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Andreas Schaefer

@andreas-t-schaefer.bsky.social
381 followers 338 following 31 posts

Neuroscientist @crick.ac.uk asking how information is processed in the brain. Odours. Circuits. Neurotechnology. Synchrotrons. BCIs. Co-founder Paradromics Twitter: @AndreasTSchafer

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Reposted by Andreas Schaefer
Tobias Ackels @tobiasackels.bsky.social · 12/05/2026
🚨 Preprint alert! 🚨 How does the olfactory bulb transform overlapping sensory inputs into representations that are easier to distinguish? New study by Sina Tootoonian, Yikai Yang, @andreas-t-schaefer.bsky.social @crick.ac.uk and myself.‬ www.biorxiv.org/content/10.6... A short 🧵 below
biorxiv.org
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Reposted by Andreas Schaefer
Datta Lab @dattalab.bsky.social · 29/04/2026
Excited to see our paper describing a stereotyped receptor map for smell (led by @davidhbrann.bsky.social ) out in the world! See below for short thread with open access link to paper www.nytimes.com/2026/04/29/s...
nytimes.com
Scientists Unveil ‘Long Lost’ Map for Smell
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Reposted by Andreas Schaefer
Datta Lab @dattalab.bsky.social · 29/04/2026
Many thanks and congrats to all who participated in this work esp. our collaborators (Tatsuya Tsukahara, @neuroboz.bsky.social , @andreas-t-schaefer.bsky.social , and Alex Fleishmann)!
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Reposted by Andreas Schaefer
The Francis Crick Institute @crick.ac.uk · 23/03/2026
“I think it’s a real mistake to forget where the pipeline for all this begins.” John Diffley reflects on the importance of basic research, his mission to decode DNA replication and recreate it in the lab, and the scientific optimism of the 1960s that helped shape it. www.crick.ac.uk/news/2026-03...
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Reposted by Andreas Schaefer
Carles Bosch @carlesbosch.bsky.social · 24/03/2026
This work is the product of an outstanding multidisciplinary team operating across multiple countries. Special congrats to Safe Khan, lead author of the study. And congrats to all authors and supporting institutions! doi.org/10.1107/S160... @safekhan.bsky.social @andreas-t-schaefer.bsky.social
doi.org
Critical point drying of brain tissue for X-ray phase-contrast imaging
X-ray phase contrast tomography can efficiently image brain tissue at subcellular resolution. Critical point drying allows a gentle replacement of interstitial material by air, enhancing X-ray phase c...
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Reposted by Andreas Schaefer
Carles Bosch @carlesbosch.bsky.social · 24/03/2026
#paper: Drying tissue samples enhances contrast in X-ray phase contrast imaging while largely preserving ultrastructure. 🧠🔬 doi.org/10.1107/S160... @safekhan.bsky.social @andreas-t-schaefer.bsky.social @crick.ac.uk @embl.org @imperialcollegeldn.bsky.social @esrf.fr @uclnpp.bsky.social
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Reposted by Andreas Schaefer
The Francis Crick Institute @crick.ac.uk · 18/03/2026
“We’re hoping doors will open for researchers to ask questions about how connections are made in the brain in mice and maybe, one day, humans.” - @andreas-t-schaefer.bsky.social Read about the new NIH-funded program to map brain circuitry using X-rays: www.crick.ac.uk/news/2026-03...
crick.ac.uk
Can X-rays reveal how the brain is wired?
Neuroscientist Andreas Schaefer is spearheading a new project to capture the intricacies of the mouse brain using X-rays, bringing researchers closer to a complete map of its neural connections.
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Reposted by Andreas Schaefer
The Francis Crick Institute @crick.ac.uk · 18/03/2026
The project will be co-led by @andreas-t-schaefer.bsky.social at the Crick and Chris Jacobsen at Northwestern University, working with @esrf.fr . It is part of the NIH’s BRAIN CONNECTS programme to map neural connections in humans and animals.
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Andreas Schaefer @andreas-t-schaefer.bsky.social · 12/03/2026
Very excited to host today's #MedicineAtTheCrick event @crick.ac.uk - Interfacing the brain: from Neurons to Networks. Amazing line-up and looking forward to great talks and discussions. #BCI Angelique Paulk Kai Miller David Brandman Harith Akram Mariska Vansteensel
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Reposted by Andreas Schaefer
albaneimbert.bsky.social @albaneimbert.bsky.social · 23/02/2026
Job alert! Join the Making Lab at the @crick.ac.uk. As a senior engineer in system design, programming, and hardware–software integration, you'll develop systems that make unique experiments possible. More about the role and apply here: crick.wd3.myworkdayjobs.com/External/job...
crick.wd3.myworkdayjobs.com
Senior/Principal Laboratory Research Scientist
Salary for this Role: SLRS: From £45,700 per annum with benefits, subject to skills and experience PLRS: From £55,555 per annum with benefits, subject to skills and experience Job Title: Senior/Princi...
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Reposted by Andreas Schaefer
albaneimbert.bsky.social @albaneimbert.bsky.social · 14/11/2025
Job alert! Join the Making Lab at the @crick.ac.uk. As a senior engineer in system design, programming, and hardware–software integration, you'll develop systems that make unique experiments possible. More about the role and apply here: crick.wd3.myworkdayjobs.com/External/job...
crick.wd3.myworkdayjobs.com
Principal Laboratory Research Scientist
Salary for this Role: From £55,555 per annum with benefits, subject to skills and experience Job Title: Principal Laboratory Research Scientist Reports to: Albane Imbert Closing Date: 27/Nov/2025 23.5...
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Reposted by Andreas Schaefer
Casey Schneider-Mizell @csdashm.com · 20/02/2026
From @bdpedigo.bsky.social: a super efficient, highly reliable, and very generalizable method for mesh structure classification, applied here to spine detection across basically every synapse onto a cell in the MICRoNS dataset.
Mesh analysis pipeline showing feature extraction and spine classification.
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Reposted by Andreas Schaefer
The Francis Crick Institute @crick.ac.uk · 26/01/2026
Book your free tickets now for our next #MedicineAtTheCrick event on Thursday 12 March, hosted by @andreas-t-schaefer.bsky.social, where researchers and clinicians will explore ‘neurotechnologies’ that help us better understand and decode the brain. www.eventbrite.co.uk/e/medicine-a...
eventbrite.co.uk
Medicine at the Crick| Interfacing the human brain: neurons to networks
Hybrid event taking place virtually and in person, organised by The Francis Crick Institute, London
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Andreas Schaefer @andreas-t-schaefer.bsky.social · 17/01/2026
www.nature.com/naturecareer...
nature.com
Department Chair, Duke Neurobiology - Duke University, Durham job with Duke University - School of Medicine | 12852576
The Duke University School of Medicine (SOM) seeks a distinguished neuroscientist to serve as the next Chair of the Department of Neurobiology.
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Reposted by Andreas Schaefer
FocalPlane @focalplane.bsky.social · 14/01/2026
🔬🔦Our latest ‘Imaging spotlight’, by @carlesbosch.bsky.social, Ana Diaz, @adrianawanner.bsky.social & @andreas-t-schaefer.bsky.social, highlights the non-destructive X-ray tomography pipeline that the authors developed to map mouse brain ultrastructure & considers future applications & developments.
focalplane.biologists.com
Imaging spotlight: Revealing mouse brain ultrastructure using non-destructive X-ray tomography - FocalPlane
Imaging spotlight: Revealing mouse brain ultrastructure using non-destructive X-ray tomography - News
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Reposted by Andreas Schaefer
Carles Bosch @carlesbosch.bsky.social · 14/01/2026
Here's a spotlight article on our recent study! Tissue ultrastructure can be resolved with X-rays, which impacts not only how we can study neuronal circuits but soft tissues more generally. Kudos to Ana Diaz, @adrianawanner.bsky.social, @andreas-t-schaefer.bsky.social and all authors.
focalplane.biologists.com
Imaging spotlight: Revealing mouse brain ultrastructure using non-destructive X-ray tomography - FocalPlane
Imaging spotlight: Revealing mouse brain ultrastructure using non-destructive X-ray tomography - News
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Reposted by Andreas Schaefer
Nature Methods @natmethods.nature.com · 04/12/2025
An optimized X-ray nanotomography method offers an attractive alternative to volume EM for connectomics. @crick.ac.uk @psich.bsky.social psich.bsky.social @adrianawanner.bsky.social @andreas-t-schaefer.bsky.social @ucl.ac.uk @uclnpp.bsky.social www.nature.com/articles/s41...
nature.com
Nondestructive X-ray tomography of brain tissue ultrastructure - Nature Methods
Optimizations of X-ray nanotomography including the choice of resin allows high-resolution imaging of mouse brain tissue, approaching the resolution of volume electron microscopy. Since it does not re...
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Reposted by Andreas Schaefer
Adrian Wanner @adrianawanner.bsky.social · 27/11/2025
By repurposing a radiation-hard epoxy resin from the nuclear/aerospace industry, we made samples withstand >1.15×10¹⁰ Gy and reached sub-40 nm resolution, revealing axons, dendrites, mitochondria and synapses without sectioning.
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Reposted by Andreas Schaefer
Adrian Wanner @adrianawanner.bsky.social · 27/11/2025
In a fantastic collaboration co-led by Ana Diaz (@psich.bsky.social), Carles Bosch @carlesbosch.bsky.social) and Andreas Schaefer (@andreas-t-schaefer.bsky.social) from @crick.ac.uk,we tackled a key barrier in X-ray ultrastructural imaging: achieving <40 nm resolution without destroying tissue.
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Andreas Schaefer @andreas-t-schaefer.bsky.social · 27/11/2025
X-rays can resolve ultrastructure - milestone for ultrastructure imaging w/o cutting. Thanks to an amazing team - @carlesbosch.bsky.social @adrianawanner.bsky.social Ana Diaz and collaborators @crick.ac.uk @psich.bsky.social and @esrf.fr and funders @wellcometrust.bsky.social @ukri.org
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Andreas Schaefer @andreas-t-schaefer.bsky.social · 14/11/2025
Enthusiastic about connectomics and X-rays? Several positions in our group at Crick for postdocs and senior scientists (permanent!). DM me if interested – and let’s talk if you are at Sfn next days or at the NIH BRAIN CONNECTS meeting today! Please share!
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Andreas Schaefer @andreas-t-schaefer.bsky.social · 14/11/2025
Join us at Crick - amazing team and great colleagues to collaborate on exciting design and development projects
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Andreas Schaefer @andreas-t-schaefer.bsky.social · 09/11/2025
Bit more than 2 weeks to go... DM me if you will be in San Diego at SfN and want to talk about it. Please share.
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Andreas Schaefer @andreas-t-schaefer.bsky.social · 02/11/2025
Very excited to continue our amazing collaboration with @apacureanu.bsky.social at @esrf.fr - thank you @wellcometrust.bsky.social and all the collaborators at @crick.ac.uk and @esrf.fr
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Andreas Schaefer @andreas-t-schaefer.bsky.social · 09/10/2025
The Crick is an absolutely amazing place to work in - please share this opportunity widely with your colleagues and postdocs - and DM me if I can help in any way
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Andreas Schaefer @andreas-t-schaefer.bsky.social · 07/10/2025
Judging by the last ones, this will be amazing - and with all the new developments at next gen synchrotrons, even more timely. Please re-post, join in person if you can travel to London or via zoom
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Reposted by Andreas Schaefer
The Francis Crick Institute @crick.ac.uk · 02/10/2025
Motivated graduates with backgrounds in biological or biomedical sciences, physics, chemistry, mathematics, engineering and/or computer science are invited to apply to our 4-year fully funded PhD programme. Apply by 05 November 2025 www.crick.ac.uk/careers-and-...
crick.ac.uk
PhD students
Our PhD programme attracts the brightest scientific minds and is an opportunity for talented people to embark on their career in biomedical research.
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Reposted by Andreas Schaefer
Sven Truckenbrodt @sventruckenbrodt.bsky.social · 22/09/2025
The Molecular Brain Mapping group at the MRC-LMB is hiring! 🌈🧠 I'm looking for people who are excited about developing multimodal analysis and visualization tools to capture the "hidden connectome," in a highly intersectional environment exploring ideas in meta-science. mrc.tal.net/vx/mobile-0/...
mrc.tal.net
Imaging Data Engineer - Neurobiology - Dr Sven Truckenbrodt - LMB 2697 - Medical Research Council
Location: Cambridge. Vacancy: Imaging Data Engineer - Neurobiology - Dr Sven Truckenbrodt - LMB 2697. Closing Date: 09/10/2025, 23:55
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Andreas Schaefer @andreas-t-schaefer.bsky.social · 01/10/2025
Lots of exciting clinical PhD projects at Crick - including the opportunity for neurosurgeons to work with us and record electrical activity in patients with neuropixels probes. Please share widely!
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Andreas Schaefer @andreas-t-schaefer.bsky.social · 25/09/2025
Great opportunity to work with an amazing team on the frontiers of X-ray connectomics www.psi.ch/en/hr/job-op...
psi.ch
Postdoctoral Fellow on high-throughput X-ray laminography
The Paul Scherrer Institute PSI is the largest research institute for natural and engineering sciences within Switzerland. We perform cutting-edge research in the fields of future technologies, energy...
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Reposted by Andreas Schaefer
Sainsbury Wellcome Centre @sainsburywellcome.bsky.social · 23/09/2025
Applications are now open for the SWC Systems Neuroscience PhD Programme. Join us in London! 🧠 World-class neuroscience training 💰 Fully-funded 4-year programme 🖥️ Close links to @gatsbyucl.bsky.social Apply by 3 Nov: www.sainsburywellcome.org/web/content/...
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Carles Bosch @carlesbosch.bsky.social · 10/09/2025
#preprint: We optimised the preparation of tissues for #X-ray phase contrast imaging. Drying tissue samples (instead of embedding them) brings more signal in #X-ray phase contrast images. The process largely preserves #ultrastructure. @safekhan.bsky.social @andreas-t-schaefer.bsky.social
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Safe Khan @safekhan.bsky.social · 10/09/2025
Our pre-print is out! Critical point drying of brain tissue for x-ray phase contrast imaging. @apeart.bsky.social @yuxinzhang.bsky.social @jkbrmn.bsky.social @apacureanu.bsky.social @andreas-t-schaefer.bsky.social @carlesbosch.bsky.social @esrf.fr @crick.ac.uk bioarXiv: doi.org/10.1101/2025...
doi.org
Critical point drying of brain tissue for X-ray phase contrast imaging
X-ray phase contrast tomography is emerging as a powerful method for imaging large volumes of brain tissue at sub-cellular resolution. However, current sample preparation methods are largely inherited...
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Reposted by Andreas Schaefer
Gaspar Jekely @jekely.biologists.social.ap.brid.gy · 01/09/2025
We are looking for an IT engineer with a focus on operations and research data management at the Centre for Organismal Studies at @uniheidelberg in Heidelberg, Germany #IT #sysadmin #linux #ResearchData please help to spread this opening […] [Original post on biologists.social]
Heidelberg castle by night with reflections of light in the Neckar river
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Venki Murthy @neurovenki.bsky.social · 01/09/2025
We watched mice follow scent trails drawn on an “endless” treadmill. By manipulating trail geometry/statistics, perturbing mouse nose & brain, and modeling behavior with a Bayesian framework, we show that mice use predictive (rather than reactive) strategies.
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Thomas Nowotny @drtnowotny.bsky.social · 05/07/2025
And we are off - excited that #cns2025florence is under way with record attendance - first keynote starts in 5 minutes.
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Tim Behrens @behrenstimb.bsky.social · 05/07/2025
Scary. Authors building in hidden instructions for presumed LLM peer reviewers (in white text on white background).
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Katharina Schmack @kathaschmack.bsky.social · 06/07/2025
Clinical research in England is wild! 3+ years, 20+ meetings, 200+ documents, 500+ emails is what it can take to open a fully funded, observational non-CTIMP study. Thank you @chrischirp.bsky.social and colleagues for calling attention to this urgent, solvable crisis! www.bmj.com/content/390/...
bmj.com
Health research in England is grinding to a halt
Wes Streeting, the UK health and social care secretary, announced in 2024 that “the NHS is broken” against a background of ballooning waiting lists, delays in disease detection, and reduced staff prod...
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DurstewitzLab @durstewitzlab.bsky.social · 06/07/2025
We wrote a little #NeuroAI piece about in-context learning & neural dynamics vs. continual learning & plasticity, both mechanisms to flexibly adapt to changing environments: arxiv.org/abs/2507.02103 We relate this to non-stationary rule learning tasks with rapid performance jumps. Feedback welcome!
arxiv.org
What Neuroscience Can Teach AI About Learning in Continuously Changing Environments
Modern AI models, such as large language models, are usually trained once on a huge corpus of data, potentially fine-tuned for a specific task, and then deployed with fixed parameters. Their training ...
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Frank Norman @franknorman.bsky.social · 06/07/2025
Great thread, showing how even the most educated people need humility to accept what they dont’t know. That’s the way you will learn.
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Janelia Research Campus @hhmijanelia.bsky.social · 06/07/2025
🏊 Serotonin controls how hard a zebrafish swims as changes in its body or environment effect its effort. Now, researchers are uncovering how neurons figure out when & how much serotonin to secrete – providing new insights into neuromodulation ➡️ www.janelia.org/news/new-res...
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Katrin Vogt @katrinvogt.bsky.social · 06/07/2025
Tomorrow the second Behavioral Neurobiology Summer School in Collaboration with the Pristina International Summer University will start at University of Pristina, Kosovo!! Thank you Ilir Mazreku for having us over for a visit from Konstanz! Thank you Flutura Shabani for all the organization!
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UCL Faculty of Brain Sciences @uclbrainscience.bsky.social · 05/07/2025
🧵 It's #ResearchAppreciationDay! 🔬 🧪 🧬 Time to shout out our brilliant UCL researchers changing lives daily! Here are just a few of our top research stories of 2025:
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Tim Vogels @tpvogels.bsky.social · 30/06/2025
Here is your last reminder that the application deadline for Imbizo.Africa is nearing quickly, the 1st of July, in fact tomorrow. Still the place where diversity is at its best in the world! Tell all who need to hear. #africa #neuro
imbizo.africa
#Imbizo - Simons Computational Neuroscience Imbizo - #Imbizo
Simons Computational Neuroscience Imbizo summer school in Cape Town, South Africa
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Reposted by Andreas Schaefer
The Francis Crick Institute @crick.ac.uk · 25/06/2025
Crick researchers have shown that the ‘pacemaker’ controlling yeast cell division is located inside the nucleus, rather than outside it as was previously thought. This research was led by @nitinkapadia.bsky.social and Paul Nurse. www.crick.ac.uk/news/2025-06...
crick.ac.uk
Researchers show that the cell nucleus is the pacemaker for cell division
Researchers at the Francis Crick Institute have shown that the 'pacemaker' controlling yeast cell division lies inside the nucleus rather than outside it, as previously thought. Having the pacemaker i...
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The Francis Crick Institute @crick.ac.uk · 25/06/2025
Researchers at the Crick and UCL have developed laboratory models of dementia, including Alzheimer's, to show that certain genetic messages are misplaced in diseased nerve cells. The finding could offer a potential target for new treatments for neurodegeneration. www.crick.ac.uk/news/2025-06...
crick.ac.uk
Researchers identify lost genetic messages as a target for treating dementia
Researchers at the Francis Crick Institute and UCL have shown that genetic messages are misplaced in nerve cells in a model of Alzheimer’s disease and frontotemporal dementia.
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HHMI @hhmi-science.bsky.social · 25/06/2025
ATTN: students & postdocs in #theoreticalneuroscience! Applications are now open for @hhmijanelia.bsky.social's "by the students, for the students" #neurotheory workshop, which will take place Nov. 9 - 14, 2025.
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eLife @elife.bsky.social · 25/06/2025
Your nose remembers scents, literally! A new mouse study finds that repeated exposure to certain smells triggers the growth of more neurons tuned to those odours. Over time, this could help fine-tune your sense of smell 👃
buff.ly
Sniffing out new neurons
A mouse study sheds light on how repeated exposure to specific odors can shape the population of neurons that detect them.
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Andreas Schaefer @andreas-t-schaefer.bsky.social · 25/06/2025
10th London Impact Neurotechnology Meeting & King's Surgical Grand Round 📅 June 26th 1730 📍London Institute for Healthcare Engineering 🎟️ Register: lnkd.in/e2ZqU8Pt 🔹 Chair: Mr Jonathan Shapey 🔹Dr Jacques Carolan @jacquescarolan.bsky.social Precision Neurotechnologies 🔹Prof Gail Rosseau, MD
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