Sign in

Tamara Basta

@tamarabasta.bsky.social
107 followers 107 following 10 posts

Assistant professor at Paris-Saclay University & at Institute for integrative biology of the cell (I2BC). Interested in Archaea, hyperthermophiles, DNA topology, topoisomerases.

PostsRepliesMedia
Reposted by Tamara Basta
Vicky Lioy @vslioy.bsky.social · 14/02/2026
📢 Save the date! #Biophychrom2027 will take place at Paris-Saclay in July 2027. More details coming soon!
065
Reposted by Tamara Basta
biophychrom.bsky.social @biophychrom.bsky.social · 05/02/2026
Mark your calendars for the next incarnation of the Biology and Physics of the Prokaryotic Chromosome meeting to be held in Paris on July 6-9, 2027. See the web site for further information biophychrom2027.sciencesconf.org
biophychrom2027.sciencesconf.org
The Biology and Physics of Prokaryotic Chromosomes VIII - Sciencesconf.org
Presentation
01111
Reposted by Tamara Basta
Buzz Baum @buzzbaum.bsky.social · 23/01/2026
A reminder to sign up for the 2026 EMBO archaeal meeting im Cambridge: meetings.embo.org/event/26-arc.... Registration is open. We are looking forward to hosting you!
meetings.embo.org
Molecular Biology of Archaea: Life Through the Prism of Archaea
In 1977, Woese and colleagues revealed Archaea as a distinct domain of life. Building on this insight, the discovery of Asgard archaea has strengthened the view that many hallmarks of eukaryotic cell…
04035
Reposted by Tamara Basta
BejaLabTechnion @bejalab.bsky.social · 26/01/2026
Iron Sulfides Produced by Thermococcales: An Iron Detoxification Mechanism enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...
enviromicro-journals.onlinelibrary.wiley.com
Iron Sulfides Produced by Thermococcales: An Iron Detoxification Mechanism
Thermococcales, archaea from hydrothermal vents, promote iron sulfide precipitation, enabling survival in iron-rich environments. Some cells become encrusted in pyrite and do not survive mineralizati...
085
Reposted by Tamara Basta
Svetlana Dodonova @dodonova-sveta.bsky.social · 16/12/2025
Calling all archaeal enthusiasts! 🔬🔥 From molecular machines to microbial communities, Archaea never fail to surprise us! We are excited to announce the 2026 EMBO Workshop on the Molecular Biology of Archaea, 6–10 July in Cambridge, UK! Sign up here: meetings.embo.org/event/26-arc... #ArchaeaSky
24327
Reposted by Tamara Basta
Buzz Baum @buzzbaum.bsky.social · 16/12/2025
Are you a long-time fan of Archaea, an extremophile-phile, or are you simply curious? Either way, we have good news. We’re delighted to announce the 2026 EMBO Workshop on Archaea, 6–10 July. Sign up: meetings.embo.org/event/26-arc... We look forward to seeing you in Cambridge, UK. Please repost!
meetings.embo.org
Molecular Biology of Archaea: Life Through the Prism of Archaea
In 1977, Woese and colleagues revealed Archaea as a distinct domain of life. Building on this insight, the discovery of Asgard archaea has strengthened the view that many hallmarks of eukaryotic cell…
27850
Reposted by Tamara Basta
Antoine Hocher @ahocher.bsky.social · 16/12/2025
Are you a long-time fan of Archaea, an extremophile-phile, or are you simply curious? Either way, we have good news. We’re delighted to announce the 2026 EMBO Workshop on Archaea, 6–10 July. Sign up: meetings.embo.org/event/26-arc... We look forward to seeing you in Cambridge, UK Please repost!!
meetings.embo.org
01310
Reposted by Tamara Basta
Naomichi Takemata @naomichitakemata.bsky.social · 11/12/2025
Please also check out the excellent complementary work from Tamara Basta @tamarabasta.bsky.social and Laura Baranello’s group. www.biorxiv.org/content/10.6...
biorxiv.org
Localised activity of reverse gyrase at gene regulatory elements
DNA topoisomerases are essential enzymes found in all cells, where they regulate DNA supercoiling. Reverse gyrase (RG) is a unique type of topoisomerase that introduces positive supercoils into DNA an...
042
Reposted by Tamara Basta
Naomichi Takemata @naomichitakemata.bsky.social · 11/12/2025
Delighted to share our latest preprint on reverse gyrase, a unique topoisomerase found exclusively in thermophiles! www.biorxiv.org/content/10.6...
biorxiv.org
Reverse gyrase and 3D genome architecture suppress hyperthermophile genome instability arising from horizontal gene transfer
Reverse gyrase (Rgy), a distinctive topoisomerase conserved in all hyperthermophiles, has the unique ability to introduce positive DNA supercoils. It has long been hypothesized that Rgy overwinds geno...
2157
Tamara Basta @tamarabasta.bsky.social · 11/12/2025
Delighted to share our new preprint: www.biorxiv.org/content/10.6... We address a longstanding question about the role of the topoisomerase reverse gyrase in hyperthermophiles. Great collaboration with Baranello and @tobiaswarnecke.bsky.social groups. #Archaeasky #Microsky
biorxiv.org
Localised activity of reverse gyrase at gene regulatory elements
DNA topoisomerases are essential enzymes found in all cells, where they regulate DNA supercoiling. Reverse gyrase (RG) is a unique type of topoisomerase that introduces positive supercoils into DNA an...
21512
Reposted by Tamara Basta
Vicky Lioy @vslioy.bsky.social · 08/12/2025
Open FSEP position in our team 📣 Nous recrutons un/e Ingénieur/e d’étude en biologie. Profil : être titulaire d’un poste permanent au CNRS (IE) et avoir envie d’étudier la chromatine bactérienne 😉 Date limite : jeudi 15 janvier. Détails et candidature ici : mobiliteinterne.cnrs.fr/ords/afip/ow...
mobiliteinterne.cnrs.fr
Détails de la fonction choisie
036
Reposted by Tamara Basta
LSI-Exeter @lsiexeter.bsky.social · 25/11/2025
Last chance to apply for one of the LSI PhD projects intake Sept 2026! Deadline tomorrow, 26.11.2025, noon. www.exeter.ac.uk/research/ins... @exeter.ac.uk @lsiexeter.bsky.social
046
Reposted by Tamara Basta
Daniela Barillà @danielabarilla.bsky.social · 09/11/2025
📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social www.findaphd.com/phds/project... 📅 January 7, 2026 Please RP🙏thx!
Archaeal cells whose DNA has been stained with a blue dye. Zoomed-in images of mutant cells that display chromosome segregation defects.High-resolution images of DNA-protein complexes obtained with atomic force microscopy. Upon binding, the protein bridges distant sites, forming loops.
23833
Reposted by Tamara Basta
forterre @pforterre.bsky.social · 06/11/2025
A very nice review on my favorite archaea. The Thermococcales as a model system: historical perspectives and emerging tools | Journal of Bacteriology journals.asm.org/doi/10.1128/...
journals.asm.org
The Thermococcales as a model system: historical perspectives and emerging tools | Journal of Bacteriology
The exploration of life in extreme environments gained prominence with Thomas Brock’s “Life at High Temperatures” (1), and his subsequent isolation of Thermus aquaticus with Hudson Freeze in 1969 (2) ...
054
Reposted by Tamara Basta
Dame lab at Leiden University @damelab.bsky.social · 06/11/2025
New article online: Modulation of archaeal hypernucleosome structure and stability by Mg2+ In this work, we dissect the effects of Mg2+ on hypernucleosomes formed by the canonical histones from M. fervidus (HMfA and HMfB) and T. kodakarensis (HTkA and HTkB). www.sciencedirect.com/science/arti...
sciencedirect.com
Modulation of archaeal hypernucleosome structure and stability by Mg2+
DNA-wrapping histone proteins play a central role in chromatin organization, gene expression and regulation in most eukaryotes and archaea. While the …
1159
Reposted by Tamara Basta
Yann Moalic @drym.bsky.social · 05/11/2025
The Thermococcales as a model system: historical perspectives and emerging tools | Journal of Bacteriology journals.asm.org/doi/10.1128/...
journals.asm.org
The Thermococcales as a model system: historical perspectives and emerging tools | Journal of Bacteriology
The exploration of life in extreme environments gained prominence with Thomas Brock’s “Life at High Temperatures” (1), and his subsequent isolation of Thermus aquaticus with Hudson Freeze in 1969 (2) ...
052
Reposted by Tamara Basta
Tung Le @tunglejic.bsky.social · 21/10/2025
002
Reposted by Tamara Basta
Clément Madru @cryoclem.bsky.social · 13/10/2025
Our work on ribosome hibernation in archaea is out! We identified Hib, a new hibernation factor broadly distributed across archaea. Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1 (1/🧵)
35522
Reposted by Tamara Basta
STCmicrobeblog @stcmicrobeblog.bsky.social · 12/10/2025
ribosomologists take note 👇 archaeal ribosome hibernation factors aRDF, Dri, ...and now: Hib (see ALT) #Archaea #ArchaeaSky
c. Hib 3D structure. The N-terminal domain of Hib (1-269) is made up of four CBS domains. Two CBS domains
interacts through their beta-sheets to form a bateman module. Two bateman modules interact to form a disk-like
structure defined as parallel CBS module in51. Each CBS domain consists of three-standed (two parallel and one
anti-parallel) b-sheet with two a-helices52. In domains 2,3 and four the first beta strand is less well defined and
extended, as already mentionned in other CBS-domain containing structures. One long loop is inserted between
a8 and b10 of the third CBS domain. The C-terminal domain (272-387) has the babbba topology found in all
bacterial HPF/RaiA-like structures. The five last residues are not visible in the cryo-EM map.
0105
Reposted by Tamara Basta
The Daum Lab @daumlab.bsky.social · 06/10/2025
Out in Science Advances: Our #cryoEM structure of HFTV1, a virus infecting the halophile #archaea. *First full atomic structure (containing all structural proteins) of any tailed virus!* Congrats and thanks to all co-authors and our fantastic collaborators! www.science.org/doi/10.1126/...
science.org
Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail
This structure of an archaeal tailed virus (arTV) provides detailed insights into arTV assembly and infection mechanisms.
012852
Reposted by Tamara Basta
Tung Le @tunglejic.bsky.social · 07/10/2025
011
Reposted by Tamara Basta
SFBBM @sfbbm.bsky.social · 07/10/2025
Du 2 au 5 décembre 2025, Université Paris-Cité Congrès « Enzymes, Proteolysis & Metabolism at the crossroads of Biochemistry », premier congrès commun de trois Groupes Thématiques de la SFBBM. gts-sfbbm-2025.sciencesconf.org?lang=fr
gts-sfbbm-2025.sciencesconf.org
Enzymes, Proteolysis & Metabolism at the crossroads of Biochemistry - Sciencesconf.org
Présentation
021
Reposted by Tamara Basta
Tobias Warnecke @tobiaswarnecke.bsky.social · 29/09/2025
Become my colleague @oxfordbiochemistry.bsky.social ! 2 Associate Professorships in the areas of - prokaryotic/eukaryotic microbiology - metabolism my.corehr.com/pls/uoxrecru...
my.corehr.com
Job Details
13043
Reposted by Tamara Basta
Daniela Barillà @danielabarilla.bsky.social · 19/09/2025
#BioPhyChrom25 gala dinner at the 14th century #Hospitium venue in York, and @agnesnoy.bsky.social talk. Lots of discussion and ideas for BioPhyChrom2027… Great vibes and atmosphere! @biophychrom.bsky.social @damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social 🧬
0126
Reposted by Tamara Basta
Biochemical Society @biochemsoc.bsky.social · 19/09/2025
That’s a wrap for The Biology and Physics of Prokaryotic Chromosomes VII 2025. A big thank you to all those who attended 🧪 #BioPhyChrom2025 #BiochemEvents
Group photo
0289
Reposted by Tamara Basta
Vicky Lioy @vslioy.bsky.social · 19/09/2025
#Biophychrom2025 is over, but we spent four exciting days discussing the biology and physics of prokaryotic chromosomes. Congratulations to all the attendees for making this conference a success. @biochemsoc.bsky.social @danielabarilla.bsky.social @graingerlab.bsky.social @damelab.bsky.social
092
Reposted by Tamara Basta
Daniela Barillà @danielabarilla.bsky.social · 18/09/2025
With evidence attached 😊 #BioPhyChrom2025 @biochemsoc.bsky.social @biophychrom.bsky.social @damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @lauraspagnolo.bsky.social @tamarabasta.bsky.social
0124
Reposted by Tamara Basta
Daniela Barillà @danielabarilla.bsky.social · 13/09/2025
The countdown for #BioPhyChrom2025 is nearly over: -2 days to go… What a fête of chromosome biology & physics!🧬 Safe journey everyone! ✈️🚂 @vslioy.bsky.social @damelab.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social @biophychrom.bsky.social www.eventsforce.net/biochemsoc/f...
Front entrance to York Minster cathedral with a blue sky background.
083
Reposted by Tamara Basta
Dame lab at Leiden University @damelab.bsky.social · 15/09/2025
Tomorrow is the start of Biology and Physics of Prokaryotic Chromosomes VII. Great speakers and participants. Excellent support by the Biochem. Society. @biochemsoc.bsky.social @danielabarilla.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @damelab.bsky.social #BioPhyChrom2025
022
Reposted by Tamara Basta
Daniela Barillà @danielabarilla.bsky.social · 02/07/2025
York calling! 📣 🧬🧬🧬 Join us at www.biochemistry.org/events-and-t... ⏳⏰ Early bird deadline approaching soon, 16 July! Do not miss out! Half of the talks selected from abstracts. @damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social @biophychrom.bsky.social
View of a street in York with old houses on both sides and the towers of York Minster in the background.
015
Reposted by Tamara Basta
Laura Eme @lauraeme.bsky.social · 22/06/2025
Excited to share our new paper in @cellreports.bsky.social that reshapes our understanding of chromosome organization's deep evolutionary roots! Our work dives into the origins of the machinery that structures our very genomes. 🔗: doi.org/10.1016/j.ce... #Genomics #Evolution #CellBiology #LECA
418374
Reposted by Tamara Basta
Daniela Barillà @danielabarilla.bsky.social · 11/06/2025
Chromosome Enthusiasts, join us at The Biology & Physics of Prokaryotic Chromosomes 🧬! Friendly community, fantastic speakers line-up, grant writing session for ECRs. Early-bird deadline approaching soon. @damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biophychrom.bsky.social
Flyer advertising The Biology and Physics of Prokaryotic Chromosome conference that will be held in York, 16-19 September 2025.
199
Reposted by Tamara Basta
Hiro Imachi @hiro-imachi.bsky.social · 04/06/2025
Would you like to work with us? At JAMSTEC, we are recruiting postdoctoral researchers through the Young Research Fellow program. This program allows fellows to independently pursue their own research projects. www.jamstec.go.jp/recruit/e/jy...
jamstec.go.jp
JAMSTEC Young Research Fellow (JYRF) | JAMSTEC - JAPAN AGENCY FOR MARINE-EARTH SCIENCE AND TECHNOLOGY
JAMSTEC Young Research Fellow (JYRF)
01013
Reposted by Tamara Basta
Dina Grohmann @curiousdina.bsky.social · 27/05/2025
Friendly reminder for all people who love their thermophilic microbe friends: early bird registration for the Thermophiles conference in Münster/GER in September is open until June 1st. Don't miss out www.uni-muenster.de/Thermophiles...
uni-muenster.de
Thermophiles 2025
041
Reposted by Tamara Basta
Daniela Barillà @danielabarilla.bsky.social · 26/05/2025
#ArchaeaSky #MicroSky
0112
Reposted by Tamara Basta
Svetlana Dodonova @dodonova-sveta.bsky.social · 26/05/2025
And big thanks of course to all involved: the Quail lab @embl.org, and the @damelab.bsky.social
041
Reposted by Tamara Basta
Vicky Lioy @vslioy.bsky.social · 16/05/2025
Come on! You still have time to register!
022
Reposted by Tamara Basta
Archaea Power Hour @archaeapowerhour.bsky.social · 12/05/2025
Think you're under pressure? Marion Illartin will close out our last APH session of the semester by telling us about her multidisciplinary approach to characterize how pressure regulates the SurR transcription factor in everyone's favorite barophile, Thermococcus barophilus!! Zoom in on May 14th!
023
Reposted by Tamara Basta
Archaea Power Hour @archaeapowerhour.bsky.social · 12/05/2025
In just 2 days on WEDNESDAY, May 14th at 10 AM EST / 4 PM CET, @fabaiwu.bsky.social will kick off our last spring APH session by telling us about his new research investigating the evolution of DNA replication machineries from Archaea to Eukaryotes!!! Visit our website (link in bio) for more info!
186
Reposted by Tamara Basta
Antoine Hocher @ahocher.bsky.social · 22/04/2025
Excited to announce the EMBO Conference: Molecular Biology of Archaea (MBoA) 2026! Join us in Cambridge, UK, from 6–10 July 2026 for the only international meeting dedicated entirely to Archaea.
22516
Reposted by Tamara Basta
Tobias Warnecke @tobiaswarnecke.bsky.social · 11/04/2025
Join us in Catalonia to discuss chromatin evolution across the tree of life and from all angles (metabolism, synthetic chromatin, you name it!) meetings.embo.org/event/24-evo...
meetings.embo.org
EvoChromo: Evolutionary approaches to research in chromatin
Chromatin is the complex of DNA, RNA and protein that is found making up the chromosomes in eukaryotic cells. Chromatin is essential for proper genome function and is involved in chromosome segregati…
01811
Reposted by Tamara Basta
Arthur Charles-Orszag @acharlesorszag.bsky.social · 08/04/2025
🚨 Tune in this Wednesday for more exciting archaea science!
054
Reposted by Tamara Basta
Thibaut Brunet @thibautbrunet.bsky.social · 03/04/2025
Striking new study from @archaeon-alex.bsky.social's lab just out in @science.org on multicellular development induced by compression in Archaea: www.science.org/doi/10.1126/...
science.org
Tissue-like multicellular development triggered by mechanical compression in archaea
The advent of clonal multicellularity is a critical evolutionary milestone, seen often in eukaryotes, rarely in bacteria, and only once in archaea. We show that uniaxial compression induces clonal mul...
6343134
Reposted by Tamara Basta
Nika Pende @nikapende.bsky.social · 01/04/2025
Nice article about data sharing and community building in Archaeal research 🥰 @archaeabio.bsky.social @archaeapowerhour.bsky.social #ArchaeaSky
0134
Reposted by Tamara Basta
Malcolm White @mfwhite2.bsky.social · 31/03/2025
www.findaphd.com/phds/project... A funded PhD studentship is available for a joint project between my lab and @andreashaag.bsky.social @uniofstandrews.bsky.social
findaphd.com
Harnessing Bacterial Viruses to Combat Antibiotic-Resistant Infections at University of St Andrews on FindAPhD.com
PhD Project - Harnessing Bacterial Viruses to Combat Antibiotic-Resistant Infections at University of St Andrews, listed on FindAPhD.com
0512
Reposted by Tamara Basta
Antoine Hocher @ahocher.bsky.social · 22/03/2025
The MIMIC lab is hiring a Postdoctoral Research Associate to join my team at @Cambridge_Uni! Exploration and engineering DNA-mimicking proteins (wet-lab position.) 🧬 Details: www.jobs.cam.ac.uk/job/50652/ Please get in touch / circulate !
jobs.cam.ac.uk
Research Associate (Fixed Term) - Job Opportunities - University of Cambridge
Research Associate (Fixed Term) in the Department of Genetics at the University of Cambridge.
01320
Reposted by Tamara Basta
Daniela Barillà @danielabarilla.bsky.social · 30/03/2025
📣 If you work on mobile DNA 🧬, you cannot miss this meeting. #Microsky #Phagesky #Archaeasky #PlasmidSky 🧪🧬🦠
073
Reposted by Tamara Basta
SFBBM @sfbbm.bsky.social · 27/03/2025
🏆Félicitations à Akandé EYITAYO, lauréat du prix du meilleur article SFBBM du mois de mars pour son article paru dans Cell Death Discovery : The membrane insertion of the pro- apoptotic protein Bax is a Tom22-dependent multi-step process: a study in nanodiscs.
021
Reposted by Tamara Basta
Université Paris-Saclay @univparissaclay.bsky.social · 24/03/2025
L'UPSaclay se mobilise ses dispositifs d’accueil de scientifiques internationaux au profit des chercheuses et chercheurs étasuniens qui souhaiteraient la rejoindre. tinyurl.com/yc77jbjf
tinyurl.com
L’Université Paris-Saclay se mobilise pour accueillir des scientifiques américains en lien avec ses homologues français et européens
L'Université Paris-Saclay, extrêmement préoccupée par les décisions de la nouvelle administration étasunienne, et notamment celles ayant trait à la science, la recherche et à la liberté académique, pi...
1158
Reposted by Tamara Basta
Daniela Barillà @danielabarilla.bsky.social · 20/03/2025
And this is a sneak peek 👀 of the 14th century venue for the meeting final dinner. www.biochemistry.org/events-and-t...
River Ouse in the foreground and The Hospitium venue in the York museum gardens.
031