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Stig Ove Bøe

@stigoveboe.bsky.social
93 followers 122 following 8 posts

Epithelial Mechanics, Active Matter, Biology and Physics

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Victor Yashunsky @yashunsky.bsky.social · 06/09/2026
Our @natphys.nature.com paper is now out! We find that defect creation & annihilation in bacteria and cells collectives spontaneously break mirror symmetry—unpredicted by active nematic theory. #softmatter #chiral #ActiveMatter #TopologicalDefects #LivingMatter #CellPolarity rdcu.be/yWTRbT26p9qa
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Benoit Ladoux @bladoux.bsky.social · 02/09/2026
Happy to share our new preprint! We uncover how local force imbalances drive keratinocyte delamination and upward motion, while neighboring cells close the basal layer below. Amazing work from @andreasschoenit.bsky.social! www.biorxiv.org/content/10.6...
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Xavier Trepat @xaviertrepat.bsky.social · 06/08/2026
When tension increases, the nucleus escapes. New paper out in @natphys.nature.com. Check out Tom's thread for a summary 👇
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FocalPlane @focalplane.bsky.social · 27/07/2026
ICYMI: Our preprint list covering the latest research in bioimage analysis is now up on FocalPlane. Let us know if you have any recommendations! focalplane.biologists.com/2026/07/24/m...
focalplane.biologists.com
Microscopy preprints: bioimage analysis - FocalPlane
Microscopy preprints: bioimage analysis - News
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Zebrafish Rock! @zebrafishrock.bsky.social · 05/07/2026
Rhythmic beating of a transgenic zebrafish embryo’s heart. Credit to @helenevignes.bsky.social, @cvagenapantoula.bsky.social & @vermotlab.bsky.social. #ZebrafishZunday 🧪
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Benoit Ladoux @bladoux.bsky.social · 03/07/2026
www.nature.com/articles/s41...
nature.com
Boundary geometry controls a topological defect transition that determines lumen nucleation in embryonic development - Nature Materials
The geometry of confining boundaries is shown to control three-dimensional topological defect configurations that precede formation of the central lumen in the developing mouse embryo, a key process i...
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allen institute @alleninstitute.org · 26/06/2026
New in @natmethods.nature.com: a new human stem cell model of EMT lets us watch cells transition in both 2D and 3D and shows human stem cells can undergo the transition differently depending on how they are grown. 🔗 doi.org/10.1038/s41592-026-03096-9
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Sasha | Kai Dao 🔬 @kaidaoscience.bsky.social · 19/06/2026
8 hours. That’s all fish need to heal wounds 🐟⏱️ Why are they so fast compared to humans? I break down the science of rapid regeneration in a microscopy story 🔬 Watch here: youtu.be/Mt9f61adaP0 #FluorescenceFriday #Microscopy
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Lei.ZHU @leizhu.bsky.social · 05/06/2026
🚀 KiloHz two photon live imaging #MultiphotonMicroscopy @laboptbio.bsky.social Two-photon light-sheet live imaging at kilohertz frame rate using birefringence-based pulse splitting #LightSheetMicroscopy #Bioimaging #Photonics #Microscopy #Zebrafish Article is available here: doi.org/10.1364/OPTI...
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Reese Richardson @reeserichardson.bsky.social · 05/06/2026
The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below)
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Stig Ove Bøe @stigoveboe.bsky.social · 29/05/2026
We present a new mechanism for triggering the flocking transition in epithelia, involving extensile polar defects and domain walls. Very happy to share this work, done in great collaboration with the @luizaangheluta.bsky.social group. preprint: arxiv.org/abs/2605.23339
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Torsten Wittmann @handle.invalid · 22/05/2026
A day in the life of a growing hiPSC spheroid expressing endogenously mStayGold-tagged histone 3.3 for #FluorescenceFriday and the #Snouty aficionados. 28 hours (and >50,000 exposures) later and they are still going! Home-brewed volume projection.
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Benoit Ladoux @bladoux.bsky.social · 29/04/2026
Happy to share our new paper on collective cell dynamics. Great work from Yuan Shen @ijmonod.bsky.social ! Dynamic heterogeneity and hidden fluidity in dense epithelial tissues | Science Advances www.science.org/doi/10.1126/...
science.org
Dynamic heterogeneity and hidden fluidity in dense epithelial tissues
Densely packed epithelial tissues appear mechanically arrested at tissue scale, but their cells move in subtle, coordinated ways.
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Turlier lab @turlierlab.bsky.social · 12/04/2026
How can we learn tissue mechanics directly from cell patterns and images? In our new preprint, we introduce VertAX, a differentiable vertex-model framework in JAX for simulating epithelia, inferring parameters, and designing target tissue behaviors. shorturl.at/PUzT0 1/5
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Dr. Emma Lång @emmalaang.bsky.social · 28/01/2026
Searching for a new job? We’re hiring a Postdoctoral Fellow for an exciting new research project on Hidradenitis Suppurativa. Apply now and please pass this on to anyone who might be interested! www.finn.no/job/ad/44835...
finn.no
Postdoctoral Fellowship on Tissue mechanics and inflammatory processes in human skin | FINN.no
Project titleNavigating the Tunnel: Keratinocyte Dynamics & Therapeutic Targeting of IL-17 in Hidradenitis Suppurativa Position summaryWe seek a motivated
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Brugues Lab @brugueslab.bsky.social · 28/01/2026
Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧵 www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de
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Stig Ove Bøe @stigoveboe.bsky.social · 29/12/2025
Our review article is now available in Annual Review of Condensed Matter Physics: “Full-Integer Topological Defects in Polar Active Matter.” @luizaangheluta.bsky.social @emmalaang.bsky.social doi.org/10.1146/annu...
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Pau Guillamat @pauguillamat.bsky.social · 12/11/2025
Microfluidic pumping with active nematics! Self-organized and self-sustained. No external pumps. @pnas.org @ub.edu www.pnas.org/doi/10.1073/... #ActiveMatter #Microfluidics #SoftMatter
pnas.org
Active nematic pumps | PNAS
Microfluidics involves the manipulation of flows at the microscale, typically requiring external power sources to generate pressure gradients. Alte...
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Xavier Trepat @xaviertrepat.bsky.social · 01/09/2025
New preprint! 🚨 We uncover a slow adaptation to stretch that links star-bundling of keratin filaments with nuclear escape from its keratin cage. Led by @tomgolde.bsky.social‬ 🙌 @IBECBarcelona www.biorxiv.org/content/10.1...
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epithelial mechanics fan club @epimechfc.bsky.social · 23/08/2025
Collective cell motion has many forms, but rotation is the coolest of them all. I'm @onenimesa.bsky.social , and in this short🧵, I'll highlight some instances of global tissue rotation like this one from @BauschLab
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Irene Miguel-Aliaga @irenemiguel-aliaga.bsky.social · 19/03/2025
Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...
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Pau Guillamat @pauguillamat.bsky.social · 30/06/2025
New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations. The tissue morphogenesis logic, now engineered into living, programmable materials. www.biorxiv.org/content/10.1... #ActiveMatter #TissueEngineering
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Maik Bischoff @maikbischoff.bsky.social · 18/06/2025
FINALLY out in #Science Advances! 🎉 3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author! It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀 www.science.org/doi/10.1126/... #DevBio #CellBio #Microscopy
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epithelial mechanics fan club @epimechfc.bsky.social · 08/06/2025
What do we see when looking at cells under the microscope? 👉Some are bigger than others, some are elongated and align with the neighbors & others seem to move. Cool, right? But wouldn't it be cooler to quantify these observations? I'm @juliaeckert.bsky.social. Let's explore some analysis software!‬
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Zebrafish Rock! @zebrafishrock.bsky.social · 01/06/2025
Development of a transgenic zebrafish embryo. Credit to Dr. Mario Mendieta-Serrano. #ZebrafishZunday 🧪
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Amy Engevik @amyengevik.bsky.social · 24/05/2025
Happy #FluorescenceFriday!
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Arthur Michaut 🔬🐣 @amichaut.bsky.social · 12/05/2025
The tip of the cantilever consists of a fluorescent bead that contacts the epiblast. Because we know the force necessary to bend the cantilever, we can perform mechanical assays by driving the bead across the embryo and measure in real time the force applied to the tissue.
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Arthur Michaut 🔬🐣 @amichaut.bsky.social · 12/05/2025
🚨📣 New preprint alert! Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos! A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social 📄 www.biorxiv.org/content/10.1... #devbio #mechanics
biorxiv.org
Direct measurements of active forces and material properties unveil the active mechanics of early embryogenesis
Despite progress in probing tissue mechanics, direct long-term measurements in live embryonic epithelia are lacking. This limits our understanding of amniote embryonic morphogenesis, which takes place...
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epithelial mechanics fan club @epimechfc.bsky.social · 11/05/2025
Collective cell migration is fascinating! Some tissues behave like fluids (motile), others like solids (jammed). Check out some papers exploring this topic in this thread.
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Michalis Averof @michalis-averof.bsky.social · 10/05/2025
Trichoplax adhaerens is one of the simplest and most enigmatic animals on earth. Its body shows incredible fluidity, changing shape within minutes. In a recent visit by Andrea Pasini we had the chance to host and observe these amazing animals live. [movie accelerated 3x; animal 0.5 to 1 mm in size]
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epithelial mechanics fan club @epimechfc.bsky.social · 08/05/2025
B. Aigouy et al., Cell flow reorients the axis of planar polarity in the wing epithelium of Drosophila. Cell (2010). #EpithelialMechanics buff.ly/vH41dfH
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Erwin Frey @physicsoflifelmu.bsky.social · 06/05/2025
New in Nature Physics! In a great collaboration with @junlab.bsky.social and my students Henrik Weyer & @lwuerthner.bsky.social, we show how Min proteins in E. coli self-organize into robust, efficient patterns ensuring accurate cell division across conditions. 📄 www.nature.com/articles/s41...
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Marine Biological Laboratory @mblscience.bsky.social · 05/05/2025
It's #MicroscopyMonday, so let's take a peek into the 🔬 This movie was taken by Shinya Inuoe, who built the polarizing microscope that allowed scientists to see mitotic spindle fibers live for the first time. Dr. Inuoe premiered his research at MBL.
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Elisa Nerli @nerlielisa.bsky.social · 09/04/2025
How can organs regenerate fast? Bioelectricity helps -- by coupling sub-second electrical injury signals to regenerative proliferation. First preprint from my potsdoc :D with @liujinghui.bsky.social @ritamateus.bsky.social @mpi-cbg.de and collaborators @mpipks.bsky.social @csbdresden.bsky.social
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Benoit Ladoux @bladoux.bsky.social · 19/04/2025
Flocking and active solid behavior of epithelial cells in our new study in @pnas.org Great work of Y. Shen, J. O'Byrne and @andreasschoenit.bsky.social and collaboration with A. Maitra and R. Voituriez! | PNAS www.pnas.org/doi/10.1073/...
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Luiza Angheluta @luizaangheluta.bsky.social · 18/04/2025
New paper on a field theory for coupling nematic ordering of the actin filaments with tissue elasticity. arxiv.org/abs/2504.10689
arxiv.org
Biomechanics of orientationally ordered epithelial tissue
Organogenesis involves large deformations and complex shape changes that require elaborate mechanical regulation. Models of tissue biomechanics have been introduced to account for the coupling between...
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Stig Ove Bøe @stigoveboe.bsky.social · 08/04/2025
Our new review on topological defects 🌀 in polar active matter is out on arXiv! Co-authored by Luiza Angheluta, Anna Lång, @emmalaang.bsky.social, and @stigoveboe.bsky.social. #ActiveMatter #TopologicalDefects #CollectiveBehavior arxiv.org/abs/2504.03284
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Kyogo Kawaguchi @kyogok.bsky.social · 13/03/2025
Congratulations to Zihui, Sano-san, and the team on this interesting work! They found that +1 topological defects attract neural progenitors—an observation that seems at odds with expectations for an extensile active nematic. www.nature.com/articles/s41...
nature.com
Integer topological defects offer a methodology to quantify and classify active cell monolayers - Nature Communications
The orientation of elongated cells often rotates once around the center in tissue. Such structures are called +1 topological defects and play some roles in biological development. By inducing various ...
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Campàs Lab @campaslab.bsky.social · 24/02/2025
Really excited to present the results of a great collaboration between our group @poldresden.bsky.social and Elliot Hawkes at @ucsantabarbara.bsky.social, which were just published in @science.org. A mix of physics, biology and robotics! 🤖 😀 ▶️ www.science.org/doi/10.1126/...
science.org
Material-like robotic collectives with spatiotemporal control of strength and shape
The vision of robotic materials—cohesive collectives of robotic units that can arrange into virtually any form with any physical properties—has long intrigued both science and fiction. Yet, this visio...
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Rachael Ott @rachaelott.bsky.social · 07/02/2025
For #FluorescenceFriday, large lipid droplets (orange) and alpha-spectrin (blue) are shown in adipocytes 🔬 #Microscopy #CellBiology
Lipid droplets (orange), nuclei (cyan; DAPI), and the cell membrane (blue; α-spectrin) are shown in adipocytes.
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Xavier Trepat @xaviertrepat.bsky.social · 07/02/2025
New paper from the lab🎈. Introducing Micro Immune Response On-chip (MIRO), a device that replicates tumors and their microenvironment to better understand responses to immunotherapies (cyan=immune cells, red=cancer, green=CAFs). www.nature.com/articles/s41... @ibecbarcelona.eu
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Julia Eckert @juliaeckert.bsky.social · 29/01/2025
Thrilled to share our new preprint on detecting the nematic orientation field on surfaces of 3D multicellular systems! www.biorxiv.org/content/10.1... Huge thanks to all authors: @tobyandrews.bsky.social,Joe Pollard, @rashmi-priya.bsky.social, @yap-lab.bsky.social &Richard Morris Any 3D systems?👇
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epithelial mechanics fan club @epimechfc.bsky.social · 17/11/2024
Cells are strong & generate forces while interacting with their environment. Traction Force Microscopy has been instrumental in measuring these forces, revealing the underlying mechanics. Let's explore pioneering papers in this 🧵by @onenimesa.bsky.social & @juliaeckert.bsky.social
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