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coffeebond007.bsky.social @coffeebond007.bsky.social · 01/08/2025

The PAL-AI paper 📑 is now available online! The improved model can predict poly(🅰️) tail-length change resulting from single-nucleotide substitutions in multiple species. doi.org/10.1038/s414...

doi.org

PAL-AI reveals genetic determinants that control poly(A)-tail length during oocyte maturation, with relevance to human fertility - Nature Communications

Gene regulation in oocytes relies heavily on poly(A) tail-length changes. Here, the authors develop PAL-AI, a neural network model that predicts tail-length changes, identifies regulatory motifs, and ...

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