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Tyler Ryan Sizemore

@tsizzle2.bsky.social
382 followers 518 following 68 posts

Scientist @thernainstitute.bsky.social | post-doc @carlsonlabyale.bsky.social | PhD @adacks.bsky.social | neuromodulation | insectophile | Former @CSHLflycourse Social Media Coordinator | #FirstGen | he/him | Opinions are my own | tylersizemore.com

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Reposted by Tyler Ryan Sizemore
John Tuthill @tuthill.bsky.social · 15h
two new preprints from Wangchu Xiang (@darbly.bsky.social, Ginty labs) about connectomic reconstruction from electron microscopy of somatosensory afferents and projection neurons in the dorsal horn of the mouse spinal cord www.biorxiv.org/content/10.6... www.biorxiv.org/content/10.6...
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Tim Mosca (he/him) @drosophilosophy.bsky.social · 11h
We finally got an NOA! The lab now has a brand new R01 from the NINDS to fund our work on synaptic biology in the olfactory system through 2031!
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Wolfgang Stein @wolfgangstein.bsky.social · 01/10/2026
Our new Research Renaissance Podcast interview with the Karen Toffler Charitable Trust is online: www.youtube.com/watch?v=hG3L... Apple Podcast - podcasts.apple.com/us/podcast/r... Spotify - open.spotify.com/show/6aVpn1S... Amazon Music - music.amazon.com/podcasts/2fd... @kavlifoundation.org
youtube.com
How the Brain Balances Flexibility and Robustness with Dr. Wolfgang Stein
YouTube video by Research Renaissance
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Amanda Moehring @flybehaviour.bsky.social · 01/10/2026
Cool new paper from @joshdubnau.bsky.social Early life social isolation primes flies for rapid neurodegeneration later in life. www.biorxiv.org/content/10.6...
biorxiv.org
Early life social isolation primes flies for more rapid TDP-43 dependent neurodegeneration later in life.
A key pathophysiological hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is loss of nuclear localization and abnormal cytoplasmic aggregation of TAR DNA-binding prote...
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The Washington Sun @washingtonsun.com · 01/10/2026
An overwhelming majority of Americans want members of Congress to stop trading individual stocks.
washingtonsun.com
Why a Popular Push to Ban Congressional Stock Trading Crashed and Burned
But is it only mostly dead?
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Alex Wild @alexwild.bsky.social · 01/10/2026
A cute little reticulated beetle, Tenomerga cinerea. This odd lineage last shared an ancestor with more typical beetles like ladybirds and scarabs nearly 300 million years ago.
Macro photo in dorsal view of an elongate tan beetle with large antennae and dark brown markings on its elytra, standing on a pure white substrate.
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Lukas Groschner @lukasgroschner.bsky.social · 29/09/2026
Single-neuron computations depend on the subcellular distribution and voltage sensitivity of ion channels. | @pnas.org #HorizonEU @erc.europa.eu (1/5) www.pnas.org/doi/10.1073/...
pnas.org
Distribution and voltage dependence of ion channels shape single-neuron computations | PNAS
Voltage-gated ion channels do not distribute evenly in the plasma membrane of a neuron; they localize to distinct domains where they govern the exc...
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Jolyon Troscianko @jtroscianko.bsky.social · 30/09/2026
🦋 Butterfly wing patterns create motion illusions that protect them from predators! Our new study (8 years in the making) is out in Nature today doi.org/10.1038/s415... @grahancock.bsky.social @esbriolat.bsky.social @scienceanna.bsky.social @lauraakelley.bsky.social @uniexecec.bsky.social
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Tessa Montague @tessamontague.bsky.social · 29/09/2026
I'm excited to share our new preprint: Generation of a transgenic cephalopod tinyurl.com/pc86jxz8 Cephalopods (cuttlefish, octopus & squid) are crazy critters that dynamically camouflage to their surroundings by changing the color, pattern, & texture of their skin, which they control w their brain.
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Debt Collective 🟥 @debtcollective.bsky.social · 28/09/2026
Hundreds of thousands, if not millions, of student debtors are being kicked off an affordable repayment plan and put into more expensive plans tomorrow. Many are trying to find payment plans that work for them. Here's the repayment calculator today.
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bioRxiv Genetics @biorxiv-genetic.bsky.social · 28/09/2026
Generation of a transgenic cephalopod www.biorxiv.org/content/10.64898/20…
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Leah Houri-Zeevi @leahhouri.bsky.social · 25/09/2026
🩸🩸🩸TODAY WE SHARE TWO MAJOR DISCOVERIES🩸🩸🩸 1. We peered into genomes and brains of the rare mosquitoes that QUIT feeding on blood and found what biting is built from 2. Humans got rid of isoleucine in their blood, malaria suffers from it, and mosquito proteomes budget for it THREADS>
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Annika Barber @annikabarber.bsky.social · 25/09/2026
🚨🚨🚨 Very urgent for many of us. I also just learned this today. Tell your friends. Tell your grant admins. 🧪
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International Society for Neuroethology @neuroethology.org · 24/09/2026
🚨 New paper out in @jexpbiol.bsky.social by Jeschke et al. "Bees exhibit behavioural flexibility to learned visual cues to prevent negative consequences during navigation in clutter" 🐝🧪 #InsectResearch #AnimalNavigation #AssociativeLearning #Cognition ↘️ doi.org/10.1242/jeb.... ↙️
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@LaBonneLaB @labonnelab.bsky.social · 24/09/2026
WaPo Editorial Board gets it right for once wapo.st/4cZhesJ
wapo.st
Opinion | Scientific research is an economic blessing. Keep Trump cronyism out.
Congress has already rebuked the president on this issue multiple times.
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Becky Johnson @entomososwin.bsky.social · 21/09/2026
I'm very excited to announce that I'll be joining the Entomology Department at Penn State University and starting a lab in the summer of 2027!!! The lab will focus on mosquito biology/physiology and mosquito-host interactions and how these impact viral transmission dynamics. More to come soon! 🎉🦟🔬
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Matt Lovett-Barron @mlovettbarron.bsky.social · 23/09/2026
Our lab's latest paper on the neurobiology of collective behavior is now published www.nature.com/articles/s41... This is the work of a great team in the lab - led by Jo-Hsien Yu, with Geoff Meyerhof, Jimjohn Milan, and Julia Napoli @nature.com @danionella.bsky.social
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Hany K. M. Dweck (هاني دويك) @dwecklab.bsky.social · 19/09/2026
After four wonderful years at the CAES, our lab is moving to TAMU Entomology (@tamuentomology). I am very excited about this new chapter. We will be hiring three postdocs to start early next year. Please contact me if you are interested.
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Joshua Weitz @joshuasweitz.bsky.social · 18/09/2026
The White House budget proposal for FY27 slash NSF funding by more than 50% and would drastically reduce support for PhDs, postdocs & investigator-initiated research. Selling something is not the same as doing something. Science is hard. This 'new golden age' won't make it easier.
US NSF announces

"Science: A New Golden Age Summit"

Washington
Discover the frontier
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Wei-Chung Allen Lee @darbly.bsky.social · 19/09/2026
Great primer from Chih-Ying Su: journals.plos.org/Plosbiology/... on a first connectomic foray into mosquitoes: journals.plos.org/plosbiology/... Go diptera #neuroskyence!
journals.plos.org
How the mosquito’s carbon dioxide sense gets an internal boost
Mosquitoes use carbon dioxide as a critical cue to sense if humans are nearby. This Primer explores a new study in PLOS Biology that reveals that carbon dioxide-sensing neurons in mosquitoes can ampli...
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Lochlan W @lochlanw.bsky.social · 17/09/2026
excited to share my first preLight summarizing such an exciting preprint! from Tjalda Falt et al. @fleyes.bsky.social Vectorial efference copy and visuomotor transformation through gap junctions prelights.biologists.com/highlights/v...
prelights.biologists.com
Vectorial efference copy and visuomotor transformation through gap junctions - preLights
To see, or not to see: fruit flies selectively suppress visual input via electrical transmission of an efference copy
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Jess Piper @piperformissouri.bsky.social · 16/09/2026
…
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Andrew Lin @andrewclin.bsky.social · 15/09/2026
We're hiring! Join us as a postdoc to study how the brain is optimised for sensory coding and memory Please spread the word! Apply at jobsite.sheffield.ac.uk/job/Research... Deadline: 5 October 2026 Learn more at: www.aclinlab.org
jobsite.sheffield.ac.uk
Research Associate: Neuroscience (2 Posts)
Research Associate: Neuroscience (2 Posts)
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Tom Kash @superkash.bsky.social · 15/09/2026
new paper out, led by @jobeneuro.bsky.social , exploring 5HT dynamics in cingulate and central amygdala, and how a history of alcohol consumption changes them! www.nature.com/articles/s41...
nature.com
Selective dysregulation of serotonin dynamics in the anterior cingulate cortex and central amygdala following binge alcohol consumption - Neuropsychopharmacology
Neuropsychopharmacology - Selective dysregulation of serotonin dynamics in the anterior cingulate cortex and central amygdala following binge alcohol consumption
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Carolina Rezaval @crezaval.bsky.social · 16/09/2026
We’re hiring two postdocs! Join the our Lab @unibirmingham.bsky.social to uncover how the brain resolves behavioural conflicts. Deadline: 22 September 2026 @wellcometrust.bsky.social Please share! www.rezavallab.org
jobs.ac.uk
Research Fellow (Postdoctoral) at University of Birmingham
Apply for the Research Fellow (Postdoctoral) role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now.
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Carolina Rezaval @crezaval.bsky.social · 16/09/2026
We’re hiring two postdocs! Join our Lab @unibirmingham.bsky.social to uncover how the brain resolves behavioural conflicts. Deadline: 22 September 2026 @wellcometrust.bsky.social Please share! www.rezavallab.org
rezavallab.org
Home
​ ​Animals must make crucial behavioural choices on a minute by minute basis to survive in a changing environment. A long-standing enigma is, how are alternative options evaluated in the brain...
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Kristyn Lizbinski @kristyn-lizbinski.bsky.social · 16/09/2026
New lab website 😎 lizbinskilab.com
lizbinskilab.com
Lizbinski Lab
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Sweta Agrawal @hokuba.bsky.social · 16/09/2026
The Agrawal lab has published its first paper! "Sticking the landing: leg mechanosensory feedback coordinates the transition from flight to landing" www.biorxiv.org/content/10.6... This project was led by a technician in the lab, Tse-Wei (Wayne) Kuo. Brief 🧵on what we found
agrawal-lab-workspace.slack.com
Slack
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The Tennessee Holler @thetnholler.bsky.social · 15/09/2026
Safe to say the people of Kentucky are not being represented properly
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PLOS Biology @plosbiology.org · 11/09/2026
CO2 is an important cue used by #mosquitoes when searching for a human blood meal. @darbly.bsky.social @megyounger.bsky.social &co show that the wiring of #neurons that sense CO2 differs from that in #Drosophila, allowing robust detection of this key host cue @plosbiology.org 🧪 plos.io/4cFCPpV
Feedforward connectivity of maxillary palp glomeruli. Top left: Schematic with feedforward OSN-to-PN connections highlighted. Top right: Dendrograms (flattened 2D representations of the 3D dendritic arbor preserving distance information) of uPNs and their incoming feedforward synapses from OSNs. * denotes branch leading to soma, and arrow denotes branch leading to the inner antennocerebral tract (iACT). (top) uPN cable length, glomerular volume, and cable density. Scale bar 100 µm. Bottom left: Coronal view of uPN reconstructions. Scale bar 25 µm. Bottom right: Axograms (flattened 2D representations of the 3D axonal arbor preserving distance information) of representative OSNs with their feedforward synapses to uPNs shown as colored dots. Scale bar 25 µm.
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Meg Younger @megyounger.bsky.social · 11/09/2026
Excited to share this work from @darbly.bsky.social's lab and my lab with @davidhildebrand.bsky.social @briandepasquale.bsky.social and many others! It turns out that the sensory neurons that detect CO2 in Aedes aegypti mosquitoes have lots of recurrent connections! 🦟👃🌟
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Andrew Dacks @adacks.bsky.social · 15/09/2026
Know an outstanding PhD student whose thesis work was on Drosophila? If so, please consider nominating them for the Larry Sandler award! The nomination and eligibility information are at genetics-gsa.org/awards/larry.... The deadline is November 12th.
genetics-gsa.org
Larry Sandler Award - Genetics Society of America
The Larry Sandler Award was established in 1988 by the colleagues, friends, and students of Dr. Larry Sandler after his untimely death in 1987. The award serves to honor Dr. Sandler for his many contr...
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John Tuthill @tuthill.bsky.social · 14/09/2026
a good summary of how we got here and what it means. i would add is that everyone who works with the fly connectome datasets knows that they all far from "complete". each one, though monumental, has major reconstruction/annotation issues, not to mention the lack of a peripheral nervous system.
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Anu @nofirstorder.bsky.social · 08/09/2026
A legendary Medicare fraudster almost slipping up on illegal PAC coordination is pure brand consistency.
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Secretary of Defense Rock @sodrock.bsky.social · 08/09/2026
Amazing how even the Republicans that are supposed to be “normal” are complete psychopaths
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Jan M. Ache @jan-ache.bsky.social · 08/09/2026
I am extremely excited - or should I say rather chuffed? - to share that I am joining the University of Oxford @ox.ac.uk as Associate Professor of Animal Behaviour in the Department of Biology @biology.ox.ac.uk and as a Fellow of Merton College.
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Max Kozlov @maxkozlov.bsky.social · 04/09/2026
🚨 The NIH is moving to transfer hundreds of millions of dollars in infectious-disease research projects to the DOD under a secret 10-year pact. Here’s what’s happening inside “Operation Prevailing Edge” 🧵👇 www.nature.com/articles/d41...
nature.com
Revealed: inside the US military's plan to tap huge sums from the NIH
An agreement paves the way for hundreds of millions of dollars’ worth of projects to be transferred from the NIH’s institute for infectious diseases to the Department of Defense.
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Max Kozlov @maxkozlov.bsky.social · 04/09/2026
Under pressure, the DOD just released the text of its secret 10-year agreement with the NIH. Here are the biggest revelations from the document 🧵
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Champalimaud Research @champalimaudr.bsky.social · 03/09/2026
🧠Ever wonder how the brain turns a taste into the decision to eat – or not? For the 1st time @ribeirocarlitos.bsky.social team at @champalimaudf.bsky.social and their collaborators have mapped the complete neural circuitry behind an animal’s feeding decisions. 👉 www.fchampalimaud.org/news/bluepri...
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Journal of Experimental Biology @jexpbiol.bsky.social · 02/09/2026
Read the full research by @florisvanbreugel.bsky.social at doi.org/10.1242/jeb....
Screenshot of PDF of the Research Article, Wind history shapes olfactory search response in free-flying Drosophila melanogaster, by Jaleesa Houle, Austin P. Lopez and Floris van Breugel. The publishing information states: © 2026. Published by The Company of Biologists | Journal of Experimental Biology (2026) 229, jeb252635. doi:10.1242/jeb.252635. The first sentence of the abstract reads: 'The ability of flying insects to locate distant food and mates by tracking odor plumes through turbulent and unsteady flow represents a remarkable feat of sensorimotor integration'.
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Journal of Experimental Biology @jexpbiol.bsky.social · 02/09/2026
Fruit flies react instantaneously when blown about by gusts of wind to get back on course, but they also recall recent wind conditions when tracking an odour, which shapes their search as they pursue the source of an attractive scent @florisvanbreugel.bsky.social doi.org/10.1242/jeb....
A montage of flying fruit flies. Photo credit: Floris van Breugel.
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 26/08/2026
Pro tip: Most of these @dshb-antibodies.bsky.social Abs are documented in dozens of publications and are also substantially cheaper.
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Crystal Rogers, PhD @rogerslabucd.bsky.social · 28/08/2026
We have lived in Davis for 7 years and last night was the first time I have ever gone to watch the bats come out. We were gifted with an amazing sunset too! It was amazing! Huge props to Yolo Basin Foundation for a fantastic tour and event. 🦇 🌅 1/
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Neurofrontiers @neuro-frontiers.bsky.social · 28/08/2026
Lead is still bad for your brain. neurofrontiers.blog/why-lead-is-... #publichealth #lead #brainhealth #health
neurofrontiers.blog
Why lead is (still) bad for your brain - Neurofrontiers
Wait, wasn't this solved by the Romans? Anyway, my grandma ate lead paint and she was totally fine.
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MwahahahahahadScientist @mads100tist.bsky.social · 29/08/2026
Do you work with microscopy images and segment to quantify or track? Do you study cell biology? development? Gather round! Let me tell you about FOCUS-3D, a segmentation algorithm that is fast, accurate and can be used on any model. We used it here to study zebrafish development. 🧪 (thread)
biorxiv.org
FOCUS‑3D: Robust, generalizable volumetric cell segmentation for three‑dimensional fluorescence microscopy
Understanding how cells establish spatial organization within tissues is a fundamental question in life sciences. While modern three-dimensional fluorescence microscopy captures large-volume tissue ar...
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Anita Devineni @anitadevineni.bsky.social · 29/08/2026
The ratio on this is hilarious Spare yourself this stream of narcissism and condescension that willfully misrepresents what unionization actually does (e.g: "The value of a good postdoctoral fellowship is not to be measured in salary but in the opportunity to learn at the feet of, yes, a master.")
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Science Magazine @science.org · 29/08/2026
When stressed, this comb jelly reverts to a larval form, then matures again when favorable conditions return. Learn more: scim.ag/4gmdt2J #ScienceMagArchives
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Elinne Becket, PhD @bielleogy.bsky.social · 29/08/2026
Pro-tip: If you print a Word doc to PDF, you lose most/all accessibility details. If you export/Save A Copy as PDF, there's an option to keep Accessibility features.
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Tyler Ryan Sizemore @tsizzle2.bsky.social · 29/08/2026
Great new pub from the Asahina lab and co! Congrats everyone! www.cell.com/current-biol...
cell.com
Cellular and functional dissection of the octopaminergic and tyraminergic system in the Drosophila brain
Palacios Castillo and Fajner et al. establish a comprehensive split-GAL4 toolkit to selectively manipulate octopaminergic/tyraminergic (OA/TA) neurons in Drosophila. They demonstrate that distinct OA/...
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SK Winnicki, PhD 🏳️‍⚧️ @skwinnicki.bsky.social · 29/08/2026
Overworks all parties to the point of burnout far too often, leaving the system unstable and vulnerable to fascist takeover. And of course too hierarchical even at upper levels, leaving mentees at the mercy of mentors' insecurities and imposter syndrome.
static.klipy.com
Anakin Skywalker: This is outrageous! It's unfair!
Alt: Scene from Revenge of the Sith where the young hotshot Assistant Professor Anakin Skywalker is denied early promotion to tenure and he makes it everyone's problem, including his padawan mentee and the full professors in his department. In other words, the scene where Anakin is denied the rank of master and yells "This is outrageous! It's unfair!" at the Jedi Council.
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