BOSTON, MA [Sept. 23, 2026] — Our understanding of how cells interact with each other has been driven for decades by the central concept of receptor-mediated

The 21st International Aegean Conference on Innate Immunity showcased advances that position innate immunity as a multiscale regulatory system integrating environmental, metabolic, epigenetic and gene...

During latent pulmonary cryptococcal infection, Zheng et al. show that TH2-driven STAT6 signaling in monocyte-derived myeloid cells suppresses extracellula

T cells are often weakly responsive to tumor self-antigens because of central tolerance, constraining their ability to eliminate tumors. We exploited mechanical force to engineer a weakly reactive T c...

Dr. Letai will serve as NCI’s 18th director.

17β-oestradiol establishes an anti-ferroptotic state in female kidney tubules.

YouTube video by Ludwig Cancer Research

NLRP3 inflammasome activation is critical for the induction of protective immunity, but molecular insights are still lacking. Here, the authors express NLRP3 variants targeted to different cellular lo...

Proteasomal degradation of cellular proteins generate defence peptides constitutively and in response to bacterial infection. Such peptides might provide a source of natural antibiotics that...

Circadian medicine, or chronotherapy, seeks to improve drug efficacy based on individuals’ circadian rhythms. Here, the authors combine principles of tissue engineering and synthetic biology to create...

Casey et al. explore the basic mechanisms of mitochondrial superoxide production and its impact on interleukin-1β production in LPS-treated macrophages.

Casey et al. explore the basic mechanisms of mitochondrial superoxide production and its impact on interleukin-1β production in LPS-treated macrophages.

The Institut Pasteur, a research organization which for more than 130 years has been committed to tackling infectious diseases, sharing knowledge and defending science, has decided to leave X because ...