals use the same type of "wires" (axons) to send signals across the brain. But little mammals have smaller brains, so does it take less time for them to react? Maybe not! I talk to The Scientist: www.the-scientist.com/how-is-infor...
the-scientist.com
How Is Information Transmitted in Large Animals? | The Scientist
Every organism must be able to respond to stimuli in its environment, but when animal sizes strain the limits of neuron signaling, how do these massive creatures adapt?
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Princeton University @princeton.edu · 06/04/2026
Across the Princeton campus and beyond, groundbreaking biomedical advances are emerging from interdisciplinary partnerships among brilliant scholars — each bringing their individual gifts to the toughest medical questions.
bit.ly
Biomedical research is surging at Princeton University
Across the Princeton campus and beyond, groundbreaking biomedical advances are emerging from interdisciplinary partnerships among brilliant scholars — each bringing their individual gifts to the tough...
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Princeton Neuroscience Institute @princetonneuro.bsky.social · 23/03/2026
Come cheer on PNI graduate student ‪@ed-neuro.bsky.social of the @jessegomez.bsky.social lab this Wednesday (3/25) as she competes as a finalist for the inaugural @princeton.edu Graduate School Three Minute Thesis (3MT) competition! gradschool.princeton.edu/3MT#tab-marc...
gradschool.princeton.edu
Three Minute Thesis
As part of our 125th Anniversary celebration, the Princeton Graduate School is proud to introduce Princeton's first Three Minute Thesis (3MT®) Competition, a globally recognized platform for graduate ...
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Dr. Cate Peña @cate-cholamine.bsky.social · 16/03/2026
This is such a moving spotlight. I’m proud to have had Luke in my lab for his senior thesis! *In the nation's service and the service of humanity*
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Princeton University @princeton.edu · 13/03/2026
Paternal care is rare in mammals, but male African striped mice can be doting fathers. A new @princetonneuro.bsky.social study reveals that social circumstances and genetics drive African striped males to either care for pups or attack them.
bit.ly
The making of doting dads
Depending on social circumstances and genetics, male African striped mice either dote on pups or attack them.
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Forrest Rogers, PhD @forrestdrogers.bsky.social · 05/03/2026
I had the opportunity to write a research briefing for Nature, in which I summarized our recent work in African Striped Mice. It’s a short read for anyone who wants a quick overview! www.nature.com/articles/d41...
nature.com
A genetic switch turns off parental behaviour and drives infanticide in male striped mice
In striped mice, the social environment affects expression of the Agouti gene, which in turn can drive pup-directed hostility.
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Princeton University @princeton.edu · 26/02/2026
“As an athlete, you learn quickly that every teammate brings something different. @eastersealschi.bsky.social taught me to value those differences as strengths and reminded me why I wanted to pursue neuroscience. It showed me that what I study isn’t just science — it’s people.” — Taylor Charles ’26
Taylor Charles sitting on Oval With Points sculptureTaylor Charles running and dribbling the ball during a basketball game
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