Sign in

Nikolay Kukushkin

@niko-kukushkin.bsky.social
628 followers 1.3K following 125 posts

Neuroscientist, author, teacher. Time patterns in cellular memory ⌛️ Prof NYU Liberal Studies/Neural Science. Book upcoming 2025 (Prometheus US / Swift Press UK). Agent: JP Marshall. linktr.ee/nikolaykukushkin

PostsRepliesMedia
Nikolay Kukushkin @niko-kukushkin.bsky.social · 18/01/2026
Removing dopamine from the brain doesn't simply paralyse it. Instead, it puts it in the dark room – a state of nonaction and nonexperience in which it does not feel compelled to do anything at all. Full excerpt from "One Hand Clapping" on BBC Future www.bbc.com/future/artic...
130
Reposted by Nikolay Kukushkin
It’s just Rick @treesand.bsky.social · 19/11/2025
A wonderful trip through the history of life on earth. Thank you for an entertaining and informative book. I'm not done yet, no spoilers. Don't tell me how it ends.
021
Reposted by Nikolay Kukushkin
Neuroscience and Beyond @neuroandbeyond.bsky.social · 29/11/2025
How neurons make the brain special 🎥 Watch Episode #29 with Prof. Nikolay Kukushkin @niko-kukushkin.bsky.social to explore how #Neurons and other body cells store #Memory. Watch the full episode on this link: youtu.be/x4dvE3uawyw?...
011
Nikolay Kukushkin @niko-kukushkin.bsky.social · 26/11/2025
It’s incredible that I can now do this. Googling decent graphics for class is over. The prompt is visualizing the predictive coding architecture of the cerebral cortex.
071
Nikolay Kukushkin @niko-kukushkin.bsky.social · 16/11/2025
Hello #SfN25, come see our poster about cellular memory and multiple kinds of pattern detection operating in kidney cells. Poster LBP077 1-5pm 🧠🫘
061
Nikolay Kukushkin @niko-kukushkin.bsky.social · 14/11/2025
“One Hand Clapping reclaims the story of life from a cold, indifferent universe and brings it back into the warmth of the fire circle, where stories make sense of mysteries and offer guidance for how to live.” Thank you @sadieding.bsky.social and @wsj.com for this amazing review!
061
Nikolay Kukushkin @niko-kukushkin.bsky.social · 13/11/2025
Thank you Harvard Science Talks for a warm welcome!
041
Nikolay Kukushkin @niko-kukushkin.bsky.social · 10/11/2025
Boston! Join us this Wednesday at 6pm at the Harvard Science Center for my book talk! Get your free ticket here: www.eventbrite.com/e/nikolay-ku...
060
Nikolay Kukushkin @niko-kukushkin.bsky.social · 09/11/2025
Does a Roomba have agency? Explain pls.
010
Nikolay Kukushkin @niko-kukushkin.bsky.social · 08/11/2025
One Hand Clapping is currently #1 top new release in evolutionary psychology on US Amazon! 😲🤩
040
Nikolay Kukushkin @niko-kukushkin.bsky.social · 02/11/2025
Evan and I share an appreciation for the beauty of life’s building blocks — check out this discussion of One Hand Clapping, and my work on cellular memory youtu.be/pyg6MkM8kz0
youtu.be
Meet the Neuroscientist Who Proved Every Cell in Your Body Has a Memory!
YouTube video by Giant's Shoulder
050
Nikolay Kukushkin @niko-kukushkin.bsky.social · 31/10/2025
Fantastic review of One Hand Clapping in New Scientist!
031
Nikolay Kukushkin @niko-kukushkin.bsky.social · 20/10/2025
Great discussion of my upcoming book, One Hand Clapping, on the BBC Instant Genius pod. How do you get from nature’s ideas, to sea slug’s ideas, to human ideas? Where do you draw the line? And what will the next thing be? Get a good sense of the book in 30 min. podscan.fm/podcasts/ins...
020
Nikolay Kukushkin @niko-kukushkin.bsky.social · 18/10/2025
One Hand Clapping is out Oct 21 in North America and Oct 28 everywhere else. Preorder now! www.amazon.com/gp/aw/d/1493...
030
Nikolay Kukushkin @niko-kukushkin.bsky.social · 17/10/2025
Nothing feels as sci fi as shipping genes on a piece of paper. This DNA came from Australia, got lost in Singapore but made it to NYC. We’ll put these genes that someone designed halfway around the world into a drop of water and then into our cells, and they will express them. How insane is that.
020
Nikolay Kukushkin @niko-kukushkin.bsky.social · 17/10/2025
I’m sorry but what is contextual reasoning and normative criteria if not statistical priors and lexical associations?
110
Nikolay Kukushkin @niko-kukushkin.bsky.social · 16/10/2025
Super interesting. Seen these beautiful flowers in the Adirondacks. So, are they just parasites on fungi? Seems so hard to imagine the hosts can’t knock them off with some enzyme if all they do is leech nutrients. Is there still something in it for the fungus? Do the flowers also disperse spores? 🤔
010
Nikolay Kukushkin @niko-kukushkin.bsky.social · 16/10/2025
The big q is what exactly do you get with neuron+astro plasticity that you can’t get with neurons alone. My bet is that astros act like spatial buffers of plasticity. They retain less specific information than neurons but integrate the average state of the neighborhood and broadcast it locally.
020
Reposted by Nikolay Kukushkin
The Transmitter @thetransmitter.bsky.social · 08/10/2025
In this episode, @braininspired.bsky.social talks with @niko-kukushkin.bsky.social about his new book, ‘One Hand Clapping: Unraveling the Mystery of the Human Mind.’ #neuroskyence www.thetransmitter.org/brain-inspir...
thetransmitter.org
Nikolay Kukushkin discusses his book, ‘One Hand Clapping: Unraveling the Mystery of the Human Mind’
He explains how meaning arises in the interactions found throughout nature and evolution, from molecules to minds.
062
Nikolay Kukushkin @niko-kukushkin.bsky.social · 07/10/2025
My book, One Hand Clapping, landed in the NYU bookstore! Preorder yours today! Out everywhere Oct 21 www.barnesandnoble.com/w/one-hand-c...
051
Nikolay Kukushkin @niko-kukushkin.bsky.social · 06/10/2025
Describing this as a “break” on the immune system is the wrong metaphor. It implies that the immune system is static at rest, gets going upon infection, and then needs to be stopped, like a car. NOTHING in biology is static. Everything is an equilibrium. It’s not a break, it’s a counterweight.
020
Nikolay Kukushkin @niko-kukushkin.bsky.social · 06/10/2025
To hold something steady on an outstretched hand, you press down on your wrist with your second hand (e.g. cops holding guns in movies). That, in a nutshell, is why we need these T-regulatory cells that work against actual antiviral T-cell fighters. Congratulations!
042
Nikolay Kukushkin @niko-kukushkin.bsky.social · 01/10/2025
Ubiquitin is made in a five-pack. The last monomer has a tail. Apparently this last tailed ubiquitin is a special "fast ubiquitin" for stress. An E4 ligase (which extends already existing Ub chains and so forces them into the proteasome) grabs it under stress. Tell me AI could have predicted this
030
Nikolay Kukushkin @niko-kukushkin.bsky.social · 30/09/2025
If you are in NYC, join us for my book launch party! Tuesday October 7th 5:30pm, NYU, Liberal Studies lobby, 726 Broadway, 6th floor (non-NYU: dm me to register). Conversation between myself and Prof. Jared Simard, our resident classicist! Books available! Slavic food! events.nyu.edu/event/onehan...
events.nyu.edu
ONE HAND CLAPPING: Consciousness, Evolution, and the Meaning of Life.
Science says that you are nothing but a chemical reaction — a collection of atoms and molecules, like rocks, paperclips, and everything else in t...
031
Reposted by Nikolay Kukushkin
Claire L. Evans @theuniverse.bsky.social · 30/07/2025
What can a cell remember? A lot more than you think. My latest, for @quantamagazine.bsky.social, is on memory beyond the brain—in tiny unicellular creatures and the smallest, most ancient parts of ourselves: www.quantamagazine.org/what-can-a-c...
quantamagazine.org
What Can a Cell Remember? | Quanta Magazine
A small but enthusiastic group of neuroscientists is exhuming overlooked experiments and performing new ones to explore whether cells record past experiences — fundamentally challenging what memory is...
1105
Reposted by Nikolay Kukushkin
Neuroscience and Beyond @neuroandbeyond.bsky.social · 01/09/2025
Ever wondered where memory truly lives? 🧠 In our latest episode, we welcome Prof. Nikolay Kukushkin @niko-kukushkin.bsky.social (NYU), to discuss the biology of memory and consciousness. ▶️ Watch the full clip here: youtu.be/VY9gqT7rs_A 🔗 More: linktr.ee/neuroscience...
youtu.be
Where Is Our Memory Stored? Everywhere and Nowhere
YouTube video by Neuroscience and Beyond
021
Nikolay Kukushkin @niko-kukushkin.bsky.social · 29/04/2025
We may not sense the progress bar, but human beings are running low on memory. Here’s what we can do. www.psychologytoday.com/us/blog/smal...
psychologytoday.com
Are Humans Running Out of Memory?
Human memory has a limit. As a civilization, we may have reached it. What happens now?
021
Nikolay Kukushkin @niko-kukushkin.bsky.social · 04/02/2025
Had a great time talking about sea slugs, cellular memory, and my upcoming book with Shekerah and Fatu of We Love Science. Listen here: "Ep 66: Memory and the Human Mind - The Work" at www.buzzsprout.com/1720419/epis...
buzzsprout.com
Ep 66: Memory and the Human Mind - The Work - We Love Science
Our special guest for today is Nikolay Kukushkin, a clinical associate professor and neuroscientist at NYU, and author, who also considers himself a molecular philosopher. His research answers the que...
030
Nikolay Kukushkin @niko-kukushkin.bsky.social · 03/02/2025
Here's a biological mystery that stumps me. What's the deal with iodine in thyroid hormones? OK, it helps the hormone pass through the membrane and bind to the receptor. But steroids do that without any exotic atoms. Why iodine, and why thyroid? Any experts?
021
Nikolay Kukushkin @niko-kukushkin.bsky.social · 23/01/2025
So true. Vitamins are ridiculous.
020
Nikolay Kukushkin @niko-kukushkin.bsky.social · 17/01/2025
Time travelers would be amazed by how much we plan for future health. We take vitamins, count fiber, exercise, and do Dry January — all for benefits we won't see for years. But it might be that even shorter-term patterns leave lasting imprints on our body. 🧵
140
Nikolay Kukushkin @niko-kukushkin.bsky.social · 16/01/2025
One of the odd things about non-neural memory we study is how long it lasts — in neurons same genes get deactivated in hours, in kidney cells they stay on for days. This might be why. Neurons repress memory genes stronger. Increases information capacity? Claude Shannon again!!
040
Nikolay Kukushkin @niko-kukushkin.bsky.social · 14/01/2025
ARE YOU KIDDING
031
Nikolay Kukushkin @niko-kukushkin.bsky.social · 13/01/2025
A reminder that our NYC Russian book club meets to discuss Vladimir Sorokin’s “Day of the Oprichnik” in two weeks, Sunday 26 Jan, 3:30pm, Toné Cafe, Brighton Beach! DM to join.
010
Nikolay Kukushkin @niko-kukushkin.bsky.social · 11/01/2025
Swiss guard uniforms are actually camouflage in dichromatic vision
041
Nikolay Kukushkin @niko-kukushkin.bsky.social · 11/01/2025
What a metaphor for the unpredictability of the real world. We are trying to solve climate change and cancer and we can't even figure out what's going on with tennis balls. Real life is an infinite parameter space. defector.com/has-the-tenn...
defector.com
Has The Tennis Ball Gotten Worse? | Defector
The best way to snap an athlete out of platitude autopilot in a press conference is to get them to vent about some technical complaint. Like everyone else, they have esoteric gripes about their workpl...
071
Nikolay Kukushkin @niko-kukushkin.bsky.social · 04/01/2025
Excellent piece about our recent paper on cellular memory. And yet: quotation marks in the post, and “memory-like processes” in the article. I suspect the authors get it when I emphasize it’s not a metaphor —that’s the whole point—but then the editors just can’t let it go without conditionalizing.
094
Nikolay Kukushkin @niko-kukushkin.bsky.social · 28/12/2024
The connection between body and emotion is deep and many interpret our research on non-neural memory in that vein: kidneys store trauma, hearts carry personality. Here’s a much more realistic connection: the insula. A brain region that literally builds emotional awareness out of bodily states.
0319
Nikolay Kukushkin @niko-kukushkin.bsky.social · 25/12/2024
Honored to be on #NPR for this Christmas segment about our research on memory outside the brain. Will it help students do better on finals? I wish. Happy holidays! #neuroscience #memory #brain #christmas academicminute.org/2024/12/niko...
academicminute.org
Nikolay Kukushkin, New York University - Kidney Cells Learn Like College Students - The Academic Minute
Memories are a big part of celebrating the holidays, but is more than your brain involved in this process? Nikolay Kukushkin, clinical associate professor of life science at New York University, looks...
1160
Nikolay Kukushkin @niko-kukushkin.bsky.social · 19/12/2024
Tried using Claude as a scantron for finals today and it’s absolute garbage—reads every question and answer but can’t figure out how many mistakes there are. Reminds me of the Pirahã who can talk about each child but can’t tell you how many they have. www.science.org/doi/10.1126/...
science.org
Numerical Cognition Without Words: Evidence from Amazonia
Members of the Pirahã tribe use a “one-two-many” system of counting. I ask whether speakers of this innumerate language can appreciate larger numerosities without the benefit of words to encode them. ...
060
Nikolay Kukushkin @niko-kukushkin.bsky.social · 10/12/2024
We think of our own, biological memory the way we think of computer memory: the more, the better. But that’s not what evolution intended when it created learning. Learning is not just about storing information: it is about choosing what to store and what to discard. 🧵/1
Sea hares getting weighed
2135
Nikolay Kukushkin @niko-kukushkin.bsky.social · 08/12/2024
It’s obviously good advice for English speakers, but— does this reflect a Eurocentric left-to-right bias? I wonder what’s more intuitive for Hebrew- or Arabic-speaking scientists.
120
Nikolay Kukushkin @niko-kukushkin.bsky.social · 06/12/2024
Being a prof is great. In September I get out of things by saying “the semester just started so it’s crazy”. In October I say “oof well we’re in the thick of the semester”. In December—“well it’s the end of the semester, so, you know”. And in the summer—hell, gotta plan that semester. #highered
031
Nikolay Kukushkin @niko-kukushkin.bsky.social · 04/12/2024
This is crazy. A virus creates this zombie spiral which takes a ubiquitin ligase adaptor from the cell and uses it to label a transcription factor, needed for antiviral defence, for destruction. It’s like when the Bene Gesserit do their TAKE OUT YOUR KNIFE—DRIVE IT IN YOUR THROAT #cellbiology #dune
141
Nikolay Kukushkin @niko-kukushkin.bsky.social · 04/12/2024
This reminds me about a decade-old Soylent-era conversation with my wife about a true bachelor chow — can you make one? She would ask “but what about X?” (vitamins, fiber, flavonoids, diversity of flavor and nutrients) and I would answer “it’s in the chow!” Eventually she said I was being a tech bro
020
Nikolay Kukushkin @niko-kukushkin.bsky.social · 03/12/2024
Okay so gamma is bottom-up data, alpha is top-down prediction, beta is dopamine, delta is synaptic downscaling, and theta episodic memory. What have I oversimplified beyond reason?
230
Nikolay Kukushkin @niko-kukushkin.bsky.social · 03/12/2024
Don’t quote me on this, but this is why my personal exercise routine is to run until I smell acetone.
071
Nikolay Kukushkin @niko-kukushkin.bsky.social · 01/12/2024
A great feature about our research by @scinews.bsky.social. Had a bit of a philosophical debate with the editors: initially “memory” was in quotation marks, and the first sentence conditionalized it as “metaphorical”. But I stood my ground. There’s no sense in which “brain memory” is more “real”!
sciencenews.org
Like brain cells, kidney cells can form memories
Scientists found memory’s molecular machinery at work in cells outside the nervous system.
0225
Nikolay Kukushkin @niko-kukushkin.bsky.social · 01/12/2024
My students treat spelling like an obsolete chore. But studies show that how we learn to spell determines more than just writing, and might in fact shape our abilities, personalities, and even, quite possibly, national cultures. 🧵
open.substack.com
SPELLING / NATIONAL CULTURES
Could spelling be the reason English speakers excel in science, Italians in music, and Russians — in math?
192
Nikolay Kukushkin @niko-kukushkin.bsky.social · 28/11/2024
I’m such a city boy I’ve ever actually seen a tractor plough IRL. Nothing lays bare the raw power of machine age quite like it. In Brazil, I read about the reaction of Amazonians to seeing a metal axe cut down a tree for the first time — I imagine this, to a farmer, was similar.
020