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Shivcharan et al. report that endosomal damage sensing by the danger receptor galectin-8 licenses noncanonical inflammasome activation and pyroptosis during intracellular bacterial infections in human...

NLRP3 inflammasome activation is critical for the induction of protective immunity, but molecular insights are still lacking. Here, the authors express NLRP3 variants targeted to different cellular lo...

NLRP3 inflammasome activation is critical for the induction of protective immunity, but molecular insights are still lacking. Here, the authors express NLRP3 variants targeted to different cellular lo...

NLRP3 inflammasome activation is critical for the induction of protective immunity, but molecular insights are still lacking. Here, the authors express NLRP3 variants targeted to different cellular lo...

Boys and men are less likely to turn to their communities for social connection and support.

✨ Lighting Up a New Era in Cancer Treatment ✨   We are excited to introduce #SCALPEL – a #groundbreaking, Europe-wide initiative that is set to redefine…

Za odličnost njihovega raziskovanja bodo letos nagrajene molekularna biologinja Tajda Klobučar, raziskovalka na področju biomedicine Sara Orehek in kognitivna nevroznanstvenica Manca Peskar.

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‘Gasdermin-mediated pyroptosis can induce anti-tumor immune responses. Here the authors report a toolbox of gasdermin D variants for induction of pyroptosis, showing that, when combined with intratumo...

‘Gasdermin-mediated pyroptosis can induce anti-tumor immune responses. Here the authors report a toolbox of gasdermin D variants for induction of pyroptosis, showing that, when combined with intratumo...

Nature Immunology - Pyroptotic cell death results in inflammation. Here the authors find that F-actin-rich structures formed during macrophage pyroptosis persist after cell death to activate...

Pyroptotic cell death results in inflammation. Here the authors find that F-actin-rich structures formed during macrophage pyroptosis persist after cell death to activate dendritic cells.

PhD Project - CASE Project: Unravelling the role of extracellular vesicles in the orchestration of macrophage – mediated immune regulation. at University of York, listed on FindAPhD.com