Sign in

Izabela Sumara

@sumaralab.bsky.social
400 followers 484 following 23 posts

Cell cycle, mitosis, nuclear pores, ubiquitin, disease. Group leader @igbmc.bsky.social, research director DR1 @cnrs.fr, Strasbourg, France. Alumna @JagiellonskiUni.bsky.social @impvienna.bsky.social @ethz.ch Hobby cook and occasional runner.

PostsRepliesMedia
Izabela Sumara @sumaralab.bsky.social · 22/09/2026
Very proud of our new publication in EMBO Molecular Medicine 🥳, where we describe an antimitotic that selectively inhibits tumor growth without affecting normal tissues. Big congratulations to Eva Pangou, Sushil Awal, Ksenia Krupina and all authors, and many thanks to our amazing collaborators! 🔬🥳
link.springer.com
Pharmacological inhibition of UBASH3B induces mitotic arrest and selectively reduces tumor growth - EMBO Molecular Medicine
Cancer cells tolerate mitotic errors to sustain proliferation, yet the molecular dependencies enabling this tolerance remain poorly understood and largely unexploited therapeutically. UBASH3B ensures ...
141
Izabela Sumara @sumaralab.bsky.social · 08/09/2026
I’m very happy to share a press release about our recent publication on how annulate lamellae build new nuclear pores. 🔬🥳 Grateful to @cnrs.fr for highlighting our work and helping share these findings! 🙏✨
001
Izabela Sumara @sumaralab.bsky.social · 30/03/2026
Our new study is out! 🎉🚀 Annulate lamellae aren’t just static reservoirs, they dynamically supply pre-assembled nuclear pores to the nucleus (~1/3 of new NPCs) in normal somatic cells. A new pathway for nuclear pore assembly supporting nuclear expansion.
nature.com
RanBP2-dependent annulate lamellae drive nuclear pore assembly and nuclear expansion - Nature Communications
Whether annulate lamellae (AL) occur in normal somatic cells was an open question. Here, the authors demonstrate that AL drive nuclear pore complex assembly and nuclear expansion during G1, defining a...
063
Izabela Sumara @sumaralab.bsky.social · 03/02/2026
We are extremely happy to welcome Xiao Lyu to our team! She will pursue her PhD focusing on cancer-specific vulnerabilities. We wish you every success, Xiao! 🤞💪😄
030
Izabela Sumara @sumaralab.bsky.social · 15/01/2026
We had a little champagne and some delicious cakes to celebrate the acceptance of our new paper 🤩 We also killed a snowman…🫣😉
140
Izabela Sumara @sumaralab.bsky.social · 07/01/2026
I have the great pleasure of hosting Dirk Görlich at the IGBMC this Friday, and I very much look forward to the stimulating and insightful discussions.
001
Izabela Sumara @sumaralab.bsky.social · 03/12/2025
Secret Santa paid a visit to the Sumara Lab today! 🌟🎅🎄
050
Izabela Sumara @sumaralab.bsky.social · 27/11/2025
We are excited to share the revised version of our preprint elucidating the role of Annulate Lamellae in the assembly of Nuclear Pore Complexes #NPCs during early interphase. Big thanks to Junyan Lin and all collaborators for their fantastic work! 🙏🎉
biorxiv.org
RanBP2-dependent annulate lamellae drive nuclear pore assembly and nuclear expansion
Nuclear pore complexes (NPCs) enable nucleocytoplasmic transport. While NPCs primarily localize to the nuclear envelope (NE), they also appear in cytoplasmic endoplasmic reticulum (ER) membranes calle...
0123
Izabela Sumara @sumaralab.bsky.social · 21/11/2025
Our own Dr. Xiaotian Liu presented a talk on the role of asymmetric dimethylation in nuclear pore assembly at the #EESNucleus EMBO meeting. We couldn’t be prouder 🤓😎😁😁
081
Izabela Sumara @sumaralab.bsky.social · 21/11/2025
It was a fantastic #EESNucleus meeting! Thank you so much to the organizers and the entire supporting team 🙏😁
021
Reposted by Izabela Sumara
Christian Schlieker @schliekerlab.bsky.social · 07/11/2025
This was indeed a fantastic trip, thanks so much for hosting me! I very much enjoyed learning about fantastic science from you and your amazing @sumatalab.bsky.social team and the great IGBMC community!
021
Izabela Sumara @sumaralab.bsky.social · 07/11/2025
A new photo of my amazing team! 🤩🌟🥰
050
Izabela Sumara @sumaralab.bsky.social · 07/11/2025
I had the great pleasure of hosting Christian Schlieker @schliekerlab.bsky.social for a seminar at IGBMC @igbmc.bsky.social Thank you 🙏, Christian, for sharing your inspiring science and ideas, and for such engaging discussions with PIs and my team. A truly wonderful visit! 🤩😁
050
Izabela Sumara @sumaralab.bsky.social · 30/10/2025
Minimal CDK and maximal Damien Coudreuse lab! Big congrats 🎉🎈🍾
020
Izabela Sumara @sumaralab.bsky.social · 01/10/2025
Today we welcomed our new postdoc, Dr. Marintia Nava @marintianava.bsky.social, to the lab! We’re so happy to have her on board and wish her the best of luck as she begins her exciting work on Annulate Lamellae. Welcome, Marintia! 😁🤩🌟
0101
Reposted by Izabela Sumara
Journal of Cell Biology @jcb.org · 26/09/2025
Liao et al. @sumaralab.bsky.social show that UBAP2L ensures homeostasis of nuclear pore complexes at the intact nuclear envelope. rupress.org/jcb/article/... 📕 In our Intermediate Filaments collection: rupress.org/jcb/collecti...
053
Reposted by Izabela Sumara
luskinglab.bsky.social @luskinglab.bsky.social · 31/08/2025
Last day to submit abstracts! Nuclear cell biologists, mechanobiologists, et al. don’t miss out - amazing interdisciplinary line up: computational biology, biophysics, development, genomics - we will have it all!
062
Reposted by Izabela Sumara
Yale Cell Biology @yalecellbiology.bsky.social · 19/09/2025
Did you know that all nuclear pore complexes (NPCs) are not the same? @luskinglab.bsky.social propose a new hypothesis for how nuclear mechanics may impact the compositional plasticity of NPCs with implications for tissue-specific diseases caused by NPC dysfunction. www.nature.com/articles/s41...
nature.com
Nuclear mechanics as a determinant of nuclear pore complex plasticity - Nature Cell Biology
In this Review, Lusk et al. discuss emerging insights into nuclear pore complex variability with regard to composition and dilation state, and propose nuclear mechanics as a key determinant of driving...
0177
Reposted by Izabela Sumara
Albert and Mary Lasker Foundation @laskerfdn.bsky.social · 12/09/2025
Why are low-complexity domains (LCDs) in proteins important? #LaskerAward winners Dirk Görlich & Steven McKnight showed that they are critical for intracellular transport and organization. #Lasker2025 #structuralbiology #phaseseparation @mpi-nat.bsky.social
youtube.com
Low-complexity domains: structures & functions
The 2025 Albert Lasker Basic Medical Research Award honors Dirk Görlich and Steven McKnight for discoveries that exposed the structures and functions of low-complexity domains within protein…
033
Izabela Sumara @sumaralab.bsky.social · 10/09/2025
We are very happy and proud to celebrate our freshly minted Dr. Xiaotian Liu! 🎉🥂🥳 Many thanks 🙏 to the jury members Ali Hamiche, Lionel Pintard @ccdlab.bsky.social and Charlène Boumendil @charleneboumendil.bsky.social, who also gave a wonderful seminar at the @igbmc.bsky.social
120
Reposted by Izabela Sumara
Journal of Cell Science @jcellsci.bsky.social · 28/08/2025
Call for papers: Cell Biology of the Nucleus We invite you to submit your latest research to our special issue: Cell Biology of the Nucleus, guest edited by @abbybuch.bsky.social alongside JCS Editor Megan King @luskinglab.bsky.social. Deadline: 3 November journals.biologists.com/jcs/pages/nu...
Call for papers for JCS Special Issue
Text: Special Issue
Cell Biology of the Nucleus
Guest Editor: Abby Buchwalter
Deadline: 3 November 2025
Image of a cell with a heart-shaped nucleus (Image credit: Hoang Anh Le)
Journal of Cell Science logo
02114
Reposted by Izabela Sumara
Clausen Lab @clausenlab.bsky.social · 24/06/2025
postdoc opening in vienna: study lipid droplets (LDs) with integrative structural biology, uncover how LD proteins shuttle between cytosol & nucleus to regulate lipid metabolism, organelle architecture and immune response. #VIP3 #lipidtime #cryoEM #coffee training.vbc.ac.at/post-docs/vi...
training.vbc.ac.at
VIP³ Post Doc Program (2025 - 2030)
VIP3 is a postdoctoral fellowship program at the Vienna BioCenter offering three – year fellowships that are open to candidates with backgrounds in life sciences, chemistry, physics, medicine, enginee...
01111
Reposted by Izabela Sumara
Journal of Cell Biology @jcb.org · 12/06/2025
New study showing the development of pan-Expansion Microscopy by Morgan et al. @luskinglab.bsky.social to reveal the molecular composition and structural plasticity of individual nuclear pore complexes including LINC complex-dependent dilation. rupress.org/jcb/article/...
03010
Reposted by Izabela Sumara
Yasin Dagdas @plantophagy.bsky.social · 02/06/2025
Important changes on @erc.europa.eu grants‼️Grant structure & most importantly eligibility timeframes (10 years for starting, 15 years for consolidator post PhD-but you can have them only once) changes: erc.europa.eu/news-events/...
erc.europa.eu
Changes to the 2026 and 2027 Work Programmes
With the launch of the competitions for grants under ERC Work Programme 2026 in July of this year, several changes to the submission of applications and the evaluation of proposals will apply. The mai...
04930
Reposted by Izabela Sumara
EMBO @embo.org · 27/05/2025
Mark your calendars! The next ASCB | EMBO Meeting #CellBio2025 is taking place in Philadelphia, US, 6–10 December 2025: www.ascb.org/cellbio2025/ 🧪 @ascbiology.bsky.social‬ #CellBiology #research
034
Reposted by Izabela Sumara
Dr. Peter Walentek (Walentek Lab) @walenteklab.bsky.social · 27/05/2025
We are hiring #postdocs and #phd students in the areas of #devbio #cellbio #Bioinformatics #mathematics #modeling. This is the full add with details: euraxess.de/jobs/346670 This our lab homepage: www.uniklinik-freiburg.de/walentek-en....
euraxess.de
Multiple Postdoc and PhD positions in developmental biology, genetics, bioinformatics and mathematical modeling - Walentek Lab - Freiburg, Germany
University Freiburg Medical Center is a leading institution in biomedical research in the heart of Europe with close associations to other institutions and centers in the tri-national Eucor area (Germ...
01218
Reposted by Izabela Sumara
MIT Koch Institute @mitkochinstitute.bsky.social · 22/05/2025
Are you a grad student pursuing the life sciences or biomedical research outside the U.S.? Applications now open for the Angelika Amon Young Scientist Award until June 13. Enter to win $1,000 USD & a chance to present your work & network w/ MIT faculty. buff.ly/F7s94vW
Angelika Amon in her laboratory.
0910
Reposted by Izabela Sumara
dfachinetti.bsky.social @dfachinetti.bsky.social · 21/05/2025
Hi all, my team institut-curie.org/team/fachine... @institutcurie.bsky.social is looking for a Bioinformatician. You can find more details about the position here: euraxess.ec.europa.eu/jobs/344508 Is anyone looking for a job in the lovely Paris?
01314
Izabela Sumara @sumaralab.bsky.social · 12/05/2025
Extremely excited and happy to welcome a new postdoc Dr Mathieu Meode to the Sumara lab 🤩! We wish him all the best of luck🤞studying biogenesis of #nuclear pores in health and disease 🤓
121
Reposted by Izabela Sumara
Hauf Lab @silkehauflab.bsky.social · 07/05/2025
⏳Only 20 days left to register for #CellCycle2025! June 23–26 at @salkinstitute.bsky.social The US may not be everyone's top travel pick right now—but if you can come, please do. Great science, and a reminder that research is fun and thrives on global collaboration. www.salk.edu/cellcycle2025
Salk Cell Cycle Meeting Poster. Meeting date June 23 - 26. Abstract deadline May 27. Registration deadline June 9. More info www.salk.edu/cellcycle2025
087
Reposted by Izabela Sumara
Maria Sibilia @maria-sibilia.bsky.social · 06/05/2025
Check out our new paper! We identified Smoc2 as an interesting target that is upregulated upon EGFR deletion, driving stemness signatures, reduction in cell size and metabolic rewiring. 💪 🔝👍
061
Reposted by Izabela Sumara
Gaia Pigino @gaiapigino.bsky.social · 19/02/2025
“Join the Pigino Lab! We’re hiring a PhD student to explore primary cilia biology using advanced imaging, spatial ‘omics, and AI. Apply now at www.cilia-ai.eu and be part of the Cilia-AI Doctoral Network!”
02827
Reposted by Izabela Sumara
Ana Pombo @apombo1.bsky.social · 09/03/2025
Join us for the 2025 GRC Genome Architecture www.grc.org/genome-archi... @spp2202.bsky.social @jobdekker.bsky.social @metorrespadilla.bsky.social @jopkind.bsky.social @dimplenotani.bsky.social @stanleyqilab.bsky.social @andybelmont.bsky.social @fondufemittendorf.bsky.social @boyanbonev.bsky.social
03112
Reposted by Izabela Sumara
Carlos Conde @carlos-conde.bsky.social · 13/04/2025
I'm happy to share our study “Proximity-based activation of AURORA A by MPS1 potentiates error correction” now published at @currentbiology.bsky.social www.sciencedirect.com/science/arti... It describes a new way kinetochores and centrosomes communicate to ensure accurate chromosome segregation.
sciencedirect.com
Proximity-based activation of AURORA A by MPS1 potentiates error correction
Faithful cell division relies on mitotic chromosomes becoming bioriented with each pair of sister kinetochores bound to microtubules oriented toward o…
12711
Reposted by Izabela Sumara
Barbara Marte @barbmarte.bsky.social · 01/05/2025
new out in Nature www.nature.com/articles/s41...
nature.com
Cell cycle duration determines oncogenic transformation capacity - Nature
Total cell cycle duration is a key hallmark of cancer initiation, and determines whether defects in apoptosis, senescence, immune surveillance, angiogenesis, DNA repair, polarity and proliferation lea...
0186
Reposted by Izabela Sumara
Maria GóRNA @mgorna.bsky.social · 20/02/2025
We're looking for a *PhD student* to join the FunHitDisco project! 😍 We offer work in a European consortium (SE/PL/NL/IT) dedicated to antifungal drug discovery! 🧫 💊 If you love proteins and structural biology, come join us! 🤗 #hiring #PhDoffer #PhDjob #PhDstudentship gorna.uw.edu.pl/en/jobs
153
Reposted by Izabela Sumara
Manuel Mendoza @longchrom.bsky.social · 30/04/2025
US colleagues: Looking to launch or move your lab to France? The ARC Foundation is recruiting outstanding US-based scientists to lead research in oncology. Generous support & relocation help included. Details here: www.fondation-arc.org/projets/recr... Interested? Contact us!
fondation-arc.org
Recruiting international leaders in oncology from USA 2025
By offering a significant support, the call for proposal "Recruiting international leaders in Oncology from USA" wishes to allow the implantation in France of new scientific leader that will establish...
055
Reposted by Izabela Sumara
Kat Toropova @kattoropova.bsky.social · 30/04/2025
Postdoc position in my lab: investigating how the microtubule motor protein dynein-2 works in cilia. Here's dynein-2 at work translocating microtubules - how is this activity regulated? How does dynein-2 malfunction in disease? Find out more and apply: my.corehr.com/pls/uoxrecru...
26434
Reposted by Izabela Sumara
EMBO @embo.org · 30/04/2025
The FEBS | EMBO Women in Science Award aims to highlight the major contributions made by female scientists to #LifeSciences research. Winners of the award are inspiring role models for future generations of #WomenInScience Nominate a scientist by 15 May: www.embo.org/the-embo-com... 🧪
embo.org
FEBS|EMBO Women in Science Awardees – Nominate for the Women in Science Award – EMBO
Nominees should be female scientists working in an EMBC Member State or FEBS member country, who have made outstanding contributions to life sciences research and significantly advanced our…
13424
Reposted by Izabela Sumara
Christian Frezza @frezzalab.bsky.social · 20/04/2025
Good Sunday, all, and happy Easter to those who celebrate it. Here is a marvellous collection of papers in #cancermetabolism and #mitochondrialbiology, ready for you! biomed.news/bims-camemi/... @biomednews.bsky.social "There can be no centre in infinity."-Lucretius
media.tenor.com
a purple and yellow easter egg with polka dots and a zig zag pattern
ALT: a purple and yellow easter egg with polka dots and a zig zag pattern
02312
Reposted by Izabela Sumara
Kohler Proteostasis Lab @vkohler-lab.bsky.social · 18/04/2025
We’re happy to share our #PostdoctoralFellowship in the #KohlerProteostasisLab. As an inclusive team, we’re excited to learn from the new expertise you bring- in turn we’re committed to your #CareerDevelopment through tailored mentorship, leadership and science‑communication training. #WeAreHiring
014
Reposted by Izabela Sumara
stapleslab.bsky.social @stapleslab.bsky.social · 12/03/2025
Please repost! Post-doc studying novel mechanisms of post-replicative gap-filling available in my lab here in beautiful Snowdonia, between July 2025 to end Nov 2026. Generous travel budget. Lab is full of friendly and supportive colleagues. Link below, or DM me/email c.staples@bangor.ac.uk for info
1715
Reposted by Izabela Sumara
Philip Gunkel @philipgunkel.bsky.social · 28/01/2025
Registration is open for a great meeting in Potsdam, Germany (July 23-27) ... for everyone interested in the biology of the nuclear envelope and related topics (events.gwdg.de/event/1012/)
033
Izabela Sumara @sumaralab.bsky.social · 15/04/2025
That was fast… 😉 Big congrats! 🍾🎈👏
120
Reposted by Izabela Sumara
Andrea Musacchio @andrea-musacchio.bsky.social · 12/02/2025
Cell division aficionados: please spread out and consider registering to this conference!
02413
Izabela Sumara @sumaralab.bsky.social · 14/04/2025
OMG, they do! Big congrats 🍾🎈🎊
110
Izabela Sumara @sumaralab.bsky.social · 14/04/2025
Sumara lab is on Bluesky! 🎉😁😎🦋
0191