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Georg Keller

@georgkeller.bsky.social
691 followers 249 following 62 posts

Neuroscientist studying the mechanisms of psychiatric treatments. apredictiveprocessinglab.org

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Reposted by Georg Keller
Sergiu P. Pasca @sergiuppasca.bsky.social · 16/09/2026
Today in Nature @nature.com, we report a new approach to studying human brain development and modeling disease in vivo. Open article link below 👇
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Georg Keller @georgkeller.bsky.social · 03/08/2026
Discovered in the halls of FMI - I can't quite put into words how delighted this made me...
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Reposted by Georg Keller
Roman Doronin @romodorro.bsky.social · 25/07/2026
How do psychedelics reorganize cortical communication at the circuit level? In our new paper with @georgkeller.bsky.social we look into how the psychedelic DOI breaks down cortical modularity, and map the underlying cortico-cortical and thalamo-cortical mechanisms in mice – a thread 1/10
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Hugo Ladret @therehugolad.bsky.social · 16/04/2026
Thank you Georg! Very happy to have worked on this. Here is a short 🧵 on what ECT-triggered CSD looks like, and why we think it is going to help shape the future of ECT research. (1/12)
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Reposted by Georg Keller
IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 15/04/2026
💡What if we could reboot sick cells? IOB scientists @timayupov.bsky.social, @vmorenojuan.bsky.social and collaborators led by Botond Roska have developed #MitoCatch, a system that delivers healthy mitochondria directly to diseased cells. A step toward precision mitochondrial medicine. Pic©IOB 🧵👇
Targeted mitochondrial delivery: Extracellular donor mitochondria are delivered specifically to neurons via bispecific protein binders.
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Reposted by Georg Keller
Nicole Rust @nicolecrust.bsky.social · 15/04/2026
I've been waiting for this particular flavor of naysayer review (it's in Swedish). TL;DR: Brain research has failed to deliver on its big promises in the past; ergo, we must be wary now too. Indeed. I was inspired to write Elusive Cures ... /1 lakartidningen.se/kultur/recen...
lakartidningen.se
Neurovetenskapens ständigt dyra löften
Enligt författaren till »Elusive cure« står vi på tröskeln till en helt ny era i hjärnforskningen.
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Georg Keller @georgkeller.bsky.social · 15/04/2026
For nearly a century, we believed the therapeutic effect of ECT is the seizure. Our latest research suggests we may have been looking at the wrong event. A thread on why cortical spreading depression (CSD) might be the driver of therapeutic benefit. Work led by @therehugolad.bsky.social
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Reposted by Georg Keller
FMI science @fmiscience.bsky.social · 15/04/2026
In this interview, @juliabatki.bsky.social, FMI’s newest group leader, reflects on the early curiosity that drew her to science, why FMI is the right home for her lab, how studying cell clearance could help us understand disease, and her love of improv. www.fmi.ch/news-events/...
fmi.ch
Curiosity, cell clearance, and improv: A chat with Julia Batki
In this interview, Julia Batki, FMI’s newest group leader, reflects on the early curiosity that drew her to science, why FMI is the right home for her lab, how studying cell clearance could help us un...
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Georg Keller @georgkeller.bsky.social · 31/03/2026
Very excited to share new work by Leonardo Lupori. In mice, a single dose of the antipsychotic clozapine results in changes to behavior and cortical activity patterns that remain detectable a week later. www.biorxiv.org/content/10.6...
biorxiv.org
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Georg Keller @georgkeller.bsky.social · 19/03/2026
Truly beautiful work. The first good evidence that prediction error driven plasticity actually functions to reduce prediction errors!
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Reposted by Georg Keller
Dinu F Albeanu @dinanthos.bsky.social · 10/03/2026
Join us at TENSS 2026 to open black boxes, explain how things/brains work and debate the impact (or lack or it) of various new technologies on understanding of the brain and on society. tenss.ro Apply by: March 15th!
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Alex Schier @schierlab.bsky.social · 24/02/2026
Deadline March 1. Join the new Dietschy Facility for Tissue Science. www.biozentrum.unibas.ch/open-positio...
biozentrum.unibas.ch
Research Specialist in Microscopy and Spatial Transcriptomics (80-100%)
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Georg Keller @georgkeller.bsky.social · 30/01/2026
We think cortex might function like a JEPA. It looks like prediction errors in layer 2/3 are not computed against input (as is the idea in predictive processing), but against a representation in latent space (i.e. like in a JEPA arxiv.org/abs/2301.08243 or RPL doi.org/10.1101/2025...).
arxiv.org
Self-Supervised Learning from Images with a Joint-Embedding Predictive Architecture
This paper demonstrates an approach for learning highly semantic image representations without relying on hand-crafted data-augmentations. We introduce the Image-based Joint-Embedding Predictive Archi...
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Reposted by Georg Keller
allen institute @alleninstitute.org · 12/01/2026
Join leading scientists for a 3.5-day #LakeConference discussion on: "The Neurobiology of Mental Health" at the level of genes, cell types, organoids, circuits, networks and brain systems. Learn more & apply by January 31: lakeconferences.org/conf/1ed63fdb-d…
The Neurobiology of Mental Health 2026 from May 17 – May 21 in Thun, Switzerland.
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Reposted by Georg Keller
Lake Conferences @lakeconferences.bsky.social · 05/01/2026
Join us this May to explore the biological mechanisms of mental health challenges and treatment strategies. Apply by January 31: lakeconferences.org
lakeconferences.org
Home - Lake Conferences
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Reposted by Georg Keller
Friedemann Zenke @fzenke.bsky.social · 27/11/2025
1/6 New preprint 🚀 How does the cortex learn to represent things and how they move without reconstructing sensory stimuli? We developed a circuit-centric recurrent predictive learning (RPL) model based on JEPAs. 🔗 doi.org/10.1101/2025... Led by @atenagm.bsky.social @mshalvagal.bsky.social
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Georg Keller @georgkeller.bsky.social · 26/11/2025
One of the most promising approaches to making headway in understanding the cortical algorithm that I have seen in a long time! www.biorxiv.org/content/10.1...
biorxiv.org
Understanding cortical computation through the lens of joint-embedding predictive architectures
Tracking prey or recognizing a lurking predator is as crucial for survival as anticipating their actions. To guide behavior, the brain must extract information about object identities and their dynami...
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Reposted by Georg Keller
FMI science @fmiscience.bsky.social · 20/11/2025
In this first-person account, FMI’s senior communications manager describes taking part in an early human trial that adapts previous experiments in mice to explore how the human brain responds when visual and auditory information suddenly fall out of sync. www.fmi.ch/news-events/...
fmi.ch
Inside the tunnel: Experiencing the brain’s response to sensory mismatches
In this first-person account, FMI’s senior communications manager describes taking part in an early human trial that adapts previous experiments in mice to explore how the human brain responds when vi...
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Reposted by Georg Keller
allen institute @alleninstitute.org · 03/11/2025
Applications are open for the #LakeConference on the Neurobiology of Mental Health in Lake Thun, Switzerland. 📆 May 17-21, 2026 🏔️ All career stages welcome ⏳ Apply by January 31, 2026 Learn more and apply: t.co/WcuXHdWnFa @lakeconferences.bsky.social
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Reposted by Georg Keller
Philipp Sterzer @psterzer.bsky.social · 22/10/2025
Very much looking forward to this collaboration with @georgkeller.bsky.social at @fmiscience.bsky.social, using a cross-species approach in humans and mice to investigate the effects of antipsychotics on cortical circuit function.
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Reposted by Georg Keller
Lake Conferences @lakeconferences.bsky.social · 13/10/2025
Join us for the second Neurobiology of Mental Health conference (May 2026) that will explore the biological mechanisms underlying mental health challenges and their treatment. Information and application on: lakeconferences.org. The deadline for applications is January 31st, 2026.
lakeconferences.org
Home - Lake Conferences
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Reposted by Georg Keller
Philipp Sterzer @psterzer.bsky.social · 13/10/2025
Please share: Postdoc position available in a new collaborative SNSF project with @georgkeller.bsky.social at @fmiscience.bsky.social using a cross-species approach in humans and mice to investigate the cortical circuit mechanisms underlying schizophrenia. Apply at karriere.upk.ch/Postdoctoral...
karriere.upk.ch
Stellenangebot Postdoctoral Researcher (PostDoc m/f) 100% Translational Psychiatry Lab for 2 Years bei Universitäre Psychiatrische Kliniken Basel UPK
Forschung in Klinik für Erwachsene (UPKE)
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Reposted by Georg Keller
Kris Jensen @kristorpjensen.bsky.social · 24/09/2025
I’m super excited to finally put my recent work with @behrenstimb.bsky.social on bioRxiv, where we develop a new mechanistic theory of how PFC structures adaptive behaviour using attractor dynamics in space and time! www.biorxiv.org/content/10.1...
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Reposted by Georg Keller
FMI science @fmiscience.bsky.social · 17/09/2025
This year's Ruth Chiquet Prize goes to @solygamagda.bsky.social, who sent a video message, for her work on how the brain detects sensory mismatches. Read more at: www.fmi.ch/news-events/...
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Reposted by Georg Keller
FMI science @fmiscience.bsky.social · 08/09/2025
🚨 We're hiring, please share! The FMI seeks a tenure-track Group Leader (Assistant Prof) in Structural Biology 🔬 Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...
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Georg Keller @georgkeller.bsky.social · 19/08/2025
I often get asked “do you think visuomotor mismatch responses are a mouse thing?” – it looks like at least humans have them as well. very excited by this!
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Reposted by Georg Keller
eLife @elife.bsky.social · 21/07/2025
Ditching months-long delays for fast, constructive feedback. This interview with @solygamagda.bsky.social dives into the experience of publishing with eLife and what it could mean for a more open and efficient future in science.
buff.ly
Publishing with eLife: “the future of science lies in greater transparency”
Neuroscientist Magdalena Solyga shares her latest study and her experience publishing with eLife.
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Reposted by Georg Keller
Dan Goodman @neural-reckoning.org · 16/07/2025
Defending science in public we often talk about 'peer reviewed science'. But could this framing contribute to undermining trust in science and holding us back from improving the scientific process? Instead, let's talk about the work that has received the most thorough and transparent scrutiny? 🧪
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Reposted by Georg Keller
eLife @elife.bsky.social · 17/06/2025
We’re pushing for a system that’s fairer for researchers, helping them get recognition for what, not where they publish. Learn about our model that eliminates accept/reject decisions. buff.ly/SCqcG4x
Illustration featuring green dots and dashes, with the heading: "Join us in the future of publishing. Be a part of our new publishing system".
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Reposted by Georg Keller
The Transmitter @thetransmitter.bsky.social · 15/04/2025
In his new book, published today, Nachum Ulanovsky calls on the field to embrace naturalistic conditions and move away from overcontrolled experiments. #neuroskyence www.thetransmitter.org/systems-neur...
thetransmitter.org
‘Natural Neuroscience,’ an excerpt
In his new book, Nachum Ulanovsky calls on the field to embrace naturalistic conditions and move away from overcontrolled experiments.
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Jérôme Lecoq @jeromelecoq.bsky.social · 15/04/2025
How does our brain predict the future? Our review of predictive processing + research program is now on arXiv arxiv.org/abs/2504.09614 50+ neuroscientists distributed across the world worked together to create this unique community project.
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Reposted by Georg Keller
Rochefort Lab @rochefortlab.bsky.social · 17/03/2025
I just received the price, thank you so much for all your work @womeninneurouk.bsky.social !!!
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Georg Keller @georgkeller.bsky.social · 13/03/2025
Consistent with the work of @jeremiahycohen.bsky.social and @mishaahrens.bsky.social labs, we find that serotonin axons in mouse visual cortex appear to signal recent visuomotor uncertainty (and unlike norepinephrine axons, they have no visuomotor mismatch responses) www.biorxiv.org/content/10.1...
biorxiv.org
Activity in serotonergic axons in visuomotor areas of cortex is modulated by the recent history of visuomotor coupling
Visuomotor experience is necessary for the development of normal function of visual cortex (Attinger et al., 2017) and likely establishes a balance between movement-related predictions and sensory sig...
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Georg Keller @georgkeller.bsky.social · 26/02/2025
Just in case you - as we did - were wondering whether humans would have any of these pesky visuomotor mismatch responses certain people have seen in mice...
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Reposted by Georg Keller
allen institute @alleninstitute.org · 25/02/2025
Applications are open for the @lakeconferences.bsky.social on Neural Coding & Dynamics in Seattle – co-hosted with Circuit Neuroscience Basel! 📆 9/28 to 10/2 📍 Seattle, USA 🧠📈 All career stages welcomed. Apply to attend by May 23: alleninstitute.org/events/lake-... #LakeConference
alleninstitute.org
Lake Conference - Neural Coding & Dynamics 2025
Join the Allen Institute and Circuit Neuroscience Basel for the Lake Conference in Seattle, Washington this September! This small conference will...
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Georg Keller @georgkeller.bsky.social · 10/02/2025
In @elife.bsky.social: Multimodal mismatch responses in mouse auditory cortex doi.org/10.7554/eLif...
doi.org
Multimodal mismatch responses in mouse auditory cortex
Audiomotor mismatch responses in auditory cortex are amplified by concurrent visuomotor mismatches, highlighting non-hierarchical and multimodal processing of prediction errors.
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Lake Conferences @lakeconferences.bsky.social · 24/01/2025
The application deadline for the Sensation and Action conference 2025 is fast approaching! Join us for an exciting set of talks and for a chance to share your ideas: www.lakeconferences.org
lakeconferences.org
Home - Lake Conferences
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Reposted by Georg Keller
eLife @elife.bsky.social · 16/01/2025
🎉 eLife is pleased to announce Timothy Behrens (@behrenstimb.bsky.social) as our new Editor-in-Chief! A distinguished neuroscientist and long-time supporter, Tim will lead our efforts in transforming research communication for all.
buff.ly
eLife appoints Timothy Behrens as Editor-in-Chief
Behrens will lead eLife’s efforts to improve research communication for all.
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FMI science @fmiscience.bsky.social · 16/12/2024
📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...
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Tim Behrens @behrenstimb.bsky.social · 30/11/2024
Although we don’t want this fight now, if we have to have it we will. We have all the funders/unis/institutes on our side. Elife papers will be treated just the same as before. And maybe we can collectively put a dent in Clarivate’s business model.
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Lake Conferences @lakeconferences.bsky.social · 22/11/2024
Join us for the Sensation and Action conference 2025 – application is now open: lakeconferences.org
lakeconferences.org
Home - Lake Conferences
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Reposted by Georg Keller
Tim Behrens @behrenstimb.bsky.social · 20/11/2024
Early days, but it looks like our authors don't think we need an impact factor either! Submissions are strong in numbers and high quality since the Clarivate/WoS announcement. We should not let a multibillion dollar company dictate how science is evaluated!
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Lake Conferences @lakeconferences.bsky.social · 07/01/2024
Join us for the Neurobiology of Mental Health conference that will explore circuit-based approaches to mental health challenges. Information and application on: lakeconferences.org. The deadline for applications is January 15th, 2024.
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