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Maximilian Friedrich, vertigologist

@vertigologist.bsky.social
828 followers 273 following 41 posts

Neurologist and Neuroscientist studying movement and balance through the lens of computer vision, neuroimaging and neurostimulation. @University Hospital Ulm by way of @braincircuits.bsky.social

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Reposted by Maximilian Friedrich, vertigologist
Hadas Weiss @hadas.bsky.social · 24/05/2025
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Reposted by Maximilian Friedrich, vertigologist
Frederic Schaper @fredschaper.bsky.social · 24/03/2025
Is generalized epilepsy a seizure of the whole brain or a specific brain network? In our new paper out now in @naturecomms.bsky.social, we investigate this by combining brain abnormalities and DBS with the human connectome. Paper: nature.com/articles/s41... A 🧵 below:
nature.com
A generalized epilepsy network derived from brain abnormalities and deep brain stimulation - Nature Communications
Ji et al. identify an idiopathic generalised epilepsy network that links heterogeneously distributed brain abnormalities to a common brain network and deep brain stimulation sites which reduce general...
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 24/03/2025
Best of luck- we’re cheering for ya!
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Reposted by Maximilian Friedrich, vertigologist
Michael Okun @michaelokun.bsky.social · 07/03/2025
About 12,000 people globally have signed up and the United States and Canada are lagging behind. It is mostly video content and enjoyable. The course closes for feedback analysis and development at the end of March so I challenge you to jump on board. mooc.utas.edu.au/course/20278...
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 21/02/2025
Neurologists use videos to augment the clinical examination, and new AI methods promise to transform these videos into granular biomarkers. Here, we review the fascinating past, present and future of AI-powered video analyses in clinical neurology. Enjoy! jamanetwork.com/journals/jam...
jamanetwork.com
Computer Vision in Clinical Neurology and AI Augmentation of the Neurological Examination
This narrative review outlines recent advances and challenges in technologies arising from computer vision, a branch of artificial intelligence (AI), which has the potential to improve clinical neurol...
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 17/02/2025
Pretty sure I don‘t have to introduce Andy, so to make it very short: interested in DBS and brain networks? Check out this super exciting new institute in Cologne!
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Reposted by Maximilian Friedrich, vertigologist
Andrew Pines @andrewpines.bsky.social · 12/02/2025
What brain regions are involved in causing psychotic symptoms? Take a moment away from the existential dread about the future of science, and join me in this summary of some incredibly cool stuff that could help patients! 1/n🧵
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Reposted by Maximilian Friedrich, vertigologist
Andreas Horn @andreashorn.org · 12/02/2025
Do lesions that cause psychosis fall into a common brain network? Exciting new work by @andrewpines.bsky.social, @shansiddiqi.bsky.social and colleagues – tweetorial below by the first author, paper here: jamanetwork.com/journals/jam...
jamanetwork.com
Mapping Lesions That Cause Psychosis
This case-control study analyzes published cases of lesion-induced psychosisTo assess whether lesions that cause secondary psychosis have functional connections to a common brain circuit
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Reposted by Maximilian Friedrich, vertigologist
Center for Brain Circuit Therapeutics @braincircuits.bsky.social · 12/02/2025
New Center paper out at JAMA psychiatry: jamanetwork.com/journals/jam...
jamanetwork.com
Mapping Lesions That Cause Psychosis
This case-control study analyzes published cases of lesion-induced psychosisTo assess whether lesions that cause secondary psychosis have functional connections to a common brain circuit
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Reposted by Maximilian Friedrich, vertigologist
Michael Fox @foxmdphd.bsky.social · 10/01/2025
Awesome thread by @andreashorn.org on his recent paper on STN DBS for dystonia. Details a great collaboration and his thought process as the study evolved. @braincircuits.bsky.social
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 10/01/2025
Great thread and interesting work which further supports the idea that axial dystonic symptoms map closer to cerebellar networks. Nicely aligns with old (and some new) lesion and experimental midbrain stim studies
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 02/01/2025
What an impressive list of achievements! Congrats Doug!
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Reposted by Maximilian Friedrich, vertigologist
Michael Fox @foxmdphd.bsky.social · 24/12/2024
Cool to see our work from @braincircuits.bsky.social featured in @sciam.bsky.social today. Great read on an interesting and bizarre neurological condition. www.scientificamerican.com/article/how-...
scientificamerican.com
How Rare ‘Alice in Wonderland Syndrome’ Warps Reality
Researchers are learning what causes Alice in Wonderland syndrome, a rare neurological condition that can appear to warp bodies, time and reality itself
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 24/12/2024
Wonderful christmas read featuring our network mapping work on Alice in Wonderland syndrome- a bizarre and fascinating perceptual disorder. Kudos @sciam.bsky.social @foxmdphd.bsky.social @braincircuits.bsky.social www.scientificamerican.com/article/how-...
scientificamerican.com
How Rare ‘Alice in Wonderland Syndrome’ Warps Reality
Researchers are learning what causes Alice in Wonderland syndrome, a rare neurological condition that can appear to warp bodies, time and reality itself
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Reposted by Maximilian Friedrich, vertigologist
bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 22/12/2024
Spanning spatial scales with functional imaging in the human brain; initial experiences at 10.5 Tesla www.biorxiv.org/content/10.1101/202…
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 20/12/2024
I have one of these and can confirm they induce a cathartic experience. Great for grants and life!
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 15/12/2024
Great take. It‘s sometimes bewildering to me just how advanced imaging pipelines are, while at the same time, behavioral assessments are very rudimentary and crude.
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Reposted by Maximilian Friedrich, vertigologist
Emily Moin @emilymoin.com · 11/12/2024
I think a fun teaching exercise for medical students would be to each take a common clinical pearl and trace the citations until you find the primary data it's based on.
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Reposted by Maximilian Friedrich, vertigologist
Andreas Horn @andreashorn.org · 05/12/2024
Showed a glimpse of a new atlas that we're building in Paris yesterday. Pretty excited about it and implications for network modeling.
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 05/12/2024
It‘s a wrap! Do you have a video database you‘d like to analyze? Feel free to reach out, or DIY as our code is #opensource. Enjoy the read!
media.tenor.com
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 05/12/2024
This machine learning framework uncovers latent, but relevant pathosignatures of dystonia. We envision its integration into the modern canon of neuromodulation, neurotechnology and neuroimaging (did I hear dysfunctome?), powering translational & precision Neurology
media.tenor.com
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 05/12/2024
Finally, data driven analyses of head/neck movements converge on an almost identical feature set across different types of dystonia, supporting the idea that dystonia subtype and severity map onto a "kinematic continuum"
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 05/12/2024
We also find that phasic (tremulous) and tonic (fixed deviations) dystonia components may map to different circuits. Movement disorders aficionados had this gut feeling for quite a while
media.tenor.com
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 05/12/2024
We identified a set of clinically-inspired features from full video assessments that provide additional insights into disease severity, subtype & brain stim effects. We found: tremor matters! (but hasn't even been quantified in scores for a long time...)
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 05/12/2024
We develop a visual computer vision framework which extracts a rich, yet intuitively interpretable set of kinematic features of head movement dynamics- from videos taken several years (or decades) ago in 7 different academic centers!
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 05/12/2024
Paying homage to "medical cinematography", we develop a deep learning framework to evaluate dystonia severity & characterize effects of brain stimulation, using only standard clinical videos! How?!
media.tenor.com
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 05/12/2024
🧐 Dystonia is a neurological movement disorder characterized by complex, twisting and tremulous movement abnormalities. Clinical scores are simple and easy to administer, but fail to capture the true complexity of the dystonic phenotype.
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 05/12/2024
Can computer vision help us turn clinical videos into quantifiable digital biomarkers of Dystonia? Our recent paper suggests yes! Let‘s recap first. www.nature.com/articles/s41...
nature.com
Head movement dynamics in dystonia: a multi-centre retrospective study using visual perceptive deep learning - npj Digital Medicine
npj Digital Medicine - Head movement dynamics in dystonia: a multi-centre retrospective study using visual perceptive deep learning
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Reposted by Maximilian Friedrich, vertigologist
Science News @scinews.bsky.social · 03/12/2024
Hypothalamic deep brain stimulation augments walking after spinal cord injury (SCI). #NatureMedicine #medsky #scisky "Targeting specific brain regions to maximize the engagement of spinal cord-projecting neurons in the recovery of neurological functions after SCI." www.nature.com/articles/s41...
nature.com
Hypothalamic deep brain stimulation augments walking after spinal cord injury - Nature Medicine
Whole-brain anatomical and activity surveys identify the lateral hypothalamus as a key driver of recovery from spinal cord injury, leading to a deep brain stimulation therapy that augments the recover...
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Reposted by Maximilian Friedrich, vertigologist
eLife @elife.bsky.social · 01/12/2024
Combining electrophysiological, anatomical and functional brain maps reveals networks of beta neural activity that align with dopamine uptake. buff.ly/4eQnzET
buff.ly
Brain Activity: Unifying networks of a rhythm
Combining electrophysiological, anatomical and functional brain maps reveals networks of beta neural activity that align with dopamine uptake.
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 02/12/2024
@isaiahneuro.bsky.social
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 02/12/2024
📌
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Reposted by Maximilian Friedrich, vertigologist
M.J. Crockett @mjcrockett.bsky.social · 01/12/2024
Our new paper in @science.org shows that misinformation evokes more outrage than trustworthy news, and when it does it’s shared more & read less. bsky.app/profile/will...
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Reposted by Maximilian Friedrich, vertigologist
Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 18/11/2024
Have you ever felt like you're in a surreal world where sizes and scales are all warped? No, it's not a fantasy—it's a real medical condition! Come dive with me into this mind-bending phenomenon called Alice in Wonderland Syndrome (AIWS): onlinelibrary.wiley.com/doi/abs/10.1...
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 28/11/2024
Spot on. Plus, menscheln has a fairly benign connotation of „the human condition“- which is dearly needed in these heated times!
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 28/11/2024
I strongly endorse the introduction of the concept „to menscheln“ globally :-) Enjoy the run!
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Reposted by Maximilian Friedrich, vertigologist
Journal of Cognitive Neuroscience (JoCN) @jocn.bsky.social · 26/11/2024
dlvr.it
Effects of Vergence Eye Movement Planning on Size Perception and Early Visual Processing
AbstractOur perception of objects depends on non-oculomotor depth cues, such as pictorial distance cues and binocular disparity, and oculomotor depth cues, such as vergence and accommodation. Although vergence eye movements are always involved in…
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 24/11/2024
Feel free to add me, too @vertigologist.bsky.social
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Reposted by Maximilian Friedrich, vertigologist
Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 22/11/2024
Tremor is common, and measuring its dynamic characteristics is important for disgnosis and prognostication. Marker-based motion capture helps, but is very resource-intensive. What if we could analyze tremor just with a smartphone video?! 🧠 www.nature.com/articles/s41...
nature.com
Validation and application of computer vision algorithms for video-based tremor analysis - npj Digital Medicine
npj Digital Medicine - Validation and application of computer vision algorithms for video-based tremor analysis
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 22/11/2024
Tremor is common, and measuring its dynamic characteristics is important for disgnosis and prognostication. Marker-based motion capture helps, but is very resource-intensive. What if we could analyze tremor just with a smartphone video?! 🧠 www.nature.com/articles/s41...
nature.com
Validation and application of computer vision algorithms for video-based tremor analysis - npj Digital Medicine
npj Digital Medicine - Validation and application of computer vision algorithms for video-based tremor analysis
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Reposted by Maximilian Friedrich, vertigologist
Andreas Horn @andreashorn.org · 21/11/2024
Very much looking forward to this talk tomorrow by our very own @fredschaper.bsky.social together with Stanford's Robert Fisher on Epilepsy and How to get jobs in Academia! Join us on stimulatingbrains.org! @stimulatingbrains.org
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Reposted by Maximilian Friedrich, vertigologist
Altmetric @altmetric.com · 18/11/2024
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how: docs.bsky.app/docs/advance... #AcademicSky #HigherEd #Altmetrics
docs.bsky.app
Action Intent Links | Bluesky
Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...
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Reposted by Maximilian Friedrich, vertigologist
Alan Carson @alancarson15.bsky.social · 14/11/2024
www.neurology.org/doi/10.1212/... Mark Hallett’s Wartenberg lecture, dedicated to his mentor the late David Marsden
neurology.org
Functional Neurologic Disorder, La Lésion Dynamique | Neurology
Functional neurologic disorder is common and a significant cause of disability and stress in neurologic patients. The nature of this disorder has been unclear. Originally called hysteria, the disorder...
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Reposted by Maximilian Friedrich, vertigologist
Alfonso Fasano @alfonsofasano.bsky.social · 14/11/2024
One of most overlooked issues of past literature is the 'miracle' of #brain surgery in #functional patients. Cooper was a pioneer in the field but some of his success came from this, as we discussed recently in www.neurology.org/doi/10.1212/...
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Reposted by Maximilian Friedrich, vertigologist
Abhimanyu Mahajan @amahajanmd.bsky.social · 18/11/2024
PSA BlueSky allows you to curate your feed. In addition to “following”, you can choose (in your settings) to only see the feed you prefer. I deleted “discover” and replaced it with “popular with friends”. Less noise, more signal.
media.tenor.com
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 18/11/2024
I think that‘s an important feature as my experience with the feed on here has been somewhat suboptimal. I am trying to locate the feature you mentioned…
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 18/11/2024
I‘d love to be added, too Trey
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 18/11/2024
Thank you @foxmdphd.bsky.social @braincircuits.bsky.social @fredschaper.bsky.social and many others. Media coverage: @newscientist.bsky.social newscientist.com/article/2414767-alice-in-wonderland-syndrome-mapped-in-the-brain-to-improve-treatments/ and nautilus mag nautil.us/falling-down.... Enjoy!
newscientist.com
Alice in Wonderland syndrome mapped in the brain to improve treatments
Scientists have mapped the brain circuit behind a form of Alice in Wonderland syndrome, when someone sees themselves or others in distorted proportions, in research that could improve how it is treate...
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 18/11/2024
8/ As strange as they are, the distortions experienced during AIWS open a window into the fascinating neural networks that shape our perceptual experience, which is obviously very malleable. So better look twice before you believe what you see :-)
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Maximilian Friedrich, vertigologist @vertigologist.bsky.social · 18/11/2024
7/ Next, we wondered how the lesion-based AIWS network relates to heterogeneous neuroimaging findings DURING AIWS episodes. We found a truly remarkable convergence, hinting at the validity of our findings beyond lesions.
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