DURHAM, N.C. – The Burroughs Wellcome Fund is pleased to announce the recipients of the 2026 Investigators in the Pathogenesis of Infectious Disease (PATH) awards, recognizing assistant professor-leve...

Author summary The immune system uses specialized sensors called inflammasomes to detect infection and trigger protective responses. These responses are carried out by enzymes known as caspases, which...

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Inflammasomes are multiprotein signaling platforms that activate inflammatory caspases to induce pyroptosis. In humans, canonical inflammasomes activate CASP1, which cleaves the pore-forming protein g...

Hi! I’m Liz Neeley and I’m glad you’re here. Making Sense of It All is an outlet for my work at Liminal, which focuses on sensemaking in a noisy and complicated world. I built Liminal as an antidote t...

The ability to study proteins in their native cellular context is crucial to our understanding of biology. In this work, we report a technology for intracellular protein editing, drawing from split in...

Metabolism and post-translational modifications (PTMs) are intrinsically linked and the number of identified metabolites that can covalently modify proteins continues to increase. This metabolism/PTM ...

Synthetic inhibitors of the serine protease DPP9 activate the related NLRP1 and CARD8 inflammasomes and stimulate powerful innate immune responses. Thus, it seems plausible that a biomolecule similarl...

Proteintech is offering a $1000 award for the most outstanding lab manager.