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Jose F. Delgado-Blas

@josefdelgadoblas.bsky.social
127 followers 190 following 10 posts

Postdoc researcher at Institut Pasteur | Bacterial genomics | Evolution, ecology and diversity of bacterial populations

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Reposted by Jose F. Delgado-Blas
Institut Pasteur | 130 years of biomedical research @pasteur.fr · 23/07/2026
Institut Pasteur researchers describe LIN codes in PLOS Biology: a standardized numerical system for identifying bacterial strains from genome data, now used in BIGSdb-Pasteur and Pathogenwatch for outbreak surveillance. @sylvainbrisse.bsky.social ↘️ doi.org/10.1371/journal.pbio.3003781
doi.org
Life Identification Numbers: A strain nomenclature approach to aid epidemiological surveillance of bacterial pathogens
Unified bacterial strain taxonomies are needed for coherent communication of findings in microbiological research. This Essay provides an overview of a novel bacterial strain taxonomy and describes ho...
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Reposted by Jose F. Delgado-Blas
François-Xavier WEILL @fxweill.bsky.social · 03/07/2026
Can bacterial genomics bring 70 years of epidemiological surveillance back to life? We're hiring a postdoc (2–3 years) to explore the historical evolution of Salmonella Typhi using a unique genomic dataset. More details: euraxess.ec.europa.eu/jobs/449895
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Reposted by Jose F. Delgado-Blas
sylvain Brisse @sylvainbrisse.bsky.social · 04/06/2026
It's out! The LIN code approach for genomic taxonomy of microbial strains and its applications in genomic epidemiology journals.plos.org/plosbiology/...
journals.plos.org
Life Identification Numbers: A strain nomenclature approach to aid epidemiological surveillance of bacterial pathogens
Unified bacterial strain taxonomies are needed for coherent communication of findings in microbiological research. This Essay provides an overview of a novel bacterial strain taxonomy and describes ho...
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Reposted by Jose F. Delgado-Blas
Professor Lesley Hoyles @bugsinyourguts.bsky.social · 08/05/2026
The 1st Klebsiella Epidemiology and Biology Symposium in 2024 was much needed and a great event, so I'm really looking forward to the 2nd in 2027.
2nd KLEBS meeting will be convened in Cape Town, South Africa in 2027!
When? November 17-19, 2027
Where? Century City Conference Centre, Cape Town, South Africa
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Reposted by Jose F. Delgado-Blas
Keith Jolley @kjolley.bsky.social · 02/03/2026
BIGSdb v1.52.1 has been released. This adds 2 new plugins for LIN code visualisation - LINtree (@giphy-ip.bsky.social) and LINvis. See github.com/kjolley/BIGS... for release notes. BIGSdb powers all the databases at @pubmlst.org and BIGSdb Pasteur.
Tree drawn within the iTOL interface generated by LINtree. The tree is annotated with LIN codes and clonal complexes in different colours.LINvis displays datasets of LIN codes as a series of hierarchical packed circles.
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Reposted by Jose F. Delgado-Blas
nstoesser.bsky.social @nstoesser.bsky.social · 24/02/2026
Are you a post-doctoral microbiologist interested in characterising bacterial resistance evolution and want to apply your knowledge and expertise to developing new therapeutics for Klebsiella (and other Enterobacterales) infections? Then we need you! Apply now bit.ly/3MX39Ce close date March 13th 👀
my.corehr.com
Job Details
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Reposted by Jose F. Delgado-Blas
sylvain Brisse @sylvainbrisse.bsky.social · 17/02/2026
A novel version of diphtOscan is available at gitlab.pasteur.fr/BEBP/diphtos.... v2.2.0 makes it easy to install on local computers. diphtOscan scans genomes and extracts information including #diphtheria toxin and antimicrobial resistance genes, biovar, species and subtyping information.
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Reposted by Jose F. Delgado-Blas
Chiara Crestani @chcrestani.bsky.social · 28/01/2026
🧫 Our publication,“Global perspectives on Klebsiella epidemiology and biology: conference report on the KLEBS 2024 symposium,” is now out! 📄 Link to paper: www.nature.com/articles/s44... @kelwyres.bsky.social @katholt.bsky.social @sylvainbrisse.bsky.social @pasteur.fr
nature.com
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Reposted by Jose F. Delgado-Blas
Chiara Crestani @chcrestani.bsky.social · 27/01/2026
🚨 Last few days to register for our Nanopore Users Day 2026! Registration is free but mandatory, as places are limited, don’t miss out! Join us for a day of scientific exchanges and networking focused on ONT sequencing and its applications! @chloebaum.bsky.social @pasteur.fr @nanoporetech.com
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Reposted by Jose F. Delgado-Blas
sylvain Brisse @sylvainbrisse.bsky.social · 14/01/2026
Dear #AMR #genomics and big data community: please be informed that the programme of the Wellcome AMR conference in Hinxton on March 23-26th is now online: coursesandconferences.wellcomeconnectingscience.org/event/antimi... - please register before Feb 24th for onsite participation
coursesandconferences.wellcomeconnectingscience.org
Antimicrobial Resistance – Genomes, Big Data and Emerging Technologies — 20260323
Highlighting the importance of genomic data in the fight against AMR
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Reposted by Jose F. Delgado-Blas
Manuel Ares-Arroyo @aresarroyom.bsky.social · 14/01/2026
Bacteria chromosomes contain Genomic Islands that provide virulence, antibiotic resistance, MGE-defence,... They transfer between cells, but the mechanism of most remains elusive. Here we explore the conjugative capacity of these mysterious Genomic Islands. www.biorxiv.org/content/10.6...
biorxiv.org
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Jose F. Delgado-Blas @josefdelgadoblas.bsky.social · 16/12/2025
What drives the K. pneumoniae species complex (KpSC) to thrive from hospitals to soils? In this study, we investigate how pangenome structure and functional diversity shape KpSC adaptability across phylogenetic and ecological contexts. (Thread) www.biorxiv.org/content/10.6...
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Reposted by Jose F. Delgado-Blas
Ben Vezina @bananabenana.bsky.social · 13/12/2025
Absolutely stoked to have this published in @plosbiology.org We looked at the metabolism of #Klebsiella pneumoniae 🦠🧫. We not only demonstrated lineage-specific #metabolism, but that lineages can cross-feed and support each other. journals.plos.org/plosbiology/... #MicroSky #microbiology 🧬 🧪 💊
journals.plos.org
A metabolic atlas of the Klebsiella pneumoniae species complex reveals lineage-specific metabolism and capacity for intra-species co-operation
Why are there so many co-circulating Klebsiella pneumoniae clones? Using genomics and large-scale metabolic modelling of >7000 isolates, this study identifies structured, clone-specific metabolic spec...
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Reposted by Jose F. Delgado-Blas
sylvain Brisse @sylvainbrisse.bsky.social · 30/11/2025
Huge preprint if you are interested in bacterial strain taxonomy! The why and how of cgMLST LIN codes: An extensively revised and expanded version doi.org/10.1101/2024... I will summarize it for you in this thread 👇
doi.org
Life Identification Numbers: A bacterial strain nomenclature approach
Unified strain taxonomies are needed for the epidemiological surveillance of bacterial pathogens and international communication in microbiological research. Core genome multilocus sequence typing (cg...
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Jose F. Delgado-Blas @josefdelgadoblas.bsky.social · 26/11/2025
Great work on the power of the cumulative cgMLST approach for the genotypic discrimination of Klebsiella pneumoniae phylogenetic groups! Happy to have participated in this fascinating study led by @armovse.bsky.social and @sylvainbrisse.bsky.social.
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Reposted by Jose F. Delgado-Blas
Kat Holt @katholt.bsky.social · 18/11/2025
The @klebnet.bsky.social team are pleased to share slides from our “Klebsiella pneumoniae Genomic Epidemiology & Antimicrobial Resistance” lecture series! Topics include Kleb diversity, lineages, AMR, hypervirulence, how to use Kaptive & Kleborate for typing, and more! klebnet.org/2025/11/18/k...
klebnet.org
Klebsiella pneumoniae genomics tutorials – KlebNET-GSP
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Reposted by Jose F. Delgado-Blas
sylvain Brisse @sylvainbrisse.bsky.social · 16/11/2025
It’s out ! Evolution of Bordetella parapertussis, the second agent of whooping cough: many parallelisms with Bordetella pertussis, including rapid adaptation by loss of the pertactin vaccine antigen. Just published in @microbiosoc MGen journal www.microbiologyresearch.org/content/jour...
microbiologyresearch.org
No innocent bystanders: pertussis vaccination and evolutionary parallelisms between Bordetella parapertussis and Bordetella pertussis
Pathogens adapting to the human host and to vaccination-induced immunity may follow parallel evolutionary paths. Bordetella parapertussis (Bpp) contributes significantly to the burden of whooping coug...
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Reposted by Jose F. Delgado-Blas
Chiara Crestani @chcrestani.bsky.social · 07/11/2025
📢 Save the Date! The 2nd Nanopore Users Day will take place 🗓️10 March 2026 at the Duclaux Amphitheater, Institut Pasteur (Paris). This edition will be open to external participants! 👉 More details and registration info coming soon! @chloebaum.bsky.social @pasteur.fr @nanoporetech.com
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Reposted by Jose F. Delgado-Blas
Oliver Schwengers @oschwengers.bsky.social · 06/10/2025
Dear community, Bakta needs your help! To further improve the functional annotation of "hypothetical" CDS, me and @gbouras13.bsky.social, we are looking for the worst Bakta-annotated bacterial genomes ;-) (1/2)
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Jose F. Delgado-Blas @josefdelgadoblas.bsky.social · 21/09/2025
It's time to go home after #IMMEMXIV. It's been 4 days of great sessions, people, and food. Thanks to the organizers and participants. I hope to see so many colleagues and friends again soon.
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Reposted by Jose F. Delgado-Blas
ESCMID @escmid.bsky.social · 07/08/2025
Register today for the 14th International Meeting on Microbial Epidemiological Markers (IMMEM XIV)! Topics range from how genomics inform resistance profiling to pathogen surveillance in a #OneHealth framework. 🧬 ✍️ Register: ow.ly/gjOZ50WpOXX 👀 Programme: ow.ly/Whj850WpOXY #IDSky
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Carlos Serna @cserna.bsky.social · 17/07/2025
Our paper “Global dissemination of npmA mediated pan‑aminoglycoside resistance via a mobile element in Gram‑positive bacteria” is now in @natcomms.nature.com. Part of my freshly defended PhD, so doubly happy! 😄🎉 🧵 (1/14) www.doi.org/10.1038/s414...
doi.org
Global dissemination of npmA mediated pan-aminoglycoside resistance via a mobile genetic element in Gram-positive bacteria - Nature Communications
The authors investigate the distribution of the aminoglycoside resistance gene npmA in Gram-positive bacteria via a mobile genetic element, highlighting its global presence and cross-species transfer ...
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Jose F. Delgado-Blas @josefdelgadoblas.bsky.social · 17/07/2025
Supercool work on a new variant of the pan-aminoglycoside resistance gene npmA, led by @cserna.bsky.social and @bgzorn.bsky.social. Really happy to have participated in it with so many friends and collaborators! Go check it out: www.nature.com/articles/s41...
nature.com
Global dissemination of npmA mediated pan-aminoglycoside resistance via a mobile genetic element in Gram-positive bacteria - Nature Communications
The authors investigate the distribution of the aminoglycoside resistance gene npmA in Gram-positive bacteria via a mobile genetic element, highlighting its global presence and cross-species transfer ...
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Jose F. Delgado-Blas @josefdelgadoblas.bsky.social · 23/06/2025
Excited to share this preprint focused on the genomic taxonomy of C. diphtheriae #diphtheria ➡️ www.biorxiv.org/content/10.1... Hope it helps advance research and surveillance of this relevant bacterial pathogen. Thanks to @sylvainbrisse.bsky.social and BEBP and BIGSdb teams for making it possible!
biorxiv.org
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Reposted by Jose F. Delgado-Blas
sylvain Brisse @sylvainbrisse.bsky.social · 12/06/2025
The BIGSdb-Pasteur project, running under my supervision since 20 years, is looking for a project manager - great opportunity to contribute to this high-profile international resource in the field of reference strain taxonomies, genomic epidemiology and antimicrobial resistance surveillance
research.pasteur.fr
Project manager: Genomic taxonomy of bacterial strains, epidemiological surveillance and antimicrobial resistance - Research
We are looking for a project manager to develop our activities around the genomic taxonomy of bacterial strains and the corresponding platform at https://bigsdb.pasteur.fr/. The project manager’s main...
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Reposted by Jose F. Delgado-Blas
NEJM.org @nejm.org · 04/06/2025
A new report describes the genetic epidemiology and antimicrobial-resistance patterns of a surge of cases of 𝘊𝘰𝘳𝘺𝘯𝘦𝘣𝘢𝘤𝘵𝘦𝘳𝘪𝘶𝘮 𝘥𝘪𝘱𝘩𝘵𝘩𝘦𝘳𝘪𝘢𝘦 infection that was identified in migrant populations in Europe. Read the full report: nej.md/3HEF3ZS #MedSky #IDSky
nej.md
Corynebacterium diphtheriae Outbreak in Migrant Populations in Europe | NEJM
A surge of cases of Corynebacterium diphtheriae infection was observed in reception centers for migrants in Europe beginning in the summer of 2022. Most of the cases were cutaneous, although some r...
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Reposted by Jose F. Delgado-Blas
Chiara Crestani @chcrestani.bsky.social · 26/05/2025
Thrilled to share our new @natcomms.nature.com paper “Microevolution and genomic epidemiology of the diphtheria-causing zoonotic pathogen Corynebacterium ulcerans” with @sylvainbrisse.bsky.social! Read more ▶️ www.nature.com/articles/s41... @pasteur.fr #GenomicEpidemiology #Zoonoses #OneHealth
nature.com
Microevolution and genomic epidemiology of the diphtheria-causing zoonotic pathogen Corynebacterium ulcerans - Nature Communications
This study reveals prior undetected transmission events of Corynebacterium ulcerans, suggesting pets play an intermediary role between wildlife and humans. Two main sublineages were identified, showin...
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KlebNET-GSP @klebnet.bsky.social · 21/05/2025
We are pleased to launch the KlebNET Genomic Epidemiology Consortium! We aim to build a public metadata repository; systematic risk framework for global genomic surveillance; and genomic epi reviews for high-impact #Klebsiella clones. Join us here: klebnet.org/klebnet-gsp-... #ABPHM25
klebnet.org
KlebNET-GSP
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Reposted by Jose F. Delgado-Blas
Marit Hetland @genomarit.bsky.social · 22/05/2025
Happy to share this resource of 568 closed Klebsiella pneumoniae species complex hybrid assemblies, including 1416 plasmids! ⭕️🦠 We hope this will be useful - short reads, long reads, hybrid assembly or all combined - for your own tools/validations 🥳 #Microsky journals.asm.org/doi/10.1128/...
journals.asm.org
Complete genomes of 568 diverse Klebsiella pneumoniae species complex isolates from humans, animals, and marine sources in Norway from 2001 to 2020 | Microbiology Resource Announcements
Klebsiella pneumoniae species complex are opportunistic pathogens that can transmit between humans, animals, and the environment (1). Here, we report hybrid genome assemblies of 578 (568 complete) gen...
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