iiinova — where your digital self keeps evolving

Reposted by Elvira Boršić Mlinarič

CTGCT (Centre for the Technologies of Gene and Cell Therapy) @ctgct.bsky.social · 25/09/2025

#CTGCT Science Talks are back! This time we have a talk open to everyone by dr. Iva Hafner Bratkovič from the Department of Synthetic Biology and Immunology at the @kemijski.bsky.social. Her talk is titled "Inflammasome-inspired cancer immunotherapy" Join us! forms.office.com/e/KJTTsMyETk #Webinar

011

Reposted by Elvira Boršić Mlinarič

Jonathan Kagan @jkagan1.bsky.social · 27/05/2025

NLRP3 inflammasomes can assemble on most organelles. A beautiful study by Hafner et al demonstrate the flexibility of organelles that can support inflammasome activation. Kudos to the authors on an intriguing study. www.nature.com/articles/s41... @ivahb.bsky.social @elvirab.bsky.social

nature.com

Clustering of NLRP3 induced by membrane or protein scaffolds promotes inflammasome assembly - Nature Communications

NLRP3 inflammasome activation is critical for the induction of protective immunity, but molecular insights are still lacking. Here, the authors express NLRP3 variants targeted to different cellular lo...

0166

Reposted by Elvira Boršić Mlinarič

Waggoner Lab @labwaggoner.bsky.social · 10/02/2025

Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants www.nature.com/articles/s41... @natimmunol.bsky.social @sethlucianmasters.bsky.social

1234