Background Ruminant gut microbial communities influence host health, productivity, and methane emissions, yet viral communities across life stages remain uncharacterized. Whilst bacteriophages shape m...

The T7 bacteriophage deactivates bacterial defence systems through T7K phosphorylation of nearly all host and phage proteins during infection.

Phoebe Bridgers' new album joins a long list of artists inspired by the 70-year-old Adelaide mystery – even after it was apparently solved.

🫧🧬 From fragmented assemblies to high-quality bacteriophage genomes - Vini2/phables

Welcome to the -viz suite of tools: classic bioinformatics tools, reimagined for the browser. agviz · bamviz · genbankviz · phispyviz Each of our tools is a classic bioinformatics tool, but reimagi…

Free automated phage genome annotation -- pharokka, phold and phynteny in one pipeline.

Free automated phage genome annotation -- pharokka, phold and phynteny in one pipeline.

a short-read polishing tool for long-read assemblies - rrwick/Polypolish

a blog for miscellaneous bioinformatics stuff

The Great Barrier Reef Microbial Genomes Database compiles prokaryotic, viral and eukaryotic genomes from seawater collected from the Great Barrier Reef, providing a rich resource for the study of mar...

The rapid rate of virus discovery renders manual curation by taxonomy experts increasingly impractical, creating a need for reliable software that can reproducibly assign viral contigs to taxa at all ...

How a casual conversation and a satchel-dependent courier service for honey bees led to a reasearch project that employed three PhD students – so far.

The gut microbiome of the honey bee is relatively simple, but its phages are not well studied. Here, Basler et al. use metagenomics to provide a comprehensive catalogue of honey bee gut phag...

High mutation rates erode viral sequence similarity, obscuring deep evolutionary history. While protein structure is far more conserved than sequence, its use in evolutionary studies has historically ...

Whole-genome sequencing (WGS) is central to foodborne pathogen surveillance and cross-border outbreak detection. Long-read sequencing using Oxford Nanopore Technologies (ONT) promises rapid, complete,...

a blog for miscellaneous bioinformatics stuff

All kingdoms of life have developed strategies to limit viral infection. In humans, interferons induce a suite of antiviral factors that collectively provide immunity. Some human immune genes are homo...

Quantifying short-term evolutionary rates of microbial genomes is essential for understanding the processes that shape within-host evolution and for establishing thresholds needed to track transmissio...

The evolutionary emergence of complex multicellularity in bacteria and fungi, such as the ability for mycelial growth, is strongly associated with increased genomic carriage of biosynthetic machinery ...

a blog for miscellaneous bioinformatics stuff

A standalone Streamlit app that collects community priority weights over fourassembly-QC metrics ...

a blog for miscellaneous bioinformatics stuff

Folddisco enables protein structural motif search in million scale databases.

Folddisco enables protein structural motif search in million scale databases.

A single bacteriophage can dominate microbial communities yet only evolves when migration changes its ecological context.

Australian researcher, George Bouras, has recently contributed an extraordinary 17 million protein predictions to the AlphaFold Protein Structure Database. This work was possible thanks to the availability of the ColabFold tool on Setonix AMD, the result of collaboration between BioCommons and the P

AbstractMotivation. Assembly graphs are a fundamental data structure used by genome and metagenome assemblers to represent sequences and their overlap info