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Vikram Agarwal

@vagar.bsky.social
1.9K followers 383 following 82 posts

Head of mRNA Platform Design Data Science @Sanofi. R&D in mRNA therapeutics using ML/DL. Formerly @ UTAustin, MIT, MSFTResearch, UW, & Calico. Latest work: gScholar (tinyurl.com/3xdfksy6)

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Reposted by Vikram Agarwal
Jay Shendure @jshendure.bsky.social · 31/07/2026
Thrilled to post thread re: new single-cell lineage of mouse embryo reconstructed w/ DNA Typewriter. One animal, zygote to late organogenesis (E13.5). Tree has 1,340,794 transcriptionally profiled, annotated tips (cells), 1,142,588 dated internal nodes, rooted at zygote 1/n
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Vikram Agarwal @vagar.bsky.social · 18/04/2026
Haley Stevens, you got my vote!! youtu.be/MJd0rcfX-DI?...
youtu.be
Watch: Congresswoman tells RFK Jr. he "should be ashamed" and resign as HHS secretary
YouTube video by CBS News
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Reposted by Vikram Agarwal
Xuebing Wu @xuebingwu.bsky.social · 31/01/2026
Does the noncoding genome actually carry more genetic information than coding seqs? Motivated by this question we mutated every bp in the 10kb MYC locus. Results are even more exciting: Decoding the MYC locus reveals a druggable ultraconserved RNA element www.biorxiv.org/content/10.6...
biorxiv.org
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Reposted by Vikram Agarwal
Angie Rasmussen @angierasmussen.bsky.social · 14/12/2025
Take a moment to meet FDA Commissioner Marty Makary. He is the guy who is leading the agency that is working overtime to enrich his MAHA patrons by taking away your kids’ access to vaccines & essential medicines. He’s replacing evidence-based regulation with corruption.
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Reposted by Vikram Agarwal
Jeff Coller @jmcoller.bsky.social · 22/08/2025
Halting mRNA vaccine development in the US has broader implications beyond infectious diseases, impeding innovative cancer and rare disease treatments. Science is interconnected; each step forward contributes to collective knowledge and new breakthroughs. www.sciencenews.org/article/mrna...
sciencenews.org
mRNA vaccines hold promise for many diseases. Now the tech is under fire
Researchers warn that halting federal contracts for mRNA vaccine research could weaken pandemic preparedness and slow medical advances.
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Vikram Agarwal @vagar.bsky.social · 18/08/2025
One sane article in a sea of endless misinformation: www.nytimes.com/2025/08/18/o...
nytimes.com
Opinion | America Is Abandoning One of the Greatest Medical Breakthroughs
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Reposted by Vikram Agarwal
Colin Carlson @colincarlson.bsky.social · 10/08/2025
RFK Jr. should resign. Any healthy Democratic Party would demand it right now. Any public health apparatus of value would demand it right now. We are leaderless in government and academia. America is a fucking death cult
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Reposted by Vikram Agarwal
Marc Veldhoen @marcveld.bsky.social · 07/08/2025
Pseudobabble. There is deliberate confusion here. 1) The first claim is made concerning infections. Fact: No vaccine is or can be effective in stopping infections. Why? Because antibodies are our only pathogen-specific protection against infection ,and they wane. 1/4
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Reposted by Vikram Agarwal
Dr. Lucky Tran @luckytran.com · 06/08/2025
At his confirmation hearing, RFK Jr claimed he wouldn’t take away vaccines. So far he has: Removed COVID vaccine recommendations Fired the CDC’s vaccine committee Replaced scientists with antivaxxers Cancelled vaccine hesitancy research Pulled $500m in mRNA vaccine research
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The Fig Economy @figgityfigs.bsky.social · 05/08/2025
mRNA vaccines are so close to magic as to be basically indistinguishable, and the administration is stopping them because they worship death.
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Reposted by Vikram Agarwal
Boo!-per Lund @cooperlund.online · 05/08/2025
Hey congrats to everyone who took the soft anti-vaccine stance of “mRNA vaccines aren’t 100% effective and aren’t useful against future variants so the mRNA vaccines aren’t good, we need to mask forever”, your stance has been noted by RFK Jr. to kill mRNA technology in America.
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Reposted by Vikram Agarwal
Katie Mack @astrokatie.com · 05/08/2025
Every reputable expert I know considers mRNA vaccine technology to be one of the most revolutionary advances in medicine in our lifetimes. Its inventors won the Nobel Prize in 2023. Shutting it down now is pointless self-harm to humanity.
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Reposted by Vikram Agarwal
David Bartel's Lab @bartellab.bsky.social · 02/08/2025
Check out the latest study from our lab, led by Coffee Xiang (@coffeebond007.bsky.social) www.nature.com/articles/s41... (1/2)
nature.com
PAL-AI reveals genetic determinants that control poly(A)-tail length during oocyte maturation, with relevance to human fertility - Nature Communications
Gene regulation in oocytes relies heavily on poly(A) tail-length changes. Here, the authors develop PAL-AI, a neural network model that predicts tail-length changes, identifies regulatory motifs, and ...
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Reposted by Vikram Agarwal
Texas Science @texasscience.bsky.social · 25/07/2025
🧬 A new AI tool from @utaustin.bsky.social & Sanofi could speed the development of mRNA-based therapies for viruses, cancers and genetic disorders. RiboNN predicts which mRNA sequences will be most efficiently translated into proteins. cns.utexas.edu/news/researc... @taccutexas.bsky.social
cns.utexas.edu
New AI Tool Accelerates mRNA-Based Treatments for Viruses, Cancers, Genetic Disorders
UT Austin and Sanofi partner to build tool that predicts translation efficiency of mRNA sequences.
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Reposted by Vikram Agarwal
Nature Biotechnology @natbiotech.nature.com · 25/07/2025
Predicting the translation efficiency of messenger RNA in mammalian cells go.nature.com/4mgXR0C
go.nature.com
Predicting the translation efficiency of messenger RNA in mammalian cells - Nature Biotechnology
A deep convolutional neural network model predicts the influence of the full-length mRNA sequence on translation efficiency.
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Reposted by Vikram Agarwal
Nature Biotechnology @natbiotech.nature.com · 25/07/2025
Translation efficiency covariation identifies conserved coordination patterns across cell types go.nature.com/3TXvmZy
go.nature.com
Translation efficiency covariation identifies conserved coordination patterns across cell types - Nature Biotechnology
Matched ribosome profiling and RNA sequencing data quantify translation efficiency patterns across 140 human and mouse cell lines.
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Vikram Agarwal @vagar.bsky.social · 25/07/2025
Very excited that our most significant work, a collaboration w/ Dr. Can Cenik at UT Austin on translational gene regulation, was finally published in Nature Biotechnology in a dual set of studies: Paper 1 -- an AI model trained to predict translation rates from mRNA sequences: rdcu.be/exN1l
url.de.m.mimecastprotect.com
Predicting the translation efficiency of messenger RNA in mammalian cells
Nature Biotechnology - A deep convolutional neural network model predicts the influence of the full-length mRNA sequence on translation efficiency.
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Reposted by Vikram Agarwal
Elizabeth Warren @warren.senate.gov · 07/07/2025
RFK Jr.’s war on vaccines is hurting America's kids.
washingtonpost.com
U.S. measles cases reach 33-year record high as outbreaks spread
Johns Hopkins University data reflects the public health reversal in defeating the vaccine-preventable disease since measles was officially eliminated from the U.S. in 2000.
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Reposted by Vikram Agarwal
Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · 05/07/2025
Vaccine refusal, encouraged by Robert F. Kennedy Jr., has now led to the worst U.S. measles outbreak since the disease was classified as eliminated in 2000. This was preventable. Vaccines save lives and prevent hospitalizations that are physically, mentally, and financially draining.
amp.cnn.com
Measles cases surge to record high since disease was declared eliminated in the US | CNN
There have been more measles cases in the US this year than any other since the disease was declared eliminated a quarter-century ago.
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Reposted by Vikram Agarwal
Han Yuan @hy395.bsky.social · 02/06/2025
1/ DNA sequence models like Borzoi predict gene expression and variant effects across tissues — but how can someone adapt the model to a custom experiment? @drkbio.bsky.social, Johannes Linder and I propose a solution via parameter-efficient fine-tuning (PEFT). www.biorxiv.org/content/10.1...
biorxiv.org
Parameter-Efficient Fine-Tuning of a Supervised Regulatory Sequence Model
DNA sequence deep learning models accurately predict epigenetic and transcriptional profiles, enabling analysis of gene regulation and genetic variant effects. While large-scale training models like E...
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Reposted by Vikram Agarwal
Katie Mack @astrokatie.com · 03/06/2025
I've seen folks talk about how "in four years" they'll be able to get back to their planned projects and I really don't think that's going to work out. People & projects losing funding now will not be able to hit pause and come back once funding is restored. Hard-won progress & capacity will be lost
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Vikram Agarwal @vagar.bsky.social · 29/05/2025
Some exciting news! 🥳👍 finally dropped our open-source AI model to predict translation rates from mRNA sequences online for free academic use! Hope it's widely used among RNA scientists! Code: github.com/Sanofi-Publi...; Model: zenodo.org/records/1537...; Preprint: www.biorxiv.org/content/10.1...
github.com
GitHub - Sanofi-Public/RiboNN: RiboNN: predicting translation efficiencies from mRNA sequences
RiboNN: predicting translation efficiencies from mRNA sequences - Sanofi-Public/RiboNN
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Reposted by Vikram Agarwal
Dr. Lucky Tran @luckytran.com · 28/04/2025
Deaths from heart disease down 75%, that’s NIH. Deaths from stroke down 75%, that’s NIH. HIV/AIDS no longer a death sentence, that’s NIH. 99% of FDA approved drugs in the last decade, that’s NIH. Please show this video to anyone who doesn’t understand why the NIH is so important.
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Vikram Agarwal @vagar.bsky.social · 02/05/2025
At what point in history did science become partisan? Didn't we all agree that innovations help all of us? If our brother/mother/father or YOU are stricken with cancer, do you really think you have "owned the libs" by destroying NIH/NSF funding? The amount of self-inflicted destruction is dizzying 😢
nytimes.com
Trump’s Budget Calls for Deep Cuts to NIH and CDC
A budget blueprint released on Friday advances, in hard numbers and biting words, President Trump’s assault on the nation’s universities and scientific research enterprise.
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Reposted by Vikram Agarwal
Colin Carlson @colincarlson.bsky.social · 02/05/2025
I talked to Nature about the latest development at NSF, which is a five-alarm fire for American science. The scale of immediate impact is massive. We narrowly escaped this affecting @viralemergence.org for now, but will have to shut down in a few months if this stays. www.nature.com/articles/d41...
nature.com
Exclusive: NSF stops awarding new grants and funding existing ones
US science funder also plans to screen grant applications for compliance with ‘agency priorities’.
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Reposted by Vikram Agarwal
Saganism @sagan.bsky.social · 02/05/2025
Dr. Anthony Fauci urges Americans not to accept "Normalization of Untruths".
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David Ho @davidho.bsky.social · 02/05/2025
Well, fuck! Just got a message from my university that we can no longer spend money on our NSF-funded grants. This is as good as having the grants taken away from us.
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Reposted by Vikram Agarwal
Sean Carroll @seanmcarroll.bsky.social · 02/05/2025
Short of literally launching a war, it’s hard to imagine how a foreign adversary could do more lasting damage to the US than the Trump administration is doing.
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Reposted by Vikram Agarwal
Carl Zimmer @carlzimmer.com · 02/05/2025
Time to catch up on the past week’s news about science and medicine in the US. Whew. 1/10
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Reposted by Vikram Agarwal
Dan Garisto @dangaristo.bsky.social · 01/05/2025
BREAKING: NSF has frozen all grant funding, as of yesterday. It's unclear when they will resume funding awards, or why the pause has been put in place. www.nature.com/articles/d41...
nature.com
Exclusive: NSF stops awarding new grants and funding existing ones
US science funder also plans to screen grant applications for compliance with ‘agency priorities’.
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Reposted by Vikram Agarwal
Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · 02/05/2025
The possibility that RFK Jr. is going to undermine herd immunity in the United States grows increasingly likely. This would mean that US will be responsible for starting numerous pandemics and potentially destroying the effectiveness of the entire globe’s vaccine arsenal. This is bioterrorism.
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Reposted by Vikram Agarwal
Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 23/04/2025
In what proportions is our new NIH Director a flaming ignoramus vs. a brazen liar?
Jonny Paradise 🌱
@plantparadise7
·
NIH Director Jay Bhattacharya on mRNA tech: 

"The next step is [to halt] the mRNA platform itself... the manufacturer has no idea what dose they're giving, no idea where it goes in the body, and whether they are producing off-target antigens"
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Vikram Agarwal @vagar.bsky.social · 22/04/2025
One of the toughest parts of the field of massively parallel reporter assays to measure >~thousands of elements is that there are hundreds of pubs using them, but no central repo to easily locate the results....until now! Great collab w/ Jingjing Zhao, Ilias G-S, and @nadavahituv.bsky.social!!
genome.cshlp.org
MPRAbase a Massively Parallel Reporter Assay database
An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms
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Vikram Agarwal @vagar.bsky.social · 17/04/2025
Glad I'm not the only one observing the irony of tech billionaires handing out science prizes while backing an admin that has dismantled American science. New level of #respect for Seth Rogan
pcgamer.com
Seth Rogen goes rogue at science awards show to slam tech billionaires for backing Trump: 'It's amazing how much good science you can destroy with $320 million and RFK Jr'
You invite Seth Rogen on stage, you take your chances, as the scientific community recently discovered.
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Vikram Agarwal @vagar.bsky.social · 06/04/2025
Pretty cool study... But to me it also highlights simply how releasing more historical medical records could lead to powerful scientific findings that would impact public health policy. Not fully sure the reasons the medical community isn't doing that despite being able to anonymize them...
nature.com
A natural experiment on the effect of herpes zoster vaccination on dementia - Nature
Using a natural experiment that avoids common bias concerns, this study finds that the live-attenuated shingles vaccine reduced the probability of a new dementia diagnosis within a follow-up period of...
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Reposted by Vikram Agarwal
David Corn @davidcorn.bsky.social · 02/04/2025
It’s stunning to me that the New York Times did not put the story on the bloodbath at the NIH, CDC, and FDA on its front page this morning.
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Vikram Agarwal @vagar.bsky.social · 26/03/2025
Dear America: if your daughter or son or mother or father or YOU have cancer, and there is or could be an mRNA vaccine that would treat it, are you prepared to destroy the research/tech that would save their lives? Because doing so would take your self-sabotage to unprecedented levels of stupidity..
kffhealthnews.org
Scientists Say NIH Officials Told Them To Scrub mRNA References on Grants - KFF Health News
Two senior scientists say National Institutes of Health officials advised them to remove references to mRNA vaccines in grant applications, and they fear the Trump administration will abandon a promis...
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Vikram Agarwal @vagar.bsky.social · 20/03/2025
Most bizarre article I've read in quite some time...of course, Florida is no stranger to bizarre
floridaphoenix.com
Proposal to ban mRNA vaccines in fruits & vegetables advances in Florida Senate • Florida Phoenix
The Florida Legislature for the first time Wednesday heard testimony about a measure that would prevent vaccines from being incorporated into food products. The bill (SB 196) sponsored by Sarasota Sen...
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Reposted by Vikram Agarwal
Jake Wintermute @synbio1.bsky.social · 03/03/2025
I know that the mRNA is larger than the protein it codes for but I don't believe it
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Vikram Agarwal @vagar.bsky.social · 13/03/2025
Published in today's issue! OPEN ACCESS article, FREE massive dataset, FREE code, FREE pre-trained AI/ML model. #OpenScience was a mountain of work to make this happen: check it out if you haven't already 😉
nature.com
Massively parallel characterization of transcriptional regulatory elements - Nature
Lentivirus-based reporter assays for 680,000 regulatory sequences from three cell lines coupled to machine-learning models lead to insights into the grammar of cis-regulatory elements.
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Reposted by Vikram Agarwal
Ardem Patapoutian @ardemp.bskyverified.social · 08/03/2025
Interesting! @nytimes.com still hasn’t covered any of the Stand Up for Science protests today, but they made sure to put this important news front and center online. Powerful reporting…
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Vikram Agarwal @vagar.bsky.social · 03/03/2025
Life achievement unlocked: our first cover art accepted alongside our new review on computational techniques to model lipid nanocarriers for drug delivery!
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Vikram Agarwal @vagar.bsky.social · 01/03/2025
Waiting for someone to download the 80M papers on sci-hub and train an agentic AI reasoning system to query it...would be illegal but simultaneously synthesize all of scientific knowledge as we know it into one oracle of knowledge...😈
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Reposted by Vikram Agarwal
Harmit Singh Malik @harmitmalik.bsky.social · 01/03/2025
Heartbreaking chats this week with students thinking of giving up on their dreams of getting a PhD. They worry about getting in PhD programs and careers post PhD. My suggestions: don’t be hasty, think broadly incl EU & Canada, & careers beyond traditional academia. What’re you telling your students?
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Vikram Agarwal @vagar.bsky.social · 27/02/2025
#Vibes I'm feeling these days in USA...Incubus was way ahead of their time 🫣
youtube.com
Incubus - Megalomaniac (Video Version)
YouTube video by IncubusVEVO
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Reposted by Vikram Agarwal
Stephen Floor @snf.bsky.social · 27/02/2025
Shot: first measles death in the US in a decade Chaser: March FDA meeting on flu vaccine design cancelled www.nbcnews.com/health/healt...
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Office of Mayor Michelle Wu 吳弭 @mayorwu.boston.gov · 20/02/2025
The City of Boston is leading 40+ mayors, cities, and counties in an amicus brief against the Trump Administration's drastic and illegal cuts to federal research funding—cuts that will lead to immediate job losses nationwide.
COALITION OF MAYORS ACROSS U.S. FILE AMICUS BRIEF IN OPPOSITION TO TRUMP ADMINISTRATION’S DRASTIC CUTS TO FEDERAL RESEARCH FUNDING
Led by the City of Boston, MA, City of Cleveland, OH, the Metropolitan Government of Nashville and Davidson County, TN, the Mayor of Gainesville, FL, and the Mayor of Salt Lake City, UT, over 40 mayors, cities, and counties argue that NIH cuts will cause job losses, economic disruption, and undermine U.S. competitiveness

BOSTON - Thursday, February 20, 2025 - Late yesterday, Mayor Michelle Wu co-led a coalition of Mayors from across the United States in writing and filing an amicus brief in federal district court in Boston to stop the Trump Administration's drastic and illegal cuts to federal research funding and immediate job losses in cities nationwide. Over 40 mayors, cities, and counties from across the country joined the brief. These cities are home to universities and hospitals that employ hundreds of thousands of Americans in cutting edge medical and scientific research, and the federally-funded research in these communities has made the United States the global leader in scientific discovery. The brief seeks a temporary restraining order against the Trump Administration, alongside the research universities, medical schools, hospitals, and 22 states that are plaintiffs in the three cases filed last week in federal district court.

“For decades, Congress has made a clear choice to use federally-funded research to invest in cities, build a broadly-distributed infrastructure for scientific discovery, create jobs, and drive economic growth in communities across the United States,” said Mayor Michelle Wu. “We join with cities across the country – in red states, purple states, and blue states – to stop this illegal action that will cause layoffs, lab closures, and undermine scientific progress in American cities. I thank Massachusetts Attorney General Andrea Campbell for her leadership on behalf of the research institutions of Boston.”This amicus brief is in response to the abrupt February 7, 2025 announcement by the National Institutes of Health (NIH) of an immediate reduction in funding for scientific and medical research institutions across the country. Under the NIH’s new policy, which temporarily went into effect on Monday, February 10, payments for indirect costs reimbursed to research universities would be capped at 15%, down from 30-70%. The brief makes clear that NIH funding cuts would devastate research institutions in cities across the county, cause job losses, create severe economic disruption, and undermine a critical pillar of strength and civic pride in cities across the United States. The cuts would also undermine critical medical and scientific research that residents are counting on, including cancer, diabetes, and heart disease, and jeopardize the cities’ and country’s position of global leadership on scientific advancement.
“The Gainesville community depends on this highly efficient, dependable investment of our tax dollars back into our city’s innovation economy,” said Harvey L. Ward, Mayor, City of Gainesville, Florida. “I’m glad to join other mayors in highlighting the vital role NIH funding plays in the lives of everyday hardworking American families.” 
“The breadth and diversity of this coalition highlights the devastating and widespread impact of these NIH funding changes, from Alzheimer’s research to cancer clinical trials,” said Jill Habig, Founder and CEO of Public Rights Project. “We’re proud to partner with mayors, cities, and counties in opposing this threat to critical federal funding and the health and vitality of our communities.”
On Monday, February 10th, twenty two states and associations of medical schools, hospitals, and universities, filed three related cases, and secured a temporary restraining order preventing the Trump Administration from slashing the reimbursement rates. That initial order will be revisited this week in a hearing scheduled for Feb. 21.The Public Rights Project served as amici counsel. The full list of mayors, cities and counties who joined the brief is below. 



Local Governments and Mayors



City of Boston, Massachusetts
City of Cleveland, Ohio
Harvey L. Ward, Mayor, City of Gainesville, Florida
Metropolitan Government of Nashville and Davidson County, Tennessee
Erin Mendenhall, Mayor, City of Salt Lake City, Utah
City of Alameda, California
City of Albuquerque, New Mexico 
Allegheny County, Pennsylvania
City of Baltimore, Maryland 
Emma Mulvaney-Stanak, Mayor, City of Burlington, Vermont
Township of Canton, Michigan
Town of Chapel Hill, North Carolina
City of Chicago, Illinois 
Sandra Welch, Mayor, City of Coconut Creek, Florida
City of Columbus, Ohio
City of Easthampton, Massachusetts
Daniel Biss, Mayor, City of Evanston, Illinois
City of Fairfax, Virginia
Harris County, Texas
Ravinder S. Bhalla, Mayor, City of Hoboken, New Jersey
Quinton Lucas, Mayor, Kansas City, Missouri
Indya Kincannon, Mayor, City of Knoxville, Tennessee
City of Madison, Wisconsin
Jeff Silvestrini, Mayor, City of Millcreek, Utah
Anissa Welch, Mayor, City of Milton, Wisconsin
Montgomery County, Maryland
City of New Haven, Connecticut
Dontae Payne, Mayor, City of Olympia, Washington 
Adrian O. Mapp, Mayor, City of Plainfield, New Jersey
Sue Noack, Mayor, City of Pleasant Hill, California
City of Pittsburgh and Ed Gainey, Mayor, City of Pittsburgh, Pennsylvania
City of Providence, Rhode Island 
John Clark, Mayor, Town of Ridgway, Colorado
City of Rochester, New York
City of Sacramento, California 
City and County of San Francisco, California
City of Santa Monica, California
Constantine H. Kutteh, Mayor, City of Statesville, North Carolina
Lisa Brown, Mayor, City of Spokane, Washington
Tishaura O. Jones, Mayor, City of St. Louis, Missouri 
City of St. Paul, Minnesota
Dennis R. McBride, Mayor, City of Wauwatosa, Wisconsin
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Vikram Agarwal @vagar.bsky.social · 21/02/2025
Very interesting work, congrats @anshulkundaje.bsky.social and team!!!
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Adam Bonica @adambonica.bsky.social · 20/02/2025
The DOGE firings have nothing to do with “efficiency” or “cutting waste.” They’re a direct push to weaken federal agencies perceived as liberal. This was evident from the start, and now the data confirms it: targeted agencies overwhelmingly those seen as more left-leaning. 🧵⬇️
Scatterplot titled “Empirical Evidence of Ideological Targeting in Federal Layoffs: Agencies seen as liberal are significantly more likely to face DOGE layoffs.”
	•	The x-axis represents Perceived Ideological Leaning of federal agencies, ranging from -2 (Most Liberal) to +2 (Most Conservative), based on survey responses from over 1,500 federal executives.
	•	The y-axis shows Agency Size (Number of Staff) on a logarithmic scale from 1,000 to 1,000,000.

Each point represents a federal agency:
	•	Red dots indicate agencies that experienced DOGE layoffs.
	•	Gray dots indicate agencies with no layoffs.

Key Observations:
	•	Liberal-leaning agencies (left side of the plot) are disproportionately represented among red dots, indicating higher layoff rates.
	•	Notable targeted agencies include:
	•	HHS (Health & Human Services)
	•	EPA (Environmental Protection Agency)
	•	NIH (National Institutes of Health)
	•	CFPB (Consumer Financial Protection Bureau)
	•	Dept. of Education
	•	USAID (U.S. Agency for International Development)
	•	The National Nuclear Security Administration (DOE), despite its conservative leaning (+1 on the scale), is an exception among targeted agencies.
	•	A notable outlier: the Department of Veterans Affairs (moderately conservative) also faced layoffs despite its size.

Takeaway:

The figure visually demonstrates that DOGE layoffs disproportionately targeted liberal-leaning agencies, supporting claims of ideological bias. The pattern reveals that layoffs were not driven by agency size or budget alone but were strongly associated with perceived ideology.

Source: Richardson, Clinton, & Lewis (2018). Elite Perceptions of Agency Ideology and Workforce Skill. The Journal of Politics, 80(1).
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Science Magazine @science.org · 19/02/2025
Scientists are now organizing events, called Stand Up for Science, on 7 March in Washington, D.C., and state capitals. So far, they have attracted more than 100 volunteers from some 30 states who are hoping to rally support for research as a public good. scim.ag/4328LAD
scim.ag
‘I really wanted something to happen.’ The students behind the Stand Up for Science protests
New group hopes to turn out researchers for 7 March demonstrations against Trump administration policies
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