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Jane Hawkey

@yekwah.bsky.social
368 followers 167 following 30 posts

Microbial genomics - bacterial evolution, AMR, mobile elements, phylogenetics. Located at Monash University/Alfred Hospital

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Reposted by Jane Hawkey
Charlene Rodrigues @cmcrodrigues.bsky.social · 22/07/2026
Delighted to share our paper-17 years of meningococcal genomic surveillance, looking at changes in diversity, distribution and demographics in Scotland. The positive impact of vaccines and what is now circulating following COVID-19/restrictions period url.uk.m.mimecastprotect.com/s/lJN8CM1Gzc...
url.uk.m.mimecastprotect.com
Genomic epidemiology of invasive meningococcal disease in Scotland before, during, and after the COVID-19 pandemic: a retrospective observational study
Invasive meningococcal disease (IMD) remains a major global health threat. Despite vaccination, meningococcal genetic diversity means disease, includi…
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Jane Hawkey @yekwah.bsky.social · 16/07/2026
I kept waiting for this to be revealed as a piece of fiction. It was not (try reader mode to read in full)
newyorker.com
When A.I. Is a Member of the Family
A single mom, her two daughters, and the chatbots that fill in the gaps.
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Reposted by Jane Hawkey
François-Xavier WEILL @fxweill.bsky.social · 03/07/2026
Can bacterial genomics bring 70 years of epidemiological surveillance back to life? We're hiring a postdoc (2–3 years) to explore the historical evolution of Salmonella Typhi using a unique genomic dataset. More details: euraxess.ec.europa.eu/jobs/449895
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Martin Hunt @martibartfast.bsky.social · 26/06/2026
Like Artemis/ACT but wish it was easier to install and more modern? Try Seqhiker. 🧬 Native desktop app (no Java) for Windows/mac/linux 🖱️ Drag-n-drop FASTA/GenBank/GFF3/BAM/VCF files 🔍 Genome browsing and ACT-style comparison ✨ Themes (customisable) and a Vim mode Docs: seqhiker.readthedocs.io
seqhiker.readthedocs.io
The Seqhiker's Guide
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Andrew Roger @andrewjroger.bsky.social · 06/05/2026
IQ-TREE 3: Phylogenomic Inference Software using Complex Evolutionary Models academic.oup.com/mbe/article/...
academic.oup.com
IQ-TREE 3: Phylogenomic Inference Software using Complex Evolutionary Models
Abstract. IQ-TREE (https://iqtree.github.io/) is a widely used open-source software tool for efficiently inferring phylogenetic trees under maximum likelih
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Reposted by Jane Hawkey
Charles Wei @rositea.bsky.social · 06/05/2026
It took years after my masters to publish BaGPipe, now it's out! It's a Nextflow pipeline to run end-to-end bacterial GWAS, heavily tested and benchmarked on different datasets, and now in good hands of the Sanger's Pathogen Informatics Team. link.springer.com/article/10.1...
link.springer.com
BaGPipe: an automated, reproducible, and flexible pipeline for bacterial genome-wide association studies - BMC Microbiology
BMC Microbiology - Microbial genome-wide association studies (GWAS) are crucial for linking genetic variation to phenotypic traits in bacteria. However, current tools often involve complex manual...
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The Shigella Meeting @shigellameeting.bsky.social · 22/04/2026
Looking good on Day 3 of #Shigella2026 ☀️🇫🇷🧫
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Jane Hawkey @yekwah.bsky.social · 03/04/2026
@hughcottingham.bsky.social did a fantastic job on this benchmarking work, especially with the constant shifting of ONT tech!
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Dr Monique Ryan @mon4kooyong.bsky.social · 12/03/2026
Join my campaign to properly fund medical research in Australia 🔬 www.moniqueryan.com.au/medical_rese...
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Dr Andrew Lonsdale @lonsbio.bsky.social · 10/03/2026
Some background to this, and an example I think of Phil's attitudes towards fostering students and encouraging others. I never got a chance to meet Phil in person, but will share his act of generosity that helped myself and @hdashnow.bsky.social and I think had in indelible mark on our careers. 1/8
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Zamin Iqbal @zaminiqbal.bsky.social · 26/02/2026
Courtesy of @martibartfast.bsky.social , we have a new release of AllTheBacteria which adds another 322,920 assemblies, covering all ENA (illumina, isolate) prokaryotes to May 2025. allthebacteria.readthedocs.io/en/latest/ov...
allthebacteria.readthedocs.io
Overview — AllTheBacteria documentation
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Gerry Tonkin-Hill @gerrythill.bsky.social · 20/02/2026
It's a bit last minute, but we have an RA/junior postdoc position available in my lab (closing Sunday). Please reach out if you're interested in developing and applying methods to analyse microbial genomes and metagenomes! careers.petermac.org/job/MELBOURN...
careers.petermac.org
Research Assistant - Tonkin-Hill Lab
Research Assistant - Tonkin-Hill Lab
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Benoit Marteyn @marteynlab.bsky.social · 12/02/2026
To make sure the whole Shigella community will be gathered at this inaugural meeting, we have re-opened abstract submission for poster presentation until the end of the month. Please RT! www.shigella2026.conferences-pasteur.org/registration...
shigella2026.conferences-pasteur.org
Registration - EMBO Workshop Shigella: from biology to prevention
EMBO Workshop Shigella: from biology to prevention
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Jane Hawkey @yekwah.bsky.social · 12/02/2026
Spotted on the Chappell Roan merch store. I don’t think they know what Shigella is… what am I missing???
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Ben Vezina @bananabenana.bsky.social · 22/01/2026
Our new paper on Insertion Sequences (IS) in #Klebsiella - Lineages have vastly different IS loads and profiles - An inverse relationship between IS load and metabolic capacity, in particular phosphorus use, consistent with early reductive evolution. www.microbiologyresearch.org/content/jour...
microbiologyresearch.org
Exploring the IS-capades of Klebsiella pneumoniae: insertion sequences drive metabolic loss in obscure sub-lineages
Introduction. Klebsiella pneumoniae is an opportunistic pathogen that causes a wide spectrum of infections within healthcare settings and the community. Four K. pneumoniae sub-lineages, defined using ...
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Jane Hawkey @yekwah.bsky.social · 06/01/2026
Finally got my #triplej #hottest100 votes in! Thought I heard no new music this year but that was a lie, my short list was huge. Ur A Rat and Keith I can never get out of my head
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Reposted by Jane Hawkey
Ben Vezina @bananabenana.bsky.social · 17/12/2025
(1/7) Really pleased to have this published in @natcomms.nature.com We looked at all public genomes encoding blaIMP (carbapenem #AMR ) 🦠🧫🧬💊. We show 5 IMP variants achieved global endemicity while 2 are regionally endemic. www.nature.com/articles/s41... #MicroSky #microbiology #IDSky #EpiSky 🧪
nature.com
The rise and global spread of IMP carbapenemases (1996-2023): a genomic epidemiology study - Nature Communications
Carbapenemase blaIMP genes between 1996-2023 were analysed across 4,556 genomes, revealing variant-specific epidemiologies and endemicities. Horizontal gene transfer enabled broad inter-species transm...
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Ben Vezina @bananabenana.bsky.social · 13/12/2025
Absolutely stoked to have this published in @plosbiology.org We looked at the metabolism of #Klebsiella pneumoniae 🦠🧫. We not only demonstrated lineage-specific #metabolism, but that lineages can cross-feed and support each other. journals.plos.org/plosbiology/... #MicroSky #microbiology 🧬 🧪 💊
journals.plos.org
A metabolic atlas of the Klebsiella pneumoniae species complex reveals lineage-specific metabolism and capacity for intra-species co-operation
Why are there so many co-circulating Klebsiella pneumoniae clones? Using genomics and large-scale metabolic modelling of >7000 isolates, this study identifies structured, clone-specific metabolic spec...
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ace-gtdb.bsky.social @ace-gtdb.bsky.social · 11/12/2025
The GTDB website now has an ANI calculator based on skani that supports uploading of user genomes. Try it at gtdb.ecogenomic.org/tools/skani. Find more information about @jimshaw.bsky.social fantastic tool at www.nature.com/articles/s41....
gtdb.ecogenomic.org
GTDB - skani calculator
An interface to compute pairwise ANI of NCBI genomes using the GTDB taxonomy.
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Alison Mather @alisonmather.bsky.social · 08/12/2025
A new tool we’ve developed to identify AMR-associated SNPs in short- and long-read metagenome data….allows a greater understanding of the total resistome of a sample
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Matt Bevan @mattbevan.bsky.social · 13/11/2025
I can’t explain why but reading the news feels like this at the moment
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Jane Hawkey @yekwah.bsky.social · 06/11/2025
Very interesting to see what amendments were pushed by different parties for this bit of legislation. The One Nation amendment to remove a focus on public health issues caused by climate change (thankfully voted down) was typically 🙄
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Nature Reviews Genetics @natrevgenet.nature.com · 03/11/2025
New online! Microbial genomics for antimicrobial resistance ecology and action
nature.com
Microbial genomics for antimicrobial resistance ecology and action
Nature Reviews Genetics, Published online: 03 November 2025; doi:10.1038/s41576-025-00909-zMicrobial genomics can improve our understanding of antimicrobial resistance dynamics across ecosystems. In this Comment, Kathryn Holt emphasizes the interconnectedness of human, animal and environmental health and calls for greater integration of microbial genomic data through robust analytical frameworks to unravel the complexity of antimicrobial resistance dynamics.
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Kate Baker @ksbakes.bsky.social · 29/10/2025
Are you hungry for some Shigella news? Why not come to the 1st International Shigella meeting www.shigella2026.conferences-pasteur.org/home 20-24 April 2026 Paris
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EMBL-EBI @ebi.embl.org · 30/09/2025
There are millions of openly available microbial genomes, but searching them can be slow. Until now 🥁 Introducing LexicMap, a new alignment tool that lets scientists search these data in minutes, helping track antibiotic resistance, trace outbreaks, and more. www.ebi.ac.uk/about/news/r... 🦠
ebi.ac.uk
How to rapidly search the world’s microbial DNA
By making the world’s microbial DNA easier to explore, LexicMap helps researchers track outbreaks, study antibiotic resistance, and understand microbial diversity.
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Ryan Wick @rrwick.bsky.social · 29/09/2025
Happy to share that the paper describing Autocycler is now 100% up: doi.org/10.1093/bioi... (1/3)
doi.org
Autocycler: long-read consensus assembly for bacterial genomes
AbstractMotivation. Long-read sequencing enables complete bacterial genome assemblies, but individual assemblers are imperfect and often produce sequence-l
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Reposted by Jane Hawkey
Dorottya Nagy @dotnagy.bsky.social · 29/09/2025
To summarise our recent pre-print: Autocycler, the automated consensus assembler, when used with Nanopore long-read only Enterobacterales assemblies, produces more complete chromosomes and plasmids, with an accuracy comparable to hybrid assemblies.
Figure 2 from my recently pre-printed manuscript on the completeness and accuracy of Nanopore long-read only bacterial genome assembly for Enterobacterales. a) tile plot of chromosome circularisation, with assembler on the x-axis and sample on the y-axis, shows that the consensus long-read only assembler, Autocycler, circularised more chromosomes at 95% (87/92) than any other long-read or hybrid assembler. b) complex upset plot of plasmid reconstruction, showing that the best plasmid reconstruction was achieved by long-read assemblers incorporating the separate plasmid assembly tool, Plassembler, namely Autocycler and Hybracter, reconstructing >96% of plasmids.
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Christina Faherty @christinafaher1.bsky.social · 27/09/2025
A great opportunity to attend the #Shigella meeting April 20-24, 2026! Abstract submissions are open! @shigellameeting.bsky.social #Microsky
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Kate Baker @ksbakes.bsky.social · 17/09/2025
Come and join us at @shigellameeting.bsky.social in Paris 2026. Registrations are now open! www.shigella2026.conferences-pasteur.org/home and follow the Shigella starter pack go.bsky.app/6Vbwhjc (message to be added)! 215 days to go!
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Thomas Lin Pedersen @thomasp85.com · 11/09/2025
I am beyond excited to announce that ggplot2 4.0.0 has just landed on CRAN. It's not every day we have a new major #ggplot2 release but it is a fitting 18 year birthday present for the package. Get an overview of the release in this blog post and be on the lookout for more in-depth posts #rstats
tidyverse.org
ggplot2 4.0.0
A new major version of ggplot2 has been released on CRAN. Find out what is new here.
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Alexander Luckmann @aluckmann.bsky.social · 20/08/2025
Academia may not give you job security, flexibility, or wealth, but it will let you unexpectedly connect to eduroam in foreign cities
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Jane Hawkey @yekwah.bsky.social · 12/08/2025
Really liked the explanation about human understanding, and what we miss when we use black box models. This has always been my gripe with prediction models for eg AMR - I want to know why that feature is associated with resistance!
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ESCMID @escmid.bsky.social · 07/08/2025
Register today for the 14th International Meeting on Microbial Epidemiological Markers (IMMEM XIV)! Topics range from how genomics inform resistance profiling to pathogen surveillance in a #OneHealth framework. 🧬 ✍️ Register: ow.ly/gjOZ50WpOXX 👀 Programme: ow.ly/Whj850WpOXY #IDSky
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Nature @nature.com · 31/07/2025
This surprisingly relaxing footage is from SIX MILES under the ocean – and it’s the deepest ecosystem yet discovered
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Jane Hawkey @yekwah.bsky.social · 30/07/2025
Huge amount of work in this paper, very proud of Hugh getting through all these benchmarking tests. We’re much more confident now using ONT-only data for our clinical questions
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Ben Vezina @bananabenana.bsky.social · 29/07/2025
New preprint where we analysed IS loads in 🦠 #Klebsiella pneumoniae lineages and found they're inversely associated with nutrient usage. We propose an insertional tolerance model, whereby IS can only insert into metabolically-tolerable sites. #IDSky #MicroSky 🧪 www.biorxiv.org/content/10.1...
Graph showing IS loads by Klebsiella sub-lineage
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Rob Edwards @linsalrob.bsky.social · 22/07/2025
Fold first, ask later: structure-informed function annotation of Pseudomonas phage proteins Structural predictions to improve #phage genome annotation! @hannelorelongin.bsky.social @gbouras13.bsky.social y.social @susiegriggo.bsky.social @veravannoort.bsky.social www.biorxiv.org/content/10.1...
biorxiv.org
Fold first, ask later: structure-informed function annotation of Pseudomonas phage proteins
Phages, the viruses of bacteria, harbor an incredibly diverse repertoire of proteins capable of manipulating their bacterial hosts, inspiring many medical and biotechnological applications. However, t...
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MicroSeq2026 @microseqasm.bsky.social · 21/07/2025
🚨Abstract submission & registration for #MicroSeq2025 is OPEN! 🚨Get in quick! The first 50 registrations are FREE for PhD students and ECRs who are current ASM members, thanks to @aussocmic.bsky.social. Head to our website to register now 👇 www.microseqconference.com/registration...
Registration and abstract submission for MicroSeq2025 is open. Abstract submission closes August 8, 2025. Participants can register at microseqconference.com. MicroSeq2025 is an online meeting being held on September 3rd and 4th, focused on research being conducted on sequencing data generated from microbiological samples (bacteria, fungi, and viruses). MicroSeq2025 is supported by The Australian Society for Microbiology, the Australasian Virology Society, and Microbial Genomics.
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bioRxiv Bioinfo @biorxiv-bioinfo.bsky.social · 17/07/2025
A periodic table of bacteria?: Mapping bacterial diversity in trait space www.biorxiv.org/content/10.1101/202…
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Rob Edwards @linsalrob.bsky.social · 17/07/2025
The 10th anniversary #ABACBS conference will be held in Adelaide from Nov 24-28. If you're thinking of coming, get in quick, as it's going to be a big week: A fantastic #bioinformatics conference with outstanding national and international speakers, and we're wrapping up the ABACBS week an AC/DC gig
The view of the Adelaide Oval, site of the 2025 Australian Biology and Computational Biology Society (ABACBS) conference, from across the River Torrens. The conference will be held in Adelaide from 24 to 28 November and celebrates 10 years of ABACBS.
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Jane Hawkey @yekwah.bsky.social · 14/07/2025
Doesn’t destroy the planet if you use solar energy to power it - in summer our house regularly produces way more solar than we can use, our AC runs entirely off solar during the day with energy to spare
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MicroSeq2026 @microseqasm.bsky.social · 03/07/2025
🦋Hello BlueSky!🦋 Let's get right into it. MicroSeq is back September 3-4, 2025! Stay tuned for more details on registration and abstract submission coming soon here and at www.microseqconference.com. 🌟Save the date!🌟 #MicroSeq2025
A call to save the date for MicroSeq2025, returning September 3-4. MicroSeq is an online meeting where microbiology meets sequencing, including bacteria, viruses, and fungi.
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ESCMID_ESGMAP @esgmap.bsky.social · 11/07/2025
🚨Plasmid ALERT – new @eurosurveillance.org rapid comms! @ecdc.europa.eu-led study finds mosaic IncHI1B(pNDM-MAR) plasmid with blaOXA-48 + aerobactin in 492 K. pneumoniae isolates across 8 EU countries (2019–2024). First ESGMAP-backed paper: tinyurl.com/4acezh92 #AMR #plasmids #OneHealth #ESGMAP
tinyurl.com
Cross-border spread of a mosaic resistance (OXA-48) and virulence (aerobactin) plasmid in Klebsiella pneumoniae: a European Antimicrobial Resistance Genes Surveillance Network investigation, Europe, F...
An investigation of the European Antimicrobial Resistance Genes Surveillance Network (EURGen-Net) detected the same mosaic IncHI1B(pNDM-MAR) resistance (OXA-48) and virulence (aerobactin) plasmid in 4...
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Ian M. Mackay, PhD (he/him) 🦠🤧🧬📑🦟🧀 @mackayim.bsky.social · 11/07/2025
Israel: silencing dissent everywhere theshot.net.au/uncategorize...
theshot.net.au
Israel: silencing dissent everywhere - The Shot
The pro-Israel lobby isn’t designed to balance debate nor to enrich it – it is designed to silence it.
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Jerónimo Rodríguez-Beltrán @jerorb.bsky.social · 02/07/2025
🚨🚨New paper out in @natcomms.nature.com!! Come for the first large-scale analysis of plasmid copy number across species, stay for one of the most intriguing results of my lab: universal scaling laws in plasmid biology! 📈🧬 👉 www.nature.com/articles/s41...
nature.com
Universal rules govern plasmid copy number - Nature Communications
Plasmids exhibit a broad range of sizes and copies per cell, and these two parameters appear to be negatively correlated. Here, Ramiro-Martínez et al. analyse the copy number of thousands of diverse b...
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Kelly Wyres @kelwyres.bsky.social · 02/07/2025
So excited that this is now online. It's been a huge collaborative effort to estimate the prevalence of capsule and O antigens associated with #klebsiella neonatal sepsis in Africa and South Asia. The first step to prioritising antigens for a vaccine to protect 1000s of newborns. #MicroSky #AMR
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Jose F. Delgado-Blas @josefdelgadoblas.bsky.social · 23/06/2025
Excited to share this preprint focused on the genomic taxonomy of C. diphtheriae #diphtheria ➡️ www.biorxiv.org/content/10.1... Hope it helps advance research and surveillance of this relevant bacterial pathogen. Thanks to @sylvainbrisse.bsky.social and BEBP and BIGSdb teams for making it possible!
biorxiv.org
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Rusty Foster @rusty.todayintabs.com · 29/05/2025
Main character energy is OUT, this summer we’re bringing NPC energy. We’re posted up at the bar dropping lore and suggesting side quests. We’re leaning casually near a locked door and saying “I don’t think you have the key for that” when someone tries the handle. We’re staring at a tree.
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