iiinova — where your digital self keeps evolving

Clément Madru @cryoclem.bsky.social · 12/06/2026

Merci @xpolytechnique.bsky.social pour le coup de projecteur sur notre étude ! 🔬 Comment les ribosomes des archées hibernent-ils ? Réponse ici :

polytechnique.edu

Comment les ribosomes des archées « hibernent » - École polytechnique, éco…

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Clément Madru @cryoclem.bsky.social · 05/05/2026

Happy to share our latest paper: www.nature.com/articles/s41... Great collaboration with @ifremer.bsky.social, @cbitoulouse.bsky.social & @pasteur.fr. Studying stress in P. abyssi with near-native, minimally purified ribosomes, we identified HibA, a new hibernation factor widespread in Archaea.

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Clément Madru @cryoclem.bsky.social · 15/01/2026

Sharing this figure from the Koonin lab: www.nature.com/articles/s41... Worth printing large and framing

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Clément Madru @cryoclem.bsky.social · 13/10/2025

Our work on ribosome hibernation in archaea is out! We identified Hib, a new hibernation factor broadly distributed across archaea. Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1 (1/🧵)

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Clément Madru @cryoclem.bsky.social · 30/01/2025

First ribosome purification using poly-lysine beads (RAPPL, developed by @djuranoviclab.bsky.social & collaborators: www.biorxiv.org/content/10.1...). Full process—from lysis to grid prep—in just 3 hours. Look how pretty it is (even if a bit too diluted)! This is a game-changer🚀.

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Reposted by Clément Madru

Schmitt-Mechulam Lab @tbioc.bsky.social · 16/01/2025

We are pleased to share our work on the evolution of translation initiation now published in Nature Communications. Take a look at leaderless mRNAs and eS26 in the small ribosomal subunit of Saccharolobus solfataricus. rdcu.be/d5pgg

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