iiinova — where your digital self keeps evolving

Reposted by Dr. Sunny Shin

Alison Criss @alisoncrissuva.bsky.social · 17/07/2026

UVA MIC representing at the Microbial Toxins and Pathogenicity GRC! Many thanks to @torreslab.bsky.social and @sunnyshinlab.bsky.social for an amazing meeting! @bradyspencer12.bsky.social

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Dr. Sunny Shin @sunnyshinlab.bsky.social · 17/07/2026

Amazing week of science & camaraderie at GRC Microbial Toxins & Pathogenicity! Many thanks to chair @torreslab.bsky.social & the discussion leaders, speakers, poster presenters, attendees, & staff for an awesome meeting! Excited to organize the next one with new vice-chair @sauerlab.bsky.social!

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Reposted by Dr. Sunny Shin

Valeria Reyes Ruiz @reyesruiz.bsky.social · 25/06/2026

Our lab is hiring an enthusiastic and motivated research specialist to study host-pathogen interactions in the context of S. aureus infection. For more information, see below: Lab website: www.reyesruizlab.org jobs.wisc.edu/jobs/researc...

jobs.wisc.edu

Research Specialist - Madison, Wisconsin, United States

Current Employees: If you are currently employed at any of the Universities of Wisconsin, log in to Workday to apply through the internal application process.Job Category:Academic StaffEmployment Type...

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Reposted by Dr. Sunny Shin

Rep. Jamie Raskin @raskin.house.gov · 25/06/2026

Public health research at world-class institutions like the NIH is an important public good. Rep. Suzan DelBene, Rep. Lori Trahan and I are leading 122 of our colleagues to oppose the Trump Administration’s efforts to give partisan political appointees final say over health research grants.

thebanner.com

Raskin moves to stop ‘disastrous’ threat against medical research

Rep. Jamie Raskin seeks to stop the Trump administration from putting political appointees in charge of federal health grants.

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elizabethginexi.bsky.social @elizabethginexi.bsky.social · 18/06/2026

For the past 18 months, the Trump administration’s approach to federal grants has followed a familiar pattern: announce a cancellation, face a lawsuit, sometimes lose. That is precisely what OMB’s proposed rewrite of 2 CFR Part 200 is designed to end. elizabethginexi.substack.com/p/the-omb-ru...

elizabethginexi.substack.com

The OMB Rule That Makes the Funding Cuts Legal

For the past eighteen months, the Trump administration’s approach to federal grants has followed a familiar pattern: announce a cancellation, face a lawsuit, sometimes lose.

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Reposted by Dr. Sunny Shin

Kranzusch Lab @kranzuschlab.bsky.social · 12/06/2026

How do human cells defend against viruses? @sgfern.bsky.social discovers that human immune proteins named ISGs target ancient features of replication shared between animal and bacterial viruses – opening analysis of human immunity to the power of bacterial genetics www.biorxiv.org/content/10.6...

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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 11/06/2026

Reminder — UW #Microbiology has an open search for an Assistant Professor, focusing on fundamental problems in #bacteriology! If you or someone you know would be suitable, here's the ad: apply.interfolio.com/185622

Screenshot of the job listing linked in full above

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Reposted by Dr. Sunny Shin

Heran Darwin, PhD @heran.bsky.social · 09/06/2026

New #ASM logo! @sunnyshinlab.bsky.social and Sarah Stanley!

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Reposted by Dr. Sunny Shin

Heran Darwin, PhD @heran.bsky.social · 07/06/2026

Closing it out! #asmmicrobe

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Heran Darwin, PhD @heran.bsky.social · 06/06/2026

Awesome to see my friends and colleagues at #microbe2026!

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Reposted by Dr. Sunny Shin

Stand Up for Science! @standupforscience.net · 31/05/2026

What does the new OMB proposal mean for science? How can we STOP VOUGHT and SAVE SCIENCE together? All of these questions and more to be discussed at the Emergency Science Meeting on June 2nd, 4PM ET, hosted by Stand Up for Science! Register at the link in our bio, or go here: zurl.co/g3vTZ

The graphic contains photos of speakers Prof. Timothy Snyder, U. of Toronto, Author of On Tyranny, Dr. Carolyn Bertozzi, Standford U. Nobel Laureate 2022, Amb. Norman Eisen, Democracy Defeders, and Dr. Elizabeth Ginexi, 20 yr NIH Veteren, "AND MORE..." to speak. The graphic reads: "TUESDAY JUNE 2nd 4PM ET/1PM PT, All welcome for the SUFS EMERGENCY SCIENCE MEETING, VIRTUAL AND ACCESSIBLE, What does the new OMB proposal mean for science? How can we STOP VOUGHT and SAVE SCIENCE together? REGISTER HERE: https://zurl.co/oCIDw, LINK IN BIO".

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Jeremy Berg @jeremymberg.bsky.social · 30/05/2026

Several people have asked for possible content and structure for comments regarding the proposed OMB regulations. With some suggestions from others, I have posted on example (as a Word document) for downloading). jeremymberg.github.io/jeremyberg.g... I hope this is helpful.

jeremymberg.github.io

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Liz Neeley @lizneeley.bsky.social · 29/05/2026

Each week, I write a briefing on what happened in US science & higher ed. 🧪 Needed to write Year 2, Week 22 a day early. It is grim. - new NSF grant delays - gut-churning policy proposals on NDA, accreditation, peer review - academic freedom surveys & so much more buttondown.com/liminalcreat...

buttondown.com

Year 2, Week 22

May 23-28, 2026 – by design

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Reposted by Dr. Sunny Shin

elizabethginexi.bsky.social @elizabethginexi.bsky.social · 29/05/2026

Summary of Key Changes in OMB’s Proposed Federal Financial Assistance Rule. Russell Vought is going destroy American Science. elizabethginexi.substack.com/p/summary-of...

elizabethginexi.substack.com

Summary of Key Changes in OMB’s Proposed Federal Financial Assistance Rule

Russell Vought is going destroy American Science

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Reposted by Dr. Sunny Shin

Johns Hopkins University @jhu.edu · 26/05/2026

NIH has allocated just 33% of its normal budget this year, putting critical medical breakthroughs at risk. Johns Hopkins President Ron Daniels and University of Kansas Chancellor Dr. Douglas Girod are calling on the government to release it before the damage becomes permanent. bit.ly/4f3GuzR

hub.jhu.edu

President Daniels in WSJ op-ed: Get the federal science money flowing

JHU president, University of Kansas chancellor urge federal agencies to release congressionally appropriated funds to fuel America's research engine

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Reposted by Dr. Sunny Shin

Denis Wirtz @deniswirtz.bsky.social · 21/05/2026

The NIH has been holding back grants from funds Congress has already approved. www.wsj.com/opinion/get-...

wsj.com

Opinion | Get the Federal Science Money Flowing

The NIH has been holding back grants from funds Congress has already approved.

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Reposted by Dr. Sunny Shin

elizabethginexi.bsky.social @elizabethginexi.bsky.social · 20/05/2026

Wondering why the NIH has such a slow pace of grantmaking this year? Here’s my breakdown. elizabethginexi.substack.com/p/the-execut...

elizabethginexi.substack.com

The Executive Orders Blocking Your NIH Grant

This image was generated by Google AI (Gemini)

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Reposted by Dr. Sunny Shin

ASM @asm.org · 29/04/2026

ASM's Mechanism Discovery Unit, focused on advancing research into the basic principles of microbial life, has launched! The unit is led by Glen McGugan, Ph.D., & Alison Criss, Ph.D., & guided by a Scientific Advisory Council of 14 experts. Read more: asm.org/press-releas...

ASM Mechanism Discovery Unit title with headshots of the Director and Chair.

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Reposted by Dr. Sunny Shin

Ivan Zanoni @lozanzi.bsky.social · 27/04/2026

More than thrilled to share that I’ve been promoted to full (tenured) Professor @harvardmed.bsky.social @harvard.edu! This only happened because of the hard work of many people, but I want to dedicate this promotion to my grandmas, Nonna Maria & Nonna Vevè. A #FirstGen thread 🧵 1/x

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Dr. Sunny Shin @sunnyshinlab.bsky.social · 12/03/2026

Deadline extended to March 27th for the CSHA conference on Bacterial Infection & Host Defense May 11-15, 2026! We have a fantastic list of speakers and opportunities for abstract talks. For full details, please visit the conference webpage: www.csh-asia.org?content/2975. Hope to see you in Suzhou!

Flyer for CSHA Conference on Bacterial Infection & Host Defense

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Reposted by Dr. Sunny Shin

Asaf Levy @asaflevylab.bsky.social · 10/03/2026

Ubercool. Toxin-antitoxin systems were discovered 40 years ago in E. coli, and later on in many genomes including in euks. Now the 1st TA system is reported in the mouse genome! It affects embryo killing. Amazing distribution of a simple yet efficient genetic system www.biorxiv.org/content/10.6...

biorxiv.org

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Reposted by Dr. Sunny Shin

Colin Conine @colinconine.bsky.social · 10/03/2026

Check out this collaboration between Kellie Jurado’s lab and mine. We find that paternal immune activation reprograms the epididymis and, subsequently, small RNAs in sperm, which modulate post-fertilization embryonic gene expression and immunity in offspring in a sex-specific manner.

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Reposted by Dr. Sunny Shin

Dr. Sunny Shin @sunnyshinlab.bsky.social · 28/02/2026

Please join us for the Cold Spring Harbor Asia @cshlnews.bsky.social meeting on Bacterial Infection & Host Defense this May 11-15 in Suzhou, China! We have a fantastic lineup of speakers. Abstract deadline is March 6. Hope to see you there!

Poster of the 2026 CSHA meeting on Bacterial Infection & Host Defense.

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Dr. Sunny Shin @sunnyshinlab.bsky.social · 28/02/2026

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Reposted by Dr. Sunny Shin

Waggoner Lab @labwaggoner.bsky.social · 04/02/2026

Phosphoinositide and cholesterol are endogenous ligands of STING in innate immune signaling @nature.com @upittpress.bsky.social @utswim.bsky.social www.nature.com/articles/s41... www.nature.com/articles/s41...

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Reposted by Dr. Sunny Shin

Colette Delawalla, PhD @cdelawalla.bsky.social · 29/01/2026

Ok people!!! I believe we may be taking March 7th NATIONAL! This will require financial support. Last year, nationwide, the protests cost $75,000. We need all the help we can get! Help us fuel the fight here: www.standupforscience.net/donate @standupforscience.bsky.social #standupforscience

standupforscience.net

Fuel the fight! — STAND UP FOR SCIENCE

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Reposted by Dr. Sunny Shin

Dr. Sunny Shin @sunnyshinlab.bsky.social · 27/01/2026

Congratulations to my postdoc @mikelhaggadone.bsky.social for receiving the @aai.org Ray Owen Poster Award at the Midwinter Conference of Immunologists @midwinter-immun.bsky.social for his work with Brian Goldspiel & @metabailism.bsky.social, which is now on bioRxiv! www.biorxiv.org/content/10.6...

Mikel Haggadone is holding the AAI Ray Owen Poster Award certificate from the Midwinter Conference of Immunologists

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Reposted by Dr. Sunny Shin

Mikel Haggadone, PhD @mikelhaggadone.bsky.social · 27/01/2026

I had a wonderful time at Midwinter Immunology & was honored to receive the Ray Owen Poster Award after an awesome presentation by @sunnyshinlab.bsky.social! 2026 was my first time attending — definitely won’t be my last! Thank you to @brodskyigorlab.bsky.social & co. for an amazing meeting! 🙏

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Dr. Sunny Shin @sunnyshinlab.bsky.social · 27/01/2026

Congratulations to my & @brodskyigorlab.bsky.social’s joint postdoc Suhas Bobba on receiving the @asm.org Infection & Immunity Poster Award for his work on innate immune control of intestinal Yersinia infection at the Midwinter Conference of Immunologists @midwinter-immun.bsky.social!

Suhas Bobba holding the ASM Infection and Immunity Poster Award certificate at the Midwinter Conference of Immunologists

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Dr. Sunny Shin @sunnyshinlab.bsky.social · 27/01/2026

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Reposted by Dr. Sunny Shin

Victor J. Torres @torreslab.bsky.social · 24/01/2026

Excited to announce the upcoming 2026 Microbial Toxins and Pathogenicity GRC and GRS meeting taking place July 12 - 17, 2026 at Waterville Valley in New Hampshire. This meeting will be chaired by yours truly and co-chaired by @sunnyshinlab.bsky.social www.grc.org/microbial-to...

grc.org

2026 Microbial Toxins and Pathogenicity Conference GRC

The 2026 Gordon Research Conference on Microbial Toxins and Pathogenicity will be held in Waterville Valley, New Hampshire. Apply today to reserve your spot.

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Reposted by Dr. Sunny Shin

Dr. Sunny Shin @sunnyshinlab.bsky.social · 21/01/2026

Thrilled to share our new preprint showing that dietary amino acids license the NLRP3 inflammasome via mTOR-dependent mRNA translation! Congrats to co-1st authors @mikelhaggadone.bsky.social, Brian Goldspiel, co-senior author @metabailism.bsky.social & collaborators! www.biorxiv.org/content/10.6...

biorxiv.org

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Reposted by Dr. Sunny Shin

Will Bailis @metabailism.bsky.social · 22/01/2026

Excited to share our new pre-print on the control of NLRP3 inflammasome assembly and ASC translation dynamics by environmental amino acids. A true team science effort: our phenomenal partners @mikelhaggadone.bsky.social & @sunnyshinlab.bsky.social working with Brian Goldspiel 🙏

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Waggoner Lab @labwaggoner.bsky.social · 22/01/2026

@biorxivpreprint.bsky.social Environmental Amino Acid Sensing Regulates the Rate of ASC Translation and NLRP3 Inflammasome Assembly @briangoldspiel.bsky.social @mikelhaggadone.bsky.social @sunnyshinlab.bsky.social @pennmicro.bsky.social @metabailism.bsky.social www.biorxiv.org/content/10.6...

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Reposted by Dr. Sunny Shin

Igor Brodsky @brodskyigorlab.bsky.social · 22/01/2026

Congrats @sunnyshinlab.bsky.social and colleagues on this super cool and intriguing story on the role of dietary amino acids in regulating NLRP3 inflammasome activation by controlling translation of the ASC adapter! 🤯🙌🏼

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Mikel Haggadone, PhD @mikelhaggadone.bsky.social · 21/01/2026

I’m stoked to share my postdoc work with @sunnyshinlab.bsky.social, a collaborative effort with @metabailism.bsky.social & Brian Goldspiel, aided by many valued collaborators: Environmental Amino Acid Sensing Regulates the Rate of ASC Translation and NLRP3 Inflammasome Assembly. Some big takeaways:

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Dr. Sunny Shin @sunnyshinlab.bsky.social · 21/01/2026

biorxiv.org

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Zhenyu Zhong @zhenyuzhong.bsky.social · 16/01/2026

Why is obesity often associated with dysregulated, low-grade chronic inflammation? In our new paper in @science.org we show that obesity rewires nucleotide metabolism in immune cells, making inflammatory responses much easier to trigger. www.science.org/doi/10.1126/...

science.org

Nucleotide metabolic rewiring enables NLRP3 inflammasome hyperactivation in obesity

Obesity is a major disease risk factor due to obesity-associated hyperinflammation. We found that obesity induced Nod-like receptor pyrin domain–containing 3 (NLRP3) inflammasome hyperactivation and e...

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Reposted by Dr. Sunny Shin

Andreas Bäumler @abaumler.bsky.social · 23/12/2025

Friday we lost a brilliant mind, colleague, and friend to her battle with pancreatic cancer. Those who knew her will remember Helene Andrews-Polymenis for her warmth, generosity and leadership. She will be missed by many. RIP

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Heran Darwin, PhD @heran.bsky.social · 22/12/2025

While everyone is hustling for the holidays, hopefully folks will have time to submit abstracts or register for #ASMMicrobe2026 in DC! Please repost!

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Reposted by Dr. Sunny Shin

Mia Levine @levine-lab.bsky.social · 28/11/2025

How to keep in step when your (protein) partner speeds up… Here we investigated the adaptive remodeling of a protein-protein interaction surface essential for telomere protection. Congrats to whole team! www.science.org/doi/10.1126/...

science.org

Rapid compensatory evolution within a multiprotein complex preserves telomere integrity

Intragenomic conflict with selfish genetic elements spurs adaptive changes in subunits of essential multiprotein complexes. Whether and how these adaptive changes disrupt interactions within such comp...

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Reposted by Dr. Sunny Shin

Mark Histed @markhisted.org · 13/11/2025

A bad thing is unfolding at NIH this week: It looks like the Trump administration is trying to replace key civil servant scientific leaders, the Institute Directors, with political hires. These directors control the NIH budget, tens of billions. A bit of a video explainer here: 1/ 🧪

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Ivan Zanoni @lozanzi.bsky.social · 31/10/2025

#InflammasomePower! 💥New paper alert💥 How is NLPR3 primed & activated in chronic non-communicable inflammatory diseases? With @oceanedufies.bsky.social &co we show that chronic exposure to oxPAPC drives NRF2 activation that primes & activates NLRP3 sustaining #atherosclerosis in mice & humans! 👇👇👇

biorxiv.org

Chronic sensing of host-derived lipids is an all-in-one signal that primes and activates NLRP3.

Activation of the NLRP3 inflammasome leads to the production of bioactive interleukin (IL)-1β fostering atherosclerosis. The current dogma is that NLRP3 must be first primed by microbial stimuli, know...

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Reposted by Dr. Sunny Shin

Deepta Bhattacharya @deeptabhattacha.bsky.social · 30/10/2025

The UofA is hiring for a Principal Scientist in cancer immunology! This isn’t a typical academic position—we're looking for a scientist with a great idea but needs time/resources to translate and commercialize. Please repost and apply if interested! arizona.csod.com/ux/ats/caree...

arizona.csod.com

Principal Scientist, Center for Advanced Molecular and Immunological Therapies

Develop a research program in the advancement of immunological therapies.Play a crucial role in all aspects of research development, implementation, a...

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Reposted by Dr. Sunny Shin

Stephen Tang @stephentang23.bsky.social · 17/10/2025

Genome maintenance by telomerase is a fundamental process in nearly all eukaryotes. But where does it come from? Today, we report the discovery of telomerase homologs in a family of antiviral reverse transcriptases, revealing an unexpected evolutionary origin in bacteria. doi.org/10.1101/2025...

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