The EMBO Journal - Cell division involves the complete reorganization of the cellular architecture, requiring precise coordination of cellular processes in space and time, but how does this control...

Activation of PLK1, a master mitotic kinase, requires phosphorylation of its activation segment on Thr210, within a basic consensus sequence for Aurora kinases. Aurora B-dependent phosphorylation of T...

The evolutionarily conserved, intrinsically disordered protein Bora is critical for initiating the activation of mitotic kinases. Once phosphorylated at Ser112 by Cyclin A-Cdk1 kinase, phospho-Bora ac...

This video is the culmination of several years attempting to: (1) Figure out best practices for modeling protein-protein interactions; (2) Understand the This video is the culmination of several years...

Taniguchi et al. structurally analyse nuclear pore complex architecture in situ during differentiation, which is associated with mechanical constraints on the nuclear envelope. They link nuclear pore ...

The neuronal microtubule cytoskeleton is highly polarized, with most microtubules growing away from the soma in axons (plus-end-out), but many microtu…

imageimageGreatwall, a conserved MAST-like kinase with crucial mitotic entry functions, is curiously absent in worms. Here, the single canonical MAST kinase family member KIN-4 is shown to fulfill thi...

This manuscript reports on the use of the endogenous fluorescence of green, orange, and red fluorescent proteins directly in gels after separation by SDS-PAGE. This protocol bypasses the need for mem....

Les tissus épithéliaux, présents partout dans le corps humain, sont en interaction constante avec leur environnement.